Clinical Trials on Lung Diseases, Obstructive in Czechia

Total 5486 results

University of South Bohemia

Completed

Respirator and Breathing Compartments (Breathing)

Respiratory Complication | Face Mask Squeeze

Czechia
Medtronic Bakken Research Center

Completed

Engager Direct Aortic Clinical Study

Aortic Valve Stenosis

United Kingdom, Germany, Czechia
Brno University Hospital
Masaryk University; Institute of Biostatistics and Analyses, Masaryk University... and other collaborators

Not yet recruiting

Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19 (OBAAMA-COV)

Obstetric Anesthesia Care

Czechia
University Hospital, Motol

Terminated

Point-of-care Management of Coagulopathy in Lung Transplantation

Lung Transplantation

Czechia
Philip Morris Products S.A.

Recruiting

Effect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects With Chronic Bronchitis Symptoms.

Smoking | Tobacco Use | COPD

United States, Bulgaria, Czechia, Germany, Japan, Romania, Slovakia, United Kingdom
Brno University Hospital
European Society of Intensive Care Medicine; European Society of Anaesthesiology...

Completed

Corticosteroids in Severe COVID-19 (ASAP-ESICM/ESAIC Study) (ASAPESICMESAIC)

Severe COVID-19

Czechia
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

Inhaled Tacrolimus, Add-on to Inhaled Corticosteroids & Long Acting B2 Agonists in Moderate to Severe Persistent Asthma

Asthma, Bronchial | Bronchial Asthma

Russian Federation, Poland, Germany, Ukraine, Czech Republic
GlaxoSmithKline

Completed

Immunogenicity and Safety Study of a GSK Influenza Vaccine Candidate in Adults.

Influenza

Czechia
Brno University Hospital
Masaryk University

Withdrawn

Mouth-to-mouth Ventilation Efficiency Through Breathable Self-sterilizing Respirator During BLS in COVID-19 Pandemic (MOVE) (MOVE)

Basic Life Support Ventilation

Czechia
Novartis Pharmaceuticals

Completed

Study to Compare QVM149 and Free Triple Combination of Salmeterol/Fluticasone + Tiotropium (ARGON)

Asthma

Germany, India, Israel, Poland, Argentina, Russian Federation, Greece, Serbia, Turkey, Hungary, Mexico, Peru, Slovakia, Czechia, South Africa, Taiwan, Vietnam, Spain, Colombia, Chile
The Faculty Hospital Na Bulovce

Completed

Antibiotic Prophylaxis in the Prevention of Surgical Site Infections After Selected Urgent Abdominal Surgical Procedures

Small Bowel Obstruction | Acute Appendicitis | Perforated Gastroduodenal Ulcer

Czech Republic
Revent Medical International B.V.
Revent Medical, Inc.

Terminated

REV 002 Observational Study of the ReVENT Sleep Apnea System: Minimally Invasive Treatment for Obstructive Sleep Apnea

Obstructive Sleep Apnea

Germany, Belgium, Netherlands, Czech Republic, Switzerland
Bayer

Completed

Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic Bronchitis

Chronic Bronchitis

Spain, China, Argentina, Germany, Greece, Portugal, Canada, Netherlands, Australia, Peru, Philippines, Belgium, Switzerland, Chile, Italy, Thailand, Mexico, Lithuania, South Africa, Croatia, France, Colombia, Indonesia, Latvia, Hong Kong, United Kingdom and more
Glenmark Pharmaceuticals Ltd. India
Glenmark Pharmaceuticals S.A.

Completed

A Clinical Trial to Study the Effects of Revamilast in Patients With Chronic Persistent Asthma

Asthma

Poland, Czech Republic, India, Russian Federation, United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.

Terminated

A Study to Test if TEV-48574 is Effective in Relieving Asthma

Asthma

United States, Bulgaria, Czechia, Germany, Poland
CSL Behring

Completed

Extension Study of Zemaira® i.v. Administration in Subjects With Emphysema Due to alpha1-proteinase Inhibitor Deficiency.

Emphysema | Alpha 1-proteinase Inhibitor Deficiency

Australia, Canada, Czech Republic, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden
MedImmune LLC
Amgen

Completed

Study to Evaluate the Efficacy and Safety of MEDI9929 (AMG 157) in Adult Subjects With Inadequately Controlled, Severe Asthma

Asthma

United States, Slovakia, Israel, South Africa, Ukraine, Japan, Czechia, Hungary, Bulgaria, Serbia, Latvia, Lithuania
Novartis Pharmaceuticals
Schering-Plough

Completed

A Dose Ranging Trial of 4 Doses of Indacaterol Delivered Via TWISTHALER® Device in Adult and Adolescent Patients With Persistent Asthma

Asthma

Russian Federation, United Kingdom, Germany, Spain, Czech Republic, Israel, Poland, South Africa, Belgium, Hungary
CSL Behring

Completed

Zemaira in Subjects With Emphysema Due to Alpha1-Proteinase Inhibitor Deficiency

Emphysema | Alpha1-proteinase Inhibitor Deficiency

Australia, Russian Federation, United States, Denmark, Estonia, Finland, Germany, Ireland, Poland, Romania, Sweden, Canada, Czech Republic
Rhizen Pharmaceuticals SA

Completed

Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, in Patients With Solid Tumors

Solid Tumor | Metastatic Breast Cancer | Locally Advanced Breast Cancer | Extensive-stage Small-cell Lung Cancer | Platinum-Sensitive Fallopian Tube Carcinoma | Platinum-sensitive Ovarian Cancer | Platinum-Sensitive Peritoneal Cancer

Czechia, Poland
Ruth Tachezy, PhD.
Na Homolce Hospital; Medical Healthcom Prague

Completed

Effect of Vaccination in Patients With Recurrent Respiratory Papillomatosis

Squamous Papilloma of the Larynx

Czechia
Bond Avillion 2 Development LP

Completed

A Study to Assess the Efficacy and Safety of Budesonide/Albuterol Metered Dose Inhaler (BDA MDI/PT027) Used 4 Times Daily in Adults and Children 4 Years of Age or Older With Asthma (DENALI)

Asthma

United States, Germany, Ukraine, Serbia, Czechia, Argentina, Slovakia
AstraZeneca
Amgen

Recruiting

Tezepelumab Efficacy and Safety in Reducing Oral Corticosteroid Use in Adults With Oral Corticosteroid Dependent Asthma (SUNRISE)

Asthma

United States, Canada, Czechia, Korea, Republic of, India, Mexico, Turkey, Chile, Brazil, Thailand, Colombia, Poland, Peru, Malaysia, Philippines
Novartis Pharmaceuticals

Completed

Study of Efficacy and Safety of QAW039 in Patients With Severe Asthma Inadequately Controlled With Standard of Care Asthma Treatment.

Asthma

United States, India, Spain, Italy, Israel, Netherlands, Russian Federation, Lebanon, South Africa, Czechia, Greece, Serbia, Argentina, Mexico, Slovakia, Canada, Taiwan, Malaysia, Japan
Novartis Pharmaceuticals

Terminated

Study of Efficacy and Safety of CSJ117 in Patients With Severe Uncontrolled Asthma

Asthma

Germany, United States, Belgium, Poland, Latvia, Argentina, Guatemala, Philippines, Slovakia, Czechia, Hungary, Russian Federation, Japan, Bulgaria, Canada
Abbott

Completed

Evaluation of Effectiveness of the Treatment After Repeated Administration of Klacid®SR

Bronchitis | Chronic Bronchitis | Tracheobronchitis | Community-Acquired Pneumonia (CAP) | Tracheitis

Czech Republic
AstraZeneca
Pfizer

Completed

Efficacy and Safety of Oral Roflumilast Taken With Low Dose Inhaled Corticosteroids in Patients With Asthma (12 to 70 y) (BY217/M2-013)

Asthma

United States, Austria, Croatia, Czech Republic, Finland, France, Greece, Hungary, India, Ireland, Italy, New Zealand, Norway, Pakistan, Philippines, Poland, Portugal, Russian Federation, Singapore, South Africa, Spain, Taiwan, Thai... and more
GlaxoSmithKline
Iqvia Pty Ltd

Recruiting

An Open-Label Extension Study of GSK3511294 (Depemokimab) in Participants Who Were Previously Enrolled in 206713 (NCT04719832) or 213744 (NCT04718103) (AGILE)

Asthma

United States, Australia, Canada, France, Germany, Italy, Japan, Poland, Spain, China, Czechia, Hungary, Taiwan, United Kingdom
GlaxoSmithKline
Iqvia Pty Ltd

Completed

Placebo-controlled Efficacy and Safety Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype (SWIFT-1)

Asthma

United States, France, Germany, Poland, Spain, Italy, United Kingdom, China, Canada, Czechia, Russian Federation, Ireland
Centocor, Inc.
Centocor BV

Completed

A Study of Safety and Efficacy of CNTO 148 in Patients With Severe Persistent Asthma

Asthma

United Kingdom, United States, Germany, France, Poland, Bulgaria, Belgium, Czech Republic, Hungary, Netherlands, Sweden
University Hospital Ostrava

Completed

Monitoring Anticoagulation in Patients on ECMO for Severe Lung Failure

COVID-19 | ARDS

Czechia
Aspire Medical

Completed

Tongue Advancement for Obstructive Sleep Apnea

Sleep Apnea, Obstructive

Belgium, Czech Republic, Germany
Hoffmann-La Roche

Completed

A Study to Assess the Efficacy and Safety of MSTT1041A in Participants With Uncontrolled Severe Asthma

Asthma

Korea, Republic of, United States, Belgium, Czechia, Germany, Peru, Bulgaria, Russian Federation, Argentina, Ukraine, Canada, Poland, South Africa, New Zealand, Romania
AstraZeneca

Recruiting

A 12-week Study to Assess the Efficacy and Safety of Budesonide and Formoterol Fumarate Metered Dose Inhaler Relative to Budesonide Metered Dose Inhaler in Participants With Inadequately Controlled Asthma (LITHOS) (LITHOS)

Asthma

United States, Canada, South Africa, Korea, Republic of, Philippines, Czechia, Malaysia, Germany
GlaxoSmithKline
Iqvia Pty Ltd

Active, not recruiting

A Study of GSK3511294 (Depemokimab) in Participants With Severe Asthma With an Eosinophilic Phenotype (SWIFT-2)

Asthma

United States, Japan, Poland, Spain, Italy, Australia, Taiwan, France, Hungary, Canada, Czechia
Pulmagen Therapeutics

Completed

A Study to Evaluate Efficacy and Safety of ADC3680 in Subjects With Inadequately-Controlled Asthma

Asthma

United States, Croatia, Czechia, Germany, Hungary, Poland
Astellas Pharma Inc
Astellas Pharma Europe B.V.

Completed

Dose Response of Inhaled Tacrolimus in Patients With Moderate Persistent Asthma

Asthma, Bronchial | Bronchial Asthma

Russian Federation, Hungary, Germany, Poland, Bulgaria, Ukraine, Czech Republic
University Hospital Ostrava
University of Ostrava

Recruiting

BIA Assessment of Polymyoneuropathy in Critically Ill Patients

Sepsis | Respiratory Insufficiency | Trauma | Surgery

Czechia
AstraZeneca

Completed

STYLE - Symbicort Single Inhaler Therapy vs Conventional Therapy in Treatment of Persistent Asthma

Asthma

Croatia, Czech Republic, Latvia, Lithuania, Portugal, Slovakia, Greece, Iceland, Slovenia, Chile
Pearl Therapeutics, Inc.

Completed

Study to Assess Efficacy and Safety of PT009 Compared to PT005, PT008, and Symbicort® Turbuhaler® on Lung Function Over 24-Weeks in Subjects With Moderate to Very Severe COPD (telos)

Chronic Obstructive Pulmonary Disorder

United States, Canada, Germany, Hungary, Korea, Republic of, Poland, Russian Federation, Czechia
University Hospital Ostrava

Completed

Extraesophageal Reflux - Feasibility of Measurement of Pepsin in Saliva as a Diagnostic Option

Extraesophageal Reflux

Czechia
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Efficacy and Safety Evaluation of Budesonide/Formoterol SPIROMAX® Inhalation Powder Versus SYMBICORT® TURBOHALER®

Asthma

Austria, Belgium, Czechia, Denmark, Finland, France, Germany, Hungary, Israel, Italy, Netherlands, Poland, Russian Federation, Spain, Sweden, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of QGE031versus Placebo and Omalizumab in Patients Aged 18-75 Years With Asthma

Asthma

Germany, United States, India, Korea, Republic of, Poland, Romania, South Africa, France, Hungary, United Kingdom, Israel, Russian Federation, Turkey, Italy, Argentina, Mexico, Canada, Czechia, Finland, Portugal, Slovakia, Singapore, Guatema... and more
University Hospital Ostrava

Completed

The Influence of Blood Pressure Upon the Clarity of Surgical Field in Endonasal Surgery

Chronic Rhinosinusitis (Diagnosis)

Czechia
AstraZeneca

Completed

Symbicort Rapihaler Therapeutic Equivalence Study (ESTHER)

Bronchial Asthma

Bulgaria, Czech Republic, Poland, Hungary
AstraZeneca

Completed

Utilization of Fixed Combination (Budesonide/Formoterol and Salmeterol/Fluticasone and Beclomethasone/Formoterol) in Treatment of Asthma Patients (UFO)

Asthma

Czech Republic
GlaxoSmithKline

Completed

A Study to Assess the Effects of Fluticasone Furoate and GW642444M Combination in Healthy Subjects and in Subjects With Mild, Moderate or Severe Hepatic Impairment.

Asthma

Czechia, Slovakia
GlaxoSmithKline

Terminated

Study to Evaluate the Safety and Immunogenicity of GSK Biological Pandemic Candidate Influenza Vaccine (H1N1) in Children

Influenza

Czechia
GlaxoSmithKline

Completed

A Study to Determine Long-term Safety of Mepolizumab in Asthmatic Subjects

Asthma

United States, Argentina, Australia, Canada, France, Germany, Japan, Netherlands, Poland, Russian Federation, Spain, Ukraine, Belgium, Chile, Korea, Republic of, United Kingdom, Czechia, Mexico, Italy
Rostrum Medical Innovations Inc.
Medical Initiatives

Not yet recruiting

Evaluation of VQm PHM on Pulmonary Health Parameters for ICU

Stroke | Pneumonia | COPD | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Ventilators, Mechanical

France, United States, Austria, Czechia

Clinical Trials on Lung Diseases, Obstructive in Czechia

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