Clinical Trials on Locally Recurrent Cancer

Total 56589 results

Baylor College of Medicine
National Institute on Minority Health and Health Disparities (NIMHD)

Enrolling by invitation

Prospective Evaluation of Self-Testing to Increase Screening (PRESTIS)

Cervical Cancer | Human Papillomavirus Infection

United States
University of Oxford
British HIV Association (BHIVA)

Completed

Re-Evaluation of Annual Cytology Using HPV Testing to Upgrade Prevention in Women Living With HIV (REACH-UP)

HIV Infections | Cervical Cancer | HPV Infection

United Kingdom
Massachusetts General Hospital
National Cancer Institute (NCI)

Completed

Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblastoma or Pineoblastoma

Brain and Central Nervous System Tumors | Long-term Effects Secondary to Cancer Therapy in Children

United States
National Cancer Institute (NCI)

Completed

Association Between Hepatitis C Virus Infection and Hematologic and Thyroid Cancers

Hepatitis C Virus

United States
Duke University

Terminated

Accuracy of Portable Colposcopy and HPV Genotypes Among HIV+ Women

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus

Haiti
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin

Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Teratoma | Extragonadal Germ Cell Tumor

United States
University of California, San Francisco
National Cancer Institute (NCI)

Completed

Celecoxib in Preventing Basal Cell Carcinoma in Patients With Basal Cell Nevus Syndrome

Non-melanomatous Skin Cancer

United States
Kindai University

Unknown

Prediction of Incidence of Liver Cancer by Use of Real-time Tissue Elastography (PICTURE)

Chronic Hepatitis B | Chronic Hepatitis C

Japan
VA Office of Research and Development

Completed

Mobile Intervention for Veterans With PTSD and Anger

Anger | Posttraumatic Stress Disorder

United States
InferLink Corporation
University of California, Los Angeles; Duke University

Completed

Mobile Health Application for Family and Behavioral Health Provider Communication

Anger | Posttraumatic Stress Disorder

United States
Fusion Pharmaceuticals Inc.
AstraZeneca

Not yet recruiting

A Phase 1, Dose-escalation Study of [225Ac]-FPI-2068 in Adult Patients With Advanced Solid Tumours

Advanced Solid Tumor | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Metastatic Colorectal Carcinoma

United States, Canada
Shanghai Jiao Tong University School of Medicine

Recruiting

Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001)

Medullary Thyroid Cancer | Pancreatic Neuroendocrine Tumor | Adrenal Cortical Carcinoma | Thymic Neuroendocrine Carcinoma

China
Universiteit Antwerpen
Sciensano; Antwerp University Hospital (UZA); Centre for Cancer Detection (CvKO)

Recruiting

Cervical Cancer Screening Based on First-void Urine Self-sampling to Reach un(Der)-Screened Women: ScreenUrSelf Trial (ScreenUrSelf)

Cervical Intraepithelial Neoplasia | Cervix Cancer | HPV-Related Cervical Carcinoma | Human Papilloma Virus

Belgium
Krystal Biotech, Inc.

Recruiting

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

Cancer | Carcinoma, Squamous Cell | Carcinoma, Basal Cell | Osteosarcoma | Cutaneous Melanoma | Melanoma Stage IV | Melanoma Stage III

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Improving Response to Immunotherapy in Patients With Advanced Hepatocellular Carcinoma and Chronic Hepatitis C Virus Infection With Direct-Acting Antiviral Therapy

Liver Cancer

United States
The Netherlands Cancer Institute

Recruiting

Primary Cytoreductive Surgery With or Without Hyperthermic Intraperitoneal Chemotherapy (HIPEC) (OVHIPEC-2)

Ovarian Cancer

Netherlands, United States, France, Denmark, Italy, Sweden, Ireland
Megan Daly, MD
Merck Sharp & Dohme LLC

Recruiting

UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade

Metastatic Renal Cell Carcinoma | Non Small Cell Lung Cancer | Metastatic Melanoma | Head and Neck Squamous Cell Carcinoma

United States
Corcept Therapeutics
Gynecologic Oncology Group

Active, not recruiting

Relacorilant in Combination With Nab-Paclitaxel in Advanced, Platinum-Resistant, High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian-Tube Cancer

Fallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Neoplasm

United States, Argentina, Australia, Belgium, Brazil, Canada, France, Hungary, Israel, Italy, Korea, Republic of, Poland, Spain, United Kingdom
Merck Sharp & Dohme LLC

Active, not recruiting

Pembrolizumab/Placebo Plus Paclitaxel With or Without Bevacizumab for Platinum-resistant Recurrent Ovarian Cancer (MK-3475-B96/KEYNOTE-B96/ENGOT-ov65)

Fallopian Tube Neoplasms | Carcinoma, Ovarian Epithelial | Ovarian Cancer

United States, Germany, Israel, Canada, China, Australia, Belgium, Brazil, Chile, Colombia, Denmark, Finland, France, Ireland, Italy, Japan, Korea, Republic of, Mexico, Netherlands, New Zealand, Norway, Poland, Russian Federation, Turkey and more
Merck Sharp & Dohme LLC

Completed

A Study to Evaluate the Immunogenicity, Safety and Tolerability of Quadrivalent Human Papillomavirus Vaccine (V501) in Chinese Girls Aged 9-19 Years and Young Women Aged 20-26 Years (V501-213)

Prevention of HPV Types 16- and 18-related Cervical Cancer, Cervical Intraepithelial Neoplasia (CIN) 1/2/3, and Cervical Adenocarcinoma in Situ

China
Dana-Farber Cancer Institute
National Cancer Institute (NCI)

Completed

Stepping Into Survivorship: Harnessing Behavioral Economics to Improve Quality of Life in Ovarian Cancer

Ovarian Cancer

United States
Sarah E Taylor
American Society of Clinical Oncology

Terminated

Delayed Initiation of Olaparib Maintenance Therapy in Platinum Sensitive Recurrent Ovarian Cancer

Ovarian Cancer

United States
Shanghai Zerun Biotechnology Co.,Ltd
Walvax Biotechnology Co., Ltd.

Active, not recruiting

Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9

Cervical Cancer | Papillomavirus Infections | CIN | Genital Wart | VIN

China
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer

Testicular Germ Cell Tumor | Ovarian Cancer | Brain and Central Nervous System Tumors | Teratoma | Extragonadal Germ Cell Tumor

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastatic Prostate Cancer

Prostate Cancer | Brain and Central Nervous System Tumors

United States, Spain
Merck Sharp & Dohme LLC

Completed

Caelyx in Ovarian Cancer: Prevention and Treatment of Infusion Reactions and Palmar-plantar Erythrodysesthesia (Study P04085)(COMPLETED)

Ovarian Neoplasms
University Hospital, Bonn

Unknown

Safety and Pharmacokinetics of Intraoperative Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) With Cisplatin to Treat Platinum-sensitive Recurrent Ovarian Cancer (HIPEC ROC I)

Ovarian Cancer

Germany
Chinese Academy of Medical Sciences, Fuwai Hospital

Recruiting

Cardiac Magnetic Resonance for Risk Stratification in Dilated Cardiomyopathy

Dilated Cardiomyopathy | Single-center Study

China
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Patients With Acute Myeloid Leukemia in Remission

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia in Remission | Myelodysplastic Syndrome With Excess Blasts | Adult Acute Monocytic Leukemia | Adult Acute Myeloid Leukemia With Inv(16)(p13.1q22); CBFB-MYH11 and other conditions

United States, Israel, Peru
National Cancer Institute (NCI)

Completed

Tipifarnib in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Acute Myeloid Leukemia With Multilineage Dysplasia Following Myelodysplastic Syndrome | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic... and other conditions

United States
National Cancer Institute (NCI)

Completed

Busulfan, Fludarabine Phosphate, and Anti-Thymocyte Globulin Followed By Donor Stem Cell Transplant and Azacitidine in Treating Patients With High-Risk Myelodysplastic Syndrome and Older Patients With Acute Myeloid Leukemia

Acute Myeloid Leukemia | Recurrent Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Myelodysplastic Syndrome With Excess Blasts | Secondary Myelodysplastic Syndrome | de Novo Myelodysplastic Syndrome | Adult Acute Monoblastic Leukemia | Adult Acute Monocytic Leukemia | Adult Acute Myeloid Leukemia... and other conditions

United States
OHSU Knight Cancer Institute
Novartis Pharmaceuticals; Oregon Health and Science University

Completed

Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma

Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Adult Rhabdomyosarcoma | Adult Alveolar Soft Part Sarcoma | Adult Angiosarcoma | Adult Desmoplastic Small Round Cell Tumor | Adult Epithelioid Hemangioendothelioma | Adult Epithelioid Sarcoma | Adult Extraskeletal Myxoid Chondrosarcoma | Adult Extraskeletal... and other conditions

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Terminated

Yoga Therapy in Treating Patients With Malignant Brain Tumors

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Oligodendroglioma | Adult Pineal Gland Astrocytoma | Recurrent Adult... and other conditions

United States
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI); Children's Hospital of Michigan

Terminated

Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer

Unspecified Childhood Solid Tumor, Protocol Specific | Osteosarcoma | Neuroblastoma | Retinoblastoma | Recurrent/Refractory Childhood Hodgkin Lymphoma | Wilms Tumor and Other Childhood Kidney Tumors | Childhood Choroid Plexus Tumor | Childhood Soft Tissue Sarcoma | Childhood Medulloblastoma | Childhood... and other conditions

United States
Northwestern University

Terminated

Metformin+Cytarabine for the Treatment of Relapsed/Refractory AML

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Guardant Health, Inc.

Recruiting

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation (ORACLE)

Renal Cell Carcinoma | Pancreatic Adenocarcinoma | Gastric Adenocarcinoma | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer | Fallopian Tube Carcinoma | Endometrial Carcinoma | Bladder Carcinoma | Esophageal Carcinoma | Invasive Breast Carcinoma | Cutaneous Melanoma | Epithelial Ovarian... and other conditions

United States
Checkpoint Therapeutics, Inc.
Novotech (Australia) Pty Limited

Recruiting

Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers

Melanoma | Renal Cell Carcinoma | Head and Neck Cancer | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Non Hodgkin Lymphoma | Endometrial Cancer | Carcinoma, Small Cell | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Malignant Mesothelioma, Advanced

Australia, New Zealand, Thailand, Ukraine, Spain, Russian Federation, France, Poland, South Africa
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Active, not recruiting

Cancer and Blood Pressure Management, CARISMA Study

Metastatic Renal Cell Carcinoma | Chronic Kidney Disease | Stage IV Renal Cell Cancer AJCC v8 | Cardiovascular Disorder | Metastatic Thyroid Gland Medullary Carcinoma | Stage IV Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVA Thyroid Gland Medullary Carcinoma AJCC v8 | Stage IVB Thyroid Gland... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord

Sarcoma | Metastatic Melanoma | Thyroid Gland Carcinoma | Metastatic Malignant Neoplasm of Unknown Primary | Spinal Cord Compression | Stage IV Breast Cancer AJCC v6 and v7 | Malignant Digestive System Neoplasm | Metastatic Malignant Neoplasm in the Spine | Metastatic Kidney Carcinoma | Metastatic Head... and other conditions

United States
OHSU Knight Cancer Institute
National Cancer Institute (NCI)

Terminated

Blood Samples From Patients on a Clinical Trial to CINV During HSCT

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms | Nausea and Vomiting

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Campath-1H + FK506 and Methylprednisolone for GVHD

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host...

United States
H. Lee Moffitt Cancer Center and Research Institute

Recruiting

The Pancreas Interception Center (PIC) for Early Detection, Prevention, and Novel Therapeutics

Lynch Syndrome | Pancreatic Ductal Adenocarcinoma | Chronic Pancreatitis | Pancreatic Cyst | Ataxia Telangiectasia | FAP | Peutz-Jeghers Syndrome | PALB2 Gene Mutation | BRCA Mutation | Fatty Pancreas | Genetic Pancreatic Cancer | Genetic Pancreatitis | Familial Atypical Multiple Mole-Melanoma

United States
University of Wisconsin, Madison
National Institute on Aging (NIA); Arizona State University

Not yet recruiting

Speech Pattern Evaluation and Analysis for Knowledge of AD (SPEAK-AD)

Wisconsin Alzheimer's Disease Research Center | Wisconsin Registry for Alzheimer's Prevention

United States
Hospital Universitario Virgen de la Arrixaca

Not yet recruiting

Liver Transplantation for Unresectable GIST Liver Metastases (TRANSGIST)

Liver Diseases | Liver Transplantation | Liver Neoplasms | Gastrointestinal Stromal Tumors | Metastasis | Liver Metastases | Liver Transplant; Complications | Liver Cancer | Liver Transplant Disorder | Liver Carcinoma | GIST, Malignant | GIST | Metastases | Metastatic Liver Cancer | Gastrointestinal Stromal Tumor of... and other conditions

Spain
British Columbia Cancer Agency

Recruiting

DOTATOC PET/CT for Imaging NET Patients

Pituitary Adenoma | Neuroendocrine Tumors | Medulloblastoma | Small-cell Lung Cancer | Neuroblastoma | Meningioma | Merkel Cell Carcinoma | Pheochromocytoma | Paraganglioma | Gastrinoma | Glucagonoma | Insulinoma | Vipoma | Carcinoid | Ganglioneuroma | Medullary Carcinoma

Canada
Barbara Ann Karmanos Cancer Institute
National Cancer Institute (NCI)

Completed

Aprepitant, Granisetron, & Dexamethasone in Preventing Nausea & Vomiting in Pts. Receiving Cyclophosphamide Before a Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms | Nausea and Vomiting

United States
University of Aarhus

Not yet recruiting

Dysphagia and Quality of Life in Patients With Oral Squamous Cell Carcinoma Before and After Treatment

Quality of Life | Dysphagia | Oral Cavity Cancer

Denmark
Pure Biologics S.A.
Presage Biosciences

Recruiting

A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors

Triple Negative Breast Cancer | Head and Neck Squamous Cell Carcinoma | Soft Tissue Sarcoma Adult

United States
Yandi Zhu

Recruiting

Study on Symptom Clusters During Chemotherapy in Ovarian Cancer Patients With Different Chinese Medicine Constitution

Ovarian Cancer | Radiotherapy Side Effect | Symptom Cluster

China
University Ghent
Universidade Nova de Lisboa; Horizon 2020 - European Commission; Hospital de... and other collaborators

Recruiting

ELEVATE Acceptability Study (ELEVATE AS)

Cervical Cancer | HPV Infection | Acceptability of Health Care

Belgium, Brazil, Ecuador, Portugal

Clinical Trials on Locally Recurrent Cancer

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Gabon

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations