Clinical Trials on KRAS Gene Mutation in Canada
Total 112 results
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University Health Network, TorontoBayer; AstraZeneca; Amgen; Applied Health Research Centre; Takeda Canada, Inc.; Programs...RecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedBRCA1 Gene Mutation | BRCA2 Gene Mutation | Recurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7 | BRIP1 Gene Mutation | PALB2 Gene Mutation | ATM Gene Mutation | ATR Gene Mutation | CHEK2 Gene Mutation | NBN Gene Mutation | RAD51 Gene Mutation | CHEK1 Gene Mutation | FANCA Gene... and other conditionsUnited States, Canada
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University Health Network, TorontoAbbVie; CelgeneTerminatedAcute Myeloid Leukemia | Relapsed Cancer | Refractory Cancer | IDH2 Gene MutationCanada
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Southwest Oncology GroupNational Cancer Institute (NCI)CompletedRecurrent Squamous Cell Lung Carcinoma | Stage IV Squamous Cell Lung Carcinoma AJCC v7 | FGFR1 Gene Amplification | FGFR2 Gene Amplification | FGFR2 Gene Mutation | FGFR3 Gene Mutation | FGFR1 Gene Mutation | FGFR3 Gene AmplificationUnited States, Canada
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Women's College HospitalCanadian Institutes of Health Research (CIHR); London Health Sciences Centre; H. Lee Moffitt Cancer Center and Research Institute and other collaboratorsUnknownBreast Cancer | Ovarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene MutationCanada
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AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.Active, not recruitingBreast Cancer Metastatic | BRCA 1 Gene Mutation | BRCA 2 Gene MutationItaly, Spain, United States, Czechia, Romania, France, Korea, Republic of, United Kingdom, Hungary, Japan, Peru, Poland, Russian Federation, Turkey, China, Taiwan, Bulgaria, Switzerland, Mexico
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University Health Network, TorontoCompletedColorectal Cancer | KRAS Wildtype | NRAS Wildtype | BRAF WildtypeCanada
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QED Therapeutics, Inc.Helsinn Healthcare SATerminatedFGFR2 Gene Mutation | Advanced CholangiocarcinomaKorea, Republic of, United States, Belgium, Spain, Taiwan, China, United Kingdom, France, Canada, Germany, Thailand, Italy, Portugal, Australia, Puerto Rico
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Day One Biopharmaceuticals, Inc.RecruitingMelanoma | Colorectal Cancer | Solid Tumor | Non Small Cell Lung Cancer | Bladder Cancer | Thyroid Cancer, Papillary | Pilocytic Astrocytoma | Bladder Urothelial Carcinoma | Non-Small Cell Adenocarcinoma | MEK Mutation | RAS Mutation | Pancreatic Acinar Carcinoma | RAF Mutation | CRAF Gene Amplification | RAF1 Gene Amplification and other conditionsUnited States, Canada, Korea, Republic of, Spain, Australia, Belgium, France
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AmgenRecruitingAdvanced Solid Tumors | Kirsten Rat Sarcoma (KRAS) pG12C MutationUnited States, Italy, Taiwan, Spain, United Kingdom, Australia, Austria, Germany, Belgium, Japan, Netherlands, Korea, Republic of, Canada
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National Cancer Institute (NCI)Glaxosmithkline Biologicals S.A.TerminatedRenal Failure | Solid Neoplasm | BRAF Gene Mutation | Hepatic ComplicationUnited States, Canada
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Laval UniversityCompleted
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Rhythm Pharmaceuticals, Inc.CompletedPro-opiomelanocortin (POMC), Proprotein Convertase Subtilisin/Kexin Type 1 (PCSK1) and Leptin Receptor (LepR) Gene MutationsUnited States, Israel, Canada, Germany, Greece, Italy, Portugal
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University Health Network, TorontoPfizerRecruitingNon-squamous Non-small-cell Lung Cancer | Stage IV Non-small Cell Lung Cancer | ROS1 Gene Rearrangement | MET Activating Mutation | MET AmplificationCanada
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Tesaro, Inc.European Organisation for Research and Treatment of Cancer - EORTC; Breast... and other collaboratorsTerminatedOvarian Neoplasms | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Neoplasms, Breast | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Carcinoma of BreastUnited States, Spain, Belgium, Israel, United Kingdom, Italy, Poland, Canada, Hungary, Netherlands, France, Portugal, Greece, Iceland
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University Health Network, TorontoActive, not recruitingMutation | Hereditary Cancer Syndrome | High-Risk | Germline MutationCanada
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Centre hospitalier de l'Université de Montréal...RecruitingAmputation; Traumatic, HandCanada
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University Health Network, TorontoSuspendedBreast Cancer | Breast Diseases | Genetic Predisposition to Disease | Surgery | Surgery--Complications | BRCA1 Mutation | BRCA2 MutationCanada
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Centre hospitalier de l'Université de Montréal...RecruitingAmputation; Traumatic, HandCanada
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AmgenActive, not recruitingKRAS p.G12C Mutant Advanced Solid TumorsUnited States, France, Canada, Spain, Belgium, Korea, Republic of, Austria, Australia, Hungary, Greece, Germany, Japan, Romania, Switzerland, Brazil, Portugal
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PfizerTerminatedDilated Cardiomyopathy | Lamin A/C Gene MutationUnited States, Spain, Canada, Belgium, Italy, Argentina, Mexico, Netherlands, Norway, United Kingdom
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Fundación GECPRecruitingNon Small Cell Lung Cancer | EGFR Gene MutationSpain
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Sunnybrook Health Sciences CentreCompleted
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Regeneron PharmaceuticalsRecruitingCongenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)Spain, United Kingdom, United States
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Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | EGF-R Positive Non-Small Cell Lung... and other conditionsUnited States, Canada, Taiwan, Korea, Republic of, Singapore, Japan, United Kingdom, France, Netherlands, Spain
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Sunnybrook Health Sciences CentreCompleted
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University of British ColumbiaCompleted
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Institute for Clinical Evaluative SciencesCanadian Institutes of Health Research (CIHR); Ontario Agency for Health Protection... and other collaboratorsCompletedAntibiotic Initiation | Antibiotic DurationCanada
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Infinite Biomedical TechnologiesUnited States Department of Defense; University of AlbertaRecruitingAmputation | Upper LimbCanada
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Sunnybrook Health Sciences CentreRecruitingAmputation | Mental Health | Psychotherapy, GroupCanada
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Institute for Clinical Evaluative SciencesCanadian Institutes of Health Research (CIHR); Ontario Agency for Health Protection... and other collaboratorsCompletedAntibiotic Initiation | Antibiotic DurationCanada
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University of British ColumbiaCompletedBelow Knee AmputationCanada
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Medical Creations, Inc.CompletedAmputation | Prosthesis UserUnited States, Canada
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University Health Network, TorontoRecruitingGlioma | Solid Tumor | Cholangiocarcinoma | IDH MutationCanada
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University Health Network, TorontoCompletedSkull Pin Insertion | Short Duration AnalgesiaCanada
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Gaziler Physical Medicine and Rehabilitation Education...CompletedTraumatic Amputation of Lower Extremity | Cartilage DegenerationTurkey
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Population Health Research InstituteCanadian Institutes of Health Research (CIHR)Terminated
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BiogenRecruitingAmyotrophic Lateral Sclerosis Associated With a SOD1 Gene MutationUnited States, Canada, Spain, Australia, Germany, Italy, Japan, Korea, Republic of, United Kingdom, Belgium, Brazil, France, Poland, Sweden
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Maisonneuve-Rosemont HospitalActive, not recruitingPersonal Satisfaction | Genu VarumCanada
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University of British ColumbiaCompletedOlder Adults | Lower Limb AmputationCanada
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Montreal General HospitalCompletedBrachial Plexus Block DurationCanada, Thailand
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University of British ColumbiaVancouver Coastal Health Research Institute; GF Strong Rehabilitation CentreCompletedUnilateral Trans Tibial/Femoral Lower Limb AmputationCanada
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Pacific Parkinson's Research CentreUniversity of British Columbia; Oregon Health and Science University; University... and other collaboratorsRecruitingParkinson Disease | Gaucher Disease | GBA Gene MutationUnited States, Canada
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PfizerCompletedSolid Tumors Harboring a BRAF V600 MutationUnited States, France, Italy, Singapore, Australia, Spain, Switzerland, Canada, Belgium
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Blueprint Medicines CorporationActive, not recruitingNeoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditionsUnited States, Canada, Korea, Republic of, Japan, Taiwan
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University of SaskatchewanUniversity of ManitobaCompletedAmputation | Motor Activity | Phantom Limb | Amputation StumpCanada
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BayerRecruitingLocally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene FusionUnited States, Austria, Denmark, Germany, Italy, Norway, Spain, United Kingdom, Brazil, Russian Federation, Switzerland, Taiwan, Canada, China, Australia, Greece, Belgium, Sweden, Korea, Republic of, France, Argentina, Finland, Ireland and more
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University of AlbertaCompletedPediatric ALL | Congenital Heart Disease | ERASCanada
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AmgenCompleted
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PfizerCompletedTransthyretin Amyloidosis | Transthyretin Gene MutationsUnited States, France, Spain, Taiwan, Israel, Korea, Republic of, Denmark, Canada, Netherlands, Japan, Sweden, Brazil, Mexico, Argentina, Portugal, Belgium, Bulgaria, Cyprus, Germany, Italy, Malaysia, Romania, Saudi Arabia, Turkey, United...