Clinical Trials on Leukemia in Italy

Total 553 results

European Institute of Oncology

Terminated

R-2cda and Prolongation of Therapy With Rituximab Alone in Chronic Lymphocytic Leukaemia and Small Lymphocytic Lymphoma

Small Lymphocytic Lymphoma | Chronic Lymphocytic Leukaemia

Italy
Gruppo Italiano Studio Linfomi

Completed

Efficacy and Safety Study of Bendamustine With or Without Rituximab in Chronic Lymphoproliferative Disorders

Chronic Lymphocytic Leukaemia

Italy
Mundipharma Research Limited
Innovative Therapies For Children with Cancer Consortium

Terminated

Pharmacokinetic Study of Forodesine in Children With Relapsed or Refractory T-cell or B-cell Precursor Acute Lymphoblastic Leukaemia or T-cell Non- Hodgkin's Lymphoma. (BCX1777-108)

Relapsed or Refractory T-cell Acute Lymphoblastic Leukaemia | B-cell Precursor Acute Lymphoblastic Leukaemia | T-cell Non-Hodgkin's Lymphoma

Czech Republic, Austria, France, Germany, Italy, United Kingdom
University Hospital, Udine, Italy

Completed

Induction, Consolidation and Intensification Therapy for Patients Younger Than 66 Years With Previously Untreated CD33 Positive Acute Myeloid Leukemia (AML) (MYFLAI07)

Acute Myeloid Leukemia

Italy
Azienda Ospedaliera San Giovanni Battista

Unknown

Conventional and Experimental Chemotherapy With Allogeneic Transplant in Young Patients With Acute Myeloid Leukaemia (AML)

Acute Myeloid Leukemia

Italy
University of Bologna
Janssen-Cilag Ltd.

Unknown

Study to Assess the Safety, Tolerability, and Efficacy of Tipifarnib Plus Bortezomib in the Treatment of Acute Myeloid Leukemia (HEMOS AML 0106)

Acute Myeloid Leukemia

Italy
medac GmbH
Syneos Health; Celerion

Completed

Treosulfan-based Conditioning in Paediatric Patients With Haematological Malignancies

Myelodysplastic Syndromes (MDS) | Acute Lymphoblastic Leukaemias (ALL) | Acute Myeloid Leukaemias (AML) | Juvenile Myelomonocytic Leukaemias (JMML)

Germany, United Kingdom, Italy, Austria, Czechia, Poland
Ospedale Maggiore Di Trieste

Unknown

Hypomethylating Agents and Venetoclax in Newly Diagnosed Acute Myeloid Leukemia Patients Not Eligible for Intensive Chemotherapy

Acute Myeloid Leukemia, Adult | Hypomethylating Agents | Venetoclax

Italy
Associazione Italiana Ematologia Oncologia Pediatrica

Unknown

Treatment Study for Children and Adolescents With Acute Promyelocitic Leukemia

Acute Promyelocytic Leukemia

Italy
Fondazione Policlinico Universitario Agostino Gemelli...
Associazione Italiana per la Ricerca sul Cancro

Unknown

Up-front Hematopoietic Stem Cell Transplantation in Acute Myeloid Leukemia Patients Aged 65-75

Acute Myeloid Leukemia, Adult

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Observational Study in Adults With Imatinib-resistant/Intolerant Chronic Myeloid Leukemia Treated With Nilotinib (CML0609)

Chronic Myeloid Leukaemia

Italy
Azienda Socio Sanitaria Territoriale degli Spedali...

Recruiting

Next Generation Sequencing (NGS) in Familial Acute Myeloid Leukemia and Myelodisplastic Syndromes

Leukemia

Italy
University of Milano Bicocca

Completed

Validation of Digital-PCR Analysis Through Programmed Imatinib Interruption in PCR Negative CML Patients (ISAV)

Chronic Myeloid Leukemia

Canada, Germany, Israel, Italy, Spain
University of Bologna

Completed

Exploratory Study of IMATINIB High Dose in Intermediate Risk Chronic Myeloid Leukemia in Chronic Phase

Myeloid Leukemia, Chronic, Chronic-Phase

Italy
University of Bologna

Unknown

Adoptive Immunotherapy of High Risk Acute Myeloblastic Leukemia Patients Using Haploidentical Kir Ligand-mismatched Natural Killer Cells

Myeloblastic Leukemia

Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Unknown

INFUSION OF ALLOREACTIVE NATURAL KILLER (NK) CELLS AS CONSOLIDATION STRATEGY FOR ACUTE MYELOID LEUKEMIA PATIENTS (NKAML)

Adult Acute Myeloid Leukemia in Remission

Italy
Istituto Clinico Humanitas
Celgene

Unknown

Prevalence and Clinical Effect of IDH1/2 Mutations in Patients With Acute Myeloid Leukemia (Euro_IDH_AML)

Acute Myeloid Leukemia | IDH2 Gene Mutation | IDH1 Gene Mutation

Italy
Gruppo Italiano Studio Linfomi

Unknown

Prospective Collection of Biological Data of Prognostic Relevance in Patients With B-Cell Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia Stage A(0) | Chronic Lymphocytic Leukemia Stage A(I) | Chronic Lymphocytic Leukemia Stage A(II)

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Trial in AML Secondary to MPNs Patients, Unfit for Intensive Chemotherapy, Investigating a Treatment Combination Including Decitabine and Venetoclax (ENABLE)

Acute Myeloid Leukemia

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Venetoclax and Azacitidine for the Management of Molecular Relapse/Progression in Adult NPM1-mutated Acute Myeloid Leukemia

Acute Myeloid Leukemia | Acute Myeloid Leukemia, in Relapse | NPM1 Mutation

Italy
IRCCS SYNLAB SDN
Santobono-Pausilipon Hospital

Recruiting

Unravelling the Role of KCTD Protein Family in the Clinical Management of Childhood Acute Lymphoblastic Leukemias

Childhood Acute Lymphoblastic Leukemia

Italy
Italfarmaco

Terminated

Phase II Study of Histone-deacetylase Inhibitor ITF2357 in Refractory/Relapsed Lymphocytic Leukemia

Chronic Lymphocytic Leukemia

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Study on the Diagnosis and Management of CLL in Italy by GIMEMA

Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma | MBL-CLL - Monoclonal B-Cell Lymphocytosis Chronic Lymphocytic Leukaemia-Type

Italy
Oncology Institute of Southern Switzerland
Azienda Ospedaliero Universitaria Maggiore della Carita

Completed

A Prognostic Tool for Early Stage CLL

Chronic Lymphocytic Leukemia

Italy
University of Milano Bicocca
IRCCS San Raffaele

Completed

Allogeneic Stem Cell Transplantation in Chronic Myeloid Leukemia Failing TKIs Therapy

Leukemia | BCR-ABL Positive | Myelogenous | Chronic

Italy
Azienda Ospedaliera San Giovanni Battista

Unknown

Retrospective Evaluation of the Clinical Results Obtained in Patients With Acute Lymphoblastic Leukemia Treated at the San Giovanni Battista Hospital. (ALL)

Disease: Acute Lymphoblastic Leukemia

Italy
University of Rome Tor Vergata

Active, not recruiting

GilteRInf 2022 Study (Gilteritinib Related Infections) (GilteRInf)

Acute Myeloid Leukemia

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Unknown

AIDA 2000 Guidelines

Acute Promyelocytic Leukemia

Italy
Bambino Gesù Hospital and Research Institute

Recruiting

CD7-CAR-T Cells in Pediatric Relapsed/Refractory CD7+ T-ALL/LL (CD7-CAR01)

T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma

Italy
IRCCS SYNLAB SDN
Fondazione Santobono Pausilipon

Recruiting

Long Non-coding RNAs and Their Role on Epigenome as Diagnostic Markers in Childhood Acute Lymphoblastic Leukemia of T Cells.

Acute Lymphoblastic Leukemia, Pediatric

Italy
Università degli Studi di Brescia

Completed

Follow-up of Ph+ Chronic Myleoid Leukemia Patients in Complete Cytogenetic Response With Interferon Based Therapy

Chronic Myeloid Leukemia

Italy
Bambino Gesù Hospital and Research Institute

Recruiting

Allogeneic Second-generation CD19-CAR T Cells for Pediatric Relapsed/Refractory B-ALL

B-cell Acute Lymphoblastic Leukemia

Italy
A.O. Ospedale Papa Giovanni XXIII

Active, not recruiting

Blinatumomab Expanded T-cells (BET) in Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia (BET2017)

Indolent Non-Hodgkin Lymphomas/Chronic Lymphocytic Leukemia

Italy
Genzyme, a Sanofi Company

Completed

Vitalis Study - Observational Study on the Quality of Life in Patients Under Treatment for B-Chronic Lymphocytic Leukemia (B-CLL)

Leukemia, B-Cell, Chronic

Italy
University of Bologna
Novartis

Completed

Imatinib Standard Dose (400 mg/Day) Versus Imatinib High Dose (800 mg/Day) (CML022)

Chronic Myeloid Leukemia

Italy
IRCCS Burlo Garofolo

Recruiting

Anti-mullerian Hormone in Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia

Italy
University of Bologna

Unknown

My-HyperCVAD in the Treatment of Relapsed Refractory Adult Acute Lymphoid Leukemia

Lymphoid Leukemia

Italy
IRCCS Burlo Garofolo

Recruiting

Mercaptopurine Therapeutic Drug Monitoring to Optimize the Maintenance Phase of Childhood ALL

Acute Lymphoblastic Leukemia

Italy
University of Bologna

Unknown

Genotyping Analysis of Acute Lymphoblastic Leukemia (GALL)

Acute Lymphoblastic Leukemia | Adult

Italy
Niguarda Hospital

Recruiting

Midostaurin Associated With Standard Chemotherapy in Patients With Core-binding Factor Leukemia (AML FLT3)

Core Binding Factor Acute Myeloid Leukemia (CBF-AML)

Italy
Ciceri Fabio
Associazione Italiana per la Ricerca sul Cancro; Gruppo Italiano Trapianto...

Recruiting

Analysis of the Immunobiology of Acute Myeloid Leukemia Relapses After Allogeneic Hematopoietic Stem Cell Transplant (HSCT) for the Generation of Guidelines and Personalized Therapeutic Pathways (GITMO-RELAPSE)

Acute Myeloid Leukemia, in Relapse

Italy
Mariella Enoc

Completed

Trial to Assess the Efficacy of a TCR Alfa Beta Depleted Graft in Pediatric Affected by ALL or AML and Receiving an HSCT

Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Leukemia Acute Myeloid - AML

Italy
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Impact of Treatment With Targeted Therapies on the Generation of CAR T Cells in CLL Patients

Chronic Lymphocytic Leukemia | CLL

Italy
CANDONI ANNA
Gruppo Italiano Trapianto di Midollo Osseo

Completed

SCT in Ph Positive Acute Lymphoblastic Leukemia

Philadelphia Positive Acute Lymphoblastic Leukemia | SCT

Italy
University of Turin, Italy

Recruiting

Italian Treatment Free Remission Registry

Chronic Myeloid Leukemia | Treatment Free Remission

Italy
Università degli Studi di Brescia

Completed

Intermittent Imatinib Treatment in Chronic Myeloid Leukemia and Philadelphia Chromosome (Ph+CML) Patients Who Achieved a Complete Cytogenetic Response (CCgR) on Standard Imatinib Therapy (INTERIM0407)

Chronic Myeloid Leukemia

Italy
Azienda Ospedaliera Ospedale Infantile Regina Margherita...

Completed

A Multicentre, Retrospective Study to Evaluate the Outcome of HSCT Mismatch Unrelated Donors

Leukemia, Myeloid

Italy
Azienda Ospedaliera Città della Salute e della...

Recruiting

Evaluation of Infective Risk, Efficacy of Bacterial Prophylaxis and Validation of Sepsis Scores NEWS (National Early Warning Score) and qSOFA (Quick Sequential Organ Failure Assessment) in Patient With Acute Myeloid Leukemia Treated With Intensive Chemotherapy (LAM-SEPSIS)

Acute Myeloid Leukemia

Italy
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate and Total-Body Irradiation Before Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Leukemia

Chronic Lymphocytic Leukemia | Recurrent Small Lymphocytic Lymphoma | Prolymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Recurrent Chronic Lymphocytic Leukemia | T-Cell Prolymphocytic Leukemia | B-Cell Prolymphocytic Leukemia

United States, Italy
Sanofi

Terminated

Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia (ISLAY)

T-cell Type Acute Leukemia-Precursor | T-lymphoblastic Lymphoma/Leukaemia

Hungary, United States, Finland, France, Italy, Lithuania, Russian Federation

Clinical Trials on Leukemia in Italy

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