Clinical Trials on Infective Endocarditis in United States

Total 4722 results

Cubist Pharmaceuticals LLC

Completed

Daptomycin Versus Vancomycin in Participants With Skin Infections Due to MRSA (DAPHEOR1006)

Staphylococcal Skin Infections

United States, Puerto Rico
National Institute of Allergy and Infectious Diseases...

Completed

Nerve Damage in Patients With HIV Infection Who Have Been Treated With Anti-HIV Drugs

HIV Infections | Peripheral Nervous System Disease

United States
AbbVie

Completed

A Study of of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus (HCV) Genotype 5 or 6 Infection (ENDURANCE-5 6)

Hepatitis C Virus (HCV)

United States, Australia, Belgium, Canada, France, New Zealand, Singapore, South Africa, Vietnam
Saglik Bilimleri Universitesi Gulhane Tip Fakultesi

Completed

The Microbiologic Profile of Diabetic Foot Infections in Turkey - TURK-DAY (TURK-DAY)

Infection

Turkey
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Evaluate the Effects of Anti-HIV Drugs in HIV-Positive Patients Who Also Have Hepatitis C Infection

HIV Infections | Hepatitis C

United States, Puerto Rico
GlaxoSmithKline

Completed

A Study on the Immune Response and Safety of the Shingles Vaccine and the Influenza Vaccine When Either is Given to Healthy Adults at the Same Time or Following a COVID-19 Booster Vaccine

Herpes Zoster

United States
Alkermes, Inc.

Completed

The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis

HIV Infections | Meningitis, Cryptococcal

United States
AstraZeneca

Completed

A Study in Asthma Patients to Evaluate Efficacy, Safety and Tolerability of 14 Days Once Daily Inhaled Interferon Beta-1a After the Onset of Symptoms of an Upper Respiratory Tract Infection (INEXAS)

Asthma

France, United Kingdom, Korea, Republic of, Argentina, Australia, Spain, Colombia
GlaxoSmithKline

Terminated

Screening Protocol To Determine Eligibility For Studies Of The Chemokine Coreceptor 5 (CCR5) Antagonist GW873140

HIV Infection

United States, Germany, Belgium, Canada, Denmark
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Early-Onset Sepsis Surveillance Study (EOS)

Sepsis | Gram-Negative Bacterial Infections | Gram-Positive Bacterial Infections | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Jiangsu ProteLight Pharmaceutical & Biotechnology...
Parexel

Not yet recruiting

Phase II Study to Evaluate Efficacy and Safety of AMP Peptide PL-5 in Mild Infections of Diabetic Foot Ulcers (PL-5)

Diabetic Foot Ulcers

United States
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Acute Erythroid Leukemia | Acute Megakaryoblastic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myelodysplastic Syndrome With Excess Blasts | Chronic Myelogenous Leukemia, BCR-ABL1... and other conditions

United States
Medicago

Active, not recruiting

Study of a Recombinant Coronavirus-Like Particle COVID-19 Vaccine in Adults

SARS-CoV-2 Infection

United States, Canada, United Kingdom, Argentina, Brazil, Mexico
GlaxoSmithKline

Completed

Study to Assess the Safety and Immunogenicity of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine in Adults Aged 18 Years and Older With Blood Cancers

Herpes Zoster

France, Spain, Taiwan, Belgium, Singapore, United States, Hong Kong, Russian Federation, Finland, Korea, Republic of, Czechia, Australia, Canada, Sweden, Poland, United Kingdom, Panama, Italy, Turkey, Pakistan, New Zealand
Hoffmann-La Roche

Completed

A Randomized, Open-Label Study of Alternative Treatment Combinations of Dideoxycytidine (HIVID; ddC) and Zidovudine (AZT) in Patients With HIV Infection

HIV Infections

United States
GlaxoSmithKline

Completed

A Long-term Follow-up Study (ZOE-LTFU) of Two Studies 110390 (ZOSTER-006) and 113077 (ZOSTER-022) to Assess the Efficacy, Safety, and Immunogenicity Persistence of GSK Biologicals' Herpes Zoster Subunit (HZ/su) Vaccine and Assessment of 1 or 2 Additional Doses in Two Subgroups of Older Adults

Herpes Zoster

United States, Australia, Spain, Finland, Germany, Japan, Taiwan, Sweden, Korea, Republic of, Brazil, Mexico, Canada, Italy, France, Czechia, Estonia, Hong Kong, United Kingdom
Novartis
Novartis Vaccines

Completed

Study to Evaluate the Safety of Novartis MenACWY Conjugate Vaccine When Administered With Routine Infant Vaccinations to Healthy Infants

Meningitis | Meningococcal Infection

United States, China, Costa Rica, Guatemala, Panama, Peru
AbbVie

Completed

A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of ABBV-181 (Budigalimab) in Adult Participants With Human Immunodeficiency Virus (HIV)-1

HIV Infection | HIV-1 | Human Immunodeficiency Virus (HIV)

United States, Australia, Canada, Puerto Rico
Belfast Health and Social Care Trust
Barts & The London NHS Trust; University Hospitals, Leicester; Bristol Royal... and other collaborators

Completed

Febrile Infants - Diagnostic Assessment and Outcome (FIDO)

Bacterial Infections | Urinary Tract Infections | Meningitis, Bacterial

United Kingdom, Ireland
Newcastle-upon-Tyne Hospitals NHS Trust
Wellcome Trust

Completed

Biomarker-based Exclusion of VAP for Improved Antibiotic Stewardship (VAPRapid-2)

Ventilator-associated Pneumonia

United Kingdom
Janssen-Cilag International NV

Completed

A Study of TMC435 Plus Pegylated Interferon Alfa-2a and Ribavirin in Participants With Chronic HCV Infection

Hepatitis C, Chronic | Infection

United Kingdom, Germany, Spain, Belgium, Saudi Arabia, Austria, France
University Hospital Birmingham NHS Foundation Trust
University of Warwick

Completed

Can Continuous Non-invasive Monitoring Improve Stability of Intraoperative Blood Pressure - A Feasibility Study. (iSTABILISE)

Myocardial Ischemia | Hip Fractures | Acute Kidney Injury | Wound Infection | Perioperative/Postoperative Complications | Intraoperative Hypotension | Hypotension on Induction

United Kingdom
AIDS Clinical Trials Group
Bristol-Myers Squibb; National Institute of Allergy and Infectious Diseases... and other collaborators

Completed

Comparative Study of Three NNRTI-Sparing HAART Regimens

HIV Infection

United States, Puerto Rico
Arrevus Inc.

Completed

Oral Sodium Fusidate (CEM-102) Versus Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Acute Bacterial Skin and Skin Structure Infections

United States, Puerto Rico
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Eunice Kennedy... and other collaborators

Recruiting

Long-Term Clinical, Immunologic, and Virologic Profiles of Children Who Received Early Treatment for HIV

HIV Infection

United States, Botswana, Brazil, Haiti, Tanzania, Thailand, Kenya, South Africa, Malawi, Uganda, Zimbabwe
Tibotec Pharmaceuticals, Ireland

Completed

An Open Label Trial of TMC114/RTV in HIV-1 Infected, Treatment-experienced Subjects.

HIV Infection

United States, Australia, France, United Kingdom, Germany, Spain, Belgium, Portugal, Canada, Argentina, Brazil, Austria, Hungary
Pfizer

Completed

A Comparison of the Safety and Effectiveness of Fluconazole or Clotrimazole in the Treatment of Fungal Infections of the Mouth and Throat in Patients With AIDS

HIV Infections | Candidiasis, Oral

United States
Pfizer

Terminated

Study Evaluating Safety and Efficacy of Tigecycline Versus Imipenem/Cilastatin Subjects With Hospital-Acquired Pneumonia

Pneumonia, Bacterial

Canada, United States, Argentina, Australia, Brazil, Chile, Colombia, Croatia, France, Hungary, Korea, Republic of, Latvia, Russian Federation, Taiwan
GlaxoSmithKline

Completed

HerpeVac Trial for Young Women

Herpes Simplex Infection

United States, Canada
St. Bartholomew's Hospital

Unknown

Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease

Myelodysplastic Syndromes | Leukemia | Infection | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
National Institute of Allergy and Infectious Diseases...
Genentech, Inc.; MicroGeneSys Inc (nka Protein Sciences Corporation)

Completed

A Placebo-Controlled, Phase I Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant Envelope Proteins of HIV-1 gp160 and gp120 in Children >= 1 Month Old With Asymptomatic HIV Infection

HIV Infections

United States, Puerto Rico
Gilead Sciences

Completed

Oral Antivirals (GS-5885, Tegobuvir, and/or GS-9451) With Peginterferon Alfa 2a and Ribavirin in Treatment Experienced Subjects With Chronic Genotype 1 Hepatitis C Virus Infection

Hepatitis C, Chronic

United States, Puerto Rico
Pfizer

Completed

Safety and Immunogenicity Study of 20vPnC When Coadministered With a Booster Dose of BNT162b2

COVID-19 | Pneumococcal Disease | SARS-CoV-2 Infection

United States
Insmed Incorporated

Recruiting

Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex (ENCORE)

Mycobacterium Infections, Nontuberculous

Belgium, New Zealand, United Kingdom, United States, Argentina, Australia, Austria, Canada, Chile, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Poland, Spain, Taiwan, Turkey, Portugal
GlaxoSmithKline

Completed

A New Tablet Containing Two FDA-Approved Drugs In HIV-Infected Patients Who Have Not Received Prior Therapy

HIV Infection

United States
Oculus Innovative Sciences, Inc.

Completed

Pilot Study of the Safety and Clinical Efficacy of Topical Dermacyn™ Wound Care to Treat Mild Diabetic Foot Infections

Foot Ulcer, Diabetic

United States
Tissue Tech Inc.

Completed

Phase 2 Pilot Trial of Subjects With Complex Non-healing Diabetic Foot Ulcers Treated With Standard Care Plus Cryopreserved Umbilical Cord Allograft (TTAX01)

Diabetic Foot Infection | Non-healing Wound | Non-healing Diabetic Foot Ulcer

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study to Compare Two Anti-HIV Combination Therapies Each Containing Saquinavir in HIV-Positive Children

HIV Infections

United States, Puerto Rico
GlaxoSmithKline

Active, not recruiting

A Study to Evaluate the Safety and Immunogenicity of GlaxoSmithKline's Herpes Zoster Subunit Vaccine (HZ/su) When Given on a Two-dose Schedule to Adults at Least 50 Years of Age (YOA) Who Had Prior Episode of Shingles

Herpes Zoster

Spain, Panama, Mexico, Russian Federation, Finland, Estonia, Hong Kong, United Kingdom
Atox Bio Ltd
Biomedical Advanced Research and Development Authority

Completed

Phase III Efficacy and Safety Study of AB103 in the Treatment of Patients With Necrotizing Soft Tissue Infections (ACCUTE)

Necrotizing Fasciitis | Necrotizing Soft Tissue Infections | Fournier's Gangrene

United States, France
Novavax

Completed

A Study Looking at the Effectiveness, Immune Response, and Safety of a COVID-19 Vaccine in Adults in the United Kingdom

COVID-19 | SARS-CoV-2 Infection

United Kingdom
GlaxoSmithKline

Completed

A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)

Urinary Tract Infections

Germany, Bulgaria, Spain, United States, Mexico, Slovakia, Romania, Greece, Hungary, United Kingdom, India, Czechia
US Department of Veterans Affairs
Pfizer; United States Department of Defense

Completed

Antibiotic Treatment of Gulf War Veterans' Illnesses

Persian Gulf Syndrome | Mycoplasma Infections

United States, Puerto Rico
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Herpes Zoster (HZ/su) Vaccine in Adults With Solid Tumours Receiving Chemotherapy

Herpes Zoster | Herpes Zoster Vaccine

Canada, Spain, Korea, Republic of, United Kingdom, France, Czechia
Novavax
Bill and Melinda Gates Foundation

Completed

A Study Looking at the Effectiveness and Safety of a COVID-19 Vaccine in South African Adults

COVID-19 | SARS-CoV-2 Infection

South Africa
National Institute of Allergy and Infectious Diseases...
Hoffmann-La Roche; Glaxo Wellcome

Completed

A Randomized, Double Blind, Comparative Study of Dideoxycytidine (ddC) Alone or ddC/AZT Combination Versus Zidovudine (ZDV) Alone in Patients With HIV Infection Who Have Received Prior ZDV Therapy

HIV Infections

United States
OM Pharma SA

Recruiting

OM-85 in Paediatric Recurrent Respiratory Tract Infections With Wheezing Lower Respiratory Illness

Respiratory Tract Infections | Wheezing Lower Respiratory Illness

United Kingdom, Hungary, Poland, Switzerland, Germany, Italy
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Lymphoma | Multicentric Castleman Disease | Plasmablastic Lymphoma | Kaposi Sarcoma | Recurrent Lymphoma | Anal Carcinoma | Recurrent Kaposi Sarcoma | Recurrent Plasmablastic Lymphoma | Transplant-Related Kaposi Sarcoma

United States
Merck Sharp & Dohme LLC

Completed

A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018)

Acute Bacterial Skin and Skin Structure Infections

United States, Brazil, Bulgaria, Georgia, Germany, Guatemala, Latvia, Lithuania, Mexico, Poland, Russian Federation, South Africa, Turkey, Ukraine
National Institute of Allergy and Infectious Diseases...
Glaxo Wellcome

Completed

A Study of Valacyclovir Hydrochloride in the Prevention of Life-Threatening Cytomegalovirus Disease in HIV-Infected Patients

HIV Infections | Cytomegalovirus Infections

United States, Canada, Italy, United Kingdom, Australia, Denmark, France, Germany, Sweden, Switzerland

Clinical Trials on Infective Endocarditis in United States

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