Clinical Trials on Lung Neoplasms

Total 148654 results

M.D. Anderson Cancer Center

Active, not recruiting

Stereotactic Body Radiation Therapy With or Without Nivolumab in Treating Patients With Stage I-IIA or Recurrent Non-small Cell Lung Cancer

Lung Non-Small Cell Squamous Carcinoma | Stage IIA Lung Cancer AJCC v8 | Neuroendocrine Carcinoma | Lung Atypical Carcinoid Tumor | Minimally Invasive Lung Adenocarcinoma | Lung Neuroendocrine Neoplasm | Stage I Lung Cancer AJCC v8 | Stage IA1 Lung Cancer AJCC v8 | Stage IA2 Lung Cancer AJCC v8 | Stage... and other conditions

United States
Shanghai Chest Hospital

Unknown

Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases) (EGFR)

Non-Small Cell Lung Cancer | Brain Metastases | EGFR Gene Mutation

China
Guangdong Provincial People's Hospital

Unknown

Efficacy of Gefitinib for Brain Metastasis of Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer | Brain Metastasis
Daping Hospital and the Research Institute of Surgery...

Recruiting

Effect of Muscle and Skin Fixation of Thoracic Drainage Tube on Postoperative Pain

Lung Neoplasms | Postoperative Pain | Lung Cancer | Thoracoscopic Surgery | Pulmonary Neoplasm

China
Daping Hospital and the Research Institute of Surgery...

Unknown

Zoledronic Acid Combined Radiotherapy for Bone Metastasis of Non-small Cell Lung Cancer

Non-small Cell Lung Cancer | Bone Metastasis
Jonsson Comprehensive Cancer Center
Tesaro, Inc.; Translational Research in Oncology-U.S

Recruiting

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma | Stage IIIC Lung Cancer AJCC v8

United States
Xiangya Hospital of Central South University
Wu Jieping Medical Foundation

Recruiting

Radiotherapy Combined With PD-1 Inhibitors and Chemotherapy in the Treatment of NSCLC Patients With Symptomatic Brain Metastases

Non-small Cell Lung Cancer Metastatic | Brain Metastases

China
Guangzhou Medical University

Unknown

Temozolomide in Preventing Brain Metastases in Small Cell Lung Cancer

Small Cell Lung Cancer | Metastatic Carcinoma

China
Sun Yat-sen University
Novartis

Completed

Screening Non Small Cell Lung Cancer With Bone Metastasis and Efficacy and Safety Research of Receiving Bisphosphonates (BLEST)

Bone Metastases | Non-small Cell Lung Cancer

China
Joshua Palmer
Genentech, Inc.

Recruiting

Delayed or Upfront Brain RAdiotherapy in Treatment naïve Lung Cancer Patients With Asymptomatic or Minimally Symptomatic Brain Metastases and ALK rEarrangements (DURABLE)

NSCLC | Lung Cancer | Brain Metastases

United States
University of Colorado, Denver
National Cancer Institute (NCI)

Terminated

Brigatinib Before Brain Irradiation Trial (B3i Trial)

Lung Cancer | Brain Metastases

United States
National Cancer Institute (NCI)
Radiation Therapy Oncology Group

Terminated

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | Metastatic Malignant Neoplasm in the Brain | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States, Canada
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma

Malignant Solid Neoplasm | Melanoma | Colitis | Lung Non-Small Cell Carcinoma | Malignant Genitourinary System Neoplasm

United States
Cadex Genomics

Completed

Development of a Cell Free DNA Assay as a Biomarker for Predicting Early Non-response to Therapy in Metastatic Cancer

Metastatic Colorectal Cancer | Metastatic Breast Cancer | Metastatic Non-Small Cell Lung Carcinoma

United States, Canada
Yi-Long Wu

Terminated

Prophylactic Cranial Irradiation (PCI) Versus no PCI in Non Small Cell Lung Cancer After a Response to Chemotherapy (PCI)

Brain Metastases

China
Hoffmann-La Roche

Completed

Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors (ARROW)

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Endocrine System Diseases | Gastrointestinal Neoplasms | Neoplasms, Germ Cell and Embryonal | Head and Neck Neoplasms | Carcinoma, Non-Small-Cell Lung | Respiratory Tract... and other conditions

France, Spain, United States, Korea, Republic of, United Kingdom, Taiwan, China, Belgium, Singapore, Netherlands, Germany, Italy, Hong Kong
Centre Hospitalier Universitaire de Nice

Completed

Multicenter Validation of the Sensitivity of Theranostic ALK Rearrangement Detection by FISH Analysis and Prevalence of Escaping Mutations in Circulating Tumor Cells for the Non-invasive Management of Lung Cancer Patients (STALKLUNG01)

Lung Neoplasms

France
University of Milan

Completed

Combined Liver and Right Lung Resection for Colorectal Metastases by Means of J-shaped Thoracophrenolaparotomy

Multiple Pulmonary Nodules | Colon Cancer Liver Metastasis

Italy
Guangzhou Medical University

Not yet recruiting

Intrathecal Pemetrexed for Leptomeningeal Metastasis From Lung Adenocarcinoma That Progressed After Osimertinib.

Leptomeningeal Metastasis
Memorial Sloan Kettering Cancer Center

Completed

Whole Lung IMRT in Children and Adults With Synovial Sarcoma and Lung Metastases

Synovial Sarcoma | Single or Multiple Lung Metastases

United States
NovoCure GmbH

Active, not recruiting

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

Brain Metastases From Non-small Cell Lung Cancer (NSCLC)

United States, China, Israel, Spain, Austria, Canada, Hong Kong, Germany, France, Bulgaria, Croatia, Hungary, Italy, Poland, Serbia
NovoCure Ltd.

Unknown

Effect of TTFields (150kHz) in Non-small Cell Lung Cancer (NSCLC) Patients With 1-5 Brain Metastases Following Optimal Standard Local Treatment (COMET)

1-5 Brain Metastases From Non-Small Cell Lung Cancer

Poland, Czech Republic, Italy, France, Spain
Dana-Farber Cancer Institute

Active, not recruiting

Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases

Small Cell Lung Cancer | Brain Metastases

United States
Angiochem Inc

Terminated

GRN1005 in Non-Small Cell Lung Cancer (NSCLC) Patients With Brain Metastases (GRABM-L) (GRABM-L)

Non-small Cell Lung Cancer (NSCLC) With Brain Metastases

United States, Canada
Wuhan Union Hospital, China

Unknown

Study of EGFR-TKI to Asymptomatic Brain Metastases of NSCLC (EABM)

Asymptomatic Brain Metastases of Non Small Cell Lung Cancer
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Brain | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States, Canada
Liza Villaruz, MD
Exelixis

Terminated

Trial of Cabozantinib (XL184) in Non-Small Cell Lung Cancer With Brain Metastases

Non Small Cell Lung Cancer (NSCLC) | Metastases to the Brain

United States
Sanofi

Completed

A Study Assessing Efficacy and Safety of SAR125844 in NSCLC Patients With MET Amplification

Neoplasm Malignant

Belgium
Hospices Civils de Lyon

Unknown

Association of Bone and Metabolic Parameters With Overall Survival in Patients With Bone Metastases From Adenocarcinoma Lung Cancer (POUMOS) (POUMOS)

Lung Cancer | Bone Metastases

France
Centre Hospitalier Intercommunal Creteil
Groupe Français de Pneumo-Cancérologie

Terminated

Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases (METAL2)

Non-small Cell Lung Cancer | Non-small Cell Lung Cancer Metastatic | Cerebral Metastases | Adenocarcinoma of Lung Metastatic to Brain

France
Taizhou Hospital

Not yet recruiting

High-dose Furmonertinib Versus Osimertinib in Advanced EGFRm NSCLC Patients With Brain Metastases

Lung Cancer, Nonsmall Cell
Fudan University
Betta Pharmaceuticals Co., Ltd.

Unknown

X-396(Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases

Nonsmall Cell Lung Cancer | Brain Metastases
Ruijin Hospital

Active, not recruiting

Circulating Exosome RNA in Lung Metastases of Primary High-Grade Osteosarcoma

Osteosarcoma | Lung Metastases

China
NeuroVita Clinic
Blokhin's Russian Cancer Research Center; Russian Foundation of Technological... and other collaborators

Unknown

Proteome-based Immunotherapy of Lung Cancer Brain Metastases

Neoplasm Metastasis

Russian Federation
Betta Pharmaceuticals Co., Ltd.
Fudan University

Unknown

X-396 (Ensartinib) Capsules in ALK-Positive NSCLC Patients With Brain Metastases

Brain Metastases | Lung Cancer, Nonsmall Cell

China
Merck Sharp & Dohme LLC

Completed

Temozolomide for Treatment of Brain Metastases From Non-Small Cell Lung Cancer (Study P03247)

Carcinoma, Non-Small-Cell Lung | Neoplasm Metastasis | Brain Neoplasms
AHS Cancer Control Alberta
Cross Cancer Institute

Completed

Cone Beam CT Scanning in Lung and Bladder Cancer.

Bladder Carcinoma | Small Cell Carcinoma | Lung Neoplasm

Canada
Hadassah Medical Organization

Recruiting

A Study to Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone, in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases

NSCLC | Non-small Cell Lung Cancer | EGF-R Positive Non-Small Cell Lung Cancer | Brain Metastases | EGFR Gene Mutation

Israel
Fred Hutchinson Cancer Center
SignalOne Bio, Inc.

Terminated

Genetically Engineered Cells (MAGE-A1-specific T Cell Receptor-transduced Autologous T-cells) and Atezolizumab for the Treatment of Metastatic Triple Negative Breast Cancer, Urothelial Cancer, or Non-small Cell Lung Cancer

Metastatic Lung Non-Small Cell Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Solid Neoplasm | Metastatic Urothelial Carcinoma | Metastatic Triple-Negative Breast Carcinoma

United States
Sun Yat-sen University

Not yet recruiting

Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases (SUPER BRAIN)

Bevacizumab | Brain Metastases | Immunotherapy | Non-small Cell Lung Cancer Stage II

China
Second Affiliated Hospital of Nanchang University
Nanchang University

Unknown

The Role of Brain Radiotherapy in Patients With Asymptomatic Brain Metastasis in the Era of Targeted Therapy for NSCLC (BRATR)

Non Small Cell Lung Cancer | Brain Metastases

China
UNC Lineberger Comprehensive Cancer Center
Sivan Innovation Ltd.

Completed

Remote Monitoring of Lung Cancer Patient-Reported Outcomes Using Moovcare® (LC-PRO)

Lung Cancer | Neoplasms, Lung | Pulmonary Neoplasms | Neoplasms, Pulmonary | Pulmonary Cancer | Cancer of Lung

United States
Kadmon Corporation, LLC

Completed

Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal Metastases

Non-Small Cell Lung Cancer | Brain Metastases | Leptomeningeal Metastases

United States
Affiliated Hospital to Academy of Military Medical...

Unknown

Safety and Efficacy of DC-CIK in Patients With Advanced Non-Small-Cell Lung Cancer With Bone Metastases

Non-Small-Cell Lung Cancer With Bone Metastases

China
Sun Yat-sen University
Novartis

Completed

Efficacy and Safety Study of ZOMETA® in Treatment of High-level NTX Non Small Cell Lung Cancer With Bone Metastasis

Non Small Cell Lung Cancer | Bone Metastases | High NTX Level

China
RenJi Hospital

Recruiting

Stereotactic Body Radiation Therapy for Spinal Metastases in Favorite Tumors

Breast Cancer | Prostate Cancer | Non Small Cell Lung Cancer

China
Intergroupe Francophone de Cancerologie Thoracique

Active, not recruiting

Study of Osimertinib in Patients With a Lung Cancer With Brain or Leptomeningeal Metastases With EGFR Mutation (ORBITAL)

Non Small Cell Lung Cancer Metastatic | Brain Metastases | EGFR Activating Mutation | Leptomeningeal Metastasis

France
Baptist Health South Florida

Withdrawn

Study of LUNG Stereotactic Adaptive Ablative Radiotherapy (LUNG STAAR)

Lung Cancer | Lung Tumor

United States
Ohio State University Comprehensive Cancer Center

Completed

Embedded Palliative Care in Managing Symptoms in Participants With Recurrent Stage III-IV Thoracic Malignancies and Their Caregivers

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Recurrent Lung Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Caregiver | Metastatic Thymic Carcinoma | Malignant Pleural... and other conditions

United States
Oliver Jonas
Massachusetts General Hospital

Completed

Microdevice for Evaluating Drug Response in Site in Lung Lesions

Lung Cancer | Lung Tumor

United States

Clinical Trials on Lung Neoplasms

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