Clinical Trials on Inflammatory Reaction

Total 11521 results

University Hospital, Montpellier

Completed

Longitudinal Follow-up of Patients With Chronic Inflammatory Rheumatisms (CIRs) Vaccinated Against COVID-19 Compared to Patients Refusing Vaccination (COVID-RIC3)

COVID-19 | Rheumatic Diseases | SARS-CoV Infection

France
Christian Hassager

Completed

Steroid Treatment After Resuscitated Out-of-Hospital Cardiac Arrest (STEROHCA)

Systemic Inflammatory Response Syndrome | Cardiac Arrest | Out-Of-Hospital Cardiac Arrest | Neurological Injury | Cardiac Arrest With Successful Resuscitation | Post Cardiac Arrest Syndrome

Denmark
Johns Hopkins University

Terminated

Smartphone Mindfulness Meditation for Patients With Rheumatic Diseases

Systemic Lupus Erythematosus | Vasculitis | Inflammatory Arthritis | Myositis | Sjogren's Syndrome | Scleroderma

United States
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

Effect of R-spondin3 on Sepsis Induced Endothelial Dysfunction

Acute Respiratory Distress Syndrome (ARDS) | Acute Lung Injury (ALI)

China
Novartis Pharmaceuticals

Terminated

Ceritinib Rare Indications Study in ALK+ Tumors

Glioblastoma | Anaplastic Large Cell Lymphoma | Inflammatory Myofibroblastic Tumor | Tumors With Aberrations in ALK

France, Czechia, Italy, Spain, Korea, Republic of, Thailand, Israel, Denmark
Maimonides Medical Center

Recruiting

Guanfacine Extended Release for the Reduction of Aggression and Self-injurious Behavior Associated With Prader-Willi Syndrome (PWS-GXR)

Aggression | Behavioral Symptoms | Pathologic Processes | Nervous System Diseases | Obesity | Neurologic Manifestations | Neurobehavioral Manifestations | Congenital Abnormalities | Overnutrition | Nutrition Disorders | Genetic Diseases, Inborn | Intellectual Disability | Self-Injurious Behavior | Abnormalities, Multiple and other conditions

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Radiomics Markers to Predict Sepsis Induced Acute Respiratory Distress Syndrome

Early Prediction for Sepsis Induced Acute Lung Injury

China
Diakonhjemmet Hospital
University Hospital, Akershus

Active, not recruiting

Vaccine Response to COVID-19 Vaccines in Patients Using Immunosuppressive Medication (Nor-vaC)

Rheumatoid Arthritis | Crohn Disease | Ulcerative Colitis | Autoimmune Hepatitis | Psoriatic Arthritis | Liver Transplant; Complications | Spondyloarthritis

Norway
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Germany, France, Belgium, Canada, Spain, Switzerland, United Kingdom
University Hospital, Clermont-Ferrand

Completed

Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients

Septic Shock | Acute Respiratory Distress Syndrome | Acute Lung Injury | Severe Sepsis | Mechanical Ventilation

France
Crinetics Pharmaceuticals Inc.

Active, not recruiting

Study to Evaluate the Safety, PK, and Dose Response of Paltusotine in Subjects With Carcinoid Syndrome

Carcinoid Tumor | Carcinoid Syndrome | Carcinoid | Carcinoid Tumor of Ileum | Carcinoid Tumor of Cecum | Carcinoid Syndrome Diarrhea | Carcinoid Intestine Tumor | Carcinoid Tumor of Liver | Carcinoid Tumor of Pancreas

United States, Brazil, Argentina, Canada, Mexico, Peru, Poland
Jack Khouri

Not yet recruiting

Siltuximab for Cytokine Release Syndrome Prophylaxis Prior to tx w/ Teclistamab in RRMM

Multiple Myeloma | Refractory Multiple Myeloma | Cytokine Release Syndrome | Immune Effector Cell Associated Neurotoxicity Syndrome

United States
Indiana University
National Heart, Lung, and Blood Institute (NHLBI); University of California... and other collaborators

Not yet recruiting

SHADES Mechanistic Trial (SHADES)

Heart Diseases | Cardiovascular Diseases | Coronary Artery Disease | Stroke | Sleep Disorder | Insomnia | Sleep Disturbance | Metabolic Disease | Autonomic Dysfunction | Insomnia Chronic | Systemic Inflammatory Response | Insomnia, Primary

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety Study of Canakinumab Administered for 6 Months (24 Weeks) in Japanese Patients With Cryopyrin-associated Periodic Syndromes Followed by an Extension Phase

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Japan
University Hospital, Toulouse

Unknown

Fertility Study of Women With Chronic Inflammatory Rheumatism (FERTIRHUM)

Arthritis, Rheumatoid | Arthritis, Psoriatic | Ankylosing Spondylitis | Chronic Juvenile Arthritis

France
Rempex (a wholly owned subsidiary of Melinta Therapeutics...

Completed

Study of Cases of Serious Infections Due to Carbapenem-Resistant Enterobacteriaceae

Bacteremia | Acute Pyelonephritis | Ventilator-associated Bacterial Pneumonia | Hospital Acquired Bacterial Pneumonia | Urinary Tract Infection, Complicated

Italy, United States, Greece, United Kingdom
Diakonhjemmet Hospital
South-Eastern Norway Regional Health Authority

Completed

The NOR-SWITCH Study (NOR-SWITCH)

Rheumatoid Arthritis | Crohn's Disease | Ulcerative Colitis | Psoriatic Arthritis | Spondyloarthritis | Psoriasis Chronic

Norway
Novartis Pharmaceuticals

Completed

Efficacy, Safety and Tolerability of ACZ885 in Pediatric Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Muckle-Wells Syndrome | Neonatal Onset Multisystem Inflammatory Disease | Cryopyrin-associated Periodic Syndromes

Germany, France, Belgium, Canada, Spain, Switzerland, United Kingdom
Chang Gung Memorial Hospital

Unknown

EVLWI Exhibits Pulmonary and Systemic Permeability in Sepsis Related ALI/ARDS

Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome

Taiwan
Mahidol University

Completed

Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS)

Septic Shock | Acute Respiratory Distress Syndrome | Acute Lung Injury | Severe Sepsis

Thailand
University of California, Los Angeles

Unknown

Cysteine Supplementation in Critically Ill Neonates

Sepsis | Systemic Inflammatory Response Syndrome | Necrotizing Enterocolitis | Retinopathy of Prematurity | Bronchopulmonary Dysplasia

United States
Seoul National University Hospital

Recruiting

Assessment of Quality of Life After Low Anterior Resection During Cytoreductive Surgery for Advanced Ovarian Cancer (LAPSODY)

Quality of Life | Ovarian Cancer | Low Anterior Resection Syndrome

Korea, Republic of
Barts & The London NHS Trust

Terminated

CGM (Continuous Glucose Monitoring) Use in Diagnosis of Spontaneous and Reactive Hypoglycaemia

Insulin Resistance | Insulinoma | Hypoglycemia Unawareness | Hypoglycemia Non-Diabetic | Insulin Hypoglycemia | Hypoglycemia, Reactive | Hypoglycaemia Night | Insulinoma; Malignant, Pancreas | Spontaneous Hypoglycemia | Neuro Endocrine Tumours

United Kingdom
University Medical Centre Ljubljana

Unknown

Changes in Haemostasis After Therapeutic Plasmapheresis With Citrate Anticoagulation

Guillain-Barre Syndrome | Humoral Rejection | CIDP | Miller Fisher Syndrome | Good Pasture Syndrome | Hyperviscosity Syndrome

Slovenia
Ain Shams University

Recruiting

Assessment Of Dose-Dependent Immunomodulatory Effect Of Alveofact With or Without Steroisd In Neonatal RDS

Inflammatory Response | Preterm Birth | Premature Lungs | Neonatal Respiratory Distress Syndrome | Neutrophil Extracellular Trap Formation

Egypt
Croatian Society for Organ Support
Clinical Hospital Centre Zagreb

Recruiting

European Registry for Hemadsorption in Sepsis With the Seraph Filter

Sepsis | Systemic Inflammatory Response Syndrome | Disease | Critical Illness | Acute Respiratory Distress Syndrome | Multi Organ Failure | Infections - Pathogen Unspecified

Croatia
University of Ulm

Recruiting

Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis (MIPSA)

Sepsis | Critically Ill | Pseudomonas Infections | Sepsis, Severe | Pseudomonas Septicemia | Pseudomonas; Pneumonia | Pseudomonal Bacteraemia | Pseudomonas Urinary Tract Infection | Pseudomonas Gastrointestinal Tract Infection

Germany
Onze Lieve Vrouwe Gasthuis
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Active, not recruiting

Parental Participation on the Neonatal Ward - the neoPARTNER Study (neoPARTNER)

Infant, Premature, Diseases | Premature Birth | Parent-Child Relations | Parents | Infant, Newborn, Disease | Prematurity | Neonatal Hyperbilirubinemia | Infant Development | Neonatal Infection | Premature | Neonatal Sepsis | Infant, Small for Gestational Age | Maternal Distress | Perinatal Problems | Small for Gestational...

Netherlands
Biogen

Completed

A Real-world Study of Imraldi® Use (PROPER)

Arthritis, Rheumatoid (RA) | Arthritis, Psoriatic (PsA) | Crohn's Disease (CD) | Colitis, Ulcerative (UC) | Axial Spondyloarthritis (axSpA)

Italy, United Kingdom, Germany, Belgium, Spain, Ireland
Karolinska Institutet
University of California, San Diego; The Swedish Research Council; University... and other collaborators

Terminated

Safety and Efficacy of Hyperbaric Oxygen for ARDS in Patients With COVID-19 (COVID-19-HBO)

COVID-19 | Cytokine Storm | SARS (Severe Acute Respiratory Syndrome) | Acute Respiratory Failure | ARDS, Human | Sars-CoV2

Sweden, Germany
Eastern Virginia Medical School

Terminated

Effect of Sterile Versus Clean Gloves Intrapartum and Postpartum Infections at Term

Chorioamnionitis | Puerperal Infection | Postpartum Endometritis | Intrauterine Infection

United States
Cook County Health
Centers for Disease Control and Prevention; Sage Products, Inc.

Completed

Skin Cleansing With Chlorhexidine to Decrease Hospital Acquired Infections

Pneumonia | Sepsis | Bacteremia | Urinary Tract Infection | Nosocomial Infection | Clostridium Infection

United States
University of Pecs

Completed

Presepsin:Gelsolin Ratio in Sepsis-related Organ Dysfunction

Sepsis | Septic Shock | Acute Respiratory Distress Syndrome | Acute Kidney Injury Due to Sepsis

Hungary
Shionogi

Completed

Study of Cefiderocol (S-649266) or Best Available Therapy for the Treatment of Severe Infections Caused by Carbapenem-resistant Gram-negative Pathogens (CREDIBLE - CR)

Sepsis | Bloodstream Infections (BSI) | Hospital Acquired Pneumonia (HAP) | Complicated Urinary Tract Infection (cUTI) | Healthcare-associated Pneumonia (HCAP) | Ventilator Associated Pneumonia (VAP)

United States, Brazil, Croatia, France, Germany, Greece, Guatemala, Israel, Italy, Japan, Korea, Republic of, Spain, Taiwan, Thailand, Turkey, United Kingdom
Hellenic Institute for the Study of Sepsis
European Commission

Completed

Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System (INCLASS)

Pneumonia | Sepsis | Mortality | Biomarkers | Respiratory Distress Syndrome | Multiple Organ Failure | Gram-Negative Bacteria Infection

Greece, Belgium
Wake Forest University Health Sciences

Withdrawn

Telemedicine for Early Detection of Cytokine Release Syndrome and Neurotoxicity

Follicular Lymphoma | Diffuse Large B Cell Lymphoma | High-grade B-cell Lymphoma | Primary Mediastinal Large B Cell Lymphoma | Large B-cell Lymphoma
Central Hospital, Nancy, France

Unknown

Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic Surgery (RELASTANCE)

Shock, Septic | Aortic Stenosis | Oliguria | Aortic Aneurysm, Abdominal | Hyperlactatemia | Aortic Aneurysm, Ruptured

France
Xiaoxiang Chen

Unknown

Efficacy and Safety of Niraparib Combined With Bevacizumab in Platinum Refractory/Resistant Recurrent Ovarian Cancer (AVANIRA3)

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Endocrine System Diseases | Ovarian Diseases | Adnexal Diseases | Gonadal Disorders | Endocrine Gland Neoplasms | Ovarian Neoplasms | Fallopian Tube Neoplasms and other conditions

China
Washington University School of Medicine
National Cancer Institute (NCI); Incyte Corporation; American Society of Hematology

Active, not recruiting

Study of Itacitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Myelodysplastic Syndromes | Hodgkin Disease | Non-Hodgkin Lymphoma | Acute Lymphocytic Leukemia | Acute Myelogenous Leukemia

United States
Mayo Clinic

Enrolling by invitation

Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

Autoimmune Diseases | Diabetes | Chronic Kidney Diseases | Tobacco Use | Overweight or Obesity | Inflammatory Disease | MRSA | Infections Joint Prosthetic | MSSA Colonization

United States
University Hospital, Bordeaux
Societe Francaise de Rhumatologie

Completed

Impact of COVID-19 Pandemic and Social Distancing on Mental Health of Chronic Inflammatory Rheumatism Affected Patients (EMOPTION)

Covid19 | Rheumatic Fever | Mental Disorder

France
Poitiers University Hospital

Active, not recruiting

Survey About Diet in Chronic Inflammatory Rheumatic Diseases

Rheumatoid Arthritis | Psoriatic Arthritis | Spondylitis, Ankylosing | Feeding Behavior | Diet Habit | Spondyloarthritis | Inflammatory Rheumatism | Rheumatic Disease | Rheumatic Disorder

France
National Institute of Cancerología
Instituto Nacional de Enfermedades Respiratorias

Completed

Impact of Valganciclovir on Severe IRIS-Kaposi Sarcoma Mortality: an Open-label, Parallel, Randomized Controlled-trial.

Kaposi Sarcoma | Human Immunodeficiency Virus | Immune Reconstitution Syndrome

Mexico
UCB BIOSCIENCES, Inc.
Syneos Health; Parexel

Terminated

UCB Cimzia Pregnancy Follow-up Study

Rheumatoid Arthritis (RA) | Crohn's Disease (CD) | Psoriatic Arthritis (PsA) | Axial Spondyloarthritis and Ankylosing Spondylitis

United States
Charite University, Berlin, Germany

Unknown

Subjective Near-infrared Fluorescence Guidance in Perfusion Assessment of Ileal Pouch Formation and Ileal-pouch-anal Anastomosis

Colorectal Cancer | Crohn Disease | Ulcerative Colitis | Familial Adenomatous Polyposis | Crohn Colitis | Ileal Pouch

Germany
Aga Khan University
The International Federation of Red Cross and Red Crescent Societies

Completed

Strengthening Maternal Neonatal and Child Health Services in a Rural District of Pakistan (SRC)

Pneumonia | Anemia | Eclampsia | Postpartum Hemorrhage | Diarrhoea | Neonatal Sepsis | Birth Asphyxia | Antepartum Hemorrhage
Rempex (a wholly owned subsidiary of Melinta Therapeutics...
Department of Health and Human Services

Completed

Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults

Bacteremia | Acute Pyelonephritis | Ventilator-associated Bacterial Pneumonia | Urinary Tract Infection Complicated | Hospital Acquired Bacterial Pneumonia | Abdominal Infection

Italy, United States, Colombia, Greece, Israel, Brazil, Argentina, United Kingdom
Novartis

Completed

Efficacy and Safety of ACZ885 in Patients With the Following Cryopyrin-associated Periodic Syndromes: Familial Cold Autoinflammatory Syndrome, Muckle-Wells Syndrome, or Neonatal Onset Multisystem Inflammatory Disease

Familial Cold Autoinflammatory Syndrome | Cryopyrin-Associated Periodic Syndromes | Neonatal Onset Multisystem Inflammatory Disease | Muckle Wells Syndrome

United States, Germany, Italy, Spain, United Kingdom, Turkey, France, Belgium, India
Centre Hospitalier Universitaire de Nīmes

Completed

Immune Response of Patients With Chronic, Staphylococcus Aureus-infected Wounds (ORISA)

Diabetic Foot | Foot Ulcer | Leg Ulcer | Bacteremia | Infection

France
Beth Israel Medical Center

Terminated

The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study

Pneumonia | Cystitis | Bacteremia | Surgical Wound Infection | Enterocolitis, Pseudomembranous

United States

Clinical Trials on Inflammatory Reaction

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cote d'Ivoire

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations