Clinical Trials on Lung in South Africa

Total 3605 results

Australian National University
St Vincent's Hospital Melbourne; The George Institute; Royal North Shore Hospital and other collaborators

Withdrawn

Inhaled Heparin for Hospitalised Patients With Coronavirus Disease 2019 (COVID-19) (INHALE-HEP)

COVID-19

Australia
Sorrento Therapeutics, Inc.

Completed

Study to Assess the Safety, Tolerability and Pharmacokinetics of STI-1558 in Healthy Volunteers

COVID-19

Australia
Boehringer Ingelheim

Completed

Actuation Indicator Trial in Patients With COPD

Pulmonary Disease, Chronic Obstructive

United States
Duke University
Eli Lilly and Company

Terminated

Adjuvant Cisplatin With Either Genomic-Guided Vinorelbine or Pemetrexed for Early Stage Non-Small-Cell Lung Cancer (TOP0703)

Carcinoma, Non-Small-Cell Lung

United States
Mylan Inc.
Theravance Biopharma

Completed

Revefenacin Peak Inspiratory Flow Rate (PIFR) Study in COPD

Chronic Obstructive Pulmonary Disease, COPD | Low Peak Inspiratory Flow Rate (PIFR)

United States
Hoffmann-La Roche

Completed

Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Healthy Pediatric Participants From Birth to < 1 Year With Influenza-Like Symptoms

Influenza

Poland, United States, Costa Rica, Bulgaria, South Africa, Spain, Israel, Finland, Russian Federation
National Cancer Institute (NCI)

Completed

Cabozantinib-S-Malate and Erlotinib Hydrochloride in Treating Patients With Previously Treated Metastatic Non-Small Cell Lung Cancer

Recurrent Non-Small Cell Lung Carcinoma | Stage IV Non-Small Cell Lung Cancer AJCC v7

United States
Novartis Pharmaceuticals

Completed

QVA Mechanistic Efficacy Study (Receptor Effects, Etc)

Chronic Obstructive Pulmonary Disease

United Kingdom
Larkin Community Hospital

Withdrawn

Phase 3 Open-Label Controlled Trial of Convalescent Plasma in Early COVID-19 Infection

Covid19

United States
Medical University of South Carolina

Completed

COVID Breath Test - Ancon

Covid19

United States
VA Office of Research and Development
Minneapolis Veterans Affairs Medical Center; Ralph H. Johnson VA Medical Center

Enrolling by invitation

Teachable Moment to Opt-out of Tobacco: Interactive Voice Response Quit Line for Veteran Active Smokers With Lung Nodules (TeaMOUT)

Tobacco Use | Multiple Pulmonary Nodules | Solitary Pulmonary Nodule

United States
Novexel Inc

Completed

Comparative Study of NXL103 Versus Comparator in Adults With Community Acquired Pneumonia

Community Acquired Pneumonia

Germany, Chile, Peru, Estonia, Croatia, South Africa, Poland, Romania, Ukraine
National Cancer Institute (NCI)

Completed

MK2206 and Erlotinib Hydrochloride in Treating Patients With Advanced Non-Small Cell Lung Cancer Who Have Progressed After Previous Response to Erlotinib Hydrochloride Therapy

Lung Adenocarcinoma | Recurrent Non-Small Cell Lung Carcinoma | Adenosquamous Lung Carcinoma | Bronchioloalveolar Carcinoma | Large Cell Lung Carcinoma | Squamous Cell Lung Carcinoma

United States
Larkin Community Hospital

Unknown

Measurement of IL-6 and Secondary Inflammatory Markers Before and After Therapeutic Plasma Exchange (TPE) in Hospitalized Patients

COVID-19

United States
Kirby Institute
ViiV Healthcare; University of Witwatersrand, South Africa; University of Liverpool and other collaborators

Completed

COHIVE: Coronavirus (COVID-19) Outcomes in HIV Evaluation in Resource Limited Settings

Coronavirus Infection | HIV-infection/Aids

Uganda, Cameroon, Argentina, Brazil, India, Malaysia, Nigeria, South Africa, Thailand, Zimbabwe
GlaxoSmithKline

Completed

Safety, Tolerability and Clinical Effect of Danirixin in Adults With Influenza

Virus Diseases

United States, South Africa, Australia
GlaxoSmithKline

Completed

The Purpose of the This Study is to Evaluate the Spirometric Effect (Trough FEV1) of Umeclidinium/Vilanterol 62.5/25 mcg Once Daily Compared With Tiotropium 18mcg Once Daily Over a a 12-week Treatment Period in Subjects With COPD Who Continue to Have Symptoms on Tiotropium

Pulmonary Disease, Chronic Obstructive

Argentina, Germany, Ukraine, United States, Estonia, South Africa, Sweden, Norway, Russian Federation, Korea, Republic of
Syndax Pharmaceuticals

Terminated

A Phase 2 Exploratory Study of Erlotinib and SNDX-275 in Participants With Non-small Cell Lung Carcinoma Who Are Progressing on Erlotinib

Non Small Cell Lung Cancer

United States
Worldwide Innovative Network Association
Pfizer; ARC Foundation for Cancer Research

Terminated

Survival Prolongation by Rationale Innovative Genomics (SPRING)

Non-small Cell Lung Cancer Metastatic | Non-small Cell Lung Cancer Stage IIIB

Israel, United States, Luxembourg, Spain
GlaxoSmithKline

Completed

A 12 Week Study To Assess Efficacy And Safety Of GW856553 In Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Russian Federation, Estonia, Netherlands, South Africa, Korea, Republic of, Slovenia, New Zealand, Finland, Latvia, Lithuania, United Kingdom
GlaxoSmithKline

Completed

A 4-week Dose-Ranging, Dose-Interval, Efficacy, Safety and Tolerability Study of GSK961081 in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive

Germany, Romania, Ukraine, Estonia, Russian Federation, South Africa, Sweden, Netherlands, Slovakia
Trans Tasman Radiation Oncology Group
Cancer Council Queensland; Victorian Cancer Council

Completed

Chemoradiotherapy in Patients With Localised Lung Cancer

Non Small Cell Lung Carcinoma

Australia
Atriva Therapeutics GmbH

Terminated

Clinical Trial to Evaluate the Safety and Efficacy of ATR-002 in Adult Hospitalized Patients With COVID-19 (RESPIRE)

COVID-19

Germany, India, Netherlands, Poland, Romania, South Africa, Spain
Vaxine Pty Ltd
Australian Respiratory and Sleep Medicine Institute Ltd

Not yet recruiting

Covid-19 and Influenza Oral Vaccine Study

Influenza, Human | covid19 Infection

Australia
GlaxoSmithKline

Completed

Pharmacokinetic and Pharmacodynamic (PK and PD) Study of Fluticasone Propionate and Salmeterol Combination Product Delivered in a Capsule-based Inhaler and in a Multi-dose Dry Powder Inhaler in Moderate Asthma Patients and Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD) Patients.

Asthma

Australia, New Zealand
The University of Queensland

Active, not recruiting

International Lung Screen Trial (ILST) (ILST)

Neoplasms | Respiratory Tract Diseases | Lung Diseases | Neoplasms by Site | Lung Neoplasms | Respiratory Tract Neoplasms | Thoracic Neoplasms | Non-small Cell Lung Cancer | Smokers at Risk of Lung Cancer

Australia, Canada
Western Sydney Local Health District
Bristol-Myers Squibb; University of Western Sydney

Recruiting

Risk Factors of Immune-ChEckpoint Inhibitors MEdiated Liver, Gastrointestinal, Endocrine and Skin Toxicity (ICEMELT)

Melanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Gastric Cancer | Mesothelioma | Endometrial Cancer | Lung Cancer, Nonsmall Cell

Australia
Medical University of South Carolina
National Cancer Institute (NCI)

Not yet recruiting

Intervention to Improve Utilization of Extended Venous Thromboembolism Prophylaxis After Cancer Surgery

Cancer | Surgery | Deep Vein Thrombosis | Venous Thromboembolism | Pulmonary Embolism

United States
Genzyme, a Sanofi Company

Completed

This Study is to Compare the Efficacy of ZD6474 and ZD1839 in Subjects With NSCLC.

Carcinoma, Non-Small-Cell Lung

United States, South Africa, United Kingdom, Germany, Argentina, Belgium
GlaxoSmithKline

Completed

Effects of a Orally Inhaled Fluticasone Furoate on Growth Velocity in Prepubertal, Paediatric Subjects With Asthma Over a Year

Asthma

Argentina, Russian Federation, United States, South Africa, Poland, Romania
Chiesi Farmaceutici S.p.A.
Chiesi USA, Inc.

Completed

Dose Finding Study of CHF 4226 for Treating Patients With COPD

Chronic Obstructive Pulmonary Disease

United States, Czech Republic, Germany, Poland, Romania, South Africa
Novartis

Completed

A Study to Investigate the Bronchodilatory Effect of NVA237 in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease

United States, Germany
GlaxoSmithKline

Completed

Comparing Two Respiratory Drugs When Used In Combination And Separately From A Novel Inhaler Device In Healthy Subjects

Asthma

Australia
Brno University Hospital
European Society of Intensive Care Medicine; European Society of Anaesthesiology...

Completed

Corticosteroids in Severe COVID-19 (ASAP-ESICM/ESAIC Study) (ASAPESICMESAIC)

Severe COVID-19

Czechia
Prisma Health-Upstate

Completed

COVID-19 on Placental Gene Expression and Pathology (PROSPER)

COVID-19 | SARS-CoV-2 Infection

United States
University of Athens
Hellenic Pasteur Institute

Completed

Influenza Vaccine Effectiveness of a Quadrivalent Vaccine in Pregnant Women and Young Infants, 2019-2020

Influenza in Human

Greece
Medical University of South Carolina
National Institutes of Health (NIH); National Institute of General Medical...

Completed

NeuroCovid Rehab and Recovery Related to COVID-19 Diagnosis

Covid19 | Coronavirus

United States
University of Athens
University of Thessaly

Completed

Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure (HFO-TGI-2)

Respiratory Distress Syndrome

Greece
Dey

Completed

Study to Evaluate the Safety of Long-Term Use of Perforomist® (Formoterol Fumarate)

COPD

United States
Pearl Therapeutics, Inc.

Withdrawn

Efficacy and Safety of Two Doses of Formoterol Fumarate MDI (PT005) in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), Compared to Foradil® Aerolizer® as an Active Control

COPD

United States
Trans Tasman Radiation Oncology Group

Unknown

Hypofractionated Radiotherapy (Stereotactic) Versus Conventional Radiotherapy for Inoperable Early Stage I Non-small Cell Lung Cancer (NSCLC) (CHISEL)

Non Small Cell Lung Cancer

Australia, New Zealand
AstraZeneca

Completed

A Study in Asthmatic Children (6 to <12 Yrs) Comparing Single Doses of Formoterol and Foradil® Evaluating Efficacy (CHASE 2)

Asthma

United States, South Africa, Hungary, Bulgaria, Czech Republic, Poland
Nasser Hanna, M.D.
Bayer; Amgen; Walther Cancer Institute

Terminated

Cisplatin/Etoposide/Radiotherapy Followed by Consolidation Sorafenib for Inoperable Stage III Non-Small Cell Lung Cancer

Non-Small Cell Lung Cancer

United States
Brno University Hospital
Masaryk University; Institute of Biostatistics and Analyses, Masaryk University... and other collaborators

Not yet recruiting

Obstetric Anaesthesia And Analgesia Month Attributes - in COVID-19 (OBAAMA-COV)

Obstetric Anesthesia Care

Czechia
University of Sheffield

Unknown

Anxiety Self-management Intervention for Pulmonary Hypertension

Anxiety Disorders | Anxiety | Pulmonary Arterial Hypertension | Pulmonary Hypertension

United Kingdom
The George Institute
Chinese University of Hong Kong; Monash University; The Alfred; University of Sydney and other collaborators

Recruiting

Statin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER)

Neurocognitive Impairment, Mild

Australia
Pharmaxis

Withdrawn

A Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPD

COPD | Exacerbation

Australia
GlaxoSmithKline

Completed

Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate is Processed by the Body in Healthy Caucasian, Japanese, Korean and Chinese Subjects

Asthma

Australia
GlaxoSmithKline

Completed

Study to Look at and Compare How Inhaled and Intravenous Fluticasone Furoate and GW642444 Are Processed by the Body in Healthy Subjects

Asthma

Australia
Medical University of South Carolina
Pandorum International, Inc.

Not yet recruiting

Mesenchymal Stromal Cells for COVID-19 and Viral Pneumonias (SAMPSON-1)

COVID-19 Pneumonia | Viral Pneumonia

United States

Clinical Trials on Lung in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Spain

Conditions

Rare Diseases

Drug Interventions

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