Clinical Trials on KRAS G12C-mutated Solid Tumors, Lung Cancer
Total 2049 results
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Elicio TherapeuticsRecruitingColorectal Cancer | Pancreatic Ductal Adenocarcinoma | KRAS G12D | KRAS G12R | NRAS G12D | NRAS G12R | KRAS G12V | KRAS G12C | KRAS G12A | KRAS G12S | KRAS G13D | NRAS G12V | NRAS G12C | NRAS G12SUnited States
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Chinese PLA General HospitalZhejiang UniversityRecruitingSolid Tumor, Adult | KRAS G12D | EphA2 Overexpression | KRAS G12V | KRAS G12CChina
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Revolution Medicines, Inc.RecruitingNon-Small Cell Lung Cancer, NSCLC | KRAS, NRAS, HRAS-mutated NSCLC | KRAS G12C-mutated Solid Tumors, Lung Cancer | Lung Cancer Stage IV, Advanced Solid Tumor, CancerUnited States
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Hunan Province Tumor HospitalRecruitingNon-small Cell Lung Cancer | KRAS G12D | KRAS G12R | KRAS G12V | KRAS G12C | KRAS G12Y | KRAS G13NChina
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Lupin Ltd.CompletedA Study of LNP3794 in Subjects With NRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsNRAS/KRAS Mutated Advanced or Metastatic Refractory Solid TumorsUnited Kingdom, Netherlands, Belgium
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Frontier Medicines CorporationRecruitingColorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Unresectable Solid Tumor | KRAS G12C | Advanced Solid Tumors With KRAS G12C MutationsUnited States
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Suzhou Genhouse Bio Co., Ltd.Zhejiang Cancer HospitalNot yet recruitingKRAS G12C Mutant Solid Tumors
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Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingKRAS G12C Mutant Advanced Solid TumorsChina
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Jiangsu HengRui Medicine Co., Ltd.Not yet recruitingAdvanced KRAS G12D Mutant Solid TumorsChina
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BeBetter Med IncXiangya Hospital of Central South UniversityRecruitingAdvanced or Metastatic Solid Tumor | KRAS G12C MutationChina
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Jiangsu HengRui Medicine Co., Ltd.RecruitingAdvanced KRAS G12D Mutant Solid TumorsChina
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Georgetown UniversityImmune System Key LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsUnited States
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Suzhou Zelgen Biopharmaceuticals Co.,LtdRecruitingSolid Tumor | KRAS Mutation-Related TumorsChina
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Affini-T Therapeutics, Inc.RecruitingColorectal Cancer | Non-Small Cell Lung Cancer | Solid Tumor | Pancreatic Ductal Adenocarcinoma | KRAS G12VUnited States
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University Health Network, TorontoBayer; AstraZeneca; Amgen; AnHeart Therapeutics Inc.; Applied Health Research Centre and other collaboratorsRecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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AmgenActive, not recruitingKRAS p, G12c Mutated /Advanced Metastatic NSCLCFinland, United States, Canada, Belgium, Spain, Korea, Republic of, Netherlands, United Kingdom, Australia, Denmark, Hungary, Sweden, Taiwan, Greece, Russian Federation, Switzerland, France, Italy, Japan, Poland, Brazil, Germany, Po...
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Providence Health & ServicesAvailableKRAS G12V Mutant Advanced Epithelial Cancers
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Turning Point Therapeutics, Inc.TerminatedAdvanced Solid Tumor | Metastatic Solid Tumor | KRAS Mutation-Related TumorsUnited States
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS MutationSpain, United Kingdom, United States, Belgium
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Nested Therapeutics, IncRecruitingGlioma | Melanoma | NSCLC | Oncology | Solid Tumor, Adult | MEK Mutation | RAF Gene Mutation | Ras (KRAS or NRAS) Gene Mutation | MAPK Pathway Gene MutationUnited States, Australia
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Boehringer IngelheimCompletedSolid Tumors, KRAS MutationJapan
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Novartis PharmaceuticalsActive, not recruitingLocally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutationSpain, Italy, Austria, Netherlands, United Kingdom, Germany, Thailand, France, Belgium, China, Argentina, Greece, Turkey, Malaysia, Portugal, Hungary, Brazil, United States, India
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Fore BiotherapeuticsActive, not recruitingAdvanced Unresectable Solid Tumors | BRAF-mutated TumorsUnited States
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AmgenRecruitingAdvanced Solid Tumors | Kirsten Rat Sarcoma (KRAS) pG12C MutationUnited States, Italy, Taiwan, Spain, United Kingdom, Australia, Austria, Germany, Belgium, Japan, Netherlands, Korea, Republic of, Canada
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS Mutation; SOS1United States, Netherlands, Germany
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Black Diamond Therapeutics, Inc.RecruitingMelanoma | Colorectal Cancer | NSCLC | Solid Tumor | Metastatic Lung Cancer | Metastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Non-small Cell Lung Cancer | Histiocytosis | Melanoma (Skin) | Recurrent Melanoma | Thyroid Carcinoma | Thyroid Cancer | Brain Metastases | Recurrent Histiocytic and Dendritic... and other conditionsUnited States
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Calithera Biosciences, IncCompletedNSCLC | Solid Tumors | KRAS Gene Mutation | CRCUnited States
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GeneQuantum Healthcare (Suzhou) Co., Ltd.RecruitingHER2 Expressing or Mutated Advanced Malignant Solid TumorsChina
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AmgenActive, not recruitingKRAS p.G12C Mutant Advanced Solid TumorsUnited States, France, Canada, Spain, Belgium, Korea, Republic of, Austria, Australia, Hungary, Greece, Germany, Japan, Romania, Switzerland, Brazil, Portugal
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Boehringer IngelheimRecruitingSolid Tumor, KRAS MutationUnited States, Taiwan, Japan
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Boehringer IngelheimCompleted
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Elicio TherapeuticsActive, not recruitingColorectal Cancer | Ovarian Cancer | Cholangiocarcinoma | Bile Duct Cancer | Non-small Cell Lung Cancer | Pancreatic Ductal Adenocarcinoma | Minimal Residual Disease | Gallbladder Carcinoma | KRAS G12D | KRAS G12R | NRAS G12D | NRAS G12RUnited States
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Institut du Cancer de Montpellier - Val d'AurelleCompletedMetastatic Colorectal Cancer Patients With KRAS Mutated TumorsFrance
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AmgenActive, not recruitingAdvanced/Metastatic Solid Tumors With KRAS p.G12C MutationTaiwan, Hong Kong
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NYU Langone HealthWithdrawnAdvanced Non-small Cell Lung Cancer With KRAS G12C MutationUnited States
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Novartis PharmaceuticalsRecruitingCarcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Colorectal Cancer | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Carcinoma, Non-Small Cell Lung | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal | Non-Small Cell Lung Carcinoma | KRAS G12C Mutant Solid TumorsKorea, Republic of, Spain, Belgium, United States, France, Germany, Italy, Singapore
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N.N. Petrov National Medical Research Center of...RecruitingMelanoma | Lung Cancer | Pancreas Cancer | Refractory Cancer | Colorectal Cancer Recurrent | RAS Mutation | Ras (Kras or Nras) Gene MutationRussian Federation
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Novartis PharmaceuticalsRecruitingCarcinoma, Non-Small-Cell Lung | Lung Cancer | Neoplasms, Lung | Pulmonary Neoplasms | Neoplasms, Pulmonary | Pulmonary Cancer | Cancer of Lung | Cancer of the Lung | KRAS G12C Mutant Solid Tumors | Carcinoma, ColorectalUnited States, Japan, Australia, Germany, Italy, Spain, Canada, Denmark, Korea, Republic of, Taiwan, Belgium, Hong Kong, China, France, Singapore, Netherlands
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Sierra Oncology, Inc.TerminatedRelapsed Metastatic KRAS-Mutated Non-Small Cell Lung CancerUnited States
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ETOP IBCSG Partners FoundationAmgen; Eisai Inc.WithdrawnMetastatic Non Small Cell Lung Cancer | KRAS G12CSpain, Switzerland, Austria, Germany
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NYU Langone HealthRecruitingAdvanced Non-small Cell Lung Cancer With KRAS G12C MutationUnited States
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M.D. Anderson Cancer CenterNot yet recruitingMetastatic Colorectal Cancer | KRAS G12C MutationsUnited States
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AstraZenecaCompletedRefractory Solid Tumors | Cancer TumorUnited States
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Immatics US, Inc.CompletedCancer | Solid Tumor | Refractory Solid Tumors | Recurrent Solid TumorsUnited States, Germany
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Dana-Farber Cancer InstituteCompletedSolid Tumors | KRAS Mutant Non-Small Cell Lung CancerUnited States
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Novartis PharmaceuticalsNantCell, Inc.TerminatedPIK3CA Mutated Advanced Solid Tumors | PIK3CA Amplified Advanced Solid TumorsSpain, Belgium, United States, Canada
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TheRas, Inc., d/b/a BridgeBio Oncology TherapeuticsRecruitingNSCLC | Metastatic Lung Cancer | Non-small Cell Lung Cancer | Advanced Lung Carcinoma | Metastatic Non-Small Cell Lung Cancer | KRAS G12CUnited States, Australia
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Pamela MunsterQuantumLeap Healthcare CollaborativeTerminatedTriple Negative Metastatic Breast Cancer | BRCA-mutated Solid TumorUnited States
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Ikena OncologyRecruitingColorectal Cancer | Pancreatic Cancer | Thyroid Carcinoma | Solid Tumor, Adult | Malignant Melanoma | Non-Small Cell Lung Carcinoma | BRAF Gene Mutation | Gliomas, Malignant | Ras (Kras or Nras) Gene Mutation | CRAF Gene MutationUnited States
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Keystone Nano, IncNational Cancer Institute (NCI); National Institutes of Health (NIH)CompletedCarcinoma | Cancer | Solid Tumors | TumorUnited States