Clinical Trials on Kidney Impairment

Total 15472 results

Incyte Corporation

Completed

Study to Evaluate the Pharmacokinetics, Safety, and Pharmacodynamics of INCB000928 in Participants With Impaired Renal Function and Hemodialysis

Hemodialysis | Renal Impairment

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

A Post-Marketing Clinical Pharmacokinetics Study Of Gabapentin In Japanese Epileptic Subjects With Renal Impairment

Renal Impairment

Japan
Bausch Health Americas, Inc.

Completed

Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function

Renal Impairment

United States
Mitsubishi Tanabe Pharma America Inc.

Completed

PK Study in Subjects With Renal Impairment (Severe and if Required Mild & Moderate) Compared to Subjects With Normal Renal Function

Renal Impairment | Normal Renal Function

Germany
University of Regensburg
Novartis Pharmaceuticals

Unknown

CNI-free "Bottom"-up Immunosuppression in Patients Undergoing Liver Transplantation (BUILT_01)

Liver Transplantation | Renal Impairment | Everolimus

Germany
Guangdong Raynovent Biotech Co., Ltd

Completed

Pharmacokinetics of Leritrelvir(RAY1216) in Participants With Severe Kidney Disease

Kidney Impairment

China
Guangdong Raynovent Biotech Co., Ltd

Recruiting

Pharmacokinetics of ZSP1273 in Participants With Severe Kidney Disease

Kidney Impairment

China
Bracco Diagnostics, Inc

Terminated

Renal Safety of Iopamidol Versus Iodixanol During Coronary Angiography in Diabetic Patients (RECARE)

Diabetes Mellitus | Chronic Renal Impairment

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetics of LCQ908 in Patients With Renal Impairment

Renal Impairment

United States
Exelixis

Completed

A Single-Dose Study to Assess the Pharmacokinetics of Cabozantinib (XL184) Capsules in Subjects With Impaired Renal Function

Healthy | Renal Impairment

United States
Boryung Pharmaceutical Co., Ltd
Seoul National University Hospital

Completed

A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Renal Impairment Patients and Healthy Volunteers

Renal Impairment

Korea, Republic of
Taiho Oncology, Inc.

Completed

A Phase I Study of TAS-102 in Patients With Advanced Solid Tumors With Renal Impairment

Advanced Solid Tumors

United States, Czechia, Serbia
Sahlgrenska University Hospital, Sweden

Completed

Renal Perfusion, Filtration and Oxygenation During Cardiopulmonary Bypass (CPB) (ECCSTUD)

Renal Impairment | Complication of Extracorporeal Circulation

Sweden
AstraZeneca

Completed

To Compare the Pharmacokinetics of a Single Oral Dose of TC-5214 in Subjects With Renal Impairment and With Subjects With Normal Renal Function

Renal Impairment | Healthy Volunteers | Pharmacokinetics | Patients

United States
Hamamatsu University

Suspended

Effective Adjunctive Use of Pergolide for Cognitive Impairment and Negative Symptoms in Schizophrenia

Schizophrenia | Negative Symptoms | Cognitive Impairments

Japan
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Completed

A Study in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function

Healthy Subjects | Subjects With Renal Impairment

China
Shanghai Mental Health Center

Recruiting

Influence Factors and Cognitive Characteristics in Unipolar and Bipolar Depression:Based on the THINC-it Tool

Cognitive Impairments

China
Boehringer Ingelheim

Completed

Efficacy and Safety of Telmisartan in Hypertensive Patients With Mild/Moderate or Severe Renal Impairment or Requiring Hemodialysis (ESPRIT)

Hypertension
Larry J. Siever
New York State Psychiatric Institute

Unknown

Clinical Testing of a D1 Agonist for Cognitive Enhancement in Schizotypal Personality Disorder (SPD)

Schizotypal Personality Disorder | Cognitive Impairments

United States
Novartis Pharmaceuticals

Completed

Multiple Dose Pharmacokinetics of LCZ696 and Its Metabolites in Subjects With Severe Renal Impairment vs. Matched Healthy Subjects With Normal Renal Function

Pharmacokinetics | Healthy Volunteer | Renal Impaired

Russian Federation, Germany, Serbia
National Hepatology & Tropical Medicine Research...

Completed

Norepinephrine Infusion Versus Midodrine & Octreotide in Patients With Hepatorenal Syndrome Type 1.

Renal Impairment in Hepatorenal Syndrome

Egypt
Bayer

Terminated

Study on the Safety of Neladenoson Bialanate, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Dug Given as a Single Oral Dose of 10 mg Immediate Release Tablet in Participants With Renal Impairment and Healthy Participants Matched for Age-, Gender-, and Weight

Pharmacology, Clinical

Germany
Shaare Zedek Medical Center

Completed

Renal Impairment Associated With Colistin Levels

Sepsis

Israel
Bayer

Completed

Study on the Safety of BAY 63-2521, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug Given as a Single Oral Dose of 1 mg Tablet in Participants With Renal Impairment and Healthy Participants Matched for Age-, Gender-, and Weight

Clinical Pharmacology

Germany
AstraZeneca

Completed

Renal Impairment Study

Reflux | Renal Excretion

Sweden
Ascelia Pharma AB

Completed

Safety and Diagnostic Efficacy of Mangoral in Participants With Focal Liver Lesions and Reduced Kidney Function (SPARKLE)

Severe Renal Impairment | Known or Suspected Focal Liver Lesions

United States, Italy, Germany, Poland, Russian Federation, Sweden, Turkey, Argentina, Colombia, Mexico
Maastricht University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Envida...

Terminated

Neurotoxic Adverse Effects of Morphine and Oxycodone for Pain in Terminal Patients With Diminished Renal Function (MOSART)

Pain | Renal Impairment | Terminal Illness

Netherlands
Mast Therapeutics, Inc.

Completed

Study of the Effect of Renal Impairment on the Pharmacokinetics of Vepoloxamer

Healthy Volunteers | Renal Impaired | Pharmacokinetics of Vepoloxamer

United States
Astellas Pharma Global Development, Inc.
Basilea Pharmaceutica International Ltd

Completed

Study of the Effect of Renal Impairment on the Pharmacokinetics of Isavuconazole.

Healthy Volunteers | Pharmacokinetics of Isavuconazole | Renal Impaired

United States
University of Pennsylvania

Withdrawn

LDX for the Treatment of Cognitive Functioning Issues in Women Post-Oophorectomy (LDX)

Cognitive Impairments | RRSO

United States
Entasis Therapeutics

Completed

Evaluation of the Pharmacokinetics, Safety, and Tolerability of Intravenous ETX2514 and Sulbactam Administered Concurrently to Subjects With Various Degrees of Renal Impairment and Healthy Matched Control Subjects

Acinetobacter Baumannii Infection

United States
Bayer

Completed

Renal Impairment Study

Clinical Trial, Phase I

Germany
Astellas Pharma Inc

Completed

ASP1517 Pharmacokinetics Study in Anemia Patients on Hemodialysis

Anemia | Hemodialysis | Renal Impairment

Japan
Northwestern University
National Cancer Institute (NCI)

Completed

The "Light for the Brain" Study

Depression | Quality of Life | Fatigue | Sleep | Hematopoietic Stem Cell Transplantation | Cognitive Impairments

United States
Bournemouth University
Dorset HealthCare University NHS Foundation Trust

Completed

The Effect of Vegetable Oil on Cognitive Functions of MCI Patients (DICe)

Metabolic Ketosis | Cognitive Impairments, Mild

United Kingdom
Assistance Publique Hopitaux De Marseille

Unknown

Blood-Brain Barrier Evaluation In Nephrology (BREIN) (BREIN)

End Stage Renal Disease and Cognitive Impairment

France
Daiichi Sankyo, Inc.

Completed

A Phase 2 Exploratory Study of CS-3150 in Japanese Hypertensive Patients With Moderate Renal Impairment

Hypertension

Japan
Novartis Pharmaceuticals

Completed

PK of Serelaxin in Severe Renal Impairment and ESRD (CRLX030A2102)

End-Stage Renal Disease | Renal Failure, Chronic

Germany
Boehringer Ingelheim

Completed

Treatment of Patients Undergoing Primary Unilateral Elective Total Knee or Hip Replacement With Dabigatran Etexilate

Arthroplasty, Replacement | Prevention of Venous Thromboembolism | Moderate Renal Impairment (CrCl 30-50 mL/Min)

Austria, Canada, Czechia, Finland, Netherlands, Sweden
GlaxoSmithKline

Completed

Observational Pharmacokinetic Study Of GW679769 In Subjects With Renal Impairment

Vomiting

United States
Mylan Inc.
Theravance Biopharma

Completed

Pharmacokinetics of TD-4208 in Patients With Severe Renal Impairment

Renal Impairment

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Terminated

An Open Label Pharmacokinetic Study Of Gabapentin In Japanese Subjects With Renal Impairment Including Hemodialysis

PK Properties Of Gabapentin In Subjects With Impaired Renal Function

Japan
Natalie Garratt

Completed

The Kidney and The Brain Study - Assessment of Cognitive Impairment in Advanced CKD

Chronic Kidney Diseases | Cognitive Impairment | Dementia | End Stage Renal Disease | Hemodialysis Complication | Renal Transplant | Peritoneal Dialysis Complication

United Kingdom
Novartis Pharmaceuticals

Completed

Pharmacokinetics of Vildagliptin in Mild, Moderate and Severe Renal Impaired Patients

Diabetes | Renal Impairment

Russian Federation
Merck Sharp & Dohme LLC

Terminated

A Study of MK-7145 in Participants With Renal Insufficiency (Part I) and Heart Failure With Renal Insufficiency (Part II) (MK-7145-011)

Heart Failure | Renal Impairment
The University of Hong Kong
Haven of Hope Hospital; The Social Innovation and Entrepreneurship Development...

Completed

Tablet-based Interactive Games in Elderly With Cognitive Impairment and Persons With Intellectual Disability

Intellectual Disability | Technology | Cognitive Impairments

Hong Kong
Barts & The London NHS Trust

Unknown

Development of a Biomarker Panel for the Earlier Prediction of Acute Kidney Injury in Patients With Diabetes (BIOMARKERS)

Diabetes Mellitus | Renal Impairment

United Kingdom
Bayer

Recruiting

A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Chronic Kidney Disease | Hepatic Impairment

United States
Sankyo Pharma Gmbh

Completed

Olmesartan Medoxomil in Hypertension and Renal Impairment

Renal Impairment | Essential Hypertension

Germany
Hospital de Clinicas de Porto Alegre

Unknown

Low-dose Albumin Solution in SBP: a Randomized Double-blind Pilot Study (ALTERNATE)

Renal Impairment | All Cause Mortality

Brazil

Clinical Trials on Kidney Impairment

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Serbia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations