Clinical Trials on Laceration of Skin

Total 73329 results

Inhibrx, Inc.

Recruiting

Phase 1 Study of INBRX-109 in Subjects With Locally Advanced or Metastatic Solid Tumors Including Sarcomas

Sarcoma | Pancreatic Adenocarcinoma | Ewing Sarcoma | Gastric Adenocarcinoma | Chondrosarcoma | Solid Tumors | Malignant Pleural Mesothelioma | Colorectal Adenocarcinoma | GIST | SDH-deficient Solid Tumors

United States
National Eye Institute (NEI)

Recruiting

National Eye Institute Biorepository for Retinal Diseases

Age-Related Macular Degeneration | Diabetic Retinopathy | Retinal Vein Occlusion | Retinal Disease | Von Hippel-Lindau Syndrome

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Terminated

A Clinical Trial to Evaluate the Safety and Efficacy of AL2846 Capsules in Chinese Patients With Type I Neurofibromatosis

Neurofibromatosis and Malignant Peripheral Nerve Sheath Tumors

China
Hoffmann-La Roche

Active, not recruiting

A Dose Escalation and Expansion Study of Lomvastomig, a PD-1/TIM-3 Bispecific Antibody, in Participants With Advanced and/or Metastatic Solid Tumors

Metastatic Melanoma | Non-small Cell Lung Cancer (NSCLC) | Solid Tumors | Esophageal Squamous Cell Carcinoma (ESCC) | Small Cell Lung Cancer (SCLC)

United States, Korea, Republic of, Denmark, France, Spain, New Zealand
National Cancer Institute (NCI)

Completed

flt3L With or Without Vaccine Therapy in Treating Patients With Metastatic Melanoma or Renal Cell Cancer

Recurrent Melanoma | Stage IV Melanoma | Stage IV Renal Cell Cancer | Recurrent Renal Cell Cancer

United States
M.D. Anderson Cancer Center
Bristol-Myers Squibb

Completed

Dasatinib as Therapy for Myeloproliferative Disorders (MPDs)

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Polycythemia Vera | Myelofibrosis | Leukemia, Myelomonocytic, Chronic | Hypereosinophilic Syndrome | Mastocytosis | Agnogenic Myeloid Metaplasia

United States
Forma Therapeutics, Inc.

Completed

A Study of FT-2102 in Patients With Advanced Solid Tumors and Gliomas With an IDH1 Mutation

Cohort 1a and 1b: Glioma (Advanced Gliomas and Glioblastoma Multiforme) | Cohort 2a and 2b: Hepatobiliary Tumors (Hepatocellular Carcinoma, Bile Duct Carcinoma, Intrahepatic Cholangiocarcinoma, Other Hepatobiliary Carcinomas) | Cohort 3a and 3b: Chondrosarcoma | Cohort 4a and 4b: Intrahepatic... and other conditions

United States, Korea, Republic of, Australia, United Kingdom, Spain, France
Massachusetts General Hospital

Suspended

A Randomized Trial Measuring the Effect of Decision Aids on Patients' Satisfaction, Conflict of Decision-making and Clinical Outcome

Carpal Tunnel Syndrome | Trapeziometacarpal Arthrosis | Trigger Finger | Distal Radius Fractures | Cubital Tunnel Syndrome

United States
Qlaris Bio, Inc.

Completed

A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101

Ocular Hypertension | Glaucoma | Glaucoma Congenital | Sturge-Weber Syndrome (SWS)

United States
Technische Universität Dresden
Tumorzentrum Regensburg, Institut für Qualitätssicherung und Versorgungsforschung... and other collaborators

Completed

Effectiveness of Care in Certified Cancer Centres in Germany (WiZen)

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Prostate Cancer | Cervix Cancer | Endometrial Cancer | Bronchial Cancer | Head and Neck Tumor | CNS Tumor

Germany
Stony Brook University

Active, not recruiting

A Pilot Biomarker Study Assessing Alpha-synuclein Aggregates Across Biofluid Reservoirs in Patients With Synucleinopathies

Parkinson Disease | Multiple System Atrophy | Normal Pressure Hydrocephalus | Rapid Eye Movement Sleep Behavior Disorder

United States
Washington University School of Medicine
Massachusetts General Hospital; Mayo Clinic; McGill University; University of California... and other collaborators

Enrolling by invitation

North American Prodromal Synucleinopathy Consortium (NAPS)

Parkinson Disease | Lewy Body Disease | Multiple System Atrophy | REM Sleep Behavior Disorder | Dementia With Lewy Bodies | REM Sleep Parasomnias

United States, Canada
Incyte Corporation

Completed

Pembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid Tumors

Melanoma | Breast Cancer | Head and Neck Cancer | Pancreatic Cancer | Lung Cancer | Endometrial Cancer | Solid Tumors | Renal Cell Carcinoma (RCC) | Colorectal Cancer (CRC) | UC (Urothelial Cancer) | MMR-deficient Tumors

United States
Skane University Hospital
AC Immune SA

Completed

Optimization of Morphomer-based Alpha-synuclein PET Tracers

Parkinson Disease | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Dementia With Lewy Bodies

Sweden
University Health Network, Toronto

Enrolling by invitation

Decreased Empathy and Emotion Recognition in Patients With Neurodegenerative Disease (Empathy)

Parkinson Disease | Dementia | Alzheimer Disease | Vascular Dementia | Frontotemporal Lobar Degeneration | Neuro-Degenerative Disease | Caregiver Burnout

Canada
University Health Network, Toronto

Completed

Study of Azacitidine and Durvalumab in Advanced Solid Tumors (METADUR)

Microsatellite Stable Colorectal Carcinoma | Platinum Resistant Epithelial Ovarian Cancer Type II | Estrogen Receptor Positive and HER2 Negative Breast Cancer

Canada
Boston Children's Hospital

Completed

Offset Analgesia as a Measure of Central Sensitization in Children

CRPS (Complex Regional Pain Syndromes) | Chronic Pain Syndrome | Musculoskeletal Pain Disorder | Chronic Daily Headache | Functional Abdominal Pain Syndrome

United States
Masonic Cancer Center, University of Minnesota
National Marrow Donor Program

Completed

Stem Cell Transplant for Hemoglobinopathy

Sickle Cell Disease | Thalassemia | Severe Congenital Neutropenia | Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome

United States
Oregon Health and Science University

Terminated

Dietary Cholesterol and Defects in Cholesterol Synthesis in Mevalonate Kinase Deficiency

Immune System Diseases | Lipid Metabolism, Inborn Errors | Mevalonic Aciduria | Mevalonate Kinase Deficiency | Periodic Fever Syndromes, Hereditary

United States
Cristiana Sessa

Completed

Dose Finding Study Of PF-05212384 With Paclitaxel And Carboplatin In Patients With Advanced Solid Tumor (IOSI-NDU-001)

Breast Cancer | NSCLC | Endometrial Cancer | Ovary Cancer | Small Cell Lung Cancer (SCLC) | Head and Neck (HNSCC)

Switzerland
University of Minnesota
GE Healthcare

Completed

Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism

Parkinson Disease | Gaucher Disease | Idiopathic Rapid Eye Movement Sleep Disorder

United States
University of Pennsylvania
National Institute on Aging (NIA)

Completed

Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Lewy Body Disease | Dementia, Vascular | Delirium, Dementia, Amnestic, Cognitive Disorders

United States
University of Texas Southwestern Medical Center

Withdrawn

Effects of Growth Hormone in Chronically Ill Children

HIV Infections | Cerebral Palsy | Crohn Disease | Hurler Syndrome | Juvenile Rheumatoid Arthritis

United States
Masonic Cancer Center, University of Minnesota

Completed

Stem Cell Transplant for Bone Marrow Failure Syndromes

Diamond-Blackfan Anemia | Shwachman-Diamond Syndrome | Kostmann's Neutropenia

United States
Eisai Inc.

Completed

A Study of ZYC300 Administered With Cyclophosphamide Pre-Dosing

Breast Cancer | Ovarian Cancer | Prostate Cancer | Colon Cancer | Renal Cancer

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Safely Stopping Pre-medications in Patients With Breast Cancer Who Are Receiving Paclitaxel

Anatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage III Breast Cancer AJCC v8 | Anatomic... and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

Diffuse Large B-Cell Lymphoma | Chronic Lymphocytic Leukemia | Anaplastic Large Cell Lymphoma | Small Lymphocytic Lymphoma | Angioimmunoblastic T-Cell Lymphoma | Hepatosplenic T-Cell Lymphoma | Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Aggressive Non-Hodgkin Lymphoma | Enteropathy-Associated... and other conditions

United States
OHSU Knight Cancer Institute
Genentech, Inc.; Oregon Health and Science University

Withdrawn

SMMART Adaptive Clinical Treatment (ACT) Trial

Anatomic Stage III Breast Cancer AJCC v8 | Recurrent Ovarian Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Recurrent... and other conditions

United States
Universidad de Granada
Spanish Society of Community Pharmacy; Pharmaceutical Association, Valencia... and other collaborators

Completed

Implementation of a Minor Ailment Service in Community Pharmacy Practice (INDICA+PRO)

Hyperhidrosis | Burns | Musculoskeletal Pain | Vomiting | Sleep Disorder | Constipation | Diarrhea | Cough | Dermatitis | Soft Tissue Injuries | Dry Eye | Headache | Varicose Veins | Dysmenorrhea | Flatulence | Heartburn | Nasal Congestion | Hemorrhoids | Dental Trauma | Acne | Vaginal Candidiasis | Sore Throat | Cold | Rash | Red Eye | Stress Disorder... and other conditions

Spain
University College Cork

Not yet recruiting

Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography (DiFuSE)

Gestational Diabetes | Neonatal Encephalopathy | Diastolic Dysfunction | Trisomy 21 | Transient Tachypnea of the Newborn | Small for Gestational Age at Delivery

Ireland
IRCCS San Raffaele

Recruiting

Study on the Quality of Life and Pathological State in Patients Who Underwent Radical Cystectomy

Bladder Cancer | Muscle-Invasive Bladder Carcinoma | Radical Cystectomy | Urinary Diversion | Bladder Urothelial Carcinoma | Progression, Disease | Bladder Cancer Stage II | Bladder Cancer Stage IV | Muscle Invasive Bladder Urothelial Carcinoma | Neobladder | Bladder Cancer TNM Staging | Bladder Cancer Stage... and other conditions

Italy
University Hospital Padova

Recruiting

Water and Electrolytes Content in HYpertension (WHYSKI) in the SKIn (WHYSKI)

Hypertension | Essential Hypertension | Hyperaldosteronism | Aldosteronism | Conn Adenoma | Aldosterone Disorder | Aldosterone-producing Adenoma | Bilateral Adrenal Hyperplasia

Italy
Cyclo Therapeutics, Inc.

Recruiting

Phase 3 Study to Evaluate Intravenous Trappsol(R) Cyclo(TM) in Pediatric and Adult Patients With Niemann-Pick Disease Type C1 (TransportNPC)

Niemann-Pick Disease, Type C1

United States, Spain, Israel, Taiwan, Brazil, Germany, Australia, Poland, Turkey, Italy, United Kingdom
Fred Hutchinson Cancer Center
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Cord Blood Transplant With Dilanubicel for the Treatment of HIV Positive Hematologic Cancers

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm | Acute Myeloid Leukemia | Acute Lymphoblastic Leukemia | Acute Erythroid Leukemia | Acute Megakaryoblastic Leukemia | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Myelodysplastic Syndrome With Excess Blasts | Chronic Myelogenous Leukemia, BCR-ABL1... and other conditions

United States
Inhibrx, Inc.

Recruiting

Study of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck Cancer (PDL1x41BB)

Melanoma | Renal Cell Carcinoma | Nasopharyngeal Carcinoma | Gastric Adenocarcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Adenocarcinoma | Metastatic Solid Tumors | Oropharyngeal Carcinoma

United States
Masonic Cancer Center, University of Minnesota

Recruiting

Hematopoietic Stem Cell Transplantation in the Treatment of Infant Leukemia

Myelodysplastic Syndromes | Leukemia | Previously Treated Myelodysplastic Syndrome | Secondary Acute Myeloid Leukemia | Childhood Acute Myeloid Leukemia in Remission | Childhood Acute Lymphoblastic Leukemia in Remission | Recurrent Childhood Acute Myeloid Leukemia | Secondary Myelodysplastic Syndrome and other conditions

United States
Inovio Pharmaceuticals

Completed

VGX-3100 Delivered Intramuscularly (IM) Followed by Electroporation (EP) for the Treatment of HPV-16 and/or HPV-18 Related Anal or Anal/Peri-Anal, High Grade Squamous Intraepithelial Lesion (HSIL) in Individuals Seronegative for Human Immunodeficiency Virus (HIV)-1/2

Anal Neoplasm

United States, Canada
Genocea Biosciences, Inc.

Terminated

TiTAN-1: Safety, Proliferation and Persistence of GEN-011 Autologous Cell Therapy

Melanoma | Renal Cell Carcinoma | Squamous Cell Carcinoma of Head and Neck | Non-small Cell Lung Cancer | Small-cell Lung Cancer | Urothelial Carcinoma | Anal Squamous Cell Carcinoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Durvalumab Before Surgery in Treating Patients With Oral Cavity or Oropharynx Cancer

Human Papillomavirus Infection | Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage IVA Oropharyngeal Squamous Cell Carcinoma | Stage IVB Oropharyngeal Squamous Cell Carcinoma | Stage IVC Oropharyngeal Squamous Cell Carcinoma | Stage I Oropharyngeal Squamous Cell Carcinoma | Stage II Oropharyngeal... and other conditions

United States
Jerry Vockley, MD, PhD
Ultragenyx Pharmaceutical Inc

No longer available

Compassionate Use of Triheptanoin (C7) for Inherited Disorders of Energy Metabolism

Barth Syndrome | Mitochondrial Trifunctional Protein Deficiency | Very Long-chain acylCoA Dehydrogenase (VLCAD) Deficiency | Carnitine Palmitoyltransferase Deficiencies (CPT1, CPT2) | Long-chain Hydroxyacyl-CoA Dehydrogenase Deficiency | Glycogen Storage Disorders | Pyruvate Carboxylase Deficiency... and other conditions

United States
Marcelo Bonomi

Recruiting

Cemiplimab, Low-Dose Paclitaxel and Carboplatin for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC... and other conditions

United States
Centre Hospitalier Universitaire de Liege
Sanofi; Takeda; University of Liege; Orchard Therapeutics; Centre Hospitalier Régional... and other collaborators

Recruiting

Baby Detect : Genomic Newborn Screening

Congenital Adrenal Hyperplasia | Hemophilia A | Hemophilia B | Mucopolysaccharidosis I | Mucopolysaccharidosis II | Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Sickle Cell Disease | Fanconi Anemia | Chronic Granulomatous Disease | Wilson Disease | Severe Congenital Neutropenia | Ornithine Transcarbamylase... and other conditions

Belgium
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Massachusetts General Hospital
Trefler Foundation

Recruiting

Adapting the Tumor Board Model for Mental Illness and Cancer

Cancer | Breast Cancer | Head and Neck Cancer | Schizophrenia | Lung Cancer | Bipolar Disorder | Gastrointestinal Cancer | Genitourinary Cancer | Severe Major Depression

United States
Washington University School of Medicine
Massachusetts General Hospital; Mayo Clinic; McGill University; University of California... and other collaborators

Recruiting

North American Prodromal Synucleinopathy Consortium Stage 2 (NAPS2)

Parkinson Disease | Multiple System Atrophy | REM Sleep Behavior Disorder | Dementia With Lewy Bodies | REM Sleep Parasomnias | Lewy Body Dementia

United States, Canada
Leiden University Medical Center

Recruiting

89Zr-Bevacizumab PET/CT Imaging in NF2 Patients

Neurofibromatosis 2

Netherlands
First Affiliated Hospital of Fujian Medical University

Recruiting

Treatment of Transcranial Alternating Current Stimulation（tACS）on Cerebellar Ataxia

Spinocerebellar Ataxia Type 3 | Multiple System Atrophy-cerebellar Type

China
Bolt Biotherapeutics, Inc.
Bristol-Myers Squibb

Recruiting

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

HER2-positive Breast Cancer | HER2-positive Colorectal Cancer | HER2-positive Solid Tumors | HER2-positive Gastroesophageal Cancer | HER2-positive Endometrial Cancer

United States, Spain, France, Korea, Republic of, Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Melanoma | Cervical Cancer | Breast Cancer | Diarrhea | Ovarian Cancer | Lung Cancer | Colitis | Uterine Cancer | Malignant Genitourinary System Neoplasm

United States
University of Aarhus

Recruiting

Comparison of Gastrointestinal Motility in Healthy Children and Children With Constipation

Constipation | Childhood Acute Lymphoblastic Leukemia | Neurofibromatosis 1 | Chronic Constipation With Overflow

Denmark

Clinical Trials on Laceration of Skin

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Medical Conditions

Drug Interventions

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CROs in Colombia

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Rare Diseases

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