Clinical Trials on KRAS Mutated Colorectal Cancer
Total 6612 results
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Lupin Ltd.CompletedA Study of LNP3794 in Subjects With NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsNRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsUnited Kingdom, Netherlands, Belgium
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Revolution Medicines, Inc.RecruitingNon-Small Cell Lung Cancer, NSCLC | KRAS, NRAS, HRAS-mutated NSCLC | KRAS G12C-mutated Solid Tumors, Lung Cancer | Lung Cancer Stage IV, Advanced Solid Tumor, CancerUnited States
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Elicio TherapeuticsRecruitingColorectal Cancer | Pancreatic Ductal Adenocarcinoma | KRAS G12D | KRAS G12R | NRAS G12D | NRAS G12R | KRAS G12V | KRAS G12C | KRAS G12A | KRAS G12S | KRAS G13D | NRAS G12V | NRAS G12C | NRAS G12SUnited States
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Institut du Cancer de Montpellier - Val d'AurelleCompletedMetastatic Colorectal Cancer Patients With KRAS Mutated TumorsFrance
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National Cancer Institute, NaplesRecruitingRas-mutated Metastatic Colorectal CancerItaly
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Cardiff OncologyPfizerRecruitingMetastatic Colorectal Cancer | CRC | KRAS/NRAS MutationUnited States
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University of UtahTerminatedKRAS and NRAS Wild-type Colorectal CancerUnited States
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European Organisation for Research and Treatment...SanofiWithdrawnColorectal Cancer Metastatic | Liver Metastases | KRAS Mutated Colorectal Cancer
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University Health Network, TorontoCompletedColorectal Cancer | KRAS Wildtype | NRAS Wildtype | BRAF WildtypeCanada
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Henan Cancer HospitalCompletedWild-type KRAS,NRAS and BRAF V600E Metastatic Colorectal Cancer
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Cancer Institute and Hospital, Chinese Academy...RecruitingBevacizumab | Capecitabine | Metastatic Colorectal Cancer (mCRC) | Oxaliplatin | Tislelizumab | First-Line | MSS/pMMR | RAS-mutatedChina
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University Health Network, TorontoBayer; AstraZeneca; Amgen; AnHeart Therapeutics Inc.; Applied Health Research Centre and other collaboratorsRecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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N.N. Petrov National Medical Research Center of...RecruitingMelanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene MutationRussian Federation
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Karen-Lise Garm SpindlerCompletedColorectal Cancer Metastatic | KRAS Gene Mutation | Circulating Tumor DNA | BRAF Gene Mutation | NRAS Gene Mutation | Epidermal Growth Factor Receptor InhibitorDenmark
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Blokhin's Russian Cancer Research CenterRecruitingColorectal Cancer Metastatic | Brain Metastases, Adult | HER2 Gene Mutation | MSI | BRAF Gene Mutation | Ras (KRAS or NRAS) Gene MutationRussian Federation
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC... and other conditionsUnited States
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EPS CorporationCompletedLiver Only Metastasis From KRAS Exon 2 Wild Type (Under Protocol 1.0-1.2 Edition) and RAS Wild Type (Under Protocol 2.0 Edition) Colorectal CancerJapan
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The First Affiliated Hospital of Zhengzhou UniversityBeiGene; Jiangsu Hengrui Pharmaceutical Co., Ltd.; RemeGen Co., Ltd.Not yet recruitingHER2-positive or Mutated Advanced Colorectal Cancer
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M.D. Anderson Cancer CenterNot yet recruitingMetastatic Colorectal Cancer | KRAS G12C MutationsUnited States
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University of UtahPfizerCompletedAdvanced KRAS Positive Metastatic Colorectal CancerUnited States
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Oncolytics BiotechMontefiore Medical CenterCompletedKRAS Mutant Metastatic Colorectal CancerUnited States
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Sierra Oncology, Inc.TerminatedRelapsed Metastatic KRAS-Mutated Non-Small Cell Lung CancerUnited States
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Shanghai Pharmaceuticals Holding Co., LtdNot yet recruitingBiliary Tract or Colorectal Cancer With Her2-positive/MutatedChina
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Hunan Province Tumor HospitalRecruitingNon-small Cell Lung Cancer | KRAS G12D | KRAS G12R | KRAS G12V | KRAS G12C | KRAS G12Y | KRAS G13NChina
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Cardiff OncologyCompletedMetastatic Colorectal Cancer | KRAS Gene MutationUnited States
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Cardiff OncologyNo longer availableMetastatic Colorectal Cancer | KRAS Gene Mutation
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Frontier Medicines CorporationRecruitingColorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Unresectable Solid Tumor | KRAS G12C | Advanced Solid Tumors With KRAS G12C MutationsUnited States
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Inspirna, Inc.RecruitingGastrointestinal Neoplasms | Colorectal Neoplasms | Gastric Cancer | Colorectal Cancer | Colorectal Cancer Metastatic | Gastrointestinal Cancer | Colorectal Carcinoma | CRC | KRAS Mutation-Related Tumors | Gastric NeoplasmUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); Genentech, Inc.Active, not recruitingStage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Malignant Solid Neoplasm | Unresectable Solid Neoplasm | BRAF NP_004324.2:p.V600X | KRAS wt AlleleUnited States
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West China HospitalRecruitingBRAF V600E-mutated /MSS Metastatic Colorectal Cancer | Vemurafenib (BRAFi) Plus Cetuximab (EGFRi) Combined With PD-1 Monoclonal AntibodyChina
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xCuresCancer CommonsAvailableExpanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesMelanoma | Head and Neck Cancer | Glioblastoma | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Small Bowel Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Cholangiocarcinoma | Bladder Cancer | Thyroid Cancer | ERK Mutation | MAPK Gene Mutation | KRAS Activating... and other conditionsUnited States
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European Organisation for Research and Treatment...Roche Pharma AG; AmgenTerminatedColorectal Cancer Metastatic | Liver Metastases | KRAS Wild Type Colorectal CancerFrance, Belgium, Austria, Netherlands, Spain, Switzerland
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Vanderbilt-Ingram Cancer CenterNational Cancer Institute (NCI); Calithera Biosciences, IncActive, not recruitingMetastatic Colorectal Cancer | Colorectal Cancer | RAS Wild Type Colorectal Cancer | Refractory Colorectal CancerUnited States
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The Netherlands Cancer InstituteLustgarten FoundationRecruitingColorectal Cancer | Pancreatic Cancer | Non-small Cell Lung Cancer | KRAS Mutation-Related TumorsNetherlands
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingEGFR NP_005219.2:p.S492R | KRAS Gene Mutation | MAP2K1 Gene Mutation | Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7United States
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MapKure, LLCRecruitingColorectal Cancer | Pancreatic Ductal Cancer | Advanced or Metastatic RAS Mutant Colorectal and Pancreatic Ductal CancersAustralia, United States
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M.D. Anderson Cancer CenterActive, not recruitingStage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | RAS Wild TypeUnited States
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Providence Health & ServicesAvailableKRAS G12V Mutant Advanced Epithelial Cancers
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Vanderbilt University Medical CenterEdwards LifesciencesCompletedColorectal Surgery | Perioperative Care | Quality Improvement | ERASUnited States
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AmgenActive, not recruitingKRAS p, G12c Mutated /Advanced Metastatic NSCLCFinland, United States, Canada, Belgium, Spain, Korea, Republic of, Netherlands, United Kingdom, Australia, Denmark, Hungary, Sweden, Taiwan, Greece, Russian Federation, Switzerland, France, Italy, Japan, Poland, Brazil, Germany, Po...
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University of Rome Tor VergataCompletedColon Cancer | ERAS | T4 Colorectal Cancer | Fast Track Protocol
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Novartis PharmaceuticalsActive, not recruitingLocally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutationSpain, Italy, Austria, Netherlands, United Kingdom, Thailand, France, Belgium, China, Germany, Greece, Argentina, Turkey, Malaysia, Portugal, Brazil, United States, Hungary, India
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)CompletedStage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | RAS Wild TypeUnited States
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Azienda Unità Sanitaria Locale Reggio EmiliaIstituto Di Ricerche Farmacologiche Mario Negri; Istituto Nazionale Tumori...RecruitingMetastatic Colorectal Cancer | Colorectal Cancer | RAS MutationItaly
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PfizerBristol-Myers SquibbCompletedMSS | RAS-mutant Colorectal CancerUnited States, Spain, Belgium, United Kingdom, Netherlands
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University of Southern CaliforniaNational Cancer Institute (NCI); AmgenTerminatedStage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | RAS Wild Type | Stage III Colorectal Cancer AJCC v7 | Stage IIIA Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer...United States
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Fudan UniversityRecruitingMetastatic Colorectal Cancer | Microsatellite Stable Colorectal Carcinoma | RAS Mutation | CadonilimabChina
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Tianshu LiuUnknownIncurable Colorectal Cancer | RAS-wild-typeChina
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Beijing HospitalBethune Charitable FoundationRecruitingICE Study: Combination of Irinotecan Plus Cetuximab and Envafolimab as a Rechallenge Regimen in mCRCMetastatic Colorectal Cancer | MSS | RAS MutationChina
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iOMEDICO AGAmgenCompletedMetastatic Colorectal Cancer | RAS Wild-typeGermany