Clinical Trials on Lung Neoplasm

Total 149285 results

Sun Yat-sen University

Unknown

Sintilimab Combined With Bevacizumab for Brain Metastases From Non-small Cell Lung Cancer

Non Small Cell Lung Cancer | Bevacizumab | Brain Metastases | Sintilimab

China
AbbVie (prior sponsor, Abbott)

Completed

Comparison of Veliparib and Whole Brain Radiation Therapy (WBRT) Versus Placebo and WBRT in Adults With Brain Metastases From Non-Small Cell Lung Cancer

Brain Metastases From Non-small Cell Lung Cancer
Sanofi

Terminated

Investigate the Maximum Tolerated Dose of Vandetanib and Concurrent Whole Brain Radiotherapy (WBRT) in Patients With Non-small Cell Lung Cancer (NSCLC) and Brain Metastases

Non-small Cell Lung Cancer (NSCLC)

Netherlands
AstraZeneca

Terminated

Iressa in the Treatment of Brain Metastases From Non Small Cell Lung Cancer

Brain Neoplasms | Non Small Cell Lung Cancer

Italy
University Health Network, Toronto
Hoffmann-La Roche

Recruiting

An Exploratory Study of Atezolizumab and Bevacizumab in Hepatocellular Carcinoma and Non-Small Cell Lung Cancer With Liver Metastases (INTEGRATE)

Hepatocellular Carcinoma | Liver Metastases | Non-small Cell Lung Cancer Metastatic

Canada
Novartis Pharmaceuticals

Completed

Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Brain Metastasis

United States
Assistance Publique - Hôpitaux de Paris
Ministry of Health, France

Terminated

Assess the Efficacy of Whole Brain Radiation Therapy in Lung Cancer Patients With Brain Metastasis (ARPEGE)

Brain Metastasis | EGFR-mutated Lung Adenocarcinoma

France
Roswell Park Cancer Institute

Completed

Cisplatin in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer or Lung Metastasis

Stage IIIB Non-Small Cell Lung Cancer | Stage IV Non-Small Cell Lung Cancer | Stage IV Adult Soft Tissue Sarcoma | Metastatic Malignant Neoplasm in the Lung

United States
Jonsson Comprehensive Cancer Center
Tesaro, Inc.; Translational Research in Oncology-U.S

Recruiting

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma | Stage IIIC Lung Cancer AJCC v8

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

Small Cell Lung Carcinoma | Lung Cancer | Lung Cancer Metastatic | Small-cell Lung Cancer | Brain Metastases | Brain Metastases, Adult

United States
University Hospital Tuebingen

Completed

Preoperative Percutaneous Radiofrequency Ablation of Primary and Secondary Lung Tumors

Lung Cancer | Lung Metastasis

Germany
Xiangya Hospital of Central South University
Wu Jieping Medical Foundation

Recruiting

Radiotherapy Combined With PD-1 Inhibitors and Chemotherapy in the Treatment of NSCLC Patients With Symptomatic Brain Metastases

Non-small Cell Lung Cancer Metastatic | Brain Metastases

China
Guangzhou Medical University

Unknown

Temozolomide in Preventing Brain Metastases in Small Cell Lung Cancer

Small Cell Lung Cancer | Metastatic Carcinoma

China
Third Military Medical University

Unknown

Application of Detecting Circulating Tumor Cells in the Accurate Treatment of Early Stage Lung Adenocarcinoma (CTCs detection)

Treatment | Diagnoses Diseases | Lung Adenocarcinoma, Stage I | Circulating Tumor Cells

China
Stanford University
National Comprehensive Cancer Network

Completed

Phase I Vorinostat Concurrent With Stereotactic Radiosurgery (SRS) in Brain Metastases From Non-Small Cell Lung Cancer

Carcinoma, Non-Small-Cell Lung | Neoplasm Metastasis | Lung Cancer | Brain Cancer

United States
Albert Einstein College of Medicine
National Cancer Institute (NCI)

Completed

PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancer (PAINT)

Stage IIIA Non-Small Cell Lung Cancer | Stage IIIB Non-Small Cell Lung Cancer | Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer | Metastatic Malignant Neoplasm in the Brain | Stage IIA Non-Small Cell Lung Carcinoma | Stage IIB Non-Small Cell Lung Carcinoma

United States
Groupe Français de Pneumo-Cancérologie
Bristol-Myers Squibb

Active, not recruiting

Observational Study in Patients With Previously Unresectable Malignant Pleural Mesothelioma Treated With Nivolumab and Ipilimumab (MESO-IMMUNE) (MESO-IMMUNE)

Malignant Pleural Mesothelioma | Unresectable Malignant Neoplasm

France
Memorial Sloan Kettering Cancer Center

Completed

Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung Metastases

Synovial Sarcoma | Single or Multiple Lung Metastases

United States
Daping Hospital and the Research Institute of Surgery...

Unknown

Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Bone Metastasis
Yi-Long Wu

Terminated

Prophylactic Cranial Irradiation (PCI) Versus no PCI in Non Small Cell Lung Cancer After a Response to Chemotherapy (PCI)

Brain Metastases

China
Centre Hospitalier Universitaire de Nice

Completed

Multicenter Validation of the Sensitivity of Theranostic ALK Rearrangement Detection by FISH Analysis and Prevalence of Escaping Mutations in Circulating Tumor Cells for the Non-invasive Management of Lung Cancer Patients (STALKLUNG01)

Lung Neoplasms

France
University of Milan

Completed

Combined Liver and Right Lung Resection for Colorectal Metastases by Means of J-shaped Thoracophrenolaparotomy

Multiple Pulmonary Nodules | Colon Cancer Liver Metastasis

Italy
Guangzhou Medical University

Not yet recruiting

Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib.

Leptomeningeal Metastasis
Cadex Genomics

Completed

Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Non-Small Cell Lung Carcinoma

United States, Canada
Joshua Palmer
Genentech, Inc.

Recruiting

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements (DURABLE)

NSCLC | Lung Cancer | Brain Metastases

United States
University of Colorado, Denver
National Cancer Institute (NCI)

Terminated

Brigatinib Before Brain Irradiation Trial (B3i Trial)

Lung Cancer | Brain Metastases

United States
Shanghai Chest Hospital

Unknown

Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases) (EGFR)

Non-Small Cell Lung Cancer | Brain Metastases | EGFR Gene Mutation

China
Guangdong Provincial People's Hospital

Unknown

Efficacy of Gefitinib for Brain Metastasis of Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | Brain Metastasis
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States, Canada
Angiochem Inc

Terminated

GRN1005 in Non-Small Cell Lung Cancer (NSCLC) Patients With Brain Metastases (GRABM-L) (GRABM-L)

Non-small Cell Lung Cancer (NSCLC) With Brain Metastases

United States, Canada
Wuhan Union Hospital, China

Unknown

Study of EGFR-TKI to Asymptomatic Brain Metastases of NSCLC (EABM)

Asymptomatic Brain Metastases of Non Small Cell Lung Cancer
Dana-Farber Cancer Institute

Active, not recruiting

Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases

Small Cell Lung Cancer | Brain Metastases

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Terminated

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States, Canada
M.D. Anderson Cancer Center

Suspended

Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Stereotactic Body Radiation Therapy With Immunotherapy for the Treatment of Mesothelioma

Pleural Mesothelial Neoplasm

United States
Ruijin Hospital

Active, not recruiting

Circulating Exosome RNA in Lung Metastases of Primary High-Grade Osteosarcoma

Osteosarcoma | Lung Metastases

China
NeuroVita Clinic
Blokhin's Russian Cancer Research Center; Russian Foundation of Technological... and other collaborators

Unknown

Proteome-based Immunotherapy of Lung Cancer Brain Metastases

Neoplasm Metastasis

Russian Federation
Liza Villaruz, MD
Exelixis

Terminated

Trial of Cabozantinib (XL184) in Non-Small Cell Lung Cancer With Brain Metastases

Non Small Cell Lung Cancer (NSCLC) | Metastases to the Brain

United States
Taizhou Hospital

Not yet recruiting

High-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain Metastases

Lung Cancer, Nonsmall Cell
Fudan University
Betta Pharmaceuticals Co., Ltd.

Unknown

X-396(Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases

Nonsmall Cell Lung Cancer | Brain Metastases
Cliniques universitaires Saint-Luc- Université...

Completed

Mechanically-assisted Ventilation in the Treatment of Moving Tumours With Photon and Proton Therapies

Liver Cancer | Ventilator Lung | Radiotherapy; Complications | Thoracic Neoplasm

Belgium
Hospices Civils de Lyon

Unknown

Association of Bone and Metabolic Parameters With Overall Survival in Patients With Bone Metastases From Adenocarcinoma Lung Cancer (POUMOS) (POUMOS)

Lung Cancer | Bone Metastases

France
NovoCure GmbH

Active, not recruiting

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

Brain Metastases From Non-small Cell Lung Cancer (NSCLC)

United States, China, Israel, Spain, Austria, Canada, Hong Kong, Germany, France, Bulgaria, Croatia, Hungary, Italy, Poland, Serbia
NovoCure Ltd.

Unknown

Effect of TTFields (150kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-5 Brain Metastases Following Optimal Standard Local Treatment (COMET)

1-5 Brain Metastases From Non-Small Cell Lung Cancer

Poland, Czech Republic, Italy, France, Spain
Medical University of Vienna
University of Copenhagen; University of Leipzig; Careggi Hospital

Recruiting

Predicting Lung Cancer-Associated Cachexia With PET Imaging (LUCAPET)

Cachexia | Lung Neoplasm

Austria, Germany, Italy
Centre Hospitalier Intercommunal Creteil
Groupe Français de Pneumo-Cancérologie

Terminated

Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases (METAL2)

Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Cerebral Metastases | Adenocarcinoma of Lung Metastatic to Brain

France
Merck Sharp & Dohme LLC

Completed

Temozolomide for Treatment of Brain Metastases From Non-Small Cell Lung Cancer (Study P03247)

Carcinoma, Non-Small-Cell Lung | Neoplasm Metastasis | Brain Neoplasms
RenJi Hospital

Recruiting

Stereotactic Body Radiation Therapy for Spinal Metastases in Favorite Tumors

Breast Cancer | Prostate Cancer | Non Small Cell Lung Cancer

China
Betta Pharmaceuticals Co., Ltd.
Fudan University

Unknown

X-396 (Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases

Brain Metastases | Lung Cancer, Nonsmall Cell

China
Eli Lilly and Company

Terminated

A Study of LY2584702 With Erlotinib or Everolimus in Participants With Solid Tumors

Renal Cell Carcinoma | Metastases, Neoplasm | Neuroendocrine Tumors | Carcinoma, Non-small Cell Lung

France, United States

Clinical Trials on Lung Neoplasm

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