Clinical Trials on Low Grade Astrocytomas

Total 8568 results

Centre Oscar Lambret
National Cancer Institute, France; Pierre Fabre Laboratories

Completed

Phase II Trial of Oral Vinorelbine in Children With Recurrent or Progressive Unresectable Low-Grade Glioma (OVIMA-1210)

Low-Grade Glioma

France
National Cancer Institute (NCI)
NRG Oncology

Active, not recruiting

Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents

Ovarian Seromucinous Carcinoma | Recurrent Ovarian High Grade Serous Adenocarcinoma | Recurrent Platinum-Resistant Ovarian Carcinoma | Fallopian Tube Mucinous Adenocarcinoma | Recurrent Fallopian Tube Clear Cell Adenocarcinoma | Recurrent Fallopian Tube Endometrioid Adenocarcinoma | Recurrent... and other conditions

United States, Puerto Rico
Coordinación de Investigación en Salud, Mexico

Recruiting

Acetic Acid for the Detection of Esophageal Neoplasms

Intestinal Metaplasia | Dysplasia | Barretts Esophagus With Low Grade Dysplasia

Mexico
Beijing Sanbo Brain Hospital

Completed

Study of Recombinant Human Endostatin Combined With CV Regimen in the Treatment of Pediatric Low-grade Gliomas

Low-grade Glioma | Pediatric Brain Tumor

China
European Organisation for Research and Treatment...
Cooperative Trials Group for Neuro-Oncology (COGNO)

Terminated

Trial in Low Grade Glioma Patients: Wait or Treat (IWOT)

Temozolomide | Low-grade Glioma | Phase III | Wait or Treat

Spain, Australia, Switzerland, France, Belgium, Italy, Austria, Netherlands, United Kingdom, Denmark
Case Comprehensive Cancer Center
Burkhardt Brain Tumor and Neuro-Oncology Center

Recruiting

Prospective Surgical Study on the Pattern of Electrical Activity in High Grade Glioma as a Predictor of Progression

Glioblastoma | High Grade Glioma

United States
CCTU- Cancer Theme
Cambridge University Hospitals NHS Foundation Trust; Cancer Research UK; Experimental...

Active, not recruiting

Predicting Sites of Tumour Progression in the Invasive Margin of Glioblastomas (PRaM-GBM Study) (PRaM-GBM)

High Grade Glioma

United Kingdom
Northern Sydney and Central Coast Area Health Service
Merck KGaA, Darmstadt, Germany

Unknown

Temozolomide and Procarbazine With Cilengitide for Patients With Glioblastoma Multiforme Without Methylation of the MGMT Promoter Gene (ExCentric)

Newly Diagnosed Non Methylated Glioblastoma Multiforme Grade 4

Australia
University Hospital, Montpellier

Completed

Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas (SPECIFY)

Low-grade Glioma

France
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Lei Li

Unknown

DNA Methylation for Screening Uterine Cervical Lesions: A Case-control Study

DNA Methylation | Uterine Cervical Cancer | High Grade Squamous Intraepithelial Lesions | Low Grade Squamous Intraepithelial Lesions

China
Oblato, Inc.

Recruiting

Study of Safety and Pharmacokinetic Properties of Oral OKN-007 in Patients With Recurrent High-Grade Glioma

Astrocytoma | Glioblastoma Multiforme | Oligodendroglioma | High-grade Glioma

United States
University Hospital, Strasbourg, France

Recruiting

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy (PLGG - MEKTRIC)

Pleomorphic Xanthoastrocytoma | Grade 1 Glioma | Mixed Glio-neuronal Tumors

France
Methodist Healthcare

Terminated

Gliadel Wafer, Temozolomide and Radiation Therapy for Newly Diagnosed GBM

Glioblastoma Multiforme | High-Grade Glioma

United States
Turku University Hospital

Completed

Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas (RODIG)

Malignant Glioma | Low Grade Glioma

Finland
Tilburg University

Completed

Effects of Exercise on Cognitive Function in Glioma Patients

Low Grade Glioma of Brain | Anaplastic Glioma of Brain

Netherlands
Celgene
Stanford University

Terminated

VTX-2337 in Combination With Radiotherapy in Patients Low-Grade B-cell Lymphomas

Low Grade B Cell Lymphoma

United States
Massachusetts General Hospital
National Cancer Institute (NCI); Dana-Farber Cancer Institute

Active, not recruiting

Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation

Astrocytoma | Brain Tumor | Ependymoma | Ganglioglioma | Low Grade Glioma

United States
Northwest Biotherapeutics

Active, not recruiting

Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer (GBM)

Glioma | Glioblastoma | Brain Cancer | Brain Tumor | Glioblastoma Multiforme | GBM | Grade IV Astrocytoma

United States, Germany, Canada, United Kingdom
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); American Lebanese Syrian Associated Charities...

Recruiting

A Trial of Dabrafenib, Trametinib and Hydroxychloroquine for Patients With Recurrent LGG or HGG With a BRAF Aberration

Low Grade Glioma (LGG) of Brain With BRAF Aberration | High Grade Glioma (HGG) of the Brain With BRAF Aberration | Low Grade Glioma of Brain With Neurofibromatosis Type 1

United States
Nader Sanai
Barrow Neurological Institute; Ivy Brain Tumor Center

Recruiting

Superselective Intra-arterial Cerebral Infusion of Temsirolimus in HGG

Glioma | Glioblastoma | High Grade Glioma | Glioma, Malignant

United States
Exelixis

Completed

Study of Multiple Doses and Regimens of XL184 (Cabozantinib) in Subjects With Grade IV Astrocytic Tumors in First or Second Relapse

Astrocytic Tumors

United States, Canada
Gloucestershire Hospitals NHS Foundation Trust

Suspended

Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease (Vulval VS)

Lichen Sclerosus | Squamous Cell Carcinoma | Normal Vulval Skin | High Grade Dysplasia - Usual Type ('VIN 2-3') | High Grade Dysplasia - Differentiated Type ('VIN 2-3') | Epithelial Hyperplasia Without Atypia | Atypia Not Otherwise Specified/ Low Grade Dysplasia ('VIN 1') | Pagets Disease of the...

United Kingdom
National Cancer Institute (NCI)

Completed

SGN-00101 Vaccine in Treating Human Papillomavirus in Patients Who Have Abnormal Cervical Cells

Cervical Cancer | High-grade Squamous Intraepithelial Lesion | Atypical Squamous Cells of Undetermined Significance | Low-grade Squamous Intraepithelial Lesion

United States
National Cancer Institute (NCI)

Active, not recruiting

Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations

Glioblastoma | WHO Grade 3 Glioma | Advanced Malignant Solid Neoplasm | Recurrent Malignant Solid Neoplasm | Recurrent Glioma | Recurrent Cholangiocarcinoma | WHO Grade 2 Glioma

United States
Future Biome SA

Recruiting

Fungal Fiber for Gut Health (FUN4GUT)

Immune Response | Stress | Nutrition, Healthy | Gut Microbiome | Low-grade Chronic Inflammation | Activity of Daily Living | Gut Health | Mild Gastrointestinal Symptoms in Healthy Adults | Gut Permeability

Argentina
Day One Biopharmaceuticals, Inc.
Pacific Pediatric Neuro-Oncology Consortium

Recruiting

A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors (FIREFLY-1)

Advanced Solid Tumor | Low-grade Glioma

United States, Israel, Korea, Republic of, Denmark, Singapore, Netherlands, Canada, Australia, Germany, Switzerland, United Kingdom
University of California, San Francisco
Merck Sharp & Dohme LLC

Terminated

Ovarian Aging in Low Grade Glioma (LGG) Treated With Temozolomide (OVA-LGG)

Low Grade Glioma

United States
National Health Research Institutes, Taiwan

Completed

A Multi-center Survey of HPV in Cervical Intraepithelial Neoplasia (CIN) With Longitudinal Follow-up of LSIL Cases

Cervical Cancer | Human Papillomavirus | Low-grade Squamous Intraepithelial Lesion,

Taiwan
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Terminated

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

Glioblastoma | Gliosarcoma | Ependymoma | Anaplastic Astrocytoma | Oligodendroglioma | Anaplastic Ependymoma | Giant Cell Glioblastoma | Astrocytoma, Grade II | Brainstem Tumors

United States
National Cancer Institute (NCI)

Completed

Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary Gland Cancers

Recurrent Salivary Gland Cancer | Recurrent Adenoid Cystic Carcinoma of the Oral Cavity | High-grade Salivary Gland Carcinoma | High-grade Salivary Gland Mucoepidermoid Carcinoma | Low-grade Salivary Gland Carcinoma | Low-grade Salivary Gland Mucoepidermoid Carcinoma | Salivary Gland Acinic Cell... and other conditions

Canada
Eisai Inc.

Completed

Phase II Study of ONTAK in Previously Treated Patients With Low-grade Non-Hodgkin's Lymphoma (NHL)

Non-Hodgkin's Lymphoma | Lymphoma, B-cell | Lymphoma, Low-grade

United States
Joshua Brody
Celldex Therapeutics

Completed

In Situ Vaccine for Low-Grade Lymphoma: Combination of Intratumoral Flt3L and Poly-ICLC With Low-Dose Radiotherapy

Low-Grade B-cell Lymphoma

United States
Marjukka Kolehmainen
VTT Technical Research Centre, Finland

Completed

The Health Effect of Diet Rich in Nordic Berries (Berry)

Metabolic Syndrome | Dyslipidemia | Impaired Glucose Tolerance | Low-grade Inflammation

Finland
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Mayo Clinic
National Cancer Institute (NCI)

Completed

Rituximab With or Without Yttrium Y-90 Ibritumomab Tiuxetan in Treating Patients With Untreated Follicular Lymphoma

Ann Arbor Stage I Grade 1 Follicular Lymphoma | Ann Arbor Stage I Grade 2 Follicular Lymphoma | Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann... and other conditions

United States
Genexine, Inc.

No longer available

Individual Patient Compassionate Use of GX-I7

Melanoma | Glioblastoma | High Grade Glioma | Recurrent Glioblastoma | Advanced Cancer

Korea, Republic of
National Cancer Institute (NCI)

Completed

Lenalidomide and Radiation Therapy in High Grade Gliomas or Diffuse Intrinsic Pontine Gliomas

High Grade Glioma | Anaplastic Astrocytoma | Diffuse Intrinsic Pontine Glioma

United States
National Cancer Institute (NCI)
Celgene Corporation

Active, not recruiting

Rituximab, Lenalidomide, and Ibrutinib in Treating Patients With Previously Untreated Stage II-IV Follicular Lymphoma

Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann Arbor Stage II Grade 3 Contiguous Follicular Lymphoma | Ann Arbor Stage II Grade 3 Non-Contiguous... and other conditions

United States
Katy Peters, MD, PhD
Servier

Not yet recruiting

ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas (ViCToRy)

Low Grade Glioma of Brain

United States
National Cancer Institute (NCI)

Active, not recruiting

Ofatumumab and Bendamustine Hydrochloride With or Without Bortezomib in Treating Patients With Untreated Follicular Non-Hodgkin Lymphoma

Grade 3a Follicular Lymphoma | Ann Arbor Stage III Grade 1 Follicular Lymphoma | Ann Arbor Stage III Grade 2 Follicular Lymphoma | Ann Arbor Stage IV Grade 1 Follicular Lymphoma | Ann Arbor Stage IV Grade 2 Follicular Lymphoma | Ann Arbor Stage III Grade 3 Follicular Lymphoma | Ann Arbor Stage...

United States
University of Maryland, Baltimore

Terminated

Phase II Trial of Low-Dose Whole Brain Radiotherapy With Concurrent Temozolomide and Adjuvant Temozolomide in Patients With Newly-Diagnosed Glioblastoma Multiforme (GCC 1224)

Histologically Proven Diagnosis of Glioblastoma or Gliosarcoma (WHO Grade IV)

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Refractory Grade 1 Follicular Lymphoma | Refractory Grade 2 Follicular Lymphoma | Refractory Grade 3a Follicular Lymphoma

United States
Zonguldak Bulent Ecevit University

Completed

Effects of Different Flow Anesthesia on Atelectasis

General Anesthesia | Atelectasis; Due to Anesthesia | Low- Flow Anesthesia | Minimal Flow Anesthesia

Turkey
National Cancer Institute (NCI)

Terminated

Positron Emission Tomography Using Fluorine F 18 EF5 to Find Oxygen in Tumor Cells of Patients Who Are Undergoing Surgery or Biopsy for Newly Diagnosed Brain Tumors

Adult Anaplastic Astrocytoma | Adult Anaplastic Ependymoma | Adult Anaplastic Oligodendroglioma | Adult Diffuse Astrocytoma | Adult Ependymoma | Adult Giant Cell Glioblastoma | Adult Glioblastoma | Adult Gliosarcoma | Adult Mixed Glioma | Adult Myxopapillary Ependymoma | Adult Oligodendroglioma | Adult Pilocytic... and other conditions

United States
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; M.D. Anderson Cancer Center; University of Colorado... and other collaborators

Completed

External Beam Radiation Therapy and Cetuximab Followed by Irinotecan and Cetuximab for Children and Young Adults With Newly Diagnosed Diffuse Pontine Tumors and High-Grade Astrocytomas

Brain Cancer

United States, Canada
Reid Merryman, MD
AbbVie; Genmab

Recruiting

Epcoritamab and Rituximab for First-line Follicular Lymphoma

Follicular Lymphoma | Low Grade Non-Hodgkin's Lymphoma, Adult

United States
Immune Design
Merck Sharp & Dohme LLC

Terminated

Study of Intratumoral G100 With Or Without Pembrolizumab or Rituximab In Participants With Follicular Non-Hodgkin's Lymphoma (MK-3475-174/IMDZ-G142)

Follicular Low Grade Non-Hodgkin's Lymphoma
University of Texas Southwestern Medical Center

Terminated

Study Of Two Non-Myeloablative Stem Cell Transplant Strategies For Low-Grade Lymphoma And CLL

Lymphoma | Leukemia

United States, Canada
National Cancer Institute (NCI)

Recruiting

A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Seromucinous Carcinoma | Ovarian Undifferentiated Carcinoma | Fallopian Tube Transitional Cell Carcinoma | Primary Peritoneal High Grade Serous Adenocarcinoma | Fallopian Tube Clear... and other conditions

United States

Clinical Trials on Low Grade Astrocytomas

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