Clinical Trials on KIT Gene Mutation in United Kingdom
Total 896 results
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Abramson Cancer Center at Penn MedicineRecruiting
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Wake Forest University Health SciencesNational Center for Complementary and Integrative Health (NCCIH); University... and other collaboratorsCompletedFatty Acid-Gene InteractionsUnited States
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Pasithea Therapeutics Corp.RecruitingAdvanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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Ohio State University Comprehensive Cancer CenterImmunoGen, Inc.; Clovis Oncology, Inc.Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Folate Receptor Alpha Positive | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Recurrent Uterine Serous Carcinoma | Recurrent Uterine Carcinosarcoma | Platinum...United States
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Children's Healthcare of AtlantaEmory University; Brigham and Women's Hospital; University of California, San... and other collaboratorsWithdrawnPentalogy of Cantrell | Mutations in Non-muscle GenesUnited States
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Vanderbilt University Medical CenterRecruitingIdiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo | Healthy Individuals With no Cardiopulmonary DiseaseUnited States
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Boston Children's HospitalEunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsCompletedPTEN Gene Mutation | PTEN Hamartoma Tumor SyndromeUnited States
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Dana-Farber Cancer InstituteAbbVie; Pharmacyclics LLC.Active, not recruitingWaldenstrom Macroglobulinemia | MYD88 Gene MutationUnited States
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Dana-Farber Cancer InstituteNational Cancer Institute (NCI); Baylor College of Medicine; City of Hope Medical...RecruitingTP53 Gene Mutation | Li-Fraumeni Syndrome | Hereditary Cancer Syndrome | Mosaicism | Clonal HematopoiesisUnited States
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University of PittsburghNational Institute of Dental and Craniofacial Research (NIDCR); Kaiser PermanenteCompletedPit-and-Fissure SealantsUnited States
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BiogenRecruitingAmyotrophic Lateral Sclerosis Associated With a SOD1 Gene MutationUnited States, Canada, Spain, Australia, Germany, Italy, Japan, Korea, Republic of, United Kingdom, Belgium, Brazil, France, Poland, Sweden
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Scripps HealthJ. Craig Venter InstituteCompletedLi-Fraumeni Syndrome | Hereditary Cancer Syndromes | TP53 Gene Germline Mutation CarrierUnited States
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Faeth TherapeuticsActive, not recruitingAdvanced Solid Tumor | PIK3CA Mutation | PTEN Loss of Function MutationUnited States
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Pathway GenomicsCompletedNeoplasms | MutationUnited States
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University of WashingtonNational Cancer Institute (NCI)TerminatedRecurrent Non-Small Cell Lung Carcinoma | EGFR Activating Mutation | Stage IV Non-Small Cell Lung Cancer AJCC v7 | ALK Gene Translocation | Stage IIIB Non-Small Cell Lung Cancer AJCC v7 | ROS1 Gene TranslocationUnited States
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Royal Marsden NHS Foundation TrustRecruitingLynch Syndrome | Familial Adenomatous Polyposis | Hereditary Diffuse Gastric Cancer | Peutz-Jeghers Syndrome | Cowden Syndrome | Li Fraumeni Syndrome | MutYH-associated Polyposis | SMAD4 Gene MutationUnited Kingdom
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University of PennsylvaniaInovio PharmaceuticalsRecruiting
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Memorial Sloan Kettering Cancer CenterCompletedNon Small Cell Lung Cancer | KRAS Gene MutationUnited States
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Merrimack PharmaceuticalsCompletedHER-2 Gene AmplificationUnited States
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University of California, San FranciscoThe Bluefield Project to Cure Frontotemporal DementiaCompletedProgranulin Mutation CarriersUnited States
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Weill Medical College of Cornell UniversityCompletedBreast Cancer | Gynecologic Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditionsUnited States
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Aspira Women's HealthTerminatedHereditary Breast and Ovarian Cancer | Adnexal Mass | Germline BRCA1 Gene Mutation | Germline BRCA2 Gene MutationUnited States
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC... and other conditionsUnited States
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University of Texas Southwestern Medical CenterNational Heart, Lung, and Blood Institute (NHLBI); Columbia University; The Cleveland... and other collaboratorsRecruitingAmyloidosis, Familial | Amyloidosis, Hereditary | Amyloidosis Cardiac | Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Transthyretin Gene MutationUnited States
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Case Comprehensive Cancer CenterRecruitingPositive FIT or Stool DNA Testing Follow upUnited States
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Johnson & Johnson Vision Care, Inc.CompletedContact Lens Base Curve (BC) Fit and ComfortUnited States
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University of EdinburghNHS LothianCompleted
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Sidney Kimmel Comprehensive Cancer Center at Johns...Merck Sharp & Dohme LLCActive, not recruitingHigh Tumor Mutation Burden | High TMB (Tumor Mutation Burden) | MSS (Microsatellite Stable)United States
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TriHealth Inc.TriHealth Cancer Institute; TriHealth Surgical Institute; TriHealth Ultrasound... and other collaboratorsWithdrawnMelanoma (Skin) | Tumor Skin | BRAF Gene Mutation | Melanoma Stage IIIb-IVM1a | Metastasis SkinUnited States
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Escape Bio, Inc.Momentum Pharma; Science 37TerminatedPatients With Parkinson's Disease (PD) Caused by the p.Gly2019Ser (G2019S) Pathogenic Mutation of the Leucine-Rich Repeat Kinase 2 (LRRK2) GeneUnited States
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RWJ Barnabas Health at Jersey City Medical CenterUnknownLynch Syndrome | Endometrial Cancer | Somatic Mutation | Cancer Gene MutationUnited States
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Hoffmann-La RocheNo longer availableCancers With NTRK, ROS1, or ALK Gene FusionsUnited States
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Blueprint Medicines CorporationTerminatedNeoplasms | Respiratory Tract Diseases | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | Non Small Cell Lung... and other conditionsUnited States
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NYU Langone HealthWithdrawnBreast Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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Iambic Therapeutics, IncRecruiting
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Taiho Oncology, Inc.Active, not recruitingAdvanced Cholangiocarcinoma | FGFR2 Gene RearrangementsUnited States, Spain, United Kingdom, Australia, Taiwan, Italy, France, Korea, Republic of, Belgium, Japan, Thailand, Germany, Brazil, Peru, Portugal, Argentina, Hong Kong, Mexico, Netherlands, Poland
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University of ChicagoRecruitingBreast Cancer | Head and Neck Cancer | Gastrointestinal Cancer | Dihydropyrimidine Dehydrogenase Deficiency | UGT1A1 Gene MutationUnited States
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National Cancer Institute (NCI)CompletedTherapy-Related Acute Myeloid Leukemia | Acute Myeloid Leukemia With FLT3/ITD Mutation | FLT3 Gene Mutation | Acute Promyelocytic Leukemia With PML-RARA | Acute Myeloid Leukemia With Inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11 | Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1United States
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Massachusetts General HospitalCompletedBreast Cancer | BRCA1 Mutation | BRCA2 MutationUnited States
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European Organisation for Research and Treatment...Active, not recruitingEGFR Mutation Positive Non Small Cell Lung CancerUnited Kingdom
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Massachusetts General HospitalAgios Pharmaceuticals, Inc.CompletedIDH1 Mutation Myeloid NeoplasmsUnited States
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NHS Greater Glasgow and ClydeUnknownNeuropathic Pain | Lower Limb AmputationUnited Kingdom
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Roswell Park Cancer InstituteCelgeneWithdrawnRecurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | IDH2 Gene Mutation | Blasts Under 5 Percent of Peripheral Blood White Cells | Bone Marrow Blasts Decreased by 50 Percent or More Compared to Pretreatment LevelUnited States
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Shirley Ryan AbilityLabUniversity of AlbertaRecruitingAmputation | Amputation; Traumatic, Hand | Amputation, Traumatic | Amputation; Traumatic, LimbUnited States
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Peloton Therapeutics, Inc., a subsidiary of Merck...Active, not recruitingVHL - Von Hippel-Lindau Syndrome | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL-Associated Renal Cell Carcinoma | VHL-Associated Clear Cell Renal Cell CarcinomaUnited States, Denmark, United Kingdom, France
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SwanBio Therapeutics, Inc.Active, not recruitingAMN | AMN Gene Mutation | X-ALDUnited States, Netherlands, Germany
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Liberating Technologies, Inc.Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsCompletedAmputation | Prosthesis User | Amputation; Traumatic, Hand | Amputation, CongenitalUnited States
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ABM Therapeutics CorporationRecruitingAdvanced Solid Tumor | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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Georgetown UniversityImmune System Key LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsUnited States