Clinical Trials on Inherited Platelet Disorder

Total 143827 results

Novo Nordisk A/S

Completed

Safety, Tolerability, and Pharmacokinetics Study of Turoctocog Alfa Pegol Injected Under the Skin in Patients With Haemophilia A (alleviate 1)

Congenital Bleeding Disorder | Haemophilia A

United States, Austria, Serbia, Germany, Japan, France
Novo Nordisk A/S

Completed

Safety of Monthly Recombinant Factor XIII Replacement Therapy in Subjects With Congenital Factor XIII Deficiency: An Extension to Trial F13CD-1725 (mentor™2)

Congenital Bleeding Disorder | Congenital FXIII Deficiency

France, United States, Israel, Spain, Switzerland, Germany, Canada, Japan, United Kingdom, Italy, Finland, Austria
Novo Nordisk A/S

Completed

Trial Investigating Safety, Pharmacokinetics and Pharmacodynamics of Concizumab Administered Subcutaneously to Haemophilia A Subjects

Congenital Bleeding Disorder | Haemophilia A

United States, Netherlands, Austria, Spain, Poland, United Kingdom, Croatia, Germany, Malaysia, Australia, France, Israel, Thailand, Ukraine, Turkey
Novo Nordisk A/S

Completed

Safety and Efficacy of Turoctocog Alfa in Previously Treated Male Children With Haemophilia A (guardian™ 3)

Congenital Bleeding Disorder | Haemophilia A

United States, Macedonia, The Former Yugoslav Republic of, Serbia, Malaysia, Brazil, Turkey, Lithuania, Russian Federation, Italy, Japan, Poland, Puerto Rico, Taiwan
Novo Nordisk A/S

Completed

A Single Dose Trial of Recombinant Factor VIII (N8) in Japanese Subjects With Haemophilia A: An Extension to Trial NN7008-3543

Congenital Bleeding Disorder | Haemophilia A

Japan
Centre Hospitalier Universitaire Dijon

Completed

Platelet Activation by a Collagen Analogue in Hemorrhagic Situations (CAPTURE)

Hemorrhage | Platelet Activation | Collagen Analog

France
Novartis Pharmaceuticals

Completed

A Rollover Study to Provide Continued Treatment With Eltrombopag

Thrombocytopaenia

Belgium, Greece, Netherlands, Romania, China, Korea, Republic of, Tunisia, France, Hong Kong, Ireland, Peru, Poland
University of Copenhagen
Rigshospitalet, Denmark; Glostrup University Hospital, Copenhagen

Completed

Effects of Exercise Training on Cardiovascular Health in Middle-aged Women

Cardiovascular Diseases | Metabolic Diseases | Blood Platelet Disorders | Menopause | Cardiac Function Impaired

Denmark
Sanquin Research & Blood Bank Divisions

Completed

Efficacy of Transfusions With Platelets Stored in Platelet Additive Solution II Versus Plasma

Thrombocytopenia | Myelosuppression | Hemato-Oncologic Patients

Netherlands
University Hospital, Angers

Recruiting

Pilot Study for the Development of a Diagnostic Score to Differentiate Myeloproliferative Neoplasms. (BioScoreSMP)

Essential Thrombocythemia | Myeloproliferative Disorder | Primary Myelofibrosis, Prefibrotic Stage | Primary Myelofibrosis, Fibrotic Stage

France
Innostellar Biotherapeutics Co.,Ltd

Recruiting

Fellow-eye Study (FE) of LX101 in Subjects With Inherited Retinal Dystrophy

Inherited Retinal Dystrophy

China
Shire

Completed

Safety and Pregnancy Outcomes in Thrombocythemia Patients Exposed to XAGRID® (Anagrelide Hydrochloride) Compared to Other Treatments

Thrombocythemia, Essential

Spain, United Kingdom, Greece, Denmark, Italy, France, Finland, Norway, Sweden, Germany, Cyprus, Ireland, Netherlands, Portugal
Azienda Ospedaliera Universitaria Integrata Verona

Completed

Elevated Platelet Count as Prognostic Factor in Colorectal Cancer With Synchronous Liver Metastases (PLTCRC)

Colorectal Cancer | Colorectal Carcinoma | Stage IV Colon Cancer

Italy
Azienda Sanitaria-Universitaria Integrata di Udine

Unknown

Immune Thrombocytopenia (ITP) Immune-Genetic Assessment (UNIT)

Thrombocytopenia

Italy
Shanghai Children's Medical Center
Xiamen Amoytop Biotech Co., Ltd.

Completed

Effect of rhIL-11 in Patients With Thrombocytopenia for Childhood ALL

Pancytopenia Due to Chemotherapy

China
Novo Nordisk A/S

Completed

Study Investigating Novoeight®/NovoEight® (Turoctocog Alfa) in Mexican Haemophilia A Patients

Congenital Bleeding Disorder | Haemophilia A

Mexico
Novo Nordisk A/S

Terminated

A Multi-centre, Open Labelled, Multiple Dosing Trial Investigating Safety, Pharmacokinetics and Pharmacodynamics of NNC 0172-2021 Administered Subcutaneously to Healthy Male Subjects and Haemophilia Subjects (explorer™2)

Healthy | Congenital Bleeding Disorder | Haemophilia A

Austria, Spain, United Kingdom, France, Germany
Novo Nordisk A/S

Completed

Evaluating the Pharmacokinetics of NovoEight® (Turoctocog Alfa) in Relation to BMI in Subjects With Haemophilia A (guardian ™9)

Congenital Bleeding Disorder | Haemophilia A

Austria, Spain, United States, Germany, Serbia, Taiwan, Bulgaria
Novo Nordisk A/S

Completed

A Multi-centre, Comparative, Double Blind, Randomised Cross-over Trial Investigating Single Dose Pharmacokinetics and Safety of Turoctocog Alfa Pegol From the Pivotal Process and Turoctocog Alfa Pegol From the Commercial Process in Patients With Severe Haemophilia A (pathfinder™7)

Congenital Bleeding Disorder | Haemophilia A

United States, Netherlands, Spain, Germany, France, Denmark
Rajavithi Hospital

Recruiting

The Effects of Autologous Platelet-rich Plasma Supplement During Sperm Cryopreservation on Post-cryopreserved Sperm Quality

Autologous Platelet-rich Plasma Supplement | Sperm Cryopreservation | Post-cryopreserved Sperm Quality | Semen Analysis

Thailand
University of California, Los Angeles

Completed

Platelet Function on Abacavir and Tenofovir

Cardiovascular Diseases | HIV/AIDS | Platelet Aggregation, Spontaneous

United States
Harokopio University

Unknown

Cardioprotective Properties of Natural Anti-Platelet Activating Factor Extract From Winery By-products in Healthy Women (NAPE)

Platelet Aggregation and Inflammation

Greece
Dallas VA Medical Center

Completed

Safety of Continuing Anti-platelet Agents During Colonoscopic Polypectomy: A Prospective Study

Colonoscopy | Post-polypectomy Bleeding | Anti-platelet Therapy

United States
Stanford University
Alagille Syndrome Alliance

Enrolling by invitation

Decreasing Hemorrhage Risk in Children With Alagille Syndrome

Alagille Syndrome | Acquired Von Willebrand Disease | Pulmonary Artery Stenoses

United States
National Institute of Allergy and Infectious Diseases...

Completed

Donor Stem Cell Transplantation for Congenital Immunodeficiencies

Inherited Immune Deficiencies

United States
Oregon Health and Science University

Completed

Motor Proficiency of People With Bleeding Disorders Using the BOT-2 (TM)

Hemophilia

United States
Shenyang Sunshine Pharmaceutical Co., LTD.

Not yet recruiting

A Phase Ib Clinical Study for rhTPO in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease

Thrombocytopenia | Liver Disease Chronic

China
Sohag University
Assiut University; Kyoto University

Recruiting

Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes

Inherited BMF Syndrome

Egypt
Medical University of Vienna

Recruiting

Argatroban Monitoring in Critically Ill Patients: Evaluation of a Novel Ecarin-based Bedside Test

Heparin-induced Thrombocytopenia

Austria
Emory University

Terminated

PRevention Of BLeeding in hEmatological Malignancies With Antifibrinolytic (Epsilon Aminocaproic Acid) (PROBLEMA)

Thrombocytopenia | Hematological Malignancies

United States
Peking Union Medical College Hospital

Unknown

A Randomized Trial of rhTPO Versus Placebo for Low/Intermediate-1 Risk MDS With Thrombocytopenia

Low/Intermediate Risk-1 MDS

China
Novo Nordisk A/S

Completed

To Investigate Safety and Efficacy of NovoEight® (rFVIII) During Long-term Treatment of Haemophilia A in Japan

Congenital Bleeding Disorder | Haemophilia A

Japan
Novo Nordisk A/S

Completed

Safety and Efficacy of Turoctocog Alfa During Long-Term Treatment of Severe and Moderately Severe Haemophilia A (guardian™ 5)

Congenital Bleeding Disorder | Haemophilia A

Italy, Sweden, Netherlands, Austria, Spain, United States, Switzerland, Germany, France, Hungary, Greece, Slovenia, Czechia, Slovakia, Poland
Novo Nordisk A/S

Completed

Comparison of the Action of Drugs in the Body and Safety of N8 and Advate® in Haemophilia A Subjects

Congenital Bleeding Disorder | Haemophilia A

Spain, Germany, Switzerland, Italy, Israel
Novo Nordisk A/S

Completed

Safety and Pharmacokinetics of NNC 0129-0000-1003 in Subjects With Haemophilia A (pathfinder™1)

Congenital Bleeding Disorder | Haemophilia A

United States, Germany, Switzerland, United Kingdom, Italy, Japan, Turkey
Novo Nordisk A/S

Completed

Investigation of the Pharmacokinetics of Turoctocog Alfa in Subjects With Haemophilia A

Congenital Bleeding Disorder | Haemophilia A

Spain, Germany, Malaysia, Latvia
Novo Nordisk A/S

Completed

A Single Dose Trial of NNC 0155-0000-0004 in Patients With Haemophilia A

Congenital Bleeding Disorder | Haemophilia A

United Kingdom, Malaysia
Novo Nordisk A/S

Completed

Treatment of Congenital Factor VII Deficiency (F7CONDEF)

Congenital Bleeding Disorder | Congenital FVII Deficiency

Slovakia, Israel, Spain, India, Iran, Islamic Republic of, Pakistan, Turkey, Germany, Serbia, Italy, Greece, Thailand, France, United States, Hong Kong, Venezuela
Duke University
Terumo BCT

Completed

High Yield Intraoperative, Autologous Platelet Apheresis

Allogenic Transfusion of Platelets During Cardiac Surgery

United States
Memorial Sloan Kettering Cancer Center
Sanofi

Recruiting

Open-Label, Phase II Trial of Isatuximab for Patients With Refractory Immune Cytopenias After Allogeneic Hematopoietic Cell Transplantation

Blood Cancer | Refractory Immune Cytopenias

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Enasidenib in People With Clonal Cytopenia of Undetermined Significance

Clonal Cytopenia of Undetermined Significance | CCUS Clonal Cytopenia of Undetermined Significance

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients

Thrombocytopenia | Anemia, Aplastic | Anemia, Hypoplastic

United States
Galena Biopharma, Inc.

Completed

A Study of Anagrelide Controlled Release (GALE-401) in Patients With High Platelet Counts Due to Bone Marrow Disorders

Thrombocytosis | Myeloproliferative Neoplasms

United States
October 6 University

Completed

Effect of Symphysis Onlay Bone Graft, Injectable Platelet Rich Fibrin (I-PRF) and Xenograft on Horizontal Alveolar Ridge Augmentation in Esthetic Zone

Platelet Rich Fibrin | Esthetic Zone | Symphysis Onlay Bone Graft | Xenograft | Horizontal Alveolar Ridge Augmentation

Egypt
Bloodworks
United States Department of Defense

Active, not recruiting

Reversal of Aspirin Antiplatelet Therapy With Cold Stored Platelets (RASP)

Reversal of Platelet Aggregation Inhibitors

United States
La Tour Hospital
Rive Droite SA

Unknown

In Vivo Clinical and Radiological Effects of Platelet-rich Plasma on Interstitial Supraspinatus Lesion: Randomized Study (PRP Randomized)

Platelet-rich Plasma (PRP) | Supraspinatis Interstitial Partial-thickness Tears

Switzerland
University Medical Center Groningen

Active, not recruiting

Image Guided Surgery in Sinonasal Inverted Papilloma (SNIPER)

Inverted Papilloma | Molecular Fluorescence Imaging

Netherlands
Second Hospital of Shanxi Medical University

Not yet recruiting

Clinical Study on the Efficacy and Safety of Hetropapa Ethanolamine Tablets in the Treatment of Thrombocytopenia Caused by Concurrent Radiotherapy and Chemotherapy in Cervical Cancer

Tumor Chemotherapy-related Thrombocytopenia

China
Shionogi

Completed

Safety and Efficacy Study of Lusutrombopag for Thrombocytopenia in Patients With Chronic Liver Disease Undergoing Elective Invasive Procedures (L-PLUS 2)

Thrombocytopenia | Chronic Liver Disease
McMaster University

Terminated

Rivaroxaban for Treatment of Patients With Suspected or Confirmed Heparin-Induced Thrombocytopenia

Heparin-induced Thrombocytopenia

Canada

Clinical Trials on Inherited Platelet Disorder

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