Clinical Trials on Locally Advanced (Unresectable) or Metastatic Solid Tumor Malignancies
Total 953 results
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National Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid... and other conditionsUnited States, Puerto Rico
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BiocadRecruitingMelanoma | Melanoma (Skin) | Melanoma Stage IV | Melanoma Stage III | Melanoma Metastatic | Melanoma Unresectable | Melanoma AdvancedIndia, Russian Federation, Belarus
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NKGen Biotech, Inc.Affimed GmbHTerminatedCarcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Squamous Cell Carcinoma of Head and Neck | Advanced Solid Tumor | Metastatic Tumor | Refractory TumorUnited States
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AstraZenecaCompletedLocally Advanced or Metastatic Prostate Cancer.Greece
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National Cancer Institute (NCI)Active, not recruitingMetastatic Melanoma | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid NeoplasmUnited States
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EMD SeronoMerck KGaA, Darmstadt, GermanyCompletedN-Ras Mutated Locally Advanced or Metastasis Malignant Cutaneous MelanomaUnited States, Sweden, Australia, France, Italy, South Africa, Spain, United Kingdom, Germany, Netherlands, Israel, New Zealand, Belgium, Switzerland
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Consorzio OncotechClinical Research Technology S.r.l.UnknownBreast Cancer | Metastatic Breast Cancer | Hormone Receptor Positive Tumor | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast | Locally Advanced Malignant NeoplasmItaly
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Suzhou Suncadia Biopharmaceuticals Co., Ltd.Enrolling by invitationPerioperative Treatment in Subjects With Locally Advanced Resectable Gastric Cancer or Gastroesophageal Junction CancerChina
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Grupo Español de Tumores Huérfanos e InfrecuentesTakedaTerminatedMetastatic or Advanced Non-resectable Granulosa Cell Ovarian TumorsSpain
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National Cancer Institute (NCI)SuspendedLocally Advanced Uterine Corpus Leiomyosarcoma | Metastatic Uterine Corpus Leiomyosarcoma | Stage III Uterine Corpus Leiomyosarcoma AJCC v8 | Stage IV Uterine Corpus Leiomyosarcoma AJCC v8 | Unresectable Uterine Corpus LeiomyosarcomaUnited States, Puerto Rico
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David Liebner, MDWithdrawnLocally Advanced Leiomyosarcoma | Metastatic Leiomyosarcoma | Unresectable Leiomyosarcoma | Stage III Retroperitoneal Sarcoma AJCC v8 | Stage IIIA Retroperitoneal Sarcoma AJCC v8 | Stage IIIB Retroperitoneal Sarcoma AJCC v8 | Stage IV Retroperitoneal Sarcoma AJCC v8United States
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National Cancer Institute (NCI)WithdrawnLocally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Aggressive Non-Hodgkin Lymphoma | Indolent Non-Hodgkin LymphomaUnited States
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National Cancer Institute (NCI)RecruitingMetastatic Merkel Cell Carcinoma | Refractory Merkel Cell Carcinoma | Locally Advanced Merkel Cell Carcinoma | Unresectable Merkel Cell Carcinoma | Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8United States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)WithdrawnMetastatic Adrenal Gland Pheochromocytoma | Stage III Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Locally Advanced Adrenal Gland Pheochromocytoma | Locally Advanced Paraganglioma | Metastatic Paraganglioma | Metastatic Parathyroid Gland Carcinoma and other conditionsUnited States
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ModernaTX, Inc.TerminatedOvarian Cancer | Relapsed/Refractory Solid Tumor Malignancies or LymphomaUnited States
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H. Lee Moffitt Cancer Center and Research InstituteReliable Cancer TherapiesTerminatedPain | Lymphoma | Cancer | Neoplasm Metastasis | Multiple Myeloma | Hematologic Malignancy | Tumor | Unresectable Malignant Neoplasm | Malignant Solid TumorUnited States
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Servier Bio-Innovation LLCInstitut de Recherches Internationales ServierNot yet recruitingLocally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen
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Antengene (Hangzhou) Biologics Co., Ltd.RecruitingAdvanced Solid Tumor | Metastatic Solid Tumor | Mature B-cell Non-Hodgkin LymphomaChina
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Antengene Biologics LimitedRecruitingAdvanced Solid Tumor | Metastatic Solid Tumor | Mature B-cell Non-Hodgkin LymphomaUnited States, Australia
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NantCell, Inc.TakedaTerminatedCancer | Pancreatic Cancer | Advanced Solid Tumors | Metastatic Cancer | Bone Metastases | Solid Tumors | Pancreas Cancer | Adenocarcinoma of the Pancreas | Oncology | Cancer of Pancreas | Metastatic Pancreatic Cancer | Metastases | Cancer of the Pancreas | Advanced Malignancy | Oncology Patients | Endocrine CancerItaly, Spain, United Kingdom, Belgium, Canada, Denmark, Romania, United States, Germany, Netherlands, Korea, Republic of, Russian Federation, Australia, Austria, Lithuania, Portugal, Greece, Poland, Switzerland, Serbia, Bulgaria, ... and more
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National Cancer Institute (NCI)Active, not recruitingMetastatic Urothelial Carcinoma | Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 | Stage IV Bladder Urothelial Carcinoma AJCC v7 | Locally Advanced Urothelial Carcinoma | Recurrent Urothelial Carcinoma | Unresectable Urothelial Carcinoma | Advanced Urothelial CarcinomaUnited States
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Nanjing First Hospital, Nanjing Medical UniversityRecruitingAdvanced or Metastatic Paraganglioma/ PheochromocytomaChina
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Zai Lab (Shanghai) Co., Ltd.TerminatedUnresectable, Recurrent or Metastatic Melanoma | Untreated Mucosal or Acral Lentiginous MelanomaChina
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National Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Castration-Resistant Prostate Carcinoma and other conditionsUnited States
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Peking Union Medical College HospitalNot yet recruitingLocally Advanced or Metastatic Radioiodine-refractory Differentiated Thyroid CarcinomaChina
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Taiho Oncology, Inc.Quintiles, Inc.; United BioSource, LLCCompletedLocally Advanced or Metastatic Pancreatic Cancer
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AB ScienceCompletedLocally Advanced or Metastatic Pancreatic CancerFrance, Belgium, Greece, India, Russian Federation, Slovakia, Tunisia, Ukraine
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Angiex, Inc.RecruitingCancer | Pancreatic Adenocarcinoma | Triple Negative Breast Cancer | Metastatic Solid Tumor | Advanced Cancer | Pancreas Cancer | Locally Advanced CarcinomaUnited States
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PfizerCompletedSolid Tumor and Hematologic MalignanciesUnited States
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Thomas Jefferson UniversityNot yet recruitingLocally Advanced Unresectable Uveal MelanomaUnited States
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Prelude TherapeuticsRecruitingAdvanced Solid Tumor | Metastatic Solid Tumor | Non-small Cell Lung Cancers | SMARCA4 Gene MutationUnited States, France, Spain, Singapore, Netherlands
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Alliance for Clinical Trials in OncologyWithdrawnMetastatic Uveal Melanoma | Advanced Uveal Melanoma | Unresectable Uveal Melanoma
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NiKang Therapeutics, Inc.RecruitingSmall Cell Lung Carcinoma | Gastric Cancer | Ovarian Neoplasms | Ovarian Cancer | Solid Tumor | Endometrial Neoplasms | Triple Negative Breast Cancer | Triple Negative Breast Neoplasms | Advanced Solid Tumor | Endometrial Cancer | Small-cell Lung Cancer | Platinum-resistant Ovarian Cancer | Ovarian Carcinoma | Solid... and other conditionsUnited States
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Baxalta now part of ShireCompletedMalignant Solid Tumors | Metastatic Adenocarcinoma of the Colon or RectumGermany, United States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Skin Squamous Cell Carcinoma | Unresectable Solid Neoplasm | Metastatic Kidney Medullary Carcinoma | Metastatic Penile Carcinoma | Small Cell Carcinoma | Metastatic Adrenal Gland Pheochromocytoma | Stage IV Penile Cancer... and other conditionsUnited States
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Shandong Suncadia Medicine Co., Ltd.Enrolling by invitationMetastatic or Local Advanced Breast Cancer of PatientsChina
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Pasithea Therapeutics Corp.RecruitingAdvanced Solid Tumors | RAS Mutation | NF1 Mutation | RAF MutationUnited States
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Targovax OyCompletedAdvanced or Unresectable Melanoma Progressing After PD1 BlockadeUnited States, Norway
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National Health Research Institutes, TaiwanNational Taiwan University Hospital; China Medical University Hospital; Chang... and other collaboratorsUnknownLocally Advanced or Metastatic Pancreatic CancerTaiwan
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BeyondBio Inc.UnknownLocally Advanced or Metastatic Pancreatic CancerKorea, Republic of
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FibroGenCompletedLocally Advanced or Metastatic Pancreatic CancerUnited States
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AstraZenecaCompletedLINE: Treatment Patterns in postmenopausaL Women With Hormone Receptor Positive Breast Cancer (LINE)Local Advanced or Metastatic Postmenopausal Breast CancerRussian Federation
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National Cancer Institute (NCI)Active, not recruitingStage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Pancreatic Adenocarcinoma | Metastatic... and other conditionsUnited States
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Bristol-Myers SquibbCompletedAdvanced or Metastatic MelanomaUnited States
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Sheba Medical CenterRambam Health Care Campus; AstraZeneca; Tel-Aviv Sourasky Medical CenterRecruitingMetastatic or Locally Advanced NSCLCIsrael
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National Cancer Institute (NCI)RecruitingColorectal Neoplasms | Advanced Breast Cancer | Advanced Solid Tumors | Malignant Peripheral Nerve Sheath Tumor | Metastatic Pancreatic Cancer | Pediatric Solid TumorUnited States
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National University Hospital, SingaporeRecruitingAdvanced Refractory Solid Tumors | Advanced Triple Negative Breast Cancers | Metastatic Triple Negative Breast CancersSingapore
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Rainier TherapeuticsTerminatedUrinary Bladder Disease | Locally Advanced or Metastatic Urothelial Cell Carcinoma | Urological DiseasesUnited States, Spain, Belgium, France, Germany, Italy, Korea, Republic of, Turkey, Hungary, Netherlands, Serbia, Poland, Russian Federation, Sweden, Moldova, Republic of, Denmark, Ukraine
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Rainier TherapeuticsTerminatedUrinary Bladder Disease | Locally Advanced or Metastatic Urothelial Cell Carcinoma | Urological DiseasesItaly, Spain, United States, Korea, Republic of, Turkey, Taiwan, Sweden, Czechia, United Kingdom
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Fred Hutchinson Cancer CenterAmazon.com Services LLCRecruitingAnatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Cutaneous Melanoma | Unresectable Cutaneous Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC... and other conditionsUnited States