Clinical Trials on Liver and Biliary Tract Disorders in Duration of Pregnancy in United Kingdom

Total 8117 results

King's College Hospital NHS Trust
European Association for the Study of the Liver

Recruiting

Liver Disease in Pregnancy

Cirrhosis, Liver | HELLP Syndrome | Intrahepatic Cholestasis of Pregnancy | Pregnancy Disease | AFLP - Acute Fatty Liver of Pregnancy

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London

Unknown

Bile Acid Effects in Fetal Arrhythmia Study (BEATS)

Intrahepatic Cholestasis of Pregnancy | Cholestasis of Pregnancy | Obstetric Cholestasis

United Kingdom
University of Birmingham
University Hospital Birmingham NHS Foundation Trust; Intercept Pharmaceuticals

Terminated

EXerCise Intervention in cholesTatic LivEr Disease: The EXCITED Study (EXCITED)

Primary Biliary Cholangitis

United Kingdom
Light Chain Bioscience - Novimmune SA

Terminated

Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody (PIANO)

Primary Biliary Cirrhosis

Italy, United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust

Unknown

Paternally Inherited Phenotypes in Cholestasis (PIP-C)

Primary Sclerosing Cholangitis | Cholestasis | Primary Biliary Cirrhosis

United Kingdom
Wake Forest University Health Sciences

Completed

Surgical Outcomes Database For Faculty of Hepatopancreatic Biliary Surgery

Pancreatic Cancer | Biliary Tract Cancer | Cancer of Liver

United States
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom; Department of Health, United Kingdom

Completed

B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis (RITPBC)

Fatigue | Primary Biliary Cirrhosis

United Kingdom
Fast Forward Pharmaceuticals

Unknown

Pilot Study of FFP104 Dose Escalation in PBC Subjects

Primary Biliary Cirrhosis

Netherlands, United Kingdom
Imperial College London

Completed

The Metabolic Profile in Intrahepatic Cholestasis of Pregnancy and Diabetes Mellitus

Gestational Diabetes Mellitus | Intrahepatic Cholestasis of Pregnancy

United Kingdom
University of Alberta
GlaxoSmithKline; Axcan Pharma

Completed

Study of Combivir for Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States, Canada, United Kingdom
Perspectum

Completed

Repeatability and Reproducibility of Quantitative MRCP

Liver Diseases | Primary Sclerosing Cholangitis | Gallstones | Primary Biliary Cirrhosis

United Kingdom
Imperial College London

Active, not recruiting

Hypertensive Disorders of Pregnancy - the Neonatal Burden of Disease

Hypertension in Pregnancy

United Kingdom
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Repeat Doses of GSK2330672 Administration in Subjects With Primary Biliary Cirrhosis (PBC) and Symptoms of Pruritus

Cholestasis, Intrahepatic

United Kingdom
Albireo

Completed

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases

United Kingdom
Mirum Pharmaceuticals, Inc.

Terminated

A Placebo-controlled Study of Volixibat in Subjects With Elevated Serum Bile Acids Associated With Intrahepatic Cholestasis of Pregnancy (OHANA) (OHANA)

Intrahepatic Cholestasis of Pregnancy

United States, United Kingdom, New Zealand
California Pacific Medical Center Research Institute
University of California, Los Angeles; Northwestern University; University of...

Completed

EUS-Guided Rendezvous or Direct Interventions Versus Advanced ERCP Techniques for Biliary Access and Therapy

Disorders of Gallbladder | Disorders of Biliary Tract

United States
Genfit

Completed

Study to Evaluate the Efficacy and Safety of Elafibranor in Patients With Primary Biliary Cholangitis (PBC) and Inadequate Response to Ursodeoxycholic Acid

Primary Biliary Cholangitis (PBC)

United States, United Kingdom, France, Germany, Spain
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Contrast-enhanced MRI in Detecting Benign and Malignant Liver Lesions

Hepatocellular Carcinoma | Liver and Intrahepatic Bile Duct Disorder | Metastatic Malignant Neoplasm in the Liver | Primary Malignant Liver Neoplasm

United States
Stanford University

Unknown

Opiate Use and Biliary Dilation

Evaluation of Association Between Opiate Use and Biliary Dilation

United States
Mirum Pharmaceuticals, Inc.

Withdrawn

An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis (CASCADE)

Primary Biliary Cirrhosis

United States, United Kingdom
Intercept Pharmaceuticals

Completed

Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)

Liver Cirrhosis, Biliary

United States, France, Germany, Spain, United Kingdom, Canada, Austria
CymaBay Therapeutics, Inc.

Recruiting

An Open-Label Study Following Oral Dosing of Seladelpar to Subjects With Primary Biliary Cholangitis (PBC) and Hepatic Impairment (HI)

Hepatic Impairment | Compensated Cirrhosis | Primary Biliary Cholangitis

Korea, Republic of, United States, Spain, United Kingdom
CymaBay Therapeutics, Inc.

Completed

Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

United States, Germany, United Kingdom, Canada
Gilead Sciences

Terminated

Study to Evaluate the Safety, Tolerability, and Efficacy of Cilofexor in Adults With Primary Biliary Cholangitis Without Cirrhosis (PBC-Phase 2)

Primary Biliary Cholangitis

United States, Canada, Austria, United Kingdom
National Opinion Research Center
Chapin Hall at the University of Chicago; Office of Planning, Research & Evaluation and other collaborators

Completed

National Survey of Early Care and Education (NSECE)

Supply and Demand of Early Care and Education in the US

United States
M.D. Anderson Cancer Center

Recruiting

Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy

Metastatic Malignant Neoplasm in the Liver | Primary Malignant Liver Neoplasm | Liver and Intrahepatic Bile Duct Neoplasm

United States
Mirum Pharmaceuticals, Inc.

Completed

Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary Cirrhosis (CLARITY)

Primary Biliary Cirrhosis | PBC

United States, United Kingdom, Canada
Novartis Pharmaceuticals

Completed

A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients

Primary Biliary Cholangitis

United States, Germany, Russian Federation, Canada, United Kingdom, Poland
University of Florida

Terminated

The Role of Non-Alcoholic Fatty Liver Disease in Gestational Diabetes

Gestational Diabetes Mellitus in Pregnancy

United States
Manchester University NHS Foundation Trust
University of Manchester; National Institute for Health Research, United Kingdom

Active, not recruiting

Manchester Intermittent Diet in Gestational Diabetes Acceptability Study (MIDDAS-GDM)

Diabetes | Pregnancy Related | Gestational Diabetes | Gestational Diabetes Mellitus in Pregnancy | Intermittent Fasting | Diabetes in Pregnancy

United Kingdom
CymaBay Therapeutics, Inc.

Terminated

Study to Evaluate the Effects of Two Doses of MBX-8025 in Subjects With Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis (PBC)

Germany, United States, Canada, United Kingdom, Poland
Robert J. Porte
King's College Hospital NHS Trust; Universitaire Ziekenhuizen KU Leuven; Erasmus... and other collaborators

Completed

Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation (DHOPE-DCD)

End Stage Liver Disease | Liver Failure | Biliary Tract Diseases

Netherlands, Belgium, United Kingdom
University of Nottingham

Completed

A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy Volunteers

Sphincter of Oddi Dysfunction

United Kingdom
Intercept Pharmaceuticals

Active, not recruiting

Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBC

Primary Biliary Cholangitis

Netherlands, United Kingdom, Korea, Republic of, Germany, Australia, Estonia, Belgium, France, Czechia, Croatia, Greece, Hungary, Israel, Lithuania, Norway, Poland, Spain
Calliditas Therapeutics AB

Completed

Study to Assess Safety & Efficacy of GKT137831 in Patients With Primary Biliary Cholangitis Receiving Ursodiol.

Primary Biliary Cirrhosis

United States, Israel, Belgium, Germany, United Kingdom, Spain, Greece, Canada, Italy
Chelsea and Westminster NHS Foundation Trust

Recruiting

Effect of Obesity, Diabetes and Bariatric Surgery on Pregnancy Outcomes

Obesity | Pregnancy Complications | Pregnancy Related | Bariatric Surgery Status Complicating Pregnancy | Pregnancy in Diabetic

United Kingdom
Intercept Pharmaceuticals

Completed

Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis (POISE)

Primary Biliary Cirrhosis

United States, Spain, United Kingdom, Austria, Netherlands, Australia, Italy, Germany, Poland, Sweden, France, Canada, Belgium
University of California, Davis

Completed

Identification of Inflammatory and Fibrotic Biomarkers in PBC and NAFLD Patients

Primary Biliary Cirrhosis

United States
University of Texas Southwestern Medical Center

Completed

Oral Misoprostol for Labor Augmentation: A Pilot Study

Arrest of Dilation in Labor

United States
The Cleveland Clinic

Completed

Pentoxifylline for Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
Mayo Clinic

Active, not recruiting

Genetic Epidemiology of Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

United States
Mayo Clinic
UCB Pharma

Completed

Moexipril for Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
Intercept Pharmaceuticals
Syneos Health; Global PBC Study Group; Target RWE; UK PBC Group

Completed

Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (HEROES PBC)

Primary Biliary Cholangitis

United States
Christopher Bowlus, MD
Bristol-Myers Squibb

Completed

Study of Abatacept (Orencia) to Treat Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

United States
University of California, Davis
Genentech, Inc.

Completed

Initial Study of Rituximab to Treat Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
University of Florida
Shionogi Inc.; The PBCers Organization

Completed

Use of Fenofibrate for Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
University of Miami
Mayo Clinic

Withdrawn

Fenofibrate in Combination With Ursodeoxycholic Acid (UDCA) in Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
CymaBay Therapeutics, Inc.

Recruiting

Seladelpar in Subjects With Primary Biliary Cholangitis (PBC)

Primary Biliary Cirrhosis

United States, Korea, Republic of, Belgium, Spain, France, Switzerland, Romania, United Kingdom, Austria, Israel, Australia, Argentina, Canada, Chile, Germany, Greece, Hungary, Italy, Mexico, Netherlands, Poland, Czechia, New Zealand, Turke... and more
Intercept Pharmaceuticals

Terminated

Study of INT 747 in Combination With URSO in Patients With Primay Biliary Cirrhosis (PBC)

Liver Cirrhosis, Biliary

United States, Spain, Canada, United Kingdom, France, Germany, Austria, Netherlands
Kowa Research Institute, Inc.

Recruiting

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Primary Biliary Cholangitis

United States, Japan

Clinical Trials on Liver and Biliary Tract Disorders in Duration of Pregnancy in United Kingdom

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