Clinical Trials on Invasive Fungal Infection in United Kingdom

Total 21381 results

Mayo Clinic

Recruiting

The Role Of Interferon-gamma In Immune Responses To Invasive Candidiasis

Candidiasis | Fungal Infection

United States
Medical Research Council

Completed

Liposomal Amphotericin B With or Without Sargramostim in Treating Patients With Invasive Fungal Infection

Infection

United Kingdom
St George's University Hospitals NHS Foundation...
University College, London; St George's, University of London; University of... and other collaborators

Recruiting

LFD of Aspergillus Antigen in Paediatrics (LFD-AsPaeds)

Invasive Pulmonary Aspergillosis | Invasive Fungal Disease

United Kingdom
Pfizer
European Society for Blood and Marrow Transplantation

Completed

Voriconazole for Secondary Prophylaxis of Invasive Fungal Infections in Patients With Allogeneic Stem Cell Transplants (VOSIFI)

Prophylaxis Of Invasive Fungal Infections

Portugal, Belgium, France, Germany, Spain, United Kingdom, Switzerland, Sweden
Astellas Pharma Global Development, Inc.

Completed

Registry of Patients Treated With Systemic Mold-Active Triazoles

Invasive Fungal Infection

United States
Cidara Therapeutics Inc.

Recruiting

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation (ReSPECT)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis | Invasive Fungal Disease | Pneumocystis | Mold Infection | Prophylaxis of Invasive Fungal Infections | Aspergillus

United States, Germany, France, Belgium, Canada, Italy, Spain, United Kingdom, Turkey, Switzerland
Merck Sharp & Dohme LLC

Recruiting

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

Invasive Fungal Infection

Israel, United States, Belgium, Greece, Peru, Poland, Mexico, Russian Federation
National Cancer Institute (NCI)

Completed

Early Molecular Detection for the Improved Diagnosis of Invasive Pulmonary Aspergillosis and Invasive Pulmonary Zygomycosis

Invasive Pulmonary Aspergillosis | Immunocompromised Host | Invasive Pulmonary Fungal Infection | Invasive Pulmonary Zygomycosis

United States
Astellas Pharma Inc
Basilea Pharmaceutica International Ltd

Completed

Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis

Aspergillosis | Invasive Fungal Infection

Korea, Republic of, Belgium, Australia, United States, Germany, Switzerland, Israel, Canada, Argentina, Chile, Malaysia, Thailand, France, Russian Federation, Hungary, Spain, Brazil, China, India, Egypt, Italy, Turkey, Netherlands, Me... and more
Pfizer

Completed

Voriconazole Versus Itraconazole In Primary Prophylaxis Of Invasive Fungal Infection (IFI) In Subjects With Allogeneic Hematopoietic Stem Cell Transplants (HSCT) (IMPROVIT)

Antifungal Prophylaxis of Invasive Fungal Infections

Canada, Spain, Greece, France, Portugal, United Kingdom, Czech Republic, Egypt, Jordan, Russian Federation, Switzerland, Turkey
Gilead Sciences

Completed

Prevention of Invasive Fungal Infections (IFIs) in Subjects Receiving Chemotherapy for Acute Lymphoblastic Leukemia (AmBiGuard)

Invasive Fungal Disease

United Kingdom
Mundipharma Research Limited

Recruiting

Rezafungin Paediatric PK Study in Paediatric Subjects From Birth to <18 Years of Age

Invasive Fungal Infections

Spain, United Kingdom, Germany
University of Pittsburgh
Schering-Plough

Terminated

Limited Access Protocol of Posaconazole in Invasive Fungal Infections Study PO2095

Fungal Infection

United States
Cidara Therapeutics Inc.

Completed

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

Mycoses | Candidemia | Fungal Infection | Invasive Candidiases

United States, Israel, Spain, Korea, Republic of, Taiwan, Singapore, Thailand, Australia, China, Turkey, Belgium, Germany, France, Argentina, Bulgaria, Colombia, Greece, Italy
University of Pittsburgh
Astellas Pharma US, Inc.

Completed

Invasive Fungal Infections Surveillance Initiative

Fungal Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

An Open Label, Non-Comparative, Multicenter, Phase III Trial of the Efficacy, Safety and Toleration of Voriconazole in the Primary or Secondary Treatment of Invasive Fungal Infections

Mycoses

United States
Arkansas Children's Hospital Research Institute
National Institute of Allergy and Infectious Diseases (NIAID); Children's Hospital...

Recruiting

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections (DOMINIC)

Pulmonary Invasive Fungal Infections | Pulmonary Invasive Aspergillosis

United States, Canada
Cidara Therapeutics Inc.

Completed

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension (STRIVE)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis

United States, Spain, Belgium, Russian Federation, Greece, Bulgaria, Canada, Hungary, Italy, Romania
Pfizer

Completed

Study Of The Pharmacokinetics And Safety Of Voriconazole In Children 2 To 11 Years Old Who Are At High Risk For Systemic Fungal Infection

Candidemia | Candidiasis

United States
Michael Cohen-Wolkowiez

Completed

Anidulafungin PK in Infants and Toddlers

Invasive Fungal Infections

United States
Pfizer

Completed

A Bioequivalence Study of APX001 High-load and Low-load Tablets

Invasive Fungal Infections

United States
F2G Biotech GmbH
Iqvia Pty Ltd

Recruiting

Evaluate F901318 Treatment of Invasive Fungal Infections in Patients Lacking Treatment Options (FORMULA-OLS)

Invasive Fungal Infections

United States, Netherlands, Israel, Spain, Korea, Republic of, Belgium, Australia, Germany, France, Brazil, Poland, Egypt, Russian Federation, Thailand, Turkey, United Kingdom, Vietnam
National Institute of Allergy and Infectious Diseases...

Completed

Comparison of Two Treatments to Prevent Invasive Fungal Infections in Patients Who Have Received Liver Transplants

Candidiasis

United States
Kevin Watt

Completed

Pharmacokinetics of Micafungin in Children on Extracorporeal Membrane Oxygenation

Invasive Candidiasis

United States
Duke University
Pfizer

Completed

β-D-Glucan (BDG) Surveillance With Preemptive Anidulafungin vs. Standard Care for Invasive Candidiasis in Surgical Intensive Care Unit (SICU) Patients

Invasive Candidiasis

United States
Scynexis, Inc.
Inncelerex

Completed

ADME Study of [14C]-Ibrexafungerp in Healthy Male Subjects

Fungal Infection

United Kingdom
Pfizer

Completed

A Study to Assess the Mass Balance Recovery and Metabolite Profile & Identification of [14C]-APX001 in Healthy Males

Fungal Infection

United Kingdom
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Voriconazole and Caspofungin Acetate in Treating Invasive Fungal Infections in Patients With Weakened Immune Systems

Unspecified Adult Solid Tumor, Protocol Specific | Infection

United States
Pfizer
Vicuron Pharmaceuticals

Completed

The Safety and Effectiveness of Intravenous Anidulafungin as a Treatment for Patients With Invasive Candidiasis.

Candidiasis

United States
Astellas Pharma Inc

Completed

A Study to Evaluate Pre-emptive Treatment for Invasive Candidiasis in High Risk Surgical Subjects (INTENSE)

Mycoses

Belgium, Germany, Spain, France, Italy, Turkey, Austria, Switzerland, Hungary, United Kingdom, Israel, Denmark, Greece, Finland, Romania
Astellas Pharma Inc

Terminated

Comparative Study of Micafungin (FK463) Versus Placebo as Prophylactic Antifungal Therapy in the ICU

Invasive Fungal Infections

United States, Canada
National Cancer Institute (NCI)

Completed

Comparing the Effectiveness of Fluconazole and a New Medicine (FK463) in Preventing Fungal Infections in Bone Marrow Transplant Patients

Mycoses | Candidiasis | Fungemia | Aspergillosis

United States
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); Children's Hospital...

Completed

PEACE: Pediatric Antifungal Comparative Effectiveness (PEACE)

Pediatric Invasive Candidiasis

United States, Colombia, Canada, India, Saudi Arabia, Greece, Italy, Spain
Mycoses Study Group
Merck Sharp & Dohme LLC

Completed

Randomized Study of Caspofungin Prophylaxis Followed by Pre-emptive Therapy for Invasive Candidiasis in the Intensive Care Unit (ICU) (MSG-01)

Invasive Candidiasis

United States
M.D. Anderson Cancer Center
Enzon Pharmaceuticals, Inc.

Completed

Oral Posaconazole Three Times Per Day vs Weekly High Dose Amphotericin B Lipid Complex (ABLC)

Invasive Fungal Infections | Hematologic Malignancies

United States
Karius, Inc.
Ann & Robert H Lurie Children's Hospital of Chicago

Completed

Evaluation of NGS for Detection and Follow-up of Fungal Pathogens in Immunocompromised Pediatric Patients

Invasive Fungal Infections | Immunocompromised | Invasive Fungal Disease | Fever and Neutropenia

United States
Duke University
Children's Hospital of Philadelphia

Completed

BIOPIC: Fungal Biomarkers for Diagnosis and Response to Therapy for Pediatric Candidemia (BIOPIC)

Invasive Candidiasis

United States, Saudi Arabia, Greece, Spain
HelixBind, Inc.

Unknown

Assessment of Assay for Rapid Identification of Bloodstream Infections From Whole Blood

Candidemia | Bacteremia

United States
Astellas Pharma Inc

Completed

Study of FK463 in the Treatment of Candidemia or Invasive Candidiasis

Candidiasis

United Kingdom, Austria, France, Germany, Italy, Poland, Spain, Sweden
Pfizer

Terminated

Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds (AEGIS)

Invasive Fungal Infections

Israel, Germany, United States, Belgium
National Cancer Institute (NCI)

Completed

Surveillance of Fungal Infections in Bone Marrow/Stem Cell and Organ Transplant Recipients

Fungus Disease

United States
Astellas Pharma Inc
Basilea Pharmaceutica

Completed

Isavuconazole (BAL8557) in the Treatment of Candidemia and Other Invasive Candida Infections

Mycoses | Candidemia | Candidiasis, Invasive

Philippines, New Zealand, United States, Spain, Belgium, Canada, Israel, Malaysia, Mexico, Italy, Australia, Germany, Singapore, Hungary, Brazil, Thailand, China, India, Argentina, France, Russian Federation, Chile, Lebanon, South Africa and more
Johns Hopkins University
National Institutes of Health (NIH)

Recruiting

Biodistribution and Pathophysiology Study of 18F-Fluorodeoxysorbitol (18F-FDS) in Diseased Patients

Invasive Fungal Infections | Inflammatory Disease | Oncologic Disease | Enterobacterial Infections

United States
Pfizer

Completed

Study To Assess Pharmacokinetics, Safety & Efficacy of Anidulafungin When Treating Children With Invasive Candidiasis

Candidemia

United States, Taiwan, Spain, United Kingdom, Korea, Republic of, Brazil, Greece, Canada, Italy, Russian Federation
University of Alabama at Birmingham
Astellas Pharma Inc; Centers for Disease Control and Prevention

Recruiting

COVID-19 Associated Pulmonary Aspergillosis (CAPA) and Other Invasive Fungal Infections (IFI) (CAPA IFI)

Covid19 | Fungal Infection | Aspergillosis

United States
Pulmocide Ltd

Recruiting

Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study)

Refractory IPA

Spain, United States, Canada, Italy, Austria, France, Israel, United Kingdom, Belgium, Korea, Republic of, Brazil, Germany, Chile, Greece, Taiwan, Argentina, Colombia
Scynexis, Inc.

Completed

Study to Evaluate the Safety and Efficacy of the Coadministration of Ibrexafungerp (SCY-078) With Voriconazole in Patients With Invasive Pulmonary Aspergillosis (SCYNERGIA)

Invasive Pulmonary Aspergillosis

United States, Belgium, Canada, Germany, South Africa
Pfizer
Vicuron Pharmaceuticals

Completed

The Safety and Efficacy of Anidulafungin Versus Comparator in Patients With Candidemia and Invasive Candidiasis

Candidiasis

United States
Pfizer

Completed

Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study (ICE)

Invasive Candidiasis

Czech Republic, Belgium, Austria, Portugal, Russian Federation, Turkey, Canada, Germany, Italy, United Kingdom, Hungary, France, Slovakia, Denmark, Romania, Netherlands, Poland, Greece, Ukraine
Vical

Terminated

VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults

Invasive Aspergillosis | Invasive Pulmonary Aspergillosis

United States, Korea, Republic of, Canada, Belgium, France, Germany

Clinical Trials on Invasive Fungal Infection in United Kingdom

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