Clinical Trials on Leptomeningeal Disease (LMD)

Total 381532 results

Alcon Research

Terminated

Anecortave Acetate Risk-Reduction Trial (AART)

AMD

United States
Wake Forest University Health Sciences
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Recruiting

Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis

Metastatic Breast Cancer | Leptomeningeal Disease

United States
Sichuan University

Recruiting

Safety and Efficacy of Whole Brain LDRT+ICI+Intrathecal Chemotherapy in Refractory Meningeal Metastasis of Lung Cancer

NSCLC | PD-1 Inhibitor | Leptomeningeal Metastasis | Low Dose Radiotherapy

China
Y-mAbs Therapeutics

Terminated

131I-omburtamab Radioimmunotherapy for Neuroblastoma Central Nervous System/Leptomeningeal Metastases

Neuroblastoma | Leptomeningeal Metastases | CNS Metastases

United States, Denmark, Japan, Spain
Alcon Research

Terminated

Anecortave Acetate Risk-Reduction Trial (AART)

Dry AMD

United States
Yeditepe University Hospital

Completed

A Method to Determine the Size of Laryngeal Mask Airway (LMA)

Ear Based ProSeal LMA

Turkey
Johnson & Johnson Vision Care, Inc.

Completed

Impact of Soft Contact Lenses on Lid-Parallel Conjunctival Folds

Lid-Parallel Conjunctival Folds

Germany
Angiochem Inc

Not yet recruiting

ANG1005 in Leptomeningeal Disease From Breast Cancer (ANGLeD)

Brain Metastases | Leptomeningeal Metastases | HER2-negative Breast Cancer | Leptomeningeal Carcinomatosis
Ajou University School of Medicine

Completed

Videoscope Guided Flexible LMA Insertion

Ideal Position of LMA Flexible

Korea, Republic of
University Hospital, Bordeaux
Laboratoires Thea

Completed

Lutein Influence on Macula of Persons Issued From Amd Parents (LIMPIA)

Persons Issued From Amd Parents

France
Alcon Research

Completed

A Phase II Study of Anecortave Acetate for the Treatment of Exudative Age-Related Macular Degeneration

AMD
Alcon Research

Terminated

Lid Wiper Epitheliopathy Trial

Lid Wiper Epitheliopathy
Carl Zeiss Meditec, Inc.
DataMed Devices Inc.

Completed

Repeatability and Reproducibility of Cirrus HD-OCT Macular Retinal Pigment Epithelium Elevation

Dry AMD With Macular Drusen

United States
National Eye Institute (NEI)

Completed

Age-Related Eye Disease Study 2 (AREDS2) 10-year Follow-On

Cancer | Cataract | AMD

United States
Tel-Aviv Sourasky Medical Center

Unknown

Gait Disturbances and Hips Bone Mineral Density

Difference in BMD Between Both Hips
AstraZeneca

Completed

Physician and Patient Perception of Adjustable Maintenance Dosing of Symbicort Turbuhaler (REALITY)

Perception of Physicians & Patients of AMD
University of Aarhus

Recruiting

Proton Cranio-spinal Irradiation for Leptomeningeal Metastasis (CSI ProLong)

Leptomeningeal Metastasis

Denmark
Dartmouth-Hitchcock Medical Center

Completed

Circulating Tumor DNA in Cerebrospinal Fluid as an Early Biomarker of Leptomeningeal Metastasis (LM)

Leptomeningeal Metastasis

United States
Cancer Institute and Hospital, Chinese Academy...

Completed

Tomotherapy for Leptomeningeal Metastases

Leptomeningeal Metastasis

China
Guangzhou Medical University

Not yet recruiting

Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors

Leptomeningeal Metastasis

China
Plus Therapeutics

Recruiting

Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases (ReSPECT-LM)

Leptomeningeal Metastasis

United States
The First Hospital of Jilin University

Completed

Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors

Leptomeningeal Metastasis

China
Oraya Therapeutics, Inc.

Completed

INTREPID - IRay Plus Anti-VEGF Treatment For Patients With Wet AMD (INTREPID)

Eye Diseases | Age-Related Macular Degeneration | Macular Degeneration | Retinal Diseases | AMD | Wet AMD | Wet Age-Related Macular Degeneration

United Kingdom, Czech Republic, Austria, Germany, Italy
The First Hospital of Jilin University
The Second Hospital of Hebei Medical University; Second Affiliated Hospital... and other collaborators

Recruiting

Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis

Leptomeningeal Metastasis

China
The First Hospital of Jilin University

Completed

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

Leptomeningeal Metastasis

China
University of Toronto
Mount Sinai Hospital, Canada

Unknown

What Are the Effects of Music on Temporomandibular Disorder Symptoms? (TMD)

TMD

Canada
Universidad Complutense de Madrid

Unknown

Psycho-social Aspects After a Physiotherapy Intervention in Chronic TMD Pain

TMD
Meir Medical Center

Unknown

Expression and Localization of FP Prostaglandin Receptor in Human Ocular Tissues

Malposition of the Lower Lid
Samsung Medical Center

Completed

Optimal Head Rotation and External Landmark for Internal Jugular Vein Cannulation After Placement of Proseal Laryngeal Mask Airway

General Anesthesia With Laryngeal Mask Airway (LMA)

Korea, Republic of
Kadmon Corporation, LLC

Completed

Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal Metastases

Non-Small Cell Lung Cancer | Brain Metastases | Leptomeningeal Metastases

United States
DreamFace Technologies, LLC
National Institute on Aging (NIA)

Completed

Testing the Efficacy of Social Robot-led Yoga

Testing the Efficacy of Social Robot-led Yoga

United States
Tanta University

Recruiting

Blockbuster LMA Versus Baska Mask in Laparoscopic Cholecystectomy

Laparoscopic Cholecystectomy | Baska Mask | Blockbuster LMA

Egypt
Y-mAbs Therapeutics

Withdrawn

177Lu-DTPA-Omburtamab Radioimmunotherapy for Leptomeningeal Metastasis From Solid Tumors (Breast, NSCLC, Malignant Melanoma)

Solid Tumor, Adult | Leptomeningeal Metastasis

United States, United Kingdom
Wenzhou Medical University

Not yet recruiting

Quantitative Assessment of Lid Margin Vascularity Using SS-OCTA

Ss-octa | Lid Margin Blood Flow Density | MGD
RWTH Aachen University

Completed

Emergence Times and Airway Reactions in General Laryngeal Mask Airway Anesthesia

Anesthesia With Use of LMA (Laryngeal Mask Airway)

Germany
Samsung Medical Center

Active, not recruiting

Study of AZD9291 in NSCLC Patients Harboring T790M Mutation Who Failed EGFR TKI and With Brain and/or LMS

Non-Small Cell Lung Cancer With EGFR T790M Mutation | With Brain and/or Leptomeningeal Metastasis | Failed Tyrosine Kinase Inhibitors

Korea, Republic of
Al-Azhar University

Completed

Computer Guided Versus Conventional TMJ Injection

TMD

Egypt
Oraya Therapeutics, Inc.

Withdrawn

Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV)

Macular Degeneration | Age-related Macular Degeneration | AMD | Wet AMD | Wet Age-related Macular Degeneration

United Kingdom, Italy
Doheny Image Reading Center

Withdrawn

Image Biomarkers for Progression of AMD (IBPAMD)

AMD
University of Maryland, Baltimore
Neuroscience Research Australia

Completed

Validation of a Novel Cortical Biomarker Signature for Pain (PREDICT)

TMD

United States, Australia
Taipei Veterans General Hospital, Taiwan
National Yang Ming University

Completed

Study Effect of Red Wine Consumption on Endothelial Progenitor Cells and Endothelial Function

Endothelial Progenitor Cells Numbers | Endothelial Function (FMD)

Taiwan
Centre Hospitalier Universitaire Dijon

Completed

Study the Signs of Ocular Degeneration in a Population Cohort (Dijon 3C Montrachet Cohort) (3C)

Glaucoma | AMD

France
Massachusetts General Hospital
Merck Sharp & Dohme LLC

Terminated

Pembrolizumab And Lenvatinib In Leptomeningeal Metastases

Solid Tumor | Solid Tumor, Adult | Leptomeningeal Metastasis

United States
Reata, a wholly owned subsidiary of Biogen

Terminated

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis (LMD)

Leptomeningeal Carcinomatosis

United States
Lawson Health Research Institute

Completed

Low Vision Study Comparing EV Training vs. CCTV for AMD Rehabilitation (AMD)

AMD

Canada
AbbVie

Recruiting

Pivotal 1 Study of RGX-314 Gene Therapy in Participants With nAMD (ATMOSPHERE)

CNV | AMD | nAMD | Wet AMD | Wet Age-related Macular Degeneration | wAMD

United States
Guangzhou Medical University

Recruiting

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Leptomeningeal Metastasis

China
Tyrogenex
International Drug Development Institute; SynteractHCR

Terminated

X-82 to Treat Age-related Macular Degeneration

Eye Diseases | Macular Degeneration | Retinal Degeneration | Retinal Diseases | Age-Related Macular Degeneration (AMD) | Exudative Age-related Macular Degeneration | AMD | Macular Degeneration, Age-related, 10

United States
Yuzuncu Yıl University

Completed

Ozonated Olive Oil and Low-Level Laser Therapy in TMD Treatment

TMD

Turkey
Notal Vision Ltd.

Completed

Usability and Ergonomic Evaluation of Self-Positioning System for Retinal Imaging

AMD Population - Intermediate or Advanced AMD | DR Population- With or Without Diabetic Macular Edema

Israel

Clinical Trials on Leptomeningeal Disease (LMD)

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