Clinical Trials on Kidney Impairment in Czechia

Total 311 results

Idorsia Pharmaceuticals Ltd.

Completed

A Study to Evaluate ACT-132577 in Healthy Subjects and in People With Severe Kidney Disease

Healthy Subjects | Severe Renal Impairment

Czechia
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
Novartis Pharmaceuticals

Completed

Pharmacokinetic Study of Buparlisib in Subjects With Renal Impairment.

Renal Impairment

Czechia, Germany, Romania, Bulgaria
Charles University, Czech Republic

Recruiting

The Role of Endothelial Glycocalyx in Kidney Transplantation

Kidney Transplantation

Czechia
Takeda

Completed

A Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the Pharmacokinetics (PK) of a Single Intravenous (IV) TAK-954

Renal Impairment | Healthy Volunteers

Czechia, Hungary
Bristol-Myers Squibb

Completed

A Study to Assess the Safety of Experimental Medication BMS986165 in Participants With Normal Kidney Function and Participants With Mild to End-Stage Kidney Disease.

Renal Impairment | Healthy Volunteer

United States, Czechia, Hungary, Poland
Novartis

Completed

Effect of Severe Renal Impairment on Pharmacokinetics and Metabolism of a Single Administration of Licarbazepine

Healthy

Czech Republic
Mitsubishi Tanabe Pharma Corporation

Completed

PK Study in Subjects With Severe Hepatic Impairment (MCI-186-E05 HP)

Healthy | Severe Hepatic Impairment

Czechia, Hungary, Slovakia
GlaxoSmithKline

Completed

Study to Assess the Safety and PK of GSK573719 and GSK573719/GW642444(VI) Combination in Healthy Subjects and Subjects With Severe Renal Impairment

Pulmonary Disease, Chronic Obstructive

Czechia, Hungary
FORUM Pharmaceuticals Inc
PRA Health Sciences

Completed

EVP-6124 Renal Impairment Study

Renal Impairment

Czech Republic, Hungary
Taiho Oncology, Inc.

Completed

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

Advanced Solid Tumors

United States, Czechia, Serbia
Hoffmann-La Roche

Completed

Effect of Hepatic Impairment on the Pharmacokinetics of Alectinib

Hepatic Impairment

Czechia, Slovakia
Charles University, Czech Republic

Recruiting

PAPSY - Memory in Psychiatry (PAPSY)

Cognitive Impairment

Czechia
Institute for Clinical and Experimental Medicine

Recruiting

rATG Versus rATG Combined With Intravenous Immunoglobulin (IVIG) Induction Immunosuppression in HLA Incompatible Transplantation (INHIBIT) (INHIBIT)

Kidney Transplantation

Czechia
Institute for Clinical and Experimental Medicine

Completed

IgG Antibodies After SARS-CoV-2 mRNA Vaccine in Kidney Transplantation (TASMANIA) (TASMANIA)

Kidney Transplantation

Czechia
Masaryk University
St. Anne's University Hospital Brno, Czech Republic

Completed

The Effect of Transcranial Direct Current Stimulation on Visual Attention in Mild Cognitive Impairment

Mild Cognitive Impairment

Czechia
Masaryk University
Swiss Federal Institute of Technology

Recruiting

Novel, Individualized Brain Stimulation, Network-based Approaches to Improve Cognition (NiBS-iCog)

Healthy Aging | Mild Cognitive Impairment

Czechia
Boehringer Ingelheim

Completed

Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate

Arthroplasty, Replacement | Prevention of Venous Thromboembolism | Moderate Renal Impairment (CrCl 30-50 mL/Min)

Austria, Canada, Czechia, Finland, Netherlands, Sweden
Takeda

Completed

A Study to Evaluate the Effect of Hepatic Impairment on the Single Dose Pharmacokinetics (PK) of Intravenous TAK-954

Healthy Volunteers | Hepatic Impairment

Czechia, Slovakia
Astellas Pharma Inc

Completed

Renal Impairment Study With ASP1941

Type 2 Diabetes Mellitus

Hungary, Poland, Czechia, Slovakia
Hoffmann-La Roche

Completed

An Observational Study of Mircera (Methoxy Polyethylene Glycol-epoetin Beta) in Patients With Chronic Kidney Disease Not On Dialysis

Kidney Disease, Chronic

Czechia
Charles University, Czech Republic

Recruiting

PAMNEU - Memory in Neurology

Cognitive Impairment

Czechia
National Institute of Mental Health, Czech Republic

Completed

Ecologically Valid Virtual Tasks vs Paper-pencil Methods in Cognitive Rehabilitation in Patients With Schizophrenia and Depression

Depression | Schizophrenia | Cognitive Impairment

Czechia
Institute for Clinical and Experimental Medicine

Completed

Molecular Markers of Acute Kidney Injury in Elderly Deceased Donors (MoliDon)

Kidney Transplantation | Acute Kidney Injury

Czechia
Xenothera SAS

Completed

First in Human Study: LIS1, an Induction Treatment in Kidney Transplanted Patients

Kidney Transplant

Czechia
Charles University, Czech Republic
University Hospital Vinohrady; Faculty of Physical Education and Sport

Recruiting

The Effect of Tai Chi and Therapy by Dance and Movement on Blood Irisin Levels in Older Adults Over 65 Years of Age.

Physical Activity | Cognitive Impairment | Aging | Mood Change | Memory Deficits

Czechia
Institute for Clinical and Experimental Medicine

Not yet recruiting

Use of Wearables to Detect Infections in Kidney Transplant Recipients (RENALERT)

Kidney Transplant Infection

Czechia
Novartis Pharmaceuticals

Completed

Evaluation of Renal Function Impairment on the Pharmacokinetics of LEE011

Impaired Renal Function | Normal Renal Function

United States, Germany, Bulgaria, Czechia
Pfizer

Completed

Study of PF-05221304 in Subjects With Varying Degrees of Hepatic Impairment

Hepatic Impairment

United States, Belgium, Czechia, Slovakia
University Hospital Hradec Kralove

Terminated

The Effect of Nimodipine on the Postoperative Cognitive Dysfunction

Mild Cognitive Impairment

Czechia
GlaxoSmithKline

Completed

A Study to Assess the Effects of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Mild, Moderate or Severe Hepatic Impairment.

Asthma

Czechia, Slovakia
University Hospital Hradec Kralove

Completed

The Effect of Blood Pressure on the Postoperative Cognitive Dysfunction

Mild Cognitive Impairment

Czechia
Masaryk University
St. Anne's University Hospital Brno, Czech Republic

Unknown

Modulation of Cognition and Brain Connectivity by Noninvasive Brain Stimulation in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease (LUSTR)

Mild Cognitive Impairment

Czechia
National Cancer Institute (NCI)

Completed

Follow-Up Study of Kidney Cancer Patients

Renal Cancer

Czechia, Poland
Pieris Pharmaceuticals GmbH
FGK Clinical Research GmbH

Completed

Phase 2a Study to Evaluate PRS-080 in Anemic Chronic Kidney Disease Patients

Anemia of Chronic Kidney Disease

Czechia, Germany
Pfizer

Completed

A STUDY TO COMPARE THE PHARMACOKINETICS OF PF-06835919 IN PARTICIPANTS WITH AND WITHOUT HEPATIC IMPAIRMENT

Hepatic Impairment | Healthy Participants

Czechia, Slovakia, Belgium
Daiichi Sankyo, Inc.
PRA Health Sciences

Completed

Pilot PK/PD Study of DS-1093a in Patients With Chronic Kidney Disease

Chronic Renal Disease | Renal Anemia

Czechia, Hungary
Fresenius Kabi
EastHORN Clinical Services in CEE; MLM Medical Labs GmbH; ALS Czech Republic,... and other collaborators

Completed

Short-term Metabolic Effects of Ketosteril® Supplemented Low Protein Diet in Pre-dialysis Chronic Kidney Disease (CKD) Patients (CKD)

Renal Insufficiency, Chronic

Czechia
Institute for Clinical and Experimental Medicine

Active, not recruiting

Immunological Safety and Effectiveness of the First Booster Dose of mRNA Vaccines Against COVID-19 in Kidney Transplant Recipients.

COVID-19 | Kidney Diseases | Vaccine Adverse Reaction | Kidney Transplant; Complications | Rejection Acute Renal | Rejection Chronic Renal

Czechia
University Hospital Ostrava

Completed

Acute Kidney Injury in Severe Trauma

Acute Kidney Injury

Czechia
University Hospital Ostrava

Recruiting

Biomarkers of Kidney Function in Transplant Medicine

Acute Kidney Injury

Czechia
Institute for Clinical and Experimental Medicine

Recruiting

Comprehensive Geriatric Assessment in Kidney Transplantation (CoGeriaTx)

Frailty Syndrome | Kidney Transplant; Complications | Depressive Syndrome

Czechia
University Hospital Ostrava
University Hospital Olomouc; University of Ostrava; Palacky University; Technical...

Completed

Specific miRNAs in Sepsis and Nephrotoxic Antibiotic Treatment

Sepsis | Septic Shock | Acute Kidney Injury

Czechia
Masaryk University
St. Anne's University Hospital Brno, Czech Republic

Not yet recruiting

Noninvasive Temporal Interference Stimulation: Modulating Associative Memory by Targeting Deep-brain Targets (Deep-HiPs)

Alzheimer Disease | Healthy Aging | Mild Cognitive Impairment | Memory Disorders in Old Age

Czechia
B.Braun Avitum AG
Winicker Norimed GmbH

Completed

Determination In-vivo KUF for Diacap Pro Hemodialyser

Renal Insufficiency,Chronic | Kidney Insufficiency | Kidney Disease, End-Stage | Kidney Failure,Chronic

Czech Republic
Oncopeptides AB

Terminated

PK of Melphalan During Treatment With Melflufen and Dexamethasone in Patients With RRMM and Impaired Renal Function (BRIDGE)

Multiple Myeloma | Renal Impairment

Greece, Czechia, Poland
Vascular surgery, University hospital Královské...
Belfast Health and Social Care Trust

Active, not recruiting

Validation of Arterio Venous Access Stage (AVAS) Classification (VAVASC)

Arteriovenous Fistula | Kidney Failure | Arteriovenous Graft | Dialysis Access Malfunction | Dialysis Related Complication

Czechia
Value Outcomes Ltd.

Recruiting

Description of Treatment Patterns and Population Characteristics of Pre-dialysis CKD Patients in the Czech Republic

Chronic Kidney Diseases

Czechia
Vertex Pharmaceuticals Incorporated

Completed

Study of Lumacaftor in Combination With Ivacaftor in Subjects With Moderate Hepatic Impairment and Healthy Subjects

Healthy | Hepatic Impairment

Slovakia, Czech Republic
AstraZeneca
PRA Health Sciences

Completed

Pharmacokinetics, Safety & Tolerability of ZD4054 (Zibotentan) in Subjects With Normal, Mild, Moderate and Severe Hepatic Impairment

Hepatic Impairment

Czech Republic

Clinical Trials on Kidney Impairment in Czechia

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