Clinical Trials on Invasive Aspergillosis

Total 1294 results

Pulmocide Ltd

Completed

A Safety Study of PC945 (Opelconazole) Prophylaxis or Pre-emptive Therapy Against Pulmonary Aspergillosis in Lung Transplant Recipients (OPERA-S Study)

Pulmonary Aspergillosis

United States, Canada
Medical University of Graz
Barmherzige Brueder Marschallgasse / Graz

Completed

Influence of Open and Laparoscopic Abdominal Surgery Involving the Intestinal Tract on Serum 1,3-ß-D-Glucan (BDG) Values

Invasive Candidiases

Austria
University Hospital, Basel, Switzerland

Completed

Azole-resistance in Aspergillus

Pulmonary Aspergillosis

Switzerland
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Children's Hospital...

Completed

PEACE: Pediatric Antifungal Comparative Effectiveness (PEACE)

Pediatric Invasive Candidiasis

United States, Colombia, Canada, India, Saudi Arabia, Greece, Italy, Spain
University of Cologne

Recruiting

ECMM Candida Registry - CandiReg (CandiReg)

Invasive Candidiases

Germany
Centre Hospitalier Universitaire Dijon

Completed

Evaluate the Performance of Genetic Amplification by Polymerase Chain Reaction (PCR) and the "Mannan Antigenemia and Antimannan Antibodies Couple as a Means of Diagnosis and a Marker of Follow-up in Invasive Candidiasis. (EMPIRICAND)

Invasive Candidiasis; Treatment With Echinocandin

France
Hôpital Haut Lévêque
Institut National de la Santé Et de la Recherche Médicale, France; University...

Completed

Lung MRI and Allergic Broncho-pulmonary Aspergillosis in Cystic Fibrosis (MRAB)

Pulmonary Cystic Fibrosis | ABPA

France
Research Institute of Epidemiology, Microbiology...

Active, not recruiting

Pulmonary Aspergillosis in Tuberculosis Patients

Aspergillosis | Pulmonary Tuberculoses | Old Tuberculosis | Active Tuberculosis | Chronic Pulmonary Aspergillosis

Uzbekistan
University of Bologna

Unknown

A B-D-Glucan Driven Antifungal Stewardship Approach for Invasive Candidiasis

Invasive Candidiases | Abdominal Infection

Italy
Medical University of Graz
Medical University Innsbruck

Completed

NOBICS - NOvel BIomarker In Invasive CandidiasiS/Candida Sepsis (NOBICS)

Invasive Candidiasis

Austria
Fadoi Foundation, Italy

Terminated

Comparison of Two Diagnostic Tests in Patients With Suspected Invasive Candidiasis in Internal Medicine Wards and Who Are Currently Timely Treated With Micafungin (EPICA1)

Invasive Candidiasis

Italy
Kevin Watt

Completed

Pharmacokinetics of Micafungin in Children on Extracorporeal Membrane Oxygenation

Invasive Candidiasis

United States
Duke University
Pfizer

Completed

β-D-Glucan (BDG) Surveillance With Preemptive Anidulafungin vs. Standard Care for Invasive Candidiasis in Surgical Intensive Care Unit (SICU) Patients

Invasive Candidiasis

United States
University Hospital, Lille

Recruiting

Early Discontinuation of Empirical Antifungal Therapy and Biomarkers (SEAT)

Invasive Candidiasis

France
University Hospital, Limoges

Completed

Pharmacokinetics of Micafungin in Patients of Intensive Care Units (MI-K)

Invasive Candidiasis

France
University Medical Center Groningen

Completed

Variability of Fluconazole Concentration in Critically Ill Patients

Invasive Candidiasis

Netherlands
Merck Sharp & Dohme LLC

Completed

A Multicenter, Randomized, Double-Blind, Comparative Study to Evaluate the Safety, Tolerability, and Efficacy of 2 Dosing Regimens of an Antifungal Drug in the Treatment of Fungal Infections in Adults (0991-801)(COMPLETED)

Invasive Candidiasis
Merck Sharp & Dohme LLC
Mycoses Study Group

Terminated

Pilot Feasibility Study With Patients Who Are at High Risk For Developing Invasive Candidiasis in a Critical Care Setting (MK-0991-067)

Invasive Candidiasis
University Hospital, Grenoble

Completed

Empirical Antifungal Treatment in ICUS (EMPIRICUS)

Invasive Candidiasis

France
Mycoses Study Group
Merck Sharp & Dohme LLC

Completed

Randomized Study of Caspofungin Prophylaxis Followed by Pre-emptive Therapy for Invasive Candidiasis in the Intensive Care Unit (ICU) (MSG-01)

Invasive Candidiasis

United States
University Medical Center Groningen

Completed

Optimal Dosage of Caspofungin in Critically Ill Patients

Critically Ill | Suspected Invasive Candidiasis

Netherlands
Yung Shin Pharm. Ind. Co., Ltd.

Completed

Evaluate Bioequivalence of Micafungin (50mg/Vial)

Invasive Candidiasis

Taiwan
Duke University
Children's Hospital of Philadelphia

Completed

BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia (BIOPIC)

Invasive Candidiasis

United States, Saudi Arabia, Greece, Spain
Merck Sharp & Dohme LLC

Terminated

Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants (MK-0991-064)

Candidiasis, Invasive
Hasan Al-Dorzi
King Fahad Medical City

Completed

Invasive Candidiasis in Saudi ICUs (ICIP-SA)

Invasive Candidiasis

Saudi Arabia
Pfizer
Vicuron Pharmaceuticals

Completed

The Safety and Effectiveness of Intravenous Anidulafungin as a Treatment for Patients With Invasive Candidiasis.

Candidiasis

United States
Hospital Universitario La Fe

Completed

Predictive Factors of Mortality in Invasive Fungal Disease in Post-surgical Critical Care Unit (FPR-IIS)

Fungal Invasive Disease

Spain
Astellas Pharma Inc

Completed

A Study to Evaluate Pre-emptive Treatment for Invasive Candidiasis in High Risk Surgical Subjects (INTENSE)

Mycoses

Belgium, Germany, Spain, France, Italy, Turkey, Austria, Switzerland, Hungary, United Kingdom, Israel, Denmark, Greece, Finland, Romania
Pfizer

Completed

An Open-label Study of APX001 for Treatment of Patients With Candidemia/Invasive Candidiasis Caused by Candida Auris (APEX)

Candidemia | Candida Infection | Invasive Candidiases

South Africa
Robert Krause, MD

Completed

Candida Spp. in the Lower Respiratory Tract: Harmless Residents or Pathogen?

Invasive Candidiasis | Pulmonary Candidiasis

Austria
Grupo Espanol de trasplantes hematopoyeticos y...

Completed

Aspergillus PCR Early Detection in High Risk Oncohematological Patients (PCRAGA)

Infections

Spain
Merck Sharp & Dohme LLC

Completed

An Observational Study of Fungal Biomarkers (MK-0000-089)

Aspergillosis
Astellas Pharma Inc

Terminated

Trial of Micafungin (FK463) in Combination With Liposomal Amphotericin B (AmBisome) for Aspergillosis

Aspergillosis

United States
University Hospital Inselspital, Berne

Completed

Surveillance of Fungal Infections During Construction Activity

Aspergillosis

Switzerland
Mayo Clinic

Recruiting

The Role Of Interferon-gamma In Immune Responses To Invasive Candidiasis

Candidiasis | Fungal Infection

United States
Merck Sharp & Dohme LLC

Completed

A Study of Caspofungin Acetate (MK0991) for the Treatment of Esophageal Candidiasis or Invasive Candidiasis in Chinese Adults (MK-0991-066)

Fungal Infection
Services Institute of Medical Sciences, Pakistan

Completed

Efficacy of Prophylactic Fluconazole Therapy in Preterm and Very Low Birth Weight Neonates in Preventing Invasive Fungal Infection.

Invasive Candidiases

Pakistan
University of Arkansas

Withdrawn

Trial of Combination Antifungal Therapy (Vori+Mica vs. Vori+Placebo) in Invasive Aspergillosis

Aspergillosis

United States
Pfizer

Terminated

Study to Test the Combination of Voriconazole and Anidulafungin in Patients Who Have, or Are Thought to Have, Invasive Aspergillosis and Who Are Unable to Take a Common Antifungal Therapy (Polyene)

Aspergillosis

United States
Assiut University

Completed

THYME AND CARVACROLL Nanoparticle Effect on Fungi

Aspergillosis

Egypt
Astellas Pharma Inc

Completed

Study of FK463 for the Treatment of Invasive Aspergillosis

Aspergillosis

United Kingdom, Austria, France, Germany, Italy, Poland, Spain, Sweden
Merck Sharp & Dohme LLC

Completed

MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037)

Aspergillosis
Pfizer

Completed

Anidulafungin Plus Voriconazole Versus Voriconazole For The Treatment Of Invasive Aspergillosis

Aspergillosis

United States, Australia, Canada, Greece, Belgium, Germany, Korea, Republic of, Poland, Russian Federation, Spain, Turkey, Thailand, Brazil, Czech Republic, France, India, Italy, Netherlands, Peru, Portugal, Singapore, Switzerland, ... and more
Pfizer
Vicuron Pharmaceuticals

Completed

A Safety & Effectiveness Study of Intravenous Anidulafungin With AmBisome® for Treatment of Invasive Aspergillosis (IA).

Aspergillosis

United States
Cidara Therapeutics Inc.

Completed

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

Mycoses | Candidemia | Fungal Infection | Invasive Candidiases

United States, Israel, Spain, Korea, Republic of, Taiwan, Singapore, Thailand, Australia, China, Turkey, Belgium, Germany, France, Argentina, Bulgaria, Colombia, Greece, Italy
Fujian Shengdi Pharmaceutical Co., Ltd.

Not yet recruiting

A Trial of Intravenous HRS9432 in the Treatment of Subjects With Candidemia and/or Invasive Candidiasis

Patients With Candidemia and/or Invasive Candidiasis
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Serratus Plane Block After Minimally Invasive Mitral Valve Repair

Serratus Anterior Plane Block | Minimal Invasive Cardiac Surgery | Minimal Invasive Cardiac Surgery Mitral Valve Surgery

Germany
University Medical Center Groningen

Completed

Pharmacokinetics of Micafungin in Critically Ill Patients

Critical Illness | Invasive Candidiasis

Netherlands
Fundació Institut de Recerca de l'Hospital de la...
Sociedad Española de Neumología y Cirugía Torácica; Societat Catalana de Pneumologia...

Recruiting

Telemonitoring Utility in the Process of Adaptation to Home Mechanical Ventilation (HMV)

Non Invasive Ventilation

Spain
Felix JF Herth
DLR German Aerospace Center; University Hospital Heidelberg; Federal Joint Committee and other collaborators

Recruiting

Early Detection and Early Intervention Program in High-risk Patients to Avoid Invasive Long-term Ventilation (PRiVENT)

Weaning | Invasive Ventilation

Germany

Clinical Trials on Invasive Aspergillosis

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