Clinical Trials on Intraoperative Hypotension in South Africa

Total 479 results

Eli Lilly and Company

Completed

A Study of LY2623091 in Participants With High Blood Pressure

Primary Hypertension

United States, Puerto Rico, Canada
VA Office of Research and Development
Corporal Michael J. Crescenz VA Medical Center; VA Boston Healthcare System; Ralph...

Completed

Unmet Social Needs Study

Hypertension | Cardiovascular Disease | Diabetes Mellitus | Hyperlipidemia

United States
Takeda

Completed

Safety and Tolerability of Azilsartan Medoxomil Plus Chlorthalidone Compared to Olmesartan Medoxomil Plus Hydrochlorothiazide in Participants With Essential Hypertension

Essential Hypertension

Netherlands, Austria, Germany, Poland, United Kingdom
Bayer
Xcenda, LLC

Active, not recruiting

A Study to Learn About How Well Riociguat Works, How Safe it is and How it is Used Under Real World Conditions in Patients in the United States Who Are Receiving Riociguat for High Blood Pressure in the Arteries That Carry Blood From the Heart to the Lungs (Pulmonary Arterial Hypertension, PAH) (ROAR)

Pulmonary Arterial Hypertension

United States, Puerto Rico
New World Medical, Inc.

Recruiting

STREAMLINE®SURGICAL SYSTEM Compared to iStent Inject W® in Patients With Open-Angle Glaucoma (VENICE)

Open Angle Glaucoma

United States, Costa Rica
Actelion
Canadian Heart Research Centre

Completed

Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program (PAH QuERI Ext)

Pulmonary Arterial Hypertension

United States, Puerto Rico
Merck Sharp & Dohme LLC

Recruiting

Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008) (MOONBEAM)

Pulmonary Arterial Hypertension

Germany, United States, Poland, Spain, Colombia, France, Turkey, Israel, Australia, United Kingdom, Netherlands
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children With Pulmonary Arterial Hypertension.

Pulmonary Arterial Hypertension, Children

United States, Taiwan, Guatemala, Russian Federation, Japan, Chile, Colombia, Canada, Italy, Hungary, Poland, Peru, Sweden, Brazil, India, Malaysia, Mexico
Allergan

Completed

Safety and Effectiveness of the XEN45 Glaucoma Treatment System in Patients With Angle Closure Glaucoma

Glaucoma | Angle-Closure

Australia, Canada, Korea, Republic of, Singapore, Taiwan, United Kingdom
Elpen Pharmaceutical Co. Inc.

Completed

Eplerenone in Heart Failure Treatment (INOSET)

Heart Failure | Hypertension | Acute Myocardial Infarction

Greece
Medical University of South Carolina
Agency for Healthcare Research and Quality (AHRQ)

Completed

Pharmacy Interventions to Improve Chronic Disease Medication Refill

Depression | Heart Diseases | Hypertension | Diabetes | Hyperlipidemia | Psychoses

United States
Pulmonary Hypertension Association, Inc.
University of Washington, the Collaborative Health Studies Coordinating Center

Recruiting

Pulmonary Hypertension Association Registry (PHAR)

Pulmonary Arterial Hypertension | Pulmonary Hypertension | Chronic Thromboembolic Pulmonary Hypertension

United States
Novartis

Completed

Study of the Efficacy and Safety of Aliskiren HCTZ vs Ramipril in Obese Patients (BMI ≥ 30) With Stage 2 Hypertension (ATTAIN)

Hypertension

United States
Allergan

Completed

Efficacy and Safety of Bimatoprost Sustained-Release (SR) in Patients With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-Angle

United States, Singapore, Italy, United Kingdom, Egypt, Korea, Republic of, Argentina, Canada, Colombia, Czechia, Germany, Malaysia, New Zealand, South Africa, Turkey
Aerie Pharmaceuticals

Completed

Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting

Ocular Hypertension | Glaucoma, Open-Angle

United States
Actelion

Terminated

Iloprost Power Disc-15 in Pulmonary Arterial Hypertension (INHALE-15)

Pulmonary Arterial Hypertension

United States
Actelion

Terminated

The "VISION" Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial Hypertension (VISION)

Pulmonary Hypertension

United States
Santen Inc.

Completed

Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension (ANGEL-2)

Primary Open Angle Glaucoma | Ocular Hypertension

United States
United Therapeutics
Lung Biotechnology PBC

Recruiting

A Study of a Mean Pulmonary Artery Pressure-Targeted Approach With Early and Rapid Treprostinil Therapy to Reverse Right Ventricular Remodeling in Participants With Pulmonary Arterial Hypertension (ARTISAN)

Pulmonary Arterial Hypertension

United States
GB002, Inc.

Recruiting

Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)

Pulmonary Arterial Hypertension

United States, Spain, Israel, Korea, Republic of, Netherlands, France, Singapore, United Kingdom, Lithuania, Australia, Latvia, Argentina, Portugal, Greece, Czechia, Puerto Rico, Belgium, Italy, Poland, Romania, Serbia, Austria, Chile, Denma... and more
Pfizer

Completed

A 6 Month Study Comparing Latanoprost With Timolol in Patients With Open Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma | Open Angle Glaucoma

United States
Forest Laboratories

Completed

Study of the Efficacy and Safety of the Combination of Two FDA Approved Oral Medications, Nebivolol and Valsartan for Treatment of Stage 1 or 2 Hypertension

Stage 2 Hypertension | Stage 1 Hypertension

United States
Glaukos Corporation

Completed

GTS400 Stent Implantation in Conjunction With Cataract Surgery in Subjects With Open-angle Glaucoma

Glaucoma

United States
New World Medical, Inc.

Completed

A First in Human Clinical Trial to Evaluate the Safety and Effectiveness of the STREAMLINE SURGICAL SYSTEM in Patients With Open-Angle Glaucoma

Open Angle Glaucoma

Mexico, Costa Rica, Dominican Republic
United Therapeutics

Active, not recruiting

ADAPT - A Patient Registry of the Real-world Use of Orenitram® (ADAPT)

Pulmonary Arterial Hypertension

United States
La Jolla Pharmaceutical Company

Completed

A Phase 3 Study of LJPC-501 in Patients With Catecholamine-Resistant Hypotension (ATHOS-3)

Sepsis | Catecholamine-resistant Hypotension (CRH) | Distributive Shock | High Output Shock

United States, Canada, Belgium, Australia, United Kingdom, Finland, New Zealand, France, Switzerland, Germany
VA Office of Research and Development
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Financial Incentives to Translate ALLHAT Into Practice: A Randomized Trial

Hypertension

United States
Boehringer Ingelheim

Completed

A Comparison of Telmisartan + Hydrochlorothiazide With Amlodipine + Hydrochlorothiazide in the Control of Blood Pressure in Older Patients With Predominantly Systolic Hypertension (ATHOS Study)

Hypertension

Italy, Germany, Netherlands, France, South Africa, Belgium, Denmark, Finland, Ireland, Spain
Novartis Pharmaceuticals

Completed

Efficacy, Tolerability and Safety of RKI983 (0.05% & 0.10%) vs Xalatan in Patients With POAG or Ocular Hypertension

Ocular Hypertension | Glaucoma

United States
Gilead Sciences

Completed

ARIES - Ambrisentan in Patients With Moderate to Severe Pulmonary Arterial Hypertension (PAH)

Pulmonary Hypertension

United States, Australia, Canada
Actelion

Completed

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension (SERAPHIN)

Pulmonary Arterial Hypertension

United States, United Kingdom, Belarus, Argentina, Australia, Austria, Belgium, Bulgaria, Canada, Chile, China, Colombia, Croatia, France, Germany, Hong Kong, Hungary, India, Israel, Italy, Malaysia, Mexico, Netherlands, Norway, Peru, Poland and more
New World Medical, Inc.

Not yet recruiting

Clinical Trial to Evaluate the Safety and Effectiveness of a Canaloplasty Device in Subjects With Open-Angle Glaucoma

POAG

Costa Rica, Honduras, Mexico
Actelion

Completed

Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial Hypertension (SERAPHIN OL)

Pulmonary Arterial Hypertension

United States, United Kingdom, Taiwan, Finland, Canada, Belarus, Belgium, Argentina, Australia, China, Colombia, Croatia, Germany, Hong Kong, India, Israel, Italy, Malaysia, Netherlands, Poland, Russian Federation, South Africa, Tha... and more
United Therapeutics

Completed

Long-term Safety and Efficacy of Ralinepag in Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension

United States, Australia, Bulgaria, Czechia, Hungary, Poland, Romania, Serbia, Slovakia, Spain
Bayer

Completed

Open-Label Long-Term Safety and Efficacy Study of Fixed Dose Combination of Nifedipine Gastrointestinal Therapeutic System and Candesartan Cilexetil in Subjects With Moderate to Severe Essential Hypertension

Hypertension

Germany, United States, Canada, Poland, United Kingdom, Belgium
Acceleron Pharma, Inc., a wholly-owned subsidiary...

Active, not recruiting

A Study of Sotatercept in Participants With PAH WHO FC III or FC IV at High Risk of Mortality (MK-7962-006/ZENITH) (ZENITH)

Pulmonary Arterial Hypertension

France, Germany, United States, Australia, Belgium, Canada, Israel, Italy, Mexico, Netherlands, Spain, United Kingdom
Pfizer

Terminated

A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients With Pulmonary Arterial Hypertension (STRIDE-3)

Pulmonary Arterial Hypertension

United States, Netherlands, Canada, Belgium, France, Germany, Italy, Spain, United Kingdom, Australia, Poland, Austria, Brazil, Israel, Argentina, Mexico
Ratiopharm GmbH

Completed

Cafedrin/Theodrenalin (Akrinor®) Versus Ephedrine for Treatment of Hypotension in the Peri-operative Phase in Inpatient Setting

Hypotension

Germany
GB002, Inc., a wholly owned subsidiary of Gossamer...

Recruiting

Open-label Extension Study of GB002 in Adult Subjects With Pulmonary Arterial Hypertension (PAH)

Pulmonary Arterial Hypertension

United States, Australia, Spain, Czechia, France, Germany, United Kingdom, Belgium
Actelion

Completed

Iloprost Power 15 in Pulmonary Arterial Hypertension (PROWESS 15)

Pulmonary Arterial Hypertension

United States, Austria, Germany
ONL Therapeutics

Active, not recruiting

A Phase 1b Study of ONL1204 Ophthalmic Solution in Patients With Progressing Open Angle Glaucoma

Open Angle Glaucoma

Australia, New Zealand
Actelion

Completed

Safety Study Extension of Iloprost Power 15 in Pulmonary Arterial Hypertension (PROWESS 15 Ext)

Pulmonary Arterial Hypertension

United States, Germany, Austria
Boehringer Ingelheim

Completed

Telmisartan (Micardis) and Amlodipine (Norvasc) - Factorial Design Study for the Treatment of Hypertension

Hypertension

United States, Argentina, Brazil, Mexico, South Africa
Bellerophon Pulse Technologies

Completed

Inhaled Nitric Oxide/INOpulse DS for Pulmonary Arterial Hypertension (PAH) (PAH)

Pulmonary Arterial Hypertension | Pulmonary Hypertension

United States, Canada
AstraZeneca

Recruiting

A Study to Investigate the Efficacy and Safety of Baxdrostat in Participants With Uncontrolled Hypertension on Two or More Medications Including Participants With Resistant Hypertension (BaxHTN)

Resistant Hypertension | Uncontrolled Hypertension

United States, Canada, Italy, South Africa, Korea, Republic of, Australia, Belgium, France, Germany, Poland, Japan, Spain, Vietnam, Argentina, Bulgaria, Turkey, India, Malaysia, Taiwan, Thailand, Austria, Israel, Netherlands, Sweden, United... and more
United Therapeutics

Recruiting

Pulmonary Hypertension Screening in Patients With Interstitial Lung Disease for Earlier Detection (PHINDER)

Pulmonary Hypertension | Interstitial Lung Disease

United States
Actelion

Recruiting

Outcome Study Assessing a 75 Milligrams (mg) Dose of Macitentan in Patients With Pulmonary Arterial Hypertension (UNISUS)

Pulmonary Arterial Hypertension

Belgium, United States, Italy, Canada, Taiwan, Greece, China, Korea, Republic of, Germany, Israel, Austria, Russian Federation, Australia, Thailand, United Kingdom, Brazil, Malaysia, Spain, Ukraine, Bulgaria, Colombia, Mexico, Turkey, Vietna... and more
AbbVie

Active, not recruiting

Evaluation of the Duration of Effect of Bimatoprost SR in Participants With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Open-Angle Glaucoma

United States, Argentina, Australia, Bulgaria, Czechia, Denmark, Germany, Hungary, Ireland, Italy, New Zealand, Poland, Russian Federation, South Africa, Sweden, United Kingdom
University of British Columbia
Canadian Institutes of Health Research (CIHR); Sunnybrook Research Institute

Completed

The CHIPS Trial (Control of Hypertension In Pregnancy Study)

Gestational Hypertension

Canada, United Kingdom, Netherlands, United States, Israel, Australia, Chile, New Zealand, Hungary, Poland, Jordan, Argentina, Brazil, Colombia, Estonia
AbbVie

Completed

Comparison of Bimatoprost Sustained Release (SR) to Selective Laser Trabeculoplasty (SLT) in Adults With Open-Angle Glaucoma or Ocular Hypertension

Ocular Hypertension | Glaucoma, Open-Angle

United States, Australia, Canada, Denmark, France, Germany, Israel, New Zealand, Philippines, Poland, Russian Federation, United Kingdom

Clinical Trials on Intraoperative Hypotension in South Africa

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CROs in Sweden

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