Clinical Trials on MAP2K2 Gene Mutation in Denmark

Total 38 results

Karen-Lise Garm Spindler

Completed

OPTImal PALliative Anti-epidermal Growth Factor Receptor Treatment in Metastatic Colorectal Cancer - (OPTIPAL-II)

Colorectal Cancer Metastatic | KRAS Gene Mutation | Circulating Tumor DNA | BRAF Gene Mutation | NRAS Gene Mutation | Epidermal Growth Factor Receptor Inhibitor

Denmark
Symphogen A/S

Completed

Sym015 (Anti-MET) in Patients With Advanced Solid Tumor Malignancies

NSCLC | Non Small Cell Lung Cancer | Oncology | MET Gene Mutation | MET Gene Amplification

United States, Korea, Republic of, Denmark, Hong Kong, Taiwan, Spain
Aarhus University Hospital
Roche Pharma AG

Enrolling by invitation

Monitoring Alectinib Treatment by Detection of ALK Translocations in Serial Blood Samples From Non-Small Cell Lung Cancer Patients (MonAlec)

Lung Cancer | ALK Gene Mutation | Resistance, Disease | Mutation

Denmark
Centre Leon Berard

Recruiting

Real Word European Registry of NTRK Fusions and Other Rare Actionable Fusions (TRacKING) (TRacKING)

Cancer | Cancer Metastatic | ALK Fusion Protein Expression | FGFR2 Gene Translocation | FGFR3 Gene Translocation | NTRK Family Gene Mutation | Gene Fusion | ROS1 Gene Translocation | NTRK Gene Fusion Overexpression | ATIC-ALK Fusion Protein Expression | BCR-FGFR1 Fusion Protein Expression | COL1A1-PDGFB Fusion... and other conditions

France, Denmark, Netherlands, Austria, Germany, Italy, United Kingdom, Czechia, Poland, Slovenia, Spain
University of Aarhus

Recruiting

Cystic Fibrosis in the Kidney: Monitoring the Effectiveness of Elexacaftor/Tezacaftor/Ivacaftor in Urine After a Short Pause of Therapy

Cystic Fibrosis (CF) | CFTR Gene Mutation

Denmark
Aarhus University Hospital

Unknown

Comparison of Two Surgical Techniques to Treat Knock Knees in Children

Genu Valgus

Denmark
Rigshospitalet, Denmark

Unknown

Clinical Importance of Carrier Status of Recessive Gene Mutations in Myopathy (CICS) (CICS)

Recessive Gene Myopathies

Denmark
Rigshospitalet, Denmark

Completed

Moderate Intensity Training in Patients With Truncating Genetic Variants in TTN.

Cardiomyopathies | TTN | Truncation Mutation

Denmark
University of Aarhus

Unknown

Stapling Versus 8plate for Correction of Genu Valgus

Deformity | Genu Valgus

Denmark
Aarhus University Hospital

Completed

Reconstruction of the Medial Patellofemoral Ligament - A Randomised Controlled Trial Comparing Two Surgery Technics

Knee Stability | Patella Luxation

Denmark
Kura Oncology, Inc.

Active, not recruiting

Safety and Efficacy of Tipifarnib in Head and Neck Cancer With HRAS Mutations and Impact of HRAS on Response to Therapy (AIM-HN/SEQ-HN)

HNSCC | HRAS Gene Mutation

United States, Belgium, Spain, United Kingdom, Taiwan, Denmark, Korea, Republic of, Netherlands, Thailand, Germany, Malaysia, Austria, Italy, Greece, Australia, Norway
Danish Head and Neck Cancer Group

Recruiting

DAHANCA 30: A Randomized Non-inferiority Trial of Hypoxia-profile Guided Hypoxic Modification of Radiotherapy of HNSCC. (DAHANCA30)

Hypoxia | Head and Neck Squamous Cell Carcinoma | Radiotherapy | Hypoxic Modification | Gene Profile, Gene Signature

Denmark
Matias Vested

Completed

Mivacurium 0.2 mg/kg in Young (18 - 40 Years) and Elderly (= 80 Years) Patients

Onset Time of Mivacurium, Duration of Action of Mivacurium

Denmark
Glostrup University Hospital, Copenhagen

Completed

Study of the: Effect of Head Rotation in Prone Position on Regional Cerebral Oxygen Saturation. (NIRS)

Regional Cerebral Oxygen Saturation During Head Rotation

Denmark
Matias Vested

Completed

An Observational Study of Cisatracurium 0.15 mg/kg in Young and Elderly (≥ 80 Years) Patients.

Intubation Conditions | Onset Time of Cisatracurium | Duration of Action of Cisatracurium

Denmark
University of Southern Denmark
Odense University Hospital

Recruiting

Pneumatic Tourniquet Versus no Tourniquet in Transfemoral Amputation

Amputation | Blood Loss

Denmark
Danish Pain Research Center
Pfizer

Completed

Gabapentin in Phantom and Stump Pain

Amputation of Lower Limb

Denmark
University of Copenhagen
Mental Health Services in the Capital Region, Denmark; Ministry of Social Affairs...

Completed

AID-trial Assertive Intervention After Deliberate Self-harm (AID)

Suicide, Attempted

Denmark
Kuopio University Hospital
Medical University of Vienna; Rigshospitalet, Denmark; University College, London and other collaborators

Active, not recruiting

Adenovirus Vascular Endothelial Growth Factor D (AdvVEGF-D) Therapy for Treatment of Refractory Angina Pectoris (ReGenHeart)

Coronary Artery Disease | Refractory Angina Pectoris | Gene Transfer

Denmark, Finland
University of Southern Denmark

Recruiting

The Effect of Negative Pressure Wound Therapy on Wound Healing in Major Amputations of the Lower Limb

Amputation | Wound Heal | Negative-Pressure Wound Therapy

Denmark
Rigshospitalet, Denmark

Not yet recruiting

Development of a Predictive Model for the Risk of Metastatic Disease in PPGLs, a Retrospective Cohort Study (PPGL-Pred)

Head and Neck Cancer | Genetic Predisposition to Disease | Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma | Pathology | Somatic Mutation

Denmark
Rigshospitalet, Denmark

Unknown

Postoperative Sleep Disturbances After Zolpidem Treatment in Fast-track Hip and Knee Replacement

Sleep Duration on the First Night After Surgery

Denmark
University of Copenhagen
University of Southern Denmark; Danish Research Centre for Magnetic Resonance; Faculty of Health, Medicine and Life Sciences, Maastricht University and other collaborators

Recruiting

Effect of Sleep Extension on Overweight and Learning in Children (More2Sleep)

Child Behavior | Child Development | Child Obesity | Sleep Duration

Denmark
Peloton Therapeutics, Inc., a subsidiary of Merck...

Active, not recruiting

A Phase 2 Study of Belzutifan (PT2977, MK-6482) for the Treatment of Von Hippel Lindau (VHL) Disease-Associated Renal Cell Carcinoma (RCC) (MK-6482-004)

VHL - Von Hippel-Lindau Syndrome | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL-Associated Renal Cell Carcinoma | VHL-Associated Clear Cell Renal Cell Carcinoma

United States, Denmark, United Kingdom, France
University of Southern Denmark
Region of Southern Denmark; The Danish Rheumatism Association; Esbjerg Municipality and other collaborators

Completed

Shoulder Exercises in Hypermobile Patients With Shoulder Symptoms

Hypermobility Syndrome Shoulder | Shoulder Pain Chronic | Shoulder Luxation

Denmark
Bayer

Recruiting

Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body (ON-TRK)

Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion

United States, Austria, Denmark, Germany, Italy, Norway, Spain, United Kingdom, Brazil, Russian Federation, Switzerland, Taiwan, Canada, China, Australia, Greece, Belgium, Sweden, Korea, Republic of, France, Argentina, Finland, Ireland and more
Danish Pain Research Center
Aarhus University Hospital

Completed

Postamputation Pain: Peripheral Mechanisms

Neuropathic Pain | Amputation, Traumatic | Phantom Limb Pain | Nerve Block | Stump Pain

Denmark
Pfizer

Completed

Transthyretin Amyloidosis Outcome Survey (THAOS) (THAOS)

Transthyretin Amyloidosis | Transthyretin Gene Mutations

United States, France, Spain, Taiwan, Israel, Korea, Republic of, Denmark, Canada, Netherlands, Japan, Sweden, Brazil, Mexico, Argentina, Portugal, Belgium, Bulgaria, Cyprus, Germany, Italy, Malaysia, Romania, Saudi Arabia, Turkey, United...
Morten Mau-Sørensen
Odense University Hospital; Aarhus University Hospital; Aalborg University Hospital

Recruiting

Trastuzumab and Standard Treatment With Chemo- and Immunotherapy as First Line Treatment for HER2 Positive Esophageal Squamous Cell Carcinoma Patients (HERES)

Esophageal Squamous Cell Carcinoma | HER-2 Gene Amplification | HER-2 Protein Overexpression

Denmark
Hvidovre University Hospital
Roskilde University

Recruiting

Time to Heal (Wound, Healing, Dialogue, Nutrition) (SNAK)

Leg Ulcer | Venous Leg Ulcer | Foot Ulcer, Diabetic | Amputation Stump | Arterial Leg Ulcer

Denmark
AstraZeneca
Daiichi Sankyo Co., Ltd.

Active, not recruiting

A Study of T-DXd for the Treatment of Solid Tumors Harboring HER2 Activating Mutations (DPT01)

Advanced Solid Tumors With HER2 Mutation,eg:Colorectal,Urothelial,Gastric, Hepatobiliary,Endometrial,Melanoma,Ovarian,Cervical,Salivary Gland,Pancreatic,Breast

Italy, Spain, United States, France, Korea, Republic of, Japan, Canada, Denmark, Belgium
Pfizer

Terminated

Javelin BRCA/ATM: Avelumab Plus Talazoparib in Patients With BRCA or ATM Mutant Solid Tumors

Locally Advanced or Metastatic Solid Tumors | Genes, BRCA 1

United States, Belgium, Spain, Denmark, Japan, France, Italy, Netherlands, United Kingdom
Puma Biotechnology, Inc.

Terminated

Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations (SUMMIT)

Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations

France, United States, Spain, Belgium, United Kingdom, Serbia, Australia, Israel, Canada, Denmark, Ireland, Italy, Korea, Republic of
Novartis Pharmaceuticals

Terminated

Phase III Study Investigating the Efficacy and Safety of Ruxolitinib in Early Myelofibrosis Patients With High Molecular Risk Mutations. (ReTHINK)

Myelofibrosis With High Molecular Risk Mutations

Belgium, Spain, United Kingdom, Hungary, Italy, Japan, Taiwan, Germany, Canada, Singapore, Austria, Australia, France, Israel, Sweden, Switzerland, Hong Kong, Greece, Turkey, Brazil, Russian Federation, Denmark, Portugal, Norway, Poland
Khondrion BV
Julius Clinical; ProPharma Group; Certara

Completed

The KHENEREXT Study

Mitochondrial Diseases | Mitochondrial DNA tRNALeu(UUR) m.3243A<G Mutation | Maternally Inherited Diabetes and Deafness (MIDD) | Mitochondrial Encephalomyopathy, Lactic Acidosis and Stroke Like Episodes (MELAS) | Chronic Progressive External Ophthalmoplegia (CPEO)

Netherlands, Denmark, United Kingdom, Germany
Astellas Pharma Global Development, Inc.

Completed

A Study of ASP2215 (Gilteritinib), Administered as Maintenance Therapy Following Induction/Consolidation Therapy for Subjects With FMS-like Tyrosine Kinase 3 (FLT3/ITD) Acute Myeloid Leukemia (AML) in First Complete Remission

Acute Myeloid Leukemia (AML) | Acute Myeloid Leukemia With FMS-like Tyrosine Kinase (FLT3) / Internal Tandem Duplication (ITD) Mutation

Taiwan, Poland, Serbia, United States, Brazil, Canada, Czechia, Denmark, France, Germany, Greece, Hungary, Israel, Italy, Japan, Korea, Republic of, Portugal, Romania, Spain, Sweden, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation (TRANSPORT)

Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

United States, France, Spain, Belgium, Canada, Austria, Australia, Germany, United Kingdom, Denmark
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Rollover Study of Lumacaftor in Combination With Ivacaftor in Subjects 12 Years and Older With Cystic Fibrosis

Cystic Fibrosis, Homozygous or Heterozygous for the F508del-CFTR Mutation

United States, France, United Kingdom, Germany, Spain, Belgium, Canada, Australia, Netherlands, Denmark, Czech Republic, Italy, Austria, Ireland, Sweden

Clinical Trials on MAP2K2 Gene Mutation in Denmark

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