Clinical Trials on Invasive Streptococcus Pneumoniae Disease

Total 11026 results

University of Oxford
Pfizer

Unknown

Understanding Pneumococcal Carriage and Disease 2017-2020

Streptococcal Pneumonia | Streptococcus Pneumoniae Infection | Streptococcus Pneumoniae, Invasive Disease

United Kingdom
Universidad de la Sabana

Recruiting

Pneumococcal Nasopharyngeal Colonization as Predictor of Community-Acquired Pneumonia (CAP) in Adults With Chronic Diseases. (CAP)

Community-acquired Pneumonia | Streptococcus Pneumoniae Infection | Streptococcus Pneumoniae Pneumonia | Streptococcus Pneumoniae Infection Invasive

Colombia
University of British Columbia
Canadian Institutes of Health Research (CIHR); University of Calgary; Alberta... and other collaborators

Completed

CIRN Pneumococcal Conjugate Vaccine 1 vs. 2 Dose Priming Study

Streptococcus Pneumoniae Infection | Invasive Pneumococcal Disease, Protection Against

Canada
London School of Hygiene and Tropical Medicine
University College, London; Bill and Melinda Gates Foundation; Wellcome Trust; KEMRI-Wellcome... and other collaborators

Active, not recruiting

The Effect of Fractional Doses of Pneumococcal Conjugate Vaccines on Immunogenicity and Carriage in Kenyan Infants (FPCV)

Pneumococcal Infection | Streptococcus Pneumoniae Infection | Invasive Pneumococcal Disease, Protection Against

Kenya
GlaxoSmithKline

Completed

Primary Vaccination With Either Synflorix™ or Prevenar 13™ or Both Vaccines and Booster Vaccination With Synflorix™

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Mexico
GlaxoSmithKline

Completed

Primary Vaccination Study With a Pneumococcal Conjugate Vaccine in Healthy Children 6 to 12wks of Age

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Mexico
GlaxoSmithKline

Completed

Primary Vaccination Study With GSK Biologicals' Pneumococcal Vaccine in Healthy Infants in Vietnam

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Vietnam
GlaxoSmithKline

Completed

Assess the Immunogenicity of GSK Biologicals' 10-valent Pneumococcal Conjugate Vaccine

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Germany
Pfizer

Completed

Nasopharyngeal Streptococcus Pneumoniae Carriage

Streptococcus Pneumoniae Infections

Taiwan
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Prevalence of Nasopharyngeal Carriage of Streptococcus Pneumoniae in Healthy Children of 12-18 Months in 6 Cities, China

Streptococcus Pneumoniae Infections

China
GlaxoSmithKline

Completed

Assessment of Antibody Persistence in Children Previously Vaccinated With Pneumococcal Conjugate Vaccine

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Poland
Centre Hospitalier Universitaire Dijon

Completed

Identification and Quantification of Immune Response Induced by Hyaluronidase and Other Factors of Virulence of Invasive Human Infections of Streptococcus Pneumoniae (Hyalo strepto)

Invasive Pneumococcic

France
University of Oxford

Completed

An Alternative Booster Vaccine Against Meningitis and Ear Infections

Invasive Streptococcus Pneumoniae Disease

United Kingdom
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of GlaxoSmithKline (GSK) Biologicals' Pneumococcal Vaccine (Synflorix™) When Administered to Children Who Are at an Increased Risk of Pneumococcal Infection

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Russian Federation, Poland
GlaxoSmithKline

Completed

Evaluate Safety and Immunogenicity of a Booster Dose of Pneumococcal Conjugate Vaccine in Preterm Born Infants.

Streptococcus Pneumoniae Vaccines | Infections, Streptococcal

Spain, Greece
UMC Utrecht
Netherlands: Ministry of Health, Welfare and Sports; Netherlands Vaccine Institute

Completed

Effect of Two Versus Three Pneumococcal Conjugate Vaccinations (MNOES)

Streptococcus Pneumoniae Infection
GlaxoSmithKline

Completed

Study to Evaluate the Response Rate to the Licensed Pneumovax 23™ in Elderly Population.

Streptococcus Pneumoniae Vaccines

Sweden
University of Colorado, Denver
Pfizer

Completed

Determination of the Utility of Pfizer's Pneumococcal Urine Antigen Test in Children 5 Years of Age or Younger With Community Acquired Pneumonia in Guatemala

Community-acquired Pneumonia | Streptococcus Pneumoniae Infection

Guatemala
Medical Corps, Israel Defense Force

Completed

Pharyngeal Carriage Rates and Genetic Typing of Group A Streptococcus and Streptococcus Pneumonia Among Israeli Military Basic Trainees

Group A Streptococcus | Streptococcus Pneumonia | Carriage
Arto Palmu
GlaxoSmithKline

Completed

Effects of Pneumococcal Vaccine on Nasopharyngeal Carriage

Nasopharyngeal Carriage of Streptococcus Pneumoniae

Finland
GlaxoSmithKline

Withdrawn

Post-marketing Safety Study of GlaxoSmithKline (GSK) Biologicals' Synflorix™ Vaccine, in Healthy Infants and Children in Sri Lanka

Immunisation Against Streptococcus Pneumoniae
University of Milan

Unknown

Longitudinal Pattern of Streptococcus Pneumoniae Nasopharyngeal Carriage and Antimicrobial Susceptibility in Healthy Children Aged Less Then 5 Years, in the Area of Milan and Surroundings, Lombardy, Italy.

Streptococcus Pneumoniae Nasopharyngeal Carriage

Italy
Azienda Ospedaliera di Lecco
IRCCS Ospedale San Raffaele

Not yet recruiting

Evaluation of Vaccination for Streptococcus Pneumoniae in Adults With an Episode of Invasive Pneumococcal Infection. (pVax)

Invasive Pneumococcal Infection
Walvax Biotechnology Co., Ltd.

Completed

Immunogenicity and Safety Study of the 13-valent Pneumococcal Polysaccharide Conjugate Vaccine in 2-71 Months Old Healthy Infants and Toddlers (the Youngest Could be 6 Weeks Old)

Diseases Caused by Streptococcus Pneumoniae Serotypes
Liverpool School of Tropical Medicine
Merck Sharp & Dohme LLC

Recruiting

Experimental Human Pneumococcal Challenge With SPN3 (Challenge3)

Streptococcus Pneumonia

United Kingdom
Liverpool School of Tropical Medicine
Pfizer

Recruiting

PREVENTING PNEUMOcoccal Disease Through Vaccination (Study 2) (Pneumo 2)

Streptococcus Pneumonia

United Kingdom
Sanofi Pasteur, a Sanofi Company

Completed

Study of an Investigational Pneumococcal Vaccine at Three Dose Levels in Healthy Adults

Pneumococcal Infections | Streptococcus Pneumoniae Infections | Pneumococcal Pneumonia

Switzerland
Sanofi

Completed

Study of Two Investigational Pneumococcal Vaccines in Healthy Adults

Pneumococcal Infections | Streptococcus Pneumoniae Infections | Pneumococcal Pneumonia

Switzerland
Radboud University Medical Center

Completed

A Controlled Human Pneumococcal Infection Model (PIM) Study (PIM)

Streptococcus Pneumoniae Infection

Netherlands
Centre Hospitalier Universitaire de Nīmes

Recruiting

Prevention of Pneumococcal Infections: Impact Collaborative Medico-pharmaceutical Care Structured to Improve Vaccination Coverage of Patients at Risk. (OPTIVACC)

Streptococcus Pneumoniae Infection

France
Sanofi Pasteur, a Sanofi Company

Completed

Study of Investigational Pneumococcal Vaccine in Healthy Adults, Toddlers and Infants

Pneumonia | Pneumococcal Infections | Streptococcus Pneumoniae Infections

Bangladesh
VA Office of Research and Development
Michael E. DeBakey VA Medical Center

Completed

Humoral Determinants of Immunity to Pneumococcal Infection

Pneumonia | Pneumococcal Infections | Infections, Streptococcus Pneumoniae

United States
Merck Sharp & Dohme LLC

Completed

Safety, Tolerability and Immunogenicity of V114 in Healthy Adults and Infants (V114-004)

Pneumococcal Infections | Streptococcus Pneumoniae Infection
Vabiotech
Vietstar Biomedical Research

Not yet recruiting

Assess the Safety and Immunogenicity of PNEUMOSIL® Vaccine in Healthy Vietnamese Children, 6 Weeks to 24 Months of Age (PNEUMOSIL)

Vaccine Preventable Disease | Streptococcus Pneumonia
GlaxoSmithKline

Completed

Primary Vaccination Study With a Pneumococcal Conjugate Vaccine in Healthy Children 6 to 10 Weeks of Age

Streptococcus Pneumoniae | Infections, Streptococcal

India
GlaxoSmithKline

Completed

Vaccination With GSK 1024850A in Children Primed With GSK 1024850A & Boosted With Pneumovax 23™

Streptococcus Pneumoniae | Infections, Streptococcal

Germany
University of Pittsburgh

Completed

Etiology of Community Acquired Pneumonia (CAP)

Streptococcus Pneumonia | Mycoplasma Pneumonia | Haemophilus Influencae | Chlamydia Pneumonia

United States
Boston Medical Center
Merck Sharp & Dohme LLC

Completed

Streptococcus Pneumonia: Effects of PCV13 on Pneumococcal Carriage

Nasopharyngeal Carriage of S. Pneumoniae

United States
GlaxoSmithKline

Completed

Evaluation of Effectiveness of GSK Biologicals' Pneumococcal Conjugate Vaccine 1024850A Against Invasive Disease (FinIP)

Streptococcus Pneumoniae | Infections, Streptococcal

Finland
International Medical University
Merck Sharp & Dohme LLC; Universiti Putra Malaysia; University of Southampton; International... and other collaborators

Recruiting

Pneumococcal Carriage and Serotype Distribution in Children With Otitis Media in Malaysia. (OM)

Otitis Media | Streptococcus Pneumonia

Malaysia
Mackay Memorial Hospital
Merck Sharp & Dohme LLC

Not yet recruiting

Epidemiology and Household Transmission of Streptococcus Pneumoniae and Respiratory Syncytial Virus

Respiratory Syncytial Virus Infections | Streptococcus Pneumoniae Infection
Sciensano
Merck Sharp & Dohme LLC; Pfizer; Universitaire Ziekenhuizen KU Leuven

Recruiting

Surveillance of Non-invasive Streptococcus Pneumoniae Infections in Belgium (STREPTO)

Pneumonia | Otitis Media | Sinusitis Bacterial

Belgium
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Severe Group A Streptococcus Infections in Paris, France, 2018-2023 (IGASI)

Invasive Group A Beta-Haemolytic Streptococcal Disease

France
Chinese University of Hong Kong

Recruiting

Evaluation of Streptococcus Pneumoniae Serotypes Prevalence Using a Urinary Kit

Community-acquired Pneumonia

Hong Kong
Novartis Vaccines

Completed

A Phase I, Randomized, Single-blind, Controlled, Single Center Study to Evaluate the Safety and Immunogenicity of a Dose Range of a Monovalent Glycoconjugate Antigen Vaccine of Group B Streptococcus in Healthy Women 18-40 Years of Age

Invasive Group B Streptococcus (GBS) Disease

Switzerland
Novartis Vaccines

Completed

A Phase I, Randomized, Single-blind, Controlled, Single Center Study to Evaluate the Safety and Immunogenicity of a Dose Range of Glycoconjugate Antigen Vaccine of Group B Streptococcus in Healthy Women 18- 40 Years of Age

Invasive Group B Streptococcus (GBS) Disease

Switzerland
Methodist Health System

Recruiting

Short Versus Long Duration of Therapy for Streptococcus Pneumoniae Bloodstream Infections

Streptococcus Pneumoniae

United States
Combioxin SA

Completed

Safety, Tolerability, Efficacy and Pharmacodynamics of CAL02 in Severe Pneumonia Caused by Streptococcus Pneumoniae

Pneumonia | Pneumococcal Infections

France, Belgium
Prof. Elizabeth Miller

Completed

Evaluating Vaccine Responses in Healthy Infants Receiving Their Routine Primary Immunisation According to the Accelerated United Kingdom Schedule at 2, 3 and 4 Months (P13UK)

Streptococcus Pneumoniae

United Kingdom
Public Health England

Completed

Immunogenicity of a Reduced Primary Schedule for Pneumococcal Conjugate Vaccine in UK Infants

Streptococcus Pneumoniae

Clinical Trials on Invasive Streptococcus Pneumoniae Disease

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