Clinical Trials on Invasive Pneumococcal Disease (IPD) in Belgium

Total 79 results

GlaxoSmithKline

Completed

Safety and Efficacy Study of Investigational Pneumococcal Vaccine in Elderly Population

Prophylaxis Invasive Pneumococcal Diseases and Pneumonia

Belgium
GlaxoSmithKline

Completed

Safety and Immune Response Study of an Investigational Pneumococcal Vaccine.

Prophylactic Pneumococcal Diseases

Belgium
GlaxoSmithKline

Completed

Study to Evaluate Safety, Reactogenicity and Immunogenicity of the Pneumococcal Protein PhtD Vaccine in Healthy Adults

Pneumococcal Disease

Belgium
Pulmocide Ltd

Recruiting

Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study)

Refractory IPA

Spain, United States, Canada, Italy, Austria, France, Israel, United Kingdom, Belgium, Korea, Republic of, Brazil, Germany, Chile, Greece, Taiwan, Argentina, Colombia
Pierre Van Damme
Centre Hospitalier Intercommunal Creteil; University of Bristol; University Ghent and other collaborators

Completed

Carriage of Streptococcus Pneumoniae in Infants With Acute Otitis Media and in Infants Attending Day-care Centers

Streptococcus Pneumoniae | Nasopharyngeal Carriage

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Invasive Pulmonary Aspergillosis Complicating Influenza Infection

Influenza With Pneumonia | Aspergillosis Invasive

Belgium
Universitaire Ziekenhuizen KU Leuven

Completed

Evaluation of Exhaled Breath Condensate in the Diagnosis of Invasive Pulmonary Aspergillosis

Invasive Pulmonary Aspergillosis

Belgium
Sciensano
Merck Sharp & Dohme LLC; Pfizer; Universitaire Ziekenhuizen KU Leuven

Recruiting

Surveillance of Non-invasive Streptococcus Pneumoniae Infections in Belgium (STREPTO)

Pneumonia | Otitis Media | Sinusitis Bacterial

Belgium
Universitaire Ziekenhuizen KU Leuven

Unknown

Novel Biomarkers for Invasive Aspergillosis

Aspergillosis Invasive

Belgium
Combioxin SA

Completed

Safety, Tolerability, Efficacy and Pharmacodynamics of CAL02 in Severe Pneumonia Caused by Streptococcus Pneumoniae

Pneumonia | Pneumococcal Infections

France, Belgium
Universitaire Ziekenhuizen KU Leuven

Recruiting

Influenza Associated Aspergillosis In-depth Investigation (PIAS)

Invasive Pulmonary Aspergillosis | Influenza With Pneumonia

Belgium
Jules Bordet Institute

Completed

Genomic Grade Index (GGI): Feasibility in Routine Practice and Impact on Treatment Decisions in Early Breast Cancer

Invasive Breast Cancer

Belgium
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucormycosis (IM) in Pediatric Participants

Invasive Aspergillosis | Invasive Mucormycosis

United States, Belgium, Spain
University Hospital, Geneva
University of Lausanne Hospitals; University Hospital St Luc, Brussels; University... and other collaborators

Completed

Neurally Adjusted Ventilatory Assist for Non Invasive Ventilation and Patient-ventilator Interaction

Non Invasive Ventilation | Patient Ventilator Interaction

Belgium, Switzerland
University of Cologne

Completed

Caspofungin Maximum Tolerated Dose in Patients With Invasive Aspergillosis

Invasive Aspergillosis

Germany, Belgium
Janssen Research & Development, LLC

Active, not recruiting

A Study of 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) and High-dose Quadrivalent Influenza Vaccine, With and Without Co-administration, in Adults Aged 65 Years or Older (Engage)

Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention

United States, Poland, Belgium, Canada
Pfizer

Completed

20-valent Pneumococcal Conjugate Vaccine Safety and Immunogenicity Study of a 3-Dose Series in Healthy Infants

Pneumococcal Disease

Denmark, Belgium, Australia, Poland, Norway, Finland, Netherlands, Italy, Czechia, Estonia, Russian Federation, Slovakia
Radboud University Medical Center

Completed

Pharmacokinetics of Micafungin Given Twice Weekly Intravenously Compared to Micafungin Given Daily to Patients at Risk for Developing an Invasive Fungal Disease (MATADOR)

Allogeneic Stem Cell Transplant | Acute Myeloid Leucaemia | Myelo Dysplastic Syndrome | Acute Graft Versus Host Disease Grade II-IV

Netherlands, Belgium
Erasmus Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Stichting...

Terminated

Azole-echinocandin Combination Therapy for Invasive Aspergillosis (IA-DUET)

Invasive Aspergillosis

Belgium, Netherlands
Cliniques universitaires Saint-Luc- Université...

Active, not recruiting

Mechanically-Assisted and Non-Invasive Ventilation for Breathing-related Tumor Motion Mitigation. (MANIV)

Optimization of Motion Mitigation Strategies by Mechanically-Assisted Non-Invasive Ventilation

Belgium
Merck Sharp & Dohme LLC

Completed

Safety and Immunogenicity of V116 in Adults Living With Human Immunodeficiency Virus (HIV) (V116-007, STRIDE-7)

Pneumococcal Disease

United States, Belgium, Chile, France, South Africa, Thailand
Astellas Pharma Inc

Completed

A Study to Evaluate Pre-emptive Treatment for Invasive Candidiasis in High Risk Surgical Subjects (INTENSE)

Mycoses

Belgium, Germany, Spain, France, Italy, Turkey, Austria, Switzerland, Hungary, United Kingdom, Israel, Denmark, Greece, Finland, Romania
Pfizer
European Society for Blood and Marrow Transplantation

Completed

Voriconazole for Secondary Prophylaxis of Invasive Fungal Infections in Patients With Allogeneic Stem Cell Transplants (VOSIFI)

Prophylaxis Of Invasive Fungal Infections

Portugal, Belgium, France, Germany, Spain, United Kingdom, Switzerland, Sweden
Scynexis, Inc.

Completed

Study to Evaluate the Safety and Efficacy of the Coadministration of Ibrexafungerp (SCY-078) With Voriconazole in Patients With Invasive Pulmonary Aspergillosis (SCYNERGIA)

Invasive Pulmonary Aspergillosis

United States, Belgium, Canada, Germany, South Africa
Vitadx
FONDATION FORCE POUR L'INNOVATION ET LA RECHERCHE EN SANTE

Recruiting

Demonstration of the Medical Interest of the VisioCyt® Artificial Intelligence Test (DMIA)

Non-muscle Invasive Bladder Cancer (NMIBC)

France, Belgium, Spain
Cidara Therapeutics Inc.

Recruiting

Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation (ReSPECT)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis | Invasive Fungal Disease | Pneumocystis | Mold Infection | Prophylaxis of Invasive Fungal Infections | Aspergillus

United States, Germany, France, Belgium, Canada, Italy, Spain, United Kingdom, Turkey, Switzerland
Universitaire Ziekenhuizen KU Leuven

Unknown

Whole Body Diffusion MRI for Non-invasive Lesion Detection and Therapy Follow-up: Study With Patients With Gastro-intestinal Tumors (s51240)

Non-invasive | Gastro-intestinal Tumor | Accurate Staging | Whole-body Diffusion Weighted MRI

Belgium
Merck Sharp & Dohme LLC

Recruiting

Posaconazole (MK-5592) Intravenous and Oral in Children (<2 Years) With Invasive Fungal Infection (MK-5592-127)

Invasive Fungal Infection

Israel, United States, Belgium, Greece, Peru, Poland, Mexico, Russian Federation
Cidara Therapeutics Inc.

Completed

Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis (ReSTORE)

Mycoses | Candidemia | Fungal Infection | Invasive Candidiases

United States, Israel, Spain, Korea, Republic of, Taiwan, Singapore, Thailand, Australia, China, Turkey, Belgium, Germany, France, Argentina, Bulgaria, Colombia, Greece, Italy
Pfizer

Completed

Anidulafungin Candidemia/Invasive Candidiasis Intensive Care Study (ICE)

Invasive Candidiasis

Czech Republic, Belgium, Austria, Portugal, Russian Federation, Turkey, Canada, Germany, Italy, United Kingdom, Hungary, France, Slovakia, Denmark, Romania, Netherlands, Poland, Greece, Ukraine
Vical

Terminated

VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults

Invasive Aspergillosis | Invasive Pulmonary Aspergillosis

United States, Korea, Republic of, Canada, Belgium, France, Germany
University Hospital, Ghent
Kom Op Tegen Kanker

Recruiting

Evaluating the Impact of 18F-FDG-PET-CT on Risk Stratification and Treatment Adaptation for Patients With Muscle Invasive Bladder Cancer (EFFORT-MIBC)

Muscle-Invasive Bladder Carcinoma

Belgium
Cidara Therapeutics Inc.

Completed

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis-Bridging Extension (STRIVE)

Mycoses | Candidemia | Fungemia | Fungal Infection | Invasive Candidiasis

United States, Spain, Belgium, Russian Federation, Greece, Bulgaria, Canada, Hungary, Italy, Romania
Scynexis, Inc.

Suspended

A Phase 3, Randomized, Double-blind Study for Patients With Invasive Candidiasis Treated With IV Echinocandin Followed by Either Oral Ibrexafungerp or Oral Fluconazole (MARIO)

Candidemia | Candidiasis, Invasive

United States, Korea, Republic of, Greece, Canada, France, Belgium, Germany, Italy, Spain, South Africa, Bulgaria, Israel
Pfizer

Completed

An Efficacy and Safety Study of APX001 in Non-Neutropenic Patients With Candidemia

Candidemia

Germany, United States, Israel, Spain, Belgium
XEOS Medical

Recruiting

Specimen PET-CT Imaging for Intraoperative Margin Assessment in Breast Cancer (BrIMA)

Breast Cancer | Breast Cancer Invasive | Breast Cancer in Situ

Belgium
Astellas Pharma Inc

Completed

Study of Micafungin in Patients With Invasive Candidiasis or Candidemia

Candidemia | Candidiasis

Belgium, France, Germany, Spain, United States, India, Canada, Brazil, Switzerland, Austria, Croatia, Netherlands, Poland, Czech Republic, United Kingdom
Radboud University Medical Center
Universitaire Ziekenhuizen KU Leuven

Completed

Pharmacokinetics of Posaconazole (Noxafil®) as Prophylaxis for Invasive Fungal Infections (PIRAÑA)

Acute Graft Versus Host Disease | Allogeneic Stem Cell Transplant | Acute Myeloid Leucaemia | Myelo Dysplastic Syndrome

Belgium, Netherlands
Astellas Pharma Inc
Basilea Pharmaceutica International Ltd

Completed

Isavuconazole (BAL8557) for Primary Treatment of Invasive Aspergillosis

Aspergillosis | Invasive Fungal Infection

Korea, Republic of, Belgium, Australia, United States, Germany, Switzerland, Israel, Canada, Argentina, Chile, Malaysia, Thailand, France, Russian Federation, Hungary, Spain, Brazil, China, India, Egypt, Italy, Turkey, Netherlands, Me... and more
Universitaire Ziekenhuizen KU Leuven
Merck Sharp & Dohme LLC

Completed

Posaconazole for the Prevention of Influenza-associated Aspergillosis in Critically Ill Patients (POSA-FLU)

Aspergillosis; Pulmonary, Invasive (Etiology)

Belgium, Netherlands
Pfizer

Terminated

Open-label Study of APX001 for Treatment of Patients With Invasive Mold Infections Caused by Aspergillus or Rare Molds (AEGIS)

Invasive Fungal Infections

Israel, Germany, United States, Belgium
Merck Sharp & Dohme LLC

Completed

Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)

Invasive Aspergillosis

Belgium, United States, Greece, Hungary, Israel, Italy, Korea, Republic of, Mexico, Peru, Russian Federation
Jules Bordet Institute
Merck KGaA, Darmstadt, Germany

Active, not recruiting

Avelumab as Neoadjuvant Therapy in Subjects With Urothelial Muscle Invasive Bladder Cancers (AURA Trial) (AURA)

Non-metastatic Muscle Invasive Bladder Cancer

France, Belgium
Astellas Pharma Inc

Terminated

Micafungin Salvage Mono-therapy in Invasive Aspergillosis

Invasive Aspergillosis

Poland, Belgium, Spain, France, Germany, Colombia, Brazil, Argentina, Hungary, Czech Republic, Croatia, Italy
Jules Bordet Institute
Hoffmann-La Roche

Recruiting

Neoadjuvant Study of Targeting ROS1 in Combination With Endocrine Therapy in Invasive Lobular Carcinoma of the Breast (ROSALINE) (ROSALINE)

HER2-negative Breast Cancer | ER+ Breast Cancer | Invasive Lobular Breast Carcinoma

Belgium, France
AstraZeneca

Active, not recruiting

Assessment of Efficacy and Safety of Durvalumab Plus BCG Compared to the Standard Therapy With BCG in Non-muscle Invasive Bladder Cancer (POTOMAC)

Non-muscle-invasive Bladder Cancer

France, Spain, Belgium, Canada, Poland, Germany, Japan, Russian Federation, United Kingdom, Austria, Australia, Netherlands
UNICANCER
Hoffmann-La Roche

Active, not recruiting

Atezolizumab Plus One-year BCG Bladder Instillation in BCG-naive High-risk Non-muscle Invasive Bladder Cancer Patients (ALBAN)

Bladder Cancer

Spain, France, Belgium
Pfizer

Terminated

An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Deep Tissue Infection Due To Candida

Candidiasis | Fungemia

Belgium, United States, Canada, Switzerland, Netherlands, Bulgaria, Portugal, Romania, Russian Federation
F2G Biotech GmbH
Iqvia Pty Ltd; Shionogi

Recruiting

Olorofim Aspergillus Infection Study (OASIS)

Invasive Aspergillosis

United States, Taiwan, Belgium, Spain, Italy, Turkey, New Zealand, China, Canada, Netherlands, Australia, Brazil, Singapore, Israel, France, Thailand, Germany, Japan, Korea, Republic of, United Kingdom
Respivant Sciences GmbH
Respivant Sciences Inc.

Terminated

A Phase 2b Study of Inhaled RVT-1601 for the Treatment of Persistent Cough in IPF (SCENIC)

Chronic Cough | IPF | Persistent Cough in IPF

United States, United Kingdom, Netherlands, Australia, Belgium, New Zealand, Turkey, Italy, Germany, Czechia, Canada

Clinical Trials on Invasive Pneumococcal Disease (IPD) in Belgium

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