Clinical Trials on Impaired Health in United Kingdom

Total 32300 results

Royal Devon and Exeter NHS Foundation Trust
University of Exeter

Completed

Increasing Mitochondrial Function on Skeletal Muscle Performance in Older Men (Rejuvenate)

Impaired Mitochondrial Function, Muscle Performance

United Kingdom
University of Exeter
Royal Devon and Exeter NHS Foundation Trust

Terminated

Assessing the Effects of Increased Mitochondrial Function Exercise Training on Muscle Performance (Rejuvenate2)

Impaired Mitochondrial Function, Muscle Performance

United Kingdom
Alexion

Recruiting

Study of ALXN2050 in Participants With Hepatic Impairment

Healthy | Impaired Hepatic Function

United States
University of Birmingham

Completed

Effect of Alveolar-decortication on Velocity of Tooth Movement

Palatally Impacted Canines

United Kingdom
UCB Biopharma S.P.R.L.

Terminated

A Pharmacokinetic Study of Padsevonil in Study Participants With Either Normal or Moderately Impaired Hepatic Function

Impaired Hepatic Function | Healthy Study Participants

United States
Unilever R&D
Aspect Clinical

Completed

Effects of Dietary Ingredients on Vascular Function

Vascular Diseases | Impaired Glucose Tolerance

United Kingdom
University of Leicester
National Institute for Health Research, United Kingdom; National Health Service...

Completed

Breaks in Sedentary Time and Glucose Regulation in Women (ACUTE)

Impaired Glucose Tolerance

United Kingdom
Barts & The London NHS Trust

Withdrawn

ENvarsus for Impaired Glucose Tolerance Post REnal transplAnT (ENTREAT)

Renal Transplant Failure

United Kingdom
Cambridgeshire Community Services NHS Trust
Cambridge University Hospitals NHS Foundation Trust

Unknown

Exploring Interventions for Glue Ear During Covid-19 (BIG-C)

Hearing Loss, Conductive | Hearing Impaired Children | Glue Ear

United Kingdom
Astellas Pharma Europe B.V.
FibroGen

Completed

A Phase 1 Study of Roxadustat in Subjects With Different Degrees of Renal Function

Impaired Renal Function | Normal Renal Function

Germany, United Kingdom
Imperial College London
Pfizer

Completed

Changes in Cerebral Function in Treatment Naive HIV-1 Infected Subjects Commencing Either Boosted Atazanavir With Truvada or Boosted Darunavir With Maraviroc and Kivexa (CogUK)

HIV | Impaired Cognition

United Kingdom
Western Kentucky University

Enrolling by invitation

Evaluation of an Interactive Mobile Phone-Based Brief Intervention to Reduce Substance-Impaired Driving

Driving Impaired

United States
Maimonides Medical Center

Completed

Study of the Need for Temperature Probe Covers for Newborn Babies on Radiant Warmers

Impaired Thermoregulation

United States
Old Dominion University

Completed

Effects of Pre-Exercise Nutrition Strategies on Body Temperature and Thermoregulatory Responses

Impaired Thermoregulation

United States
Cardiology Clinical Research & Regulatory Group

Completed

Heat Retention Head Wrap Use for Re-warming of Infants Requiring Cardio-Pulmonary Bypass

Impaired Thermoregulation

United States
Rhode Island Hospital
Alzheimer's Association

Unknown

Video Feedback Intervention for Cognitively Impaired Older Drivers

Impaired Driving

United States
The Cleveland Clinic
Eisai Inc.

Withdrawn

Fospropofol for Sedation During Elective Awake Intubation

Impaired Airway Clearance

United States
University of California, Irvine
Massachusetts General Hospital; Beckman Laser Institute University of California...

Completed

Immune-Related Trafficking and Signaling in Human Skin Associated With Low-Power, Infrared Laser Treatment

Vaccine Response Impaired

United States
Imperial College London

Completed

Effects of Obesity Surgery on Renal Function

Impaired Renal Function

United Kingdom
University of Pennsylvania
Progressive Auto Insurance

Completed

Reducing Cell Phone Use While Driving Among High Risk UBI Auto Policy Holders

Driving Impaired | Distracted Driving

United States
Western Kentucky University

Completed

An Interactive Text-Message Based Brief Intervention to Reduce Substance-Impaired Driving Among College Students

Alcohol-Impaired Driving

United States
Repros Therapeutics Inc.

Completed

Evaluate the Safety and PK of Proellex® in Female Patients With Impaired Hepatic Function and Healthy Adults

Impaired Liver Function

United States
Genta Incorporated

Completed

Pharmacokinetic Study of Genasense in Subjects With Normal Renal Function, Mildly Impaired Renal Function, and Moderately Impaired Renal Function

Normal Renal Function | Mildly Impaired Renal Function | Moderately Impaired Renal Function

United States
The University of Texas Health Science Center at...

Suspended

Impact of Metformin on Immunity

Aging | Vaccine Response Impaired

United States
NGM Biopharmaceuticals, Inc

Completed

Study of Aldafermin (NGM282) in Participants With Impaired Hepatic Function

Impaired Hepatic Function

United States
Tetraphase Pharmaceuticals, Inc.

Completed

A Phase 1, Open-Label Study to Assess the Single-Dose Pharmacokinetics of Eravacycline in Subjects With Impaired Hepatic Function and Healthy Subjects

Impaired Hepatic Function

United States
Mayo Clinic

Completed

Performance of 13C Mannitol for in Vivo Measurement of Small Intestinal Permeability

Impaired Small Intestinal Permeability

United States
Taiho Oncology, Inc.

Completed

Evaluating Patients With Impaired Hepatic Function

Impaired Hepatic Function

United States
QLT Inc.

Completed

Evaluation of the Effects of Oral QLT091001 in Adults With Impaired Dark Adaptation

Impaired Dark Adaptation

United States
Rush University Medical Center

Completed

Validation of Driving Simulator to Blood Alcohol Concentration Standards for Impaired Driving (ALCDrive)

Impairment | Driving | Intoxication | Alcohol Impaired Driving

United States
University of Aberdeen
King's College London; Zarqa University

Recruiting

The Impact of 3D-CBCT Imaging on Nerve Injuries During Wisdom Tooth Surgery (IMPACTION)

Impacted Third Molar Tooth | Inferior Alveolar Nerve Injuries

United Kingdom
Novartis Pharmaceuticals

Completed

Evaluation of Hepatic Function Impairment on the Pharmacokinetics of LEE011

Normal Hepatic Function | Impaired Hepatic Function

United States
University of Pennsylvania
General Motors (GM)

Completed

Increasing Seat Belt Wearing and Decreasing Handheld Phone Use While Driving

Distracted Driving | Impaired Driving | Driving Behaviors

United States
Neurana Pharmaceuticals, Inc.
Cognitive Research Corporation

Completed

Driving Simulation to Assess Non-Sedative Effects of Tolperisone

Driving Impaired

United States
Novartis Pharmaceuticals

Completed

Effect of Hepatic Impairment on LDE225..

Normal Hepatic Function | Impaired Hepatic Function

Belgium, Germany, Israel, Bulgaria, United States
Stealth BioTherapeutics Inc.

Completed

A Phase 1 Study Investigating the Safety and Pharmacokinetics of Repeat-dose Intravenous Infusion of MTP-131 in Subjects With Impaired Renal Function

Normal and Impaired Renal Function

United States
Norgine

Completed

Movicol in Childhood Constipation (ProMotion Study)

Feces, Impacted

United Kingdom
Unicity International, Inc.
Biofortis Innovation Services

Completed

Effects of an Intermittent Fasting and Dietary Supplement Regimen on Glycemic Variability

Healthy | Impaired Glucose Tolerance

United States
Kemin Foods LC
DSM Nutritional Products, Inc.

Terminated

Effects of Lutein on Visual Function

Healthy | Nutrition Poor

United Kingdom
The University of Texas Health Science Center at...
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); A... and other collaborators

Recruiting

Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

Diabetes Mellitus, Type 2 | Impaired Glucose Tolerance (IGT) | Impaired Fasting Glucose (IFG)

United States
Columbia University

Completed

Effect of Cabergoline on Weight and Glucose Tolerance

Body Weight | Impaired Glucose Tolerance in Obese

United States
US Department of Veterans Affairs

Completed

D Vitamin Intervention in VA (DIVA)

Impaired Glucose Tolerance | Impaired Fasting Glucose | Vitamin D Insufficiency

United States
Exelixis

Completed

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Healthy | Renal Impairment

United States
Brigham and Women's Hospital

Completed

The Effects of Modafinil to Counteract the Adverse Metabolic Consequences of Sleep Restriction

Sleep Restriction | Impaired Glucose Metabolism

United States
The University of Texas Health Science Center at...
Amylin Pharmaceuticals, LLC.

Completed

Acute Effect of Exenatide on Brain Glucose Metabolism

Diabetes | Impaired Glucose Tolerance (IGT)

United States
University of Alabama at Birmingham

Completed

Speed of Processing Training in Adults With HIV (SOP)

HIV | Impaired Driving | Cognition - Other

United States
Chelsea and Westminster NHS Foundation Trust

Completed

Recording by Patients and Relatives/Friends in the Maternity Unit

Healthy | Knowledge, Attitudes, Practice | Maternity | Health Personnel Attitude

United Kingdom
Stanford University

Terminated

Quality of Life in Adults Impaired Functioning - A Randomized Controlled Trial of Bidet vs Usual Toileting

Toileting in Adults With Impaired Functional Status | Caregiver Burden for Those Who Care for Adults With Impaired Functional Status | UTI in Adults With Impaired Functional Status

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study of the Effect of Renal Impairment on the Pharmacokinetics of Isavuconazole.

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Renal Impaired

United States
Mast Therapeutics, Inc.

Completed

Study of the Effect of Renal Impairment on the Pharmacokinetics of Vepoloxamer

Healthy Volunteers | Renal Impaired | Pharmacokinetics of Vepoloxamer

United States

Clinical Trials on Impaired Health in United Kingdom

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