Clinical Trials on Intrahepatic Cholangiocarcinoma

Total 1030 results

Arena Pharmaceuticals

Terminated

Safety, Tolerability, and Efficacy of Etrasimod (APD334) in Participants With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States, Australia, New Zealand
Intercept Pharmaceuticals

Completed

Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis (POISE)

Primary Biliary Cirrhosis

United States, Spain, United Kingdom, Austria, Netherlands, Australia, Italy, Germany, Poland, Sweden, France, Canada, Belgium
Gilead Sciences

Terminated

Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis (PBC-Phase 2)

Primary Biliary Cholangitis

United States, Canada, Austria, United Kingdom
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Unknown

A Study of TQA3526 in the Treatment of Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

China
Biocad

Terminated

Non-comparative Study of BCD-085 in Combination With UDCA in Patients With Primary Biliary Cholangitis

Liver Cirrhosis, Biliary

Russian Federation
Mirum Pharmaceuticals, Inc.

Withdrawn

An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis (CASCADE)

Primary Biliary Cirrhosis

United States, United Kingdom
SAMEY
Axonal-Biostatem

Unknown

A Post-Authorisation Non-Interventional Observational of Patients in France With Primary Biliary Cholangitis Treated With Obeticholic Acid in Real Life (OCARELIFE)

Primary Biliary Cholangitis

France
NGM Biopharmaceuticals, Inc
NGM Biopharmaceuticals Australia Pty Ltd

Completed

Phase 2b Study of NGM282 Extended Treatment in Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States, Australia, New Zealand
Xijing Hospital of Digestive Diseases

Unknown

Fuzhenghuayu in Combination With Ursodeoxycholic Acid in Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

China
Fast Forward Pharmaceuticals

Unknown

Pilot Study of FFP104 Dose Escalation in PBC Subjects

Primary Biliary Cirrhosis

Netherlands, United Kingdom
Instituto Nacional de Ciencias Medicas y Nutricion...

Completed

High-protein High-fiber Diet in Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

Mexico
Light Chain Bioscience - Novimmune SA

Terminated

Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody (PIANO)

Primary Biliary Cirrhosis

Italy, United Kingdom
Mayo Clinic
UCB Pharma

Completed

Moexipril for Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Pharmacokinetic Study Of Tigecycline In Adult Subjects With Primary Biliary Cirrhosis

Liver Cirrhosis, Biliary

United States, Puerto Rico
Washington University School of Medicine

Terminated

Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma

Liver Neoplasms | Cholangiocarcinoma

United States
Stanford University
The University of Texas Health Science Center, Houston; University of Rochester

Terminated

Comparison Bile Duct Brushings, Cholangioscopy-Directed Biopsies and Pediatric Forceps Biopsies in Biliary Strictures

Cholangiocarcinoma | Stricture; Bile Duct

United States
Intercept Pharmaceuticals

Terminated

Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis (COBALT)

Liver Cirrhosis, Biliary

United States, Spain, Korea, Republic of, Australia, Finland, Israel, Lithuania, United Kingdom, Belgium, Netherlands, Estonia, Brazil, Italy, Serbia, Sweden, Argentina, Austria, Canada, Chile, Denmark, France, Germany, Hong Kong, Hun... and more
Intercept Pharmaceuticals

Terminated

Study of Obeticholic Acid (OCA) Evaluating Pharmacokinetics and Safety in Participants With Primary Biliary Cholangitis (PBC) and Hepatic Impairment

Liver Cirrhosis, Biliary

United States, Argentina, Spain, Belgium, Germany, Canada, Australia, Estonia, Brazil, Hungary, Italy, Lithuania
Mayo Clinic
American College of Gastroenterology

Completed

Modafinil in the Treatment of Fatigue in Patients With Primary Biliary Cirrhosis (PBC) (PBC)

Fatigue | Primary Biliary Cirrhosis

United States
University of Alberta
GlaxoSmithKline; Axcan Pharma

Completed

Study of Combivir for Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States, Canada, United Kingdom
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Effects on Quality of Life With Zinc Supplementation in Patients With Gastrointestinal Cancer

Gastric Carcinoma | Unresectable Pancreatic Carcinoma | Liver and Intrahepatic Bile Duct Carcinoma | Unresectable Esophageal Carcinoma

United States
University of Leipzig
Hannover Medical School; RWTH Aachen University; Academisch Medisch Centrum -... and other collaborators

Recruiting

Prospective, Multicenter Cohort Study on Primary Biliary Cholangitis (PBC-Cohort)

Primary Biliary Cholangitis | PBC

Germany
National Scientific Medical Center, Kazakhstan
Eurasia Invest Ltd.; Ministry of Education and Science, Republic of Kazakhstan

Completed

Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary Cholangitis

Primary Biliary Cirrhosis

Kazakhstan
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom; Department of Health, United Kingdom

Completed

B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis (RITPBC)

Fatigue | Primary Biliary Cirrhosis

United Kingdom
Yilihamu·Abilitifu

Completed

The Effectiveness of Combining Ursodeoxycholic Acid With Vitamin D in Treating Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
Mirum Pharmaceuticals, Inc.

Completed

Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary Cirrhosis (CLARITY)

Primary Biliary Cirrhosis | PBC

United States, United Kingdom, Canada
University of Aarhus
Danish Cancer Society

Completed

Changes in Liver Function After Stereotactic Body Radiation Therapy Measured by PET/CT

Hepatocellular Carcinoma | Cholangiocarcinoma | Metastases | Stereotactic Body Radiotherapy

Denmark
The Second Hospital of Nanjing Medical University

Unknown

Endoscopic Biliary RFA of Malignant Bile Duct Obstruction

Cholangiocarcinoma | Bile Duct Obstruction

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

Study of Obeticholic Acid（OCA） Combination With Ursodeoxycholic Acid (UDCA) in Patients With Primay Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

China
Calliditas Therapeutics Suisse SA

Active, not recruiting

A Trial of Setanaxib in Patients With Primary Biliary Cholangitis (PBC) and Liver Stiffness (TRANSFORM)

Primary Biliary Cholangitis | Liver Stiffness

United States, Spain, France, Australia, Israel, Canada, Switzerland, Italy, New Zealand, Germany, Poland, Greece, United Kingdom, Belgium, Austria, Czechia, Hungary, Sweden
National Institute of Diabetes and Digestive and...

Terminated

SAMe to Treat Biliary Cirrhosis Symptoms

Liver Cirrhosis, Biliary

United States
Shanghai Zhongshan Hospital

Unknown

Process Optimization of Preoperative Biliary Drainage in Patients With Malignant Obstructive Jaundice

Klatskin Tumor | Jaundice, Obstructive
University Hospital Dresden

Completed

Efficacy of Imatinib and 5-FU/Leucovorin in Patients With Advanced Carcinoma of the Gallbladder and Bile Duct

Advanced or Metastatic Cholangiocellular Carcinoma and Bile Duct

Germany
University of Birmingham
University Hospital Birmingham NHS Foundation Trust; Intercept Pharmaceuticals

Terminated

EXerCise Intervention in cholesTatic LivEr Disease: The EXCITED Study (EXCITED)

Primary Biliary Cholangitis

United Kingdom
University of Sao Paulo General Hospital

Completed

Development of Ursodeoxycholic Acid 300 mg at Hospital Das Clinicas of the University of São Paulo School of Medicine

Primary Biliary Cirrhosis | Ursodeoxycholic Acid

Brazil
Bold Therapeutics, Inc.

Active, not recruiting

BOLD-100 in Combination With FOLFOX for the Treatment of Advanced Solid Tumours

Colorectal Cancer | Pancreatic Cancer | Cholangiocarcinoma | Gastric Cancers

Korea, Republic of, United States, Canada
University of Aarhus
Aarhus University Hospital; Hvidovre University Hospital

Recruiting

Bezafibrate in Patients With Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

Denmark
CymaBay Therapeutics, Inc.

Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

United States, Korea, Republic of, Belgium, Spain, France, Switzerland, Romania, United Kingdom, Austria, Israel, Australia, Argentina, Canada, Chile, Germany, Greece, Hungary, Italy, Mexico, Netherlands, Poland, Czechia, New Zealand, Turke... and more
Target PharmaSolutions, Inc.

Active, not recruiting

A 5-year Longitudinal Observational Study of Patients With Primary Biliary Cholangitis

Biliary Cirrhosis, Primary

United States
West China Hospital

Unknown

Ursodeoxycholic Acid Combined With Total Glucosides of Paeony in the Treatment of PBC With AIH Features 1

Hepatitis | Autoimmune | Primary Biliary Cholangitis

China
Xiaoli Fan

Completed

Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China Hospital

Liver Diseases | Liver Cirrhosis | Cholangitis | Bile Duct Diseases | Cholestasis | Liver Cirrhosis, Biliary

China
Rigshospitalet, Denmark

Recruiting

Open Versus Laparoscopic Ablation of Liver Malignancies (OPTIMAL)

Hepatocellular Carcinoma | Cholangiocarcinoma | Liver Metastases

Denmark
Karolinska University Hospital

Completed

Surveillance Study for Early Detection of Cholangiocarcinoma (CCA) in Primary Sclerosing Cholangitis (PSC) (PSC)

Cholangiocarcinoma | Primary Sclerosing Cholangitis

Sweden
Ipsen

Active, not recruiting

Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) (ELATIVE)

Primary Biliary Cirrhosis

United States, France, Spain, Belgium, Germany, Switzerland, Brazil, United Kingdom, Argentina, Canada, Chile, Italy, South Africa, Turkey
Instituto Mexicano del Seguro Social

Active, not recruiting

A Study to Assess Efficacy and Safety of Bezafibrate in Patients With Primary Biliary Cholangitis

Primary Biliary Cirrhosis

Mexico
National Institute of Diabetes and Digestive and...
Mayo Clinic

Completed

Pilot Study of Budesonide for Patients With Primary Sclerosing Cholangitis

Cholangitis, Sclerosing | Liver Cirrhosis, Biliary

United States
The University of Texas Medical Branch, Galveston
National Cancer Institute (NCI)

Terminated

Vaccine Therapy in Treating Patients With Cancer of the Gastrointestinal Tract

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Intestine Cancer | Gallbladder Cancer | Extrahepatic Bile Duct Cancer

United States
Medical University of South Carolina
Boston University; Johns Hopkins University; Fox Chase Cancer Center; Washington... and other collaborators

Terminated

A Trial of Percutaneous vs. Endoscopic Drainage of Suspected Klatskin Tumors (INTERCPT)

Cholangiocarcinoma | Hilar Lymphadenopathy | Biliary Stricture

United States
Zydus Therapeutics Inc.

Completed

Study to Evaluate Safety, Tolerability and Efficacy of Saroglitazar Mg in Patients With Primary Biliary Cholangitis (EPICS)

Primary Biliary Cirrhosis

United States
CymaBay Therapeutics, Inc.

Completed

Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

United States, Germany, United Kingdom, Canada

Clinical Trials on Intrahepatic Cholangiocarcinoma

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