Clinical Trials on Intellectual Disability

Total 1545 results

Montefiore Medical Center
Foundation for Prader-Willi Research

Completed

Oxytocin vs. Placebo for the Treatment Hyperphagia in Children and Adolescents With Prader-Willi Syndrome (OXT-PWS)

Hyperphagia | Prader-Willi Syndrome

United States
University of Hartford
Universita di Verona

Terminated

Training Balance Among People With Neurodevelopmental Disabilities (TAPAS)

Cerebral Palsy | Down Syndrome | Autism | Balance | Posture

United States
Boston Children's Hospital
Phelan-McDermid Syndrome Foundation

Completed

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

Intellectual Disability | Autism Spectrum Disorder | Phelan-McDermid Syndrome

United States
Children's Hospital Medical Center, Cincinnati

Completed

An Initial Study of AZD7325 in Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Université de Sherbrooke
FRAXA Research Foundation

Completed

Metformin in Children and Adults With Fragile X Syndrome

Fragile X Syndrome

Canada
Radboud University Medical Center

Completed

The Effect of Bifocals in Children With Down Syndrome

Visual Acuity at Near | Accuracy of Accommodation | Prevention of Strabismus | Task Readiness

Netherlands
Novartis

Completed

Efficacy, Safety and Tolerability of AFQ056 in Fragile X Patients

Fragile X Syndrome

France, Italy, Switzerland
Neuren Pharmaceuticals Limited

Completed

A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Randi J. Hagerman, MD

Completed

Trial of Sertraline to Treat Children With Fragile X Syndrome

Fragile X Syndrome

United States
Indiana University
Indiana Clinical and Translational Sciences Institute

Completed

Riluzole in Fragile X Syndrome

Fragile X Syndrome

United States
Indiana University School of Medicine

Completed

A Prospective Open-label Study of Aripiprazole in Fragile X Syndrome

Fragile X Syndrome

United States
Hoffmann-La Roche

Completed

A Study With RO4917523 in Patients With Fragile X Syndrome

Fragile X Syndrome

United States
Zafgen, Inc.

Completed

An Efficacy, Safety, and Pharmacokinetics Study of Beloranib in Obese Subjects With Prader-Willi Syndrome

Obesity | Prader-Willi Syndrome | Over-weight

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Studying DNA in Samples From Younger Patients With Down Syndrome and Acute Myeloid Leukemia Treated on COG-AAML0431 Clinical Trial

Leukemia
Novartis Pharmaceuticals

Terminated

Long-term, Safety and Tolerability Study of AFQ056 in Adolescent Patients With Fragile X Syndrome (Open-label)

Fragile X Syndrome

United States, Belgium, Australia, Israel, Switzerland, Germany, Denmark, Italy, Netherlands, Spain, Sweden, United Kingdom, France
Stanford University
National Institute of Mental Health (NIMH); Autism Speaks

Completed

Randomized Controlled Study of Donepezil in Fragile X Syndrome

Fragile X Syndrome

United States
Novartis Pharmaceuticals

Terminated

EXPLAIN -FragilE X Registry: An exPlorative Longitudinal Study for chAracterIzation, Treatment Pathways and patieNt-related Outcomes (EXPLAIN)

Fragile-X Syndrome

Germany
FRAXA Research Foundation
Fragile X Research Foundation of Canada

Completed

Add-on Pilot Trial of Minocycline to Treat Fragile X Syndrome

Fragile X Syndrome

Canada
Novartis Pharmaceuticals

Completed

Safety and Efficacy of AFQ056 in Adolescent Patients With Fragile X Syndrome

Fragile X Syndrome

United States, Belgium, Australia, Israel, Switzerland, Germany, France, Canada, Denmark, Indonesia, Italy, Netherlands, Spain, Sweden, Turkey, United Kingdom
Seaside Therapeutics, Inc.

Completed

Biomarker Testing and DNA Collection in Subjects Participating in Protocol 22001

Fragile X Syndrome

United States
Seaside Therapeutics, Inc.

Completed

Efficacy and Safety Study of STX209 (Arbaclofen) for Social Withdrawal in Adolescents and Adults With Fragile X Syndrome (Harbor-A)

Fragile X Syndrome

United States
Seaside Therapeutics, Inc.

Terminated

An Open Label Extension Study in Subjects With Fragile X Syndrome (209FX303)

Fragile X Syndrome

United States
Seaside Therapeutics, Inc.

Suspended

A Study to Assess the Tolerability of a Single Dose of STX107 in Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Neuropharm

Completed

Open Label Study Investigating Safety and Efficacy of NPL2009 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance Tasks, Adults With Fragile X Syndrome

Fragile X Syndrome

United States
Aarhus University Hospital

Completed

The Intestinal Function in People With Prader-Willi Syndrome

Constipation | Prader-Willi Syndrome | Incontinence

Denmark
Samsung Medical Center

Completed

Characterization of Transcriptional Regulators of Ghrelin Hormone Which Causes Genetic Obesity

Obesity | Prader Willi Syndrome
University of British Columbia

Terminated

Prader-Willi Syndrome and Appetite

Hyperphagia | Prader-Willi Syndrome

Canada
University of Manitoba
Rehabilitation Centre for Children, Canada

Not yet recruiting

Technology in Play for Children With Physical Disabilities: the Dice Model of Play

Physical Disability
Tung Wah College
Chinese University of Hong Kong; Pok Oi Hospital; Golden Age Foundation

Not yet recruiting

Virtual Reality for Mental Well-being in Older People With Physical Disabilities

Mental Health Wellness 1 | Physical Disability
Universitaire Ziekenhuizen KU Leuven
KU Leuven; UHasselt

Completed

Delphi Study on Rehabilitation Following Lumbar Arthrodesis

Surgery | Physical Disability | Lumbar Spine Degeneration

Belgium
Bionano Genomics
Columbia University; University of Iowa; Medical College of Wisconsin; Augusta... and other collaborators

Recruiting

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

Intellectual Disability | Autism Spectrum Disorder | Fragile X Syndrome | Developmental Disability | Congenital Anomaly | Facioscapulohumeral Muscular Dystrophy 1

United States
Université de Sherbrooke
Canadian Institutes of Health Research (CIHR); Centre de recherche du Centre... and other collaborators

Not yet recruiting

Effect of CBD on the Brain

Fragile X Syndrome
Children's Hospital of Fudan University

Recruiting

The Intervention of Obesity in Children With Prader-Willi Syndrome Using Prebiotics and Probiotics

Prader-Willi Syndrome

China
University of Southern California
National Institute on Aging (NIA); Alzheimer's Therapeutic Research Institute; Alzheimer's Clinical Trials Consortium

Recruiting

Trial-Ready Cohort-Down Syndrome (TRC-DS) (TRC-DS)

Dementia | Alzheimer Disease | Down Syndrome

United States, Spain, United Kingdom
Icahn School of Medicine at Mount Sinai

Recruiting

DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.

Autism Spectrum Disorder | DDX3X | Mental Retardation, X-linked 102

United States
National Institute of Mental Health (NIMH)

Recruiting

Defining the Brain Phenotype of Children With Williams Syndrome

Williams Syndrome | Duplication

United States
Saniona

Completed

Co-administration of Tesofensine/Metoprolol in Subjects With Prader-Willi Syndrome (PWS) (2016-003694-18)

Confirmed Genetic Diagnosis of Prader-Willi Syndrome

Czechia, Hungary
Weill Medical College of Cornell University
National Institutes of Health (NIH); PWSAUSA

Terminated

Effect of Rimonabant on Weight Gain and Body Composition in Adults With Prader Willi Syndrome (PWS)

Prader-willi Syndrome

United States
Sheba Medical Center
Tel Aviv University

Enrolling by invitation

Motor Deficits and Signal Conduction in Individuals With Williams Syndrome

Williams Syndrome

Israel
Stanford University
The John Merck Fund

Completed

Treatment of Disruptive Behaviors in Fragile X Syndrome

Fragile X Syndrome | Disruptive Behavior

United States
Baylor College of Medicine

Completed

The Role of Dietary Calcium for the Treatment of Osteopenia in Girls With Rett Syndrome

Rett Syndrome
Atılım University

Completed

Investigation of Cardiopulmonary Parameters, Motor Development and Muscle Strength in DS With and Without CHD

Down Syndrome | Gross Motor Development Delay | Congenital Heart Defects

Turkey
Riphah International University

Completed

Efficacy of AAC for Functional Communication

Cerebral Palsy | Down Syndrome | Learning Disabilities

Pakistan
NYU Langone Health
Winthrop University Hospital

Withdrawn

Dose Clinical Trial of Guanfacine Extended Release for the Reduction of Aggression and Self-injuries Behavior Associated With Prader-Willi Syndrome

Prader-Willi Syndrome

United States
Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical...

Unknown

Autonomic Regulation in Prader-Willi Syndrome

Autonomic Dysfunction

Taiwan
Stanford University

Completed

Teaching Math Skills to Individuals With Fragile X Syndrome

Developmental Disabilities | Fragile X Syndrome

United States
Kingkaew Pajareya
Mahidol University

Completed

DIR/ Floortime™ Parent Training Intervention for the Children With Developmental Disabilities (RCT/DD)

Cerebral Palsy | Down's Syndrome | Delayed Development

Thailand
Massachusetts General Hospital

Completed

Fat Distribution and Glucose Metabolism in Williams Syndrome

Williams Syndrome

United States
Ferring Pharmaceuticals

Completed

Treatment of Hyperphagia Behavioral Symptoms in Children and Adults Diagnosed With Prader-Willi Syndrome

Hyperphagia in Prader-Willi Syndrome

United States
University of Florida
Foundation for Prader-Willi Research

Completed

Hypoglycemia in Prader-Willi Syndrome

Hypoglycemia | Prader Willi Syndrome

United States

Clinical Trials on Intellectual Disability

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