Clinical Trials on Inhibition Enzyme
Total 386 results
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CSL BehringCompletedEmphysema | Alpha1-proteinase Inhibitor DeficiencyAustralia, Russian Federation, United States, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden, Canada, Czech Republic
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German Cancer Research CenterUniversity Hospital HeidelbergRecruitingPancreatic Cancer | Pancreatic Adenocarcinoma | CYP3A Inhibitor | Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma | Pancreatic NeoplasmGermany
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Nanfang Hospital of Southern Medical UniversityPeking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaboratorsUnknownAllogeneic Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Philadelphia Chromosome Positive Acute Lymphocytic Leukemia | Tyrosine Kinase InhibitorChina
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PfizerCompletedTuberculosis | Non-tuberculous Mycobacterial Diseases | Inhibition of Disseminated Mycobacterium Avium Complex Disease Associated With HIV Infections
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Shanghai Jiao Tong University School of MedicineCompletedOral Cancer | Induction Chemotherapy | Programmed Cell Death 1 Inhibitor | Inductive TherapyChina
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Stanley Jordan, MDCSL BehringCompletedKidney TransplantationUnited States
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Pharming Technologies B.V.University of Wisconsin, MadisonWithdrawnKidney Transplantation | Graft RejectionUnited States
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Hospital Universitari Vall d'Hebron Research InstituteErasme University Hospital; Cyprus Institute of Neurology and Genetics; EuroBloodNet...RecruitingIron Metabolism Disorders | Sickle Cell Disease | Thalassemia | Hemolytic; Anemia, Hereditary, Due to Enzyme Disorder | Anemia Due to Membrane Defect | CDA | Sideroblastic Anemia | Constitutional Aplastic Anemia | Hereditary AnemiaSpain
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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityNot yet recruitingPremenopausal Breast Cancer | Hormone-receptor-positive Breast Cancer | Breast Cancer Patients at Intermediate to High Risk | Ovarian Function Suppression Combined With Aromatase Inhibitor or Tamoxifen or TorimefenChina
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St George's, University of LondonRecruitingChronic Kidney Diseases | Heart Failure With Reduced Ejection Fraction | Hyperkalemia | ACE Inhibitor Induced Hyperkalaemia | Mineralocorticoid Resistant HyperkalemiaUnited Kingdom
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ShireTakeda Development Center Americas, Inc.CompletedAngioedemaUnited States, France, Netherlands, Spain, Hungary, Italy, Canada, Poland, Japan, Germany
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Algemeen Ziekenhuis Maria MiddelaresRecruitingCancer | Atherosclerosis | Cardiotoxicity | Diastolic Dysfunction | Immune Checkpoint Inhibitor-Related Myocarditis | Immune-related Adverse Event | Cardiac Abnormalities, VariableBelgium
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Amsterdam UMC, location VUmcCompletedType 2 Diabetes Mellitus | Diabetic Nephropathy | Diabetic Kidney Disease | Renal Hypoxia | Renoprotection | SGLT2 Inhibitor | ErtugliflozinNetherlands
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Wenjun ChengNot yet recruitingNeoplasms by Histologic Type | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Endocrine System Diseases | Ovarian Diseases | Ovarian Neoplasms | Fallopian Tube Neoplasms | Carcinoma, Ovarian Epithelial | Angiogenesis | Genital Diseases, Female | Antineoplastic... and other conditions
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The Cleveland ClinicRecruitingCardiovascular Diseases | Breast Cancer | Cardiotoxicity | Hematologic Malignancy | Immune Checkpoint Inhibitor-Related MyocarditisUnited States
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Grifols Therapeutics LLCTerminatedCOVID-19United States, Brazil, Chile, Colombia, Mexico
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Catalyst BiosciencesTerminatedFactor VII Deficiency | Hemophilia A With Inhibitor | Glanzmann ThrombastheniaUnited States, India, Italy, Russian Federation, Ukraine
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MacroGenicsRecruitingProstate Cancer Recurrent | Immunotherapy | Androgen-Independent Prostatic Cancer | Androgen-Resistant Prostatic Cancer | Hormone Refractory Prostatic Cancer | Immune Checkpoint Inhibitor | Androgen-Independent Prostatic Neoplasms | Androgen-Insensitive Prostatic Cance | Inhibitory Checkpoint MoleculeUnited States, Spain, France, Belgium, United Kingdom, Poland, Georgia, Bulgaria, Puerto Rico, Australia
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Hospital Universitari Vall d'Hebron Research InstituteHospital Universitario La PazNot yet recruitingHereditary Angioedema With C1 Esterase Inhibitor DeficiencySpain
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University Hospital, CaenCompletedChronic Myeloid Leukemia | Withdrawal Syndrome | Tyrosine Kinase InhibitorFrance
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Masonic Cancer Center, University of MinnesotaRecruitingHurler Syndrome | Sphingolipidoses | Peroxisomal Disorders | Metachromatic Leukodystrophy | Alpha-Mannosidosis | Hunter Syndrome | Mucopolysaccharidosis Disorders | Maroteaux Lamy Syndrome | Sly Syndrome | Fucosidosis | Aspartylglucosaminuria | Glycoprotein Metabolic Disorders | Recessive Leukodystrophies | Globoid... and other conditionsUnited States
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University of CincinnatiChildren's Hospital Medical Center, CincinnatiTerminatedAdrenoleukodystrophy | Zellweger Syndrome | Infantile Refsum's Disease | Bifunctional Enzyme Deficiency
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Lei LiRecruitingEpithelial Ovarian Cancer | Homologous Recombination Deficiency | Homologous Recombination Repair Gene Mutation | Drug Resistance | Overall Survival | Progression-free Survival | Poly(ADP-ribose) Polymerase InhibitorChina
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Indonesia UniversityRecruitingRheumatic Heart Disease | ACE Inhibitor | Mitral Stenosis | Rheumatic Mitral Stenosis | Fibrosis; HeartIndonesia
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Grifols Therapeutics LLCTerminatedType 1 Diabetes MellitusUnited States
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Yonsei UniversityTakedaRecruitingPlatinum-sensitive Recurrent Ovarian Cancer Patients Previously Treated With a PARP InhibitorKorea, Republic of
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T. van der PollZonMw: The Netherlands Organisation for Health Research and Development; Prothya...Terminated
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CENTOGENE GmbH RostockCompletedHereditary Angioedema | Hereditary Angioedema Type I | Hereditary Angioedema Type II | C1 Esterase Inhibitor Deficiency | HAE | Angio Edema | C4 Deficiency | Hereditary Angioedema Type IIITurkey, Armenia, Georgia, India, Peru, Poland, Romania
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Centre Leon BerardCompletedColorectal Cancer | Non Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Epidermal Growth Factor Receptor InhibitorFrance
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Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | EGF-R Positive Non-Small Cell Lung... and other conditionsUnited States, Canada, Taiwan, Korea, Republic of, Singapore, Japan, United Kingdom, France, Netherlands, Spain
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University Health Network, TorontoNovartisCompletedChronic Phase Chronic Myeloid Leukemia | Philadelphia Positive Acute Lymphoblastic Leukemia | Accelerated Phase Chronic Myeloid Leukemia | Blastic Phase Chronic Myeloid Leukemia | Resistant to Tyrosine Kinase Inhibitor TherapyCanada
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Blueprint Medicines CorporationTerminatedNeoplasms | Respiratory Tract Diseases | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | Non Small Cell Lung... and other conditionsUnited States
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NiKang Therapeutics, Inc.RecruitingKidney Cancer | Kidney Neoplasms | Renal Cell Carcinoma | Clear Cell Renal Cell Carcinoma | Hypoxia | Metastatic Renal Cell Carcinoma | Recurrent Renal Cell Carcinoma | Renal Cancer | Advanced Renal Cell Carcinoma | Renal Neoplasms | ccRCC | Refractory Renal Cell Carcinoma | Hypoxia Inducible Factor (HIF) | HIF2α... and other conditionsUnited States
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LMU KlinikumUniversity of Pisa; German Federal Ministry of Education and Research; European...RecruitingMitochondrial Diseases | MDS | Mitochondrial Myopathies | MELAS Syndrome | MIDD | Kearns-Sayre Syndrome | MERRF Syndrome | Barth Syndrome | Leigh Syndrome | MNGIE | LHON | Pearson Syndrome | NARP Syndrome | Coenzyme Q10 Deficiency | SANDO | SCAE | MIRAS | CPEOAustria, Germany, Italy
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Rigshospitalet, DenmarkUnknownCarbohydrate Metabolism, Inborn Errors | Metabolism, Inborn Errors | Lipid Metabolism, Inborn Errors | Glycogen Storage Disease Type II | Glycogen Storage Disease Type V | VLCAD Deficiency | Glycogen Storage Disease Type III | Phosphoglycerate Kinase Deficiency | Neutral Lipid Storage Disease | Carnitine... and other conditionsDenmark
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West Kazakhstan Medical UniversityRecruitingOrnithine Transcarbamylase Deficiency | Biotinidase Deficiency | Citrullinemia | Glutaric Acidemia Type II | Argininosuccinic Aciduria | Maple Syrup Urine Disease | Primary Carnitine Deficiency | Homocystinuria | Carnitine Palmitoyltransferase II Deficiency | Arginase Deficiency | Very Long-chain Acyl-CoA... and other conditionsKazakhstan