Clinical Trials on Inflammation Vascular

Total 56244 results

DePuy International

Withdrawn

A Multi-centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Polyethylene-on-metal Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures
DePuy International

Terminated

A Two Centre Study to Assess the Stability and Long-term Performance of the C-Stem™ AMT in a Total Primary Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

United Kingdom
DePuy Orthopaedics

Recruiting

Actis Total Hip System 2 Year Follow-up (Actis14014)

Osteoarthritis | Rheumatoid Arthritis | Congenital Hip Dysplasia | Traumatic Arthritis | Avascular Necrosis of the Femoral Head | Acute Traumatic Fracture of the Femoral Head or Neck | Certain Cases of Ankylosis | Non-union of Femoral Neck Fractures | Certain High Sub-Capital & Femoral Neck Fractures...

United States
DePuy International

Terminated

A Multi-centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

Australia, Germany, United Kingdom
DePuy International

Terminated

Multi-Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Resurfacing and Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

Austria, Czech Republic, Finland, Germany, Norway, Portugal, Switzerland, United Kingdom
DePuy International

Terminated

A Randomised Single Centre Study to Compare the Long-term Performance of 4 Designs of the DePuy Ultima LX Stem in Primary Total Hip Replacement

Osteoarthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Traumatic Femoral Fractures | Nonunion of Femoral Fractures | Collagen Disorder

United Kingdom
Central Hospital, Nancy, France

Recruiting

Cognitive Disorders in Hereditary Spastic Paraplegia Type 4 (SPG-TEP)

Spastic Paraplegia

France
University of Texas at Austin

Recruiting

Non-invasive BCI-controlled Assistive Devices

Stroke | Healthy | Muscular Diseases | Movement Disorders | Motor Neuron Disease | Traumatic Brain Injury | Spinal Cord Injuries | Motor Disorders

United States
TMRW Life Sciences
Dudley Associates Healthcare Marketing & Communications

Completed

The U.K. Embryologist Fatigue Study (FUSE-UK)

Gastrointestinal Diseases | Cardiovascular Diseases | Fatigue | Back Pain | Musculoskeletal Pain | Stress | Burnout, Professional | Chest Pain | Neck Pain | Sleep Disturbance | Syncope | Dizziness | Headache | Shortness of Breath

United States
TMRW Life Sciences
Dudley Associates Healthcare Marketing & Communications

Completed

The U.S. Embryologist Fatigue Study (FUSE)

Gastrointestinal Diseases | Cardiovascular Diseases | Fatigue | Back Pain | Musculoskeletal Pain | Stress | Burnout, Professional | Chest Pain | Neck Pain | Sleep Disturbance | Syncope | Dizziness | Headache | Shortness of Breath

United States
Universidade Federal do Rio Grande do Norte

Completed

Detraining in People Living With HIV/AIDS (PVHA)

Sarcopenia | Lipodystrophy Syndrome, HIV

Brazil
St. Marianna University School of Medicine

Unknown

Efficacy and Safety of Tamibarotene(AM80H) for HTLV-1 Associated Myelopathy/ Tropical Spastic Paraparesis (HAM/TSP)

HTLV-I-Associated Myelopathy

Japan
University Health Network, Toronto
Sunnybrook Health Sciences Centre; Western University

Completed

Untreated Sleep Apnea as an Aggravating Factor for Other Secondary Medical Conditions After Spinal Cord Injury

Sleep Apnea | Neuropathic Pain | Spinal Cord Injuries | Spasticity, Muscle | Cardiovascular Complication

Canada
Cambridge University Hospitals NHS Foundation Trust

Unknown

Virtual Environment Rehabilitation for Patients With Motor Neglect Trial (VERMONT)

Stroke | Osteoarthritis | Back Pain | Sciatica | Fibromyalgia | Complex Regional Pain Syndromes | Traumatic Brain Injury

United Kingdom
Viela Bio

Completed

A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis

Systemic Lupus Erythematosus | Systemic Sclerosis | Dermatomyositis | Polymyositis | Sjogren's Syndrome | Cutaneous Lupus Erythematosus

United States, Poland, Spain
Oregon Health and Science University
Jacobus Pharmaceutical

No longer available

3,4-Diaminopyridine for Lambert-Eaton Myasthenic Syndrome (LEMS) and Congenital Myasthenia (CM)

Lambert-Eaton Myasthenic Syndrome (LEMS) | Congenital Myasthenia (CM)

United States
Kyorin University

Completed

Efficacy Study of Water Drinking on PKD Progression. (ESWP)

Disease Progression | Autosomal Dominant Polycystic Kidney Disease

Japan
GTx

Completed

Phase III Study of the Effect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC)

Non Small Cell Lung Cancer | Muscle Wasting

United States
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Nonunion of Femoral Fractures

South Africa
DePuy International

Completed

A Study to Assess the Long-term Performance of SmartSet® HV and SmartSet® GHV Bone Cements in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Slovakia
DePuy International

Terminated

A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

Czech Republic
DePuy International

Terminated

A Two Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Metal-on-Metal Bearing in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

United Kingdom, Italy
DePuy International

Terminated

A Multi-centre Study to Assess the Long-term Performance of the Summit™ Hip in Primary Total Hip Replacement

Osteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Post-traumatic Arthritis | Congenital Hip Dysplasia | Slipped Capital Femoral Epiphysis | Collagen Disorders | Traumatic Femoral Fractures | Nonunion of Femoral Fractures

China, Hong Kong, Italy, Korea, Republic of, New Zealand
Oulu University Hospital
University of Oulu; Academy of Finland; Roche Diagnostics; PerkinElmer, Inc.; Sigrid... and other collaborators

Recruiting

PEPPI Study: Identification of Women at Risk for Placental Dysfunction

Cardiovascular Diseases | Polycystic Ovary Syndrome | Iron-deficiency | Pre-Eclampsia | Intrauterine Growth Restriction | Hypertensive Disorder of Pregnancy | Proteinuria in Pregnancy

Finland
University of the Punjab
Higher Education Commission (Pakistan); Centre of Excellence in Molecular Biology... and other collaborators

Recruiting

Efficacy of Adipose Tissue Derived Stem Cells for the Treatment of Diabetic Foot Ulcers

Diabetes Mellitus | Diabetic Foot | Foot Ulcer | Diabetes Complications | Diabetic Foot Ulcer | Diabetic Foot Infection | Diabetic Foot Ulcer Neuropathic | Foot Ulcer Due to Type 1 Diabetes Mellitus | Foot Ulcer Due to Type 2 Diabetes Mellitus | Chronic Diabetic Ulcer of Left Foot | Chronic Diabetic Foot...

Pakistan
Nkarta Inc.

Recruiting

NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers

Lymphoma, Non-Hodgkin | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia | B-cell Acute Lymphoblastic Leukemia | Small Lymphocytic Lymphoma | Large B-cell Lymphoma | Indolent Lymphoma | Aggressive Lymphoma | Large-cell Lymphoma

United States, Australia
Merck Sharp & Dohme LLC

Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Von Hippel-Lindau Disease | Pancreatic Neuroendocrine Tumor | Pheochromocytoma/Paraganglioma | Advanced Gastrointestinal Stromal Tumor | HIF-2α Mutated Cancers

Canada, United States, Denmark, France, Germany, Hungary, Italy, Russian Federation, Spain, Sweden, Turkey, Israel, United Kingdom, Netherlands, Australia, China, Singapore, Japan
Chimerix
National Institutes of Health (NIH)

Recruiting

Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms

Glioblastoma | Neuroectodermal Tumors | Neuroectodermal Tumors, Primitive | Central Nervous System Neoplasms | Ependymoma | Medulloblastoma | Anaplastic Astrocytoma | Anaplastic Pleomorphic Xanthoastrocytoma | Pleomorphic Xanthoastrocytoma | Oligodendroglioma | Choroid Plexus Neoplasms | Diffuse Astrocytoma | Anaplastic... and other conditions

United States
Scott R. Plotkin, MD, PhD
Takeda; National Comprehensive Cancer Network; The Children's Tumor Foundation

Recruiting

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) (INTUITT-NF2)

Ependymoma | Meningioma | Neurofibromatosis Type 2 | Vestibular Schwannoma | Non-vestibular Schwannoma

United States
National Cancer Institute (NCI)

Recruiting

Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic Cancer

Breast Cancer | Multiple Myeloma | Ovarian Cancer | Non-Small Cell Lung Cancer | Neuroendocrine Tumors | Gastrointestinal/Genitourinary Cancers | Endocrine Tumors

United States
University of Washington
Millennium Pharmaceuticals, Inc.

Active, not recruiting

Ixazomib Citrate and Rituximab in Treating Patients With Indolent B-cell Non-Hodgkin Lymphoma

Follicular Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Small Lymphocytic Lymphoma | Recurrent Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Refractory Extranodal Marginal...

United States
University of Calgary

Completed

ENCOMPASS: Expansion Study B, RCT (ENCOMPASS)

Hypertension | Diabetes Mellitus, Type 2 | Chronic Kidney Diseases | Chronic Obstructive Pulmonary Disease | Asthma | Ischemic Heart Disease | Congestive Heart Failure

Canada
Fundación para la Lucha contra las Enfermedades...
Entelai

Completed

Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology (AIDEN)

Stroke | Delirium | Migraine | Meningitis | Subarachnoid Hemorrhage | Guillain-Barre Syndrome | Trigeminal Neuralgia | Status Epilepticus | Facial Palsy | Vertigo Benign Positional

Argentina
ArQule, Inc., a subsidiary of Merck Sharp & Dohme...

Active, not recruiting

A Study of Nemtabrutinib (MK-1026) in Participants With Relapsed or Refractory Hematologic Malignancies (ARQ 531-101/MK-1026-001)

Lymphoma, B-Cell | Follicular Lymphoma | Waldenstrom Macroglobulinemia | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Richter's Transformation

United States
Children's Hospital Medical Center, Cincinnati
AstraZeneca

Active, not recruiting

Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors (SEL-TH-1601)

Glioma | Ependymoma | Meningioma | Neurofibromatosis 2 | Vestibular Schwannoma

United States
Chang Gung Memorial Hospital

Enrolling by invitation

A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software

Myocardial Infarction | Left Bundle-Branch Block | Atrial Flutter | Left Ventricular Hypertrophy | Long QT Syndrome | Sinus Bradycardia | Right Bundle-Branch Block | Sinus Tachycardia | Premature Atrial Complexes | Premature Ventricular Complexes

Taiwan
Azienda Socio Sanitaria Territoriale degli Spedali...

Completed

Cerebello-Spinal tDCS as Rehabilitative Intervention in Neurodegenerative Ataxia (SCA02)

Ataxia | Multiple System Atrophy | Spinocerebellar Ataxias | Spinocerebellar Ataxia 3 | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Ataxia With Oculomotor Apraxia | CANVAS

Italy
Masonic Cancer Center, University of Minnesota

Completed

Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases

Lymphoma | Acute Myeloid Leukemia | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma | Non-Hodgkin's Lymphoma | Myelofibrosis | Chronic Lymphocytic Leukemia | Acute Lymphocytic Leukemia | MDS | Chronic Myelogenous Leukemia | Prolymphocytic Leukemia | Refractory Anemia

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Donor Lymphocyte Infusion in Treating Patients With Persistent, Relapsed, or Progressing Cancer After Donor Hematopoietic Cell Transplant

Recurrent Hodgkin Lymphoma | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Non-Hodgkin Lymphoma | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Recurrent Plasma Cell Myeloma

United States, Germany, Italy
Universitaire Ziekenhuizen KU Leuven
Norwegian Institute of Public Health; KU Leuven; University Ghent; Sciensano

Completed

Evidence-based Laboratory Test Order Sets in Primary Care

Liver Diseases | Cardiovascular Diseases | Sexually Transmitted Diseases | Hypertension | Obesity | Diabetes Mellitus | Fatigue | Chronic Kidney Diseases | Thyroid Diseases | Rheumatoid Arthritis | Diarrhea | Anemia | Acute Coronary Syndrome | Gout | Lung Embolism | Medication Monitoring | General Check-up

Belgium
Westfälische Wilhelms-Universität Münster
ICON plc

Unknown

Natural History of GACI With or Without ARHR2 or PXE

Pseudoxanthoma Elasticum | Generalized Arterial Calcification in Infancy | Autosomal Recessive Hypophosphatemic Rickets

Germany
CSA Medical, Inc.

Terminated

Interventional Cryotherapy for the Eradication of Benign Airway Disease ("ICE the BAD") (ICEtheBAD)

Lung Diseases, Obstructive | Wegener's Granulomatosis | Sarcoidosis | Recurrent Respiratory Papillomatosis | Rhinoscleroma

United States
Texas Oncology Cancer Center

Terminated

Pooled Unrelated Donor Umbilical Cord Blood Transplant For Hematologic Malignancy Needing Allogeneic Stem Cell Transplant Without Related HLA-Match

Multiple Myeloma | Chronic Lymphocytic Leukemia | Myelodysplastic Syndrome | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Aplastic Anemia | Non-Hodgkins Lymphoma | Hodgkins Disease

United States
Asan Medical Center
Korea Research Institute of Bioscience & Biotechnology

Completed

Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

Korea, Republic of
European Organisation for Research and Treatment...

Terminated

Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Neutropenia | Unspecified Adult Solid Tumor, Protocol Specific | Infection | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Fever, Sweats, and Hot Flashes | Myelodysplastic/Myeloproliferative Neoplasms

France, Switzerland, Belgium, Germany, Italy, Israel, Slovakia, Turkey
University Hospital, Ioannina
1st Division of Internal Medicine, University Hospital of Ioannina

Recruiting

University Hospital of Ioannina COVID-19 (Coronavirus Disease 2019) Registry

COVID-19 Pneumonia | COVID-19 Respiratory Infection | COVID-19 Pandemic | COVID-19 Acute Respiratory Distress Syndrome | COVID-19-Associated Pneumonia | COVID 19 Associated Coagulopathy | COVID-19 (Coronavirus Disease 2019) | COVID-19-Associated Thromboembolism

Greece
John Lister
Miltenyi Biotec, Inc.; Lentigen Technology, Inc.; AHN (Allegheny Health Network)...

Recruiting

Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia

Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Chronic Lymphocytic Leukemia | Lymphoplasmacytic Lymphoma | Diffuse Large B Cell Lymphoma | B Acute Lymphoblastic Leukemia | B-Cell Lymphoma | Transformed Lymphoma

United States
Biomea Fusion Inc.

Recruiting

Study of BMF-219, a Covalent Menin Inhibitor, in Adult Patients With AML, ALL (With KMT2A/ MLL1r, NPM1 Mutations), DLBCL, MM, and CLL/SLL

Lymphoma | Lymphoma, Non-Hodgkin | Acute Myeloid Leukemia | Cancer | Progression | Multiple Myeloma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Plasma Cell Myeloma | Diffuse Large B Cell Lymphoma | Small Lymphocytic Lymphoma | Refractory | Myeloma, Plasma-Cell | Myelomatosis | Acute Mixed-Phenotype...

United States, Spain, Netherlands, Greece, Italy
Stephen G. Kaler, MD

Recruiting

NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn Syndrome

Menkes Disease | Occipital Horn Syndrome

United States

Clinical Trials on Inflammation Vascular

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