Clinical Trials on Intermittent Hypoxemia

Total 1684 results

University of Calgary
Alberta Health services

Completed

Treatment of Hypoxemic Respiratory Failure and ARDS With Protection, Paralysis, and Proning (TheraPPP) Pathway (TheraPPP)

Acute Respiratory Distress Syndrome | ARDS, Human | Hypoxemic Respiratory Failure

Canada
University of Chicago

Completed

Studies to Determine Whether Oxygen Sensing is Impaired in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infected Patients

Hypoxia | SARS-CoV-2 Acute Respiratory Disease | Carotid Bodies

United States
Zonguldak Bulent Ecevit University

Completed

Relationship Between STOP BANG Score and Airway Management

Hypoxia | Obstructive Sleep Apnea | Airway Obstruction

Turkey
University of Miami

Completed

Effects of Intermittent Hypoxia (IH) on Metabolism and Dysglycemia, in Overweight/Obese Persons SCI

Obesity | Insulin Resistance | Spinal Cord Injuries

United States
University Hospital, Grenoble
Institut National de la Santé Et de la Recherche Médicale, France

Terminated

Intermittent Hypoxia 2: Cardiovascular and Metabolism (IH2)

Hypoxia | Obstructive Sleep Apnea | Sleep Apnea

France
RenJi Hospital
Shanghai Tongji Hospital, Tongji University School of Medicine; Shanghai Pudong...

Unknown

WEI NASAL JET for The Sedation of Outpatient Upper Gastrointestinal Endoscopy

Hypoxia | Gastric Cancer | Peptic Ulcer | Esophagus Cancer | Oesophagitis

China
University of Utah
National Heart, Lung, and Blood Institute (NHLBI); Primary Children's Hospital

Recruiting

Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior

Hypoxia | Neurodevelopmental Disorders | Congenital Heart Disease in Children | Complex Congenital Heart Disease

United States
RenJi Hospital
Second Affiliated Hospital of Soochow University; Dushu Lake Hospital Affiliated...

Not yet recruiting

HFNO Combined With NPA Reduces Hypoxia During Sedated Gastrointestinal Endoscopy In Obese Patients

Gastric Cancer | Intestinal Polyps | Gastric Ulcer | Intestinal Cancer

China
Clinical Hospital Center Rijeka

Not yet recruiting

Immunometabolic Pattern of Intermittent Hypoxia During ST-segment Elevation Myocardial Infarction

Myocardial Ischemic-reperfusion Injury
University Health Network, Toronto
Canadian Cancer Trials Group; Princess Margaret Hospital, Canada

Active, not recruiting

Cervix:Hypoxia, Interstitial Fluid Pressure and GSH Levels

Cervix Neoplasms

Canada
Mallinckrodt

Withdrawn

Inhaled Nitric Oxide (INO) In Hypoxic Respiratory Failure

Hypoxic Respiratory Failure With Pulmonary Hypertension
Maastricht Radiation Oncology
Maastricht University Medical Center

Withdrawn

Hypoxia-guided Radiotherapy With Cisplatin-etoposide in Stage I-III : Small Cell Lung Cancer(SCLC) (HX4 in SCLC)

Small Cell Lung Cancer (SCLC)
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Recruiting

Milrinone in Congenital Diaphragmatic Hernia

Persistent Pulmonary Hypertension of the Newborn | Congenital Diaphragmatic Hernia | Hypoxemic Respiratory Failure | Pulmonary Hypoplasia

United States
Washington University School of Medicine

Completed

Smell in Covid-19 and Efficacy of Nasal Theophylline (SCENT2)

Covid19 | Anosmia | SARS-CoV-2 Infection | Olfactory Disorder | Ageusia | Covid-19 Pandemic | Hyposmia | Hypogeusia

United States
Washington University School of Medicine

Completed

Visual-OLfactory Training in Participants With COVID-19 Resultant Loss of Smell (VOLT)

Covid19 | Anosmia | SARS-CoV-2 Infection | COVID-19 Pandemic | Ageusia | Hyposmia | Hypogeusia

United States
KU Leuven
Research Foundation Flanders; National Institute for Health and Disability...

Completed

Optimising Diagnosis and Antibiotic Prescribing for Acutely Ill Children in Primary Care (ERNIE2)

Pneumonia | Sepsis | Abscess | Cellulitis | Meningitis | Osteomyelitis | Complicated Urinary Tract Infection | Bacteraemia | Gastro-enteritis With Dehydration | Viral Respiratory Infection Complicated With Hypoxia

Belgium
Washington University School of Medicine

Completed

Stellate Ganglion Block for COVID-19-Induced Olfactory Dysfunction

Anosmia | Olfactory Disorder | Parosmia | Hyposmia

United States
Elias Manjarrez
National Council of Science and Technology, Mexico

Active, not recruiting

Low-field Thoracic Magnetic Stimulation Increases Peripheral Oxygen Saturation Levels in COVID-19 Patients

COVID-19 | Oxygen Deficiency | Acute Respiratory Failure

Mexico
University of Aarhus

Completed

Diameter Changes of Retinal Vessels During Hypoxia

Diabetic Maculopathy | Diabetes Mellitus Type 1

Denmark
Medical University of Vienna

Unknown

Molecular Adsorbent Recirculating System (MARS®) in Hypoxic Hepatitis (MARS in HH)

Acute Liver Failure | Hypoxic Hepatitis | Ischemic Hepatitis | Shock Liver | Hypoxic Liver Injury

Germany, Austria
The Royal Wolverhampton Hospitals NHS Trust
University of Wolverhampton

Recruiting

Zn-DDC to Target Hypoxia-NFkappaB-CSCs Pathway in Multiple Myeloma

Multiple Myeloma

United Kingdom
Malin Jonsson Fagerlund

Completed

Effect of Rocuronium on the Acute Hypoxic Ventilatory Response in Patients With Obstructive Sleep Apnea

OSA | Neuromuscular Blockade | Rocuronium | Hypoxic Ventilatory Response | CPAP

Sweden
Radboud University Medical Center
Dutch Cancer Society

Completed

Patient Selection for Hypoxia Modifying Treatments in Larynx Carcinomas

Larynx Cancer

Netherlands
University of Calgary

Completed

Effect of Selective and Nonselective Cyclooxygenase Enzyme Inhibition on Arterial Blood Pressure and Cerebral Blood Flow With Exposure to Intermittent Hypoxia in Humans

Cardiovascular Diseases | Stroke | Hypertension | Obstructive Sleep Apnea

Canada
Hôpital Louis Mourier

Completed

Weaning From Nasal High Flow Therapy

Acute Respiratory Distress Syndrome | Respiratory Distress Syndrome, Adult | Weaning Failure | Acute Hypoxemic Respiratory Failure

France
Peking Union Medical College Hospital

Not yet recruiting

Chemoradiotherapy With or Without Metformin in Locally Advanced Cervical Cancer

Cervical Cancer | Hypoxia | Radiotherapy | Metformin | PET/CT
RenJi Hospital
Shanghai Tongji Hospital, Tongji University School of Medicine; Shanghai Oriental...

Recruiting

High-flow Nasal Cannula Oxygenation Decrease Hypoxia in Sedated Gastrointestinal Endoscopes in Obesity

Hypoxia | Gastric Cancer | Polyp of Colon | Colon Cancer | Esophagus Cancer

China
Danish Head and Neck Cancer Group

Recruiting

DAHANCA 30: A Randomized Non-inferiority Trial of Hypoxia-profile Guided Hypoxic Modification of Radiotherapy of HNSCC. (DAHANCA30)

Hypoxia | Head and Neck Squamous Cell Carcinoma | Radiotherapy | Hypoxic Modification | Gene Profile, Gene Signature

Denmark
Direct Biologics, LLC

Available

Expanded Access for Use of bmMSC-Derived Extracellular Vesicles in Patients With COVID-19 Associated ARDS

Hypoxia | Covid19 | ARDS | Cytokine Storm
Hunter Holmes Mcguire Veteran Affairs Medical Center
McGuire Research Institute

Completed

Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation (AVoCaDO)

COVID-19 | Hypoxia

United States
University of British Columbia

Completed

AT1R Blockade and Periodic Breathing During Sleep in Hypoxia

Hypoxia | Sleep Disordered Breathing | Respiration; Sleep Disorder | Chemoreceptor Apnea

Canada
University of California, Los Angeles

Completed

Non-invasive Intervention for Apnea of Prematurity

Hypoxia | Bradycardia | Apnea of Prematurity

United States
Brigham and Women's Hospital

Unknown

Evaluation of Abdominal Tissue Oxygenation in Premature Infants Using Near Infrared Spectroscopy

Hypoxia | Infant, Premature, Diseases | Necrotizing Enterocolitis

United States
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development...

Withdrawn

Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure (IPGE1)

Streptococcal Infections | Respiratory Insufficiency | Pulmonary Hypertension | Respiratory Distress Syndrome, Newborn | Infant, Newborn

United States
Shirley Ryan AbilityLab
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Not yet recruiting

Intermittent Hypoxia in Persons With Multiple Sclerosis

Multiple Sclerosis | Multiple Sclerosis, Secondary Progressive | Multiple Sclerosis-Relapsing-Remitting

United States
Qianfoshan Hospital

Recruiting

Novel Biomarkers of Hypoxia and Metabolism in Clear Cell Renal Cell Carcinoma

Clear Cell Renal Cell Carcinoma

China
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); National Institutes of Health (NIH)

Active, not recruiting

Prognostic Value of Tumor Hypoxia, as Measured by 18F-FMISO Breath Hold PET/CT, in Non-Small-Cell-Lung Cancer (NSCLC) Patients

Non-Small-Cell-Lung Cancer (NSCLC)

United States
Centre Henri Becquerel

Completed

Comparative Study of the Hypoxia Measured in FAZA and F-miso PET/CT Scan in Patients With Non-small Cell Lung Cancer (RTEP6)

Non-small Cell Lung Cancer

France
Taipei Veterans General Hospital, Taiwan

Unknown

Impact of Intermittent Hypoxia on the Function of the Phagocytes

Obstructive Sleep Apnea of Adult

Taiwan
Hua Yan

Completed

Hypoxic Preconditioning on Patients

Carotid Artery Stenosis | Ischemic Cerebrovascular Disease | Hypoxic Preconditioning

China
Massachusetts General Hospital

Completed

Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study)

Pneumonia | Hypoxia | Respiratory Failure | Acute Kidney Injury | Pulmonary Edema | Acute Respiratory Failure Requiring Reintubation

United States
Xuzhou Medical University
University of North Carolina, Chapel Hill

Unknown

Hypoxia Imaging -Guided Radiotherapy of Nasopharyngeal Carcinoma

Nasopharyngeal Carcinoma
Abramson Cancer Center of the University of Pennsylvania

Completed

Fluorine F18-EF5 and Fludeoxyglucose F18 Positron Emission Tomography in Assessing Hypoxia and Glycolysis in Patients With Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer

Non-small Cell Lung Cancer

United States
British Columbia Cancer Agency
Carraressi Foundation OVCARE

Terminated

Imaging Tumor Hypoxia With 18F-EF5 PET in Recurrent or Metastatic Clear Cell Ovarian Cancer

Ovarian Neoplasms | Ovarian Cancer

Canada
Mayo Clinic
University of Alabama at Birmingham; University of Mississippi Medical Center

Completed

Hypoxia and Inflammatory Injury in Human Renovascular Hypertension

Chronic Kidney Disease | Renal Artery Stenosis | Ischemic Nephropathy | Renovascular Disease

United States
Stem Cell and Cancer Research Indonesia
Provincial Government of Central Java, Indonesia

Recruiting

Treatment of Severe COVID-19 Patients Using Secretome of Hypoxia-Mesenchymal Stem Cells in Indonesia

Covid-19 | Cytokine Storm

Indonesia
University of Florida

Completed

Acute Intermittent Hypoxia and Breathing in Neuromuscular Disease (AIH in ALS)

Neuromuscular Diseases | Amyotrophic Lateral Sclerosis (ALS)

United States
Royal Devon and Exeter NHS Foundation Trust
University of Exeter

Completed

Obstructive Sleep Apnoea and Adipose Tissue Dysfunction

Obesity | Hypoxia | Obstructive Sleep Apnoea

United Kingdom
University of Alabama at Birmingham

Completed

Prolonged Prone Positioning for COVID-19-induced Acute Respiratory Distress Syndrome (ARDS)

Covid19 | ARDS | Acute Hypoxemic Respiratory Failure

United States
Alexandria University

Recruiting

Effect of Low Doses of Hypoxia-inducible Factor- Prolyl Hydroxylase Enzyme Inhibitor Plus Iron in the Treatment of Anemia in Dialysis-dependent Chronic Kidney Disease Patients

Anemia in Dialysis-dependent CKD Patients

Egypt

Clinical Trials on Intermittent Hypoxemia

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