Clinical Trials on MSI-H Solid Malignant Tumor

Total 6894 results

St. Jude Children's Research Hospital

Recruiting

Characterizing Sleep Among Long-term Survivors of Childhood Cancer

Solid Tumor | CNS Tumor | ALL, Adult

United States
Baxalta now part of Shire

Completed

Phase 1 Study of Anti-Macrophage Migration Inhibitory Factor (Anti-MIF) Antibody in Solid Tumors

Malignant Solid Tumors | Metastatic Adenocarcinoma of the Colon or Rectum

Germany, United States
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

Breast Cancer | Advanced Malignant Solid Tumors

United States, Taiwan, United Kingdom, Hong Kong, Belgium, France, Spain, China, Netherlands, Poland, Sweden
UNC Lineberger Comprehensive Cancer Center

Completed

Assessing Physical Fitness in Cancer Patients With Cardiopulmonary Exercise Testing and Wearable Data Generation

Malignant Solid Tumour | Hematologic Malignancies | Planned Hematopoietic Cell Transplantation

United States
Eli Lilly and Company

Completed

A Study of Enzastaurin in Chinese Patients With Advanced and/or Metastatic Solid Tumors or Lymphoma

Lymphoma, Malignant | Solid Tumor

China
Eli Lilly and Company

Completed

A Drug Interaction Study to Assess the Effect of LY317615 on the Metabolic Pathway of Warfarin

Lymphoma, Malignant | Solid Tumor

France
EpicentRx, Inc.

Completed

A Phase I, Open-Label, Multiple Ascending Dose Study of RRx-001 and Nivolumab (PRIMETIME)

Lymphoma | Malignant Solid Tumor

United States
Klinikum Klagenfurt am Wörthersee

Terminated

SBRT-based PArtial Tumor Irradiation of HYpoxic Segment (SBRT-PATHY)

Unresectable Malignant Solid Neoplasm | Bystander Effect | Abscopal Effect | Bulky Tumors

Austria
Immuneering Corporation

Recruiting

A Study of IMM-6-415 in RAS/RAF Mutant Solid Tumors

Pancreas Adenocarcinoma | Non-small Cell Lung Cancer | Advanced Solid Tumor (Phase 1) | Malignant Melanoma (Cutaneous)

United States
National Cancer Institute (NCI)

Active, not recruiting

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Histiocytic and Dendritic Cell Neoplasm | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Solid Neoplasm | Recurrent... and other conditions

United States, Puerto Rico
National Health Research Institutes, Taiwan
National Cheng-Kung University Hospital

Recruiting

Neoantigen Derived DCs as Cancer Treatment

Solid Tumor | Refractory Tumor

Taiwan
Massachusetts General Hospital
Boehringer Ingelheim; Incyte Corporation

Recruiting

Pemigatinib + Afatinib in Advanced Refractory Solid Tumors

Cholangiocarcinoma | Advanced Solid Tumor | Metastatic Solid Tumor | Unresectable Solid Tumor

United States
National Cancer Institute (NCI)
Children's Oncology Group

Active, not recruiting

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

Refractory Malignant Solid Neoplasm | Recurrent Ependymoma | Recurrent Ewing Sarcoma | Recurrent Hepatoblastoma | Recurrent Langerhans Cell Histiocytosis | Recurrent Malignant Germ Cell Tumor | Recurrent Malignant Glioma | Recurrent Malignant Solid Neoplasm | Recurrent Medulloblastoma | Recurrent Neuroblastoma and other conditions

United States, Puerto Rico, Australia
Sound Biopharmaceuticals Ltd.

Recruiting

Study in Patients With Advanced Solid Malignancies to Evaluate the Safety of FTL001

Solid Tumor

China
European Institute of Oncology

Recruiting

What Unmet Need for the Patients?A Focus on the Social Determinants of Health in Phase 1 Clinical Trials

Solid Tumor

Italy
Sidney Kimmel Comprehensive Cancer Center at Johns...
Personal Genome Diagnostics

Recruiting

Liquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Selection

Solid Tumor

United States
Impact Therapeutics, Inc.

Not yet recruiting

An BE Study to Compare 10mg & 20mg of IMP4297 Capsules in Healthy Chinese Subjects Under Fasting Condition

Solid Tumor
Impact Therapeutics, Inc.

Not yet recruiting

A Study of Absorption-Distribution-Metabolism-Excretion (ADME) of [14C]IMP4297 to China Healthy Male Subjects

Solid Tumor
University of Pennsylvania

Not yet recruiting

TumorGlow Intraoperative Molecular Imaging (IMI)

Tumor, Solid
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

A Prospective Study of the Relevance of the HLA-G Immune Checkpoint in Cancer Immunotherapy (GEIA)

Solid Tumor
Uppsala University Hospital

Recruiting

A MolEcularly Guided Anti-Cancer Drug Off-Label Trial (MEGALiT)

Solid Tumor

Sweden
Hoffmann-La Roche

Active, not recruiting

A Safety and Efficacy Extension Study of Pertuzumab in Patients With Solid Tumors Previously Enrolled in a Hoffmann-La Roche-Sponsored Pertuzumab Clinical Trial

Solid Tumor

Korea, Republic of, China, France, Portugal, Spain, Brazil, Germany, Italy, Peru, Russian Federation, Japan, Ukraine, Costa Rica, Mexico, Poland
Varian, a Siemens Healthineers Company

Completed

Varian ProBeam Proton Therapy System Clinical Trial (Shandong)

Tumor, Solid

China
Varian, a Siemens Healthineers Company

Completed

Varian ProBeam Proton Therapy System China Clinical Trial (Guangzhou)

Tumor, Solid

China
Abion Inc

Completed

To Evaluate the Safety, Pharmacokinetic and the Effect of Food After Administration of ABN401 in Healthy Adult Volunteers

Solid Tumor

Korea, Republic of
University of Wisconsin, Madison
National Cancer Institute (NCI); National Institutes of Health (NIH)

Terminated

Real-time Tumor Localization and Guidance for Radiotherapy Using Ultrasound (US) and Magnetic Resonance (MR)

Tumor, Solid

United States
Kite, A Gilead Company

Terminated

Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers

Solid Tumor

United States
Eikon Therapeutics
Seven and Eight Biopharmaceuticals Inc

Completed

BDB001-201: A Clinical Study of BDB001 in Patients With PD-(L)1 Refractory Solid Tumors

Tumor, Solid

United States
Refnot-Pharm Ltd

Completed

Effect of Refnot on Immunity in Cancer Patients (R-2)

Solid Tumor
Debiopharm International SA

Completed

Study to Assess Safety and Efficacy of the Second Mitochondrial-derived Activator of Caspases (SMAC) Mimetic Debio 1143 (SMARTPLUS-106)

Solid Tumor

United States, Spain, France
Jiangsu HengRui Medicine Co., Ltd.

Completed

Bioequivalence Study of Famitinib Malate in Healthy Volunteers Under Fasting Condition

Solid Tumor

China
Samsung Medical Center

Completed

Study to Evaluate the Safety and Efficacy of Gefitinib, in Subjects With EFGR Amplification Refractory Solid Tumors

Solid Tumor

Korea, Republic of
AnHeart Therapeutics Inc.

Completed

A Study of AB-106 in Chinese Healthy Adult Men Evaluated the Effects of Itraconazole and Rifampicin on AB-106 PK

Solid Tumor

China
Merck Sharp & Dohme LLC

Completed

Study of MK-4166 and MK-4166 in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4166-001)

Solid Tumor
Institut Claudius Regaud

Completed

Cohort Study: Modelling Toxicity Processing in Patients Treated by Immunotherapy (MOTIVATE). (MOTIVATE)

Solid Tumor

France
Kyunghee University Medical Center

Unknown

Safety of the Combination of SH003 and Docetaxel in Patients With Solid Cancer

Solid Tumor
Merck Sharp & Dohme LLC

Terminated

A Study of the Safety, Tolerability, and Efficacy of MK-8353 in Participants With Advanced Solid Tumors (MK-8353-001)

Tumor, Solid
Samsung Medical Center

Withdrawn

Phase II Trial of AZD2014 in RICTOR Amplified Solid Cancer Patients Refractory to Standard Chemotherapy (RICTOR_SC)

Solid Tumor

Korea, Republic of
Gilead Sciences

Completed

Phase 1 Trial of Hu5F9-G4, a CD47-targeting Antibody

Solid Tumor

United States
Samsung Medical Center

Completed

Study to Evaluate the Safety and Efficacy of Everolimus, in Subjects With PIK3CA Amplification, PTEN Loss and PIK3CA Mutation Refractory Solid Tumors

Solid Tumor

Korea, Republic of
Merck Sharp & Dohme LLC
Ariad Pharmaceuticals

Completed

Trial of Deforolimus in Combination With Bevacizumab for Patients With Advanced Cancers (8669-010)(COMPLETED)

Solid Tumor
National University Hospital, Singapore

Completed

Pharmacokinetic Study of CPT-11, Raltegravir and Midazolam With Characterisation of UGT1A1 Genotype

Solid Tumor

Singapore
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Completed

Effects of Epidermal Growth Factor Receptor Inhibitor Therapy in the Skin of Cancer Patients

Solid Tumor

United States
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Phase I Clinical Study of SHR-5495 in the Treatment of Patients With Advanced Malignant Tumors

Advanced Malignant Tumor

China
Shanghai Junshi Bioscience Co., Ltd.
Sponsor GmbH

Not yet recruiting

The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of JS207 in Patients With Advanced Malignant Tumor

Advanced Malignant Tumor

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

A Study of HRS7415 Tablets in Patients With Advanced Malignant Tumors

Advanced Malignant Tumor
Chia Tai Tianqing Pharmaceutical Group Nanjing...

Recruiting

Clinical Trial of TQB2868 Injection in Subjects With Advanced Malignant Tumors

Advanced Malignant Tumor

China
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Recruiting

A Clinical Trial of TQB3909 Tablets in Subjects With Advanced Malignant Tumors

Advanced Malignant Tumor

China
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.

Suspended

A Study to Evaluate the Cardiac Safety of Mitoxantrone Hydrochloride Liposome Injection in the Treatment of Advanced Malignant Tumor

Advanced Malignant Tumor

China
Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Recruiting

A Study of DCR-STAT3 in Adults With Solid Tumors

Solid Tumor, Adult | Refractory Tumor

United States

Clinical Trials on MSI-H Solid Malignant Tumor

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