Clinical Trials on Malignant Glioma

Total 6830 results

University Medical Center Groningen

Not yet recruiting

Social Cognition and Language in Patients With Gliomas

Cognitive Dysfunction | Glioma, Malignant
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI)

Completed

Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors

Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Refractory Diffuse Intrinsic Pontine Glioma | CNS Embryonal Tumor, Not Otherwise Specified

United States
University of Miami

Recruiting

Non-invasive Glioma Characterization Through Molecular Imaging

Glioma | Brain Tumor | Malignant Glioma | Primary Brain Tumor | Malignant Primary Brain Tumor

United States
National Cancer Institute (NCI)

Terminated

Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV Melanoma

Recurrent Melanoma | Stage IV Melanoma | Acral Lentiginous Malignant Melanoma | Lentigo Maligna Malignant Melanoma | Nodular Malignant Melanoma | Solar Radiation-related Skin Melanoma | Superficial Spreading Malignant Melanoma

United States
Mayo Clinic
National Cancer Institute (NCI)

Terminated

Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy

Malignant Glioma | WHO Grade 3 Glioma | Intractable Epilepsy | Seizure Disorder | WHO Grade 2 Glioma

United States
Sklifosovsky Institute of Emergency Care

Recruiting

Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases (CONFLUENSE)

Glioma, Malignant | Metastases to Brain

Russian Federation
Eli Lilly and Company
Genentech, Inc.

Completed

Trial of Enzastaurin and Bevacizumab in Participants With Recurrent Malignant Gliomas

Recurrent Glioblastoma

United States
Baptist Health South Florida
Ion Beam Applications SA

Not yet recruiting

PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial (POPCORN)

Glioma | Recurrent Glioma | Glioma, Malignant

United States
National Cancer Institute (NCI)
M.D. Anderson Cancer Center; Washington University School of Medicine; Merck... and other collaborators

Completed

Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma

Malignant Glioma | Recurrent Glioblastoma

United States
Huazhong University of Science and Technology
Beijing Friendship Hospital; Beijing Tiantan Hospital; Beijing Chao Yang Hospital

Completed

ADV-TK Improves Outcome of Recurrent High-Grade Glioma (HGG-01)

Glioblastoma | Malignant Glioma of Brain

China
Northwestern University
National Cancer Institute (NCI); AstraZeneca; MedImmune LLC

Completed

Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma

Malignant Glioma | Recurrent Glioblastoma

United States
Children's Oncology Group
National Cancer Institute (NCI); Incuron LLC

Recruiting

CBL0137 for the Treatment of Relapsed or Refractory Solid Tumors, Including CNS Tumors and Lymphoma

Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Osteosarcoma | Refractory Osteosarcoma | Diffuse Midline Glioma, H3 K27M-Mutant | Recurrent Diffuse Intrinsic Pontine Glioma | Metastatic Malignant Neoplasm in the Central... and other conditions

United States
Children's Hospital Los Angeles
Dana-Farber Cancer Institute

Active, not recruiting

Study of MEK162 for Children With Low-Grade Gliomas

Soft Tissue Neoplasms | Low-Grade Gliomas | Malignant Neoplasms, Brain

United States
Massachusetts General Hospital
Conquer Cancer Foundation

Completed

Psychological Intervention For Brain Tumor Caregivers

Anxiety | Caregiver Burden | Malignant Glioma | Malignant Brain Tumor

United States
Duke University
TerSera Therapeutics

Completed

Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide

Chemo-radiation Induced Nausea and Vomiting

United States
Duke University

Terminated

Procedural Outcomes in Endobronchial Ultrasound - Transbronchial Needle Aspiration (EBUS-TBNA) With and Without Rapid On-Site Evaluation (ROSE) (ROSE)

ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION | Benign and Malignant Mediastinal and Hilar Lymph Nodes Known or Suspected Malignancy

United States
Ikena Oncology

Recruiting

Study of IK-595 in RAS- or RAF-altered Advanced Tumors

Colorectal Cancer | Pancreatic Cancer | Thyroid Carcinoma | Solid Tumor, Adult | Malignant Melanoma | Non-Small Cell Lung Carcinoma | BRAF Gene Mutation | Gliomas, Malignant | Ras (Kras or Nras) Gene Mutation | CRAF Gene Mutation

United States
Shandong Lanjin Pharmaceuticals Co.,Ltd

Unknown

Safety and Efficacy Study of Intracranially Implanted Carmustine to Treat Recurrent Malignant Glioma

Glioblastoma | Anaplastic Oligoastrocytoma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma

China
TransMolecular

Unknown

131-I-TM-601 Study in Adults With Recurrent High-Grade Glioma

Glioblastoma Multiforme | Malignant Glioma | Gliosarcoma | GBM | Anaplastic Astrocytoma | Oligo-Astrocytoma

United States
Novelwise Pharmaceutical Corporation

Recruiting

NBM-BMX Administered Orally to Patients With Solid Tumors or Newly Diagnosed Glioblastoma

Malignant Neoplasm | Malignant Neoplasm of Brain

Taiwan
Sociedad de Lucha Contra el Cáncer del Ecuador

Not yet recruiting

5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas

Glioma | Neoplasms, Neuroepithelial | Neuroectodermal Tumors | Central Nervous System Neoplasms | Brain Tumor | High Grade Glioma | Glioma, Malignant | Neoplasm Malignant | Photosensitizing Agents | Tumour, Residual | Brain Neoplasms, Adult, Malignant

Ecuador
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Study Of Vinblastine in Combination With Nilotinib in Children, Adolescents and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies

Glioblastoma | Anaplastic Astrocytoma | Oligodendroglioma | Diffuse Astrocytoma | Anaplastic Oligodendroglioma | Metastatic Malignant Neoplasm in the Brain | Diffuse Glioma

United States
Gustave Roussy, Cancer Campus, Grand Paris
Innovative Therapies For Children with Cancer Consortium

Terminated

Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
Northwell Health

Recruiting

Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma

Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme, Adult

United States
Pediatric Brain Tumor Consortium
National Cancer Institute (NCI); NovoCure Ltd.; American Lebanese Syrian Associated...

Recruiting

Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG

Malignant Glioma | Ependymoma | Diffuse Intrinsic Pontine Glioma

United States
Constantinos Hadjipanayis
National Cancer Institute (NCI); NX PharmaGen

Withdrawn

More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery

Glioblastoma | Brain Cancer | Brain Tumors | Brain Tumor, Recurrent | Benign Neoplasms, Brain | Brain Neoplasms, Benign | Brain Neoplasms, Malignant | Brain Tumor, Primary | Intracranial Neoplasms | Neoplasms, Brain | Neoplasms, Intracranial | Primary Brain Neoplasms | Primary Malignant Brain Neoplasms | Primary Malignant... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Not yet recruiting

Dexamethasone and Azeliragon for Management of Post-Resection Cerebral Edema in Patients With Glioblastoma

Glioblastoma | Malignant Glioma

United States
Chimerix

Active, not recruiting

ONC201 in Pediatric H3 K27M Gliomas

Diffuse Intrinsic Pontine Glioma | Glioma, Malignant

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Multiple Doses of Neural Stem Cell Virotherapy (NSC-CRAd-S-pk7) for the Treatment of Recurrent High-Grade Gliomas

Recurrent Glioblastoma | Recurrent Malignant Glioma | Recurrent WHO Grade III Glioma | Recurrent WHO Grade II Glioma | Recurrent Gliosarcoma | Recurrent Anaplastic Astrocytoma | Recurrent Anaplastic Oligoastrocytoma | Recurrent Anaplastic Oligodendroglioma

United States
University of Florida
National Cancer Institute (NCI)

Completed

Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme (ATTAC-II)

Glioblastoma | Glioblastoma Multiforme | Malignant Glioma | GBM | Astrocytoma, Grade IV

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI); NeoImmuneTech

Terminated

Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas

Malignant Glioma | Lymphopenia

United States
INSYS Therapeutics Inc

Completed

Imaging Study of the Distribution of IL13-PE38QQR Infused Before and After Surgery in Adult Patients With Recurrent Malignant Glioma

Glioblastoma Multiforme | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Mixed Oligoastrocytoma

United States
Beijing Neurosurgical Institute

Recruiting

ZOOMit-fMRI Identifies Motor Functional Cortex

Gliomas

China
Nanfang Hospital, Southern Medical University

Recruiting

Efficacy and Safety of Rivaroxaban in the Prevention of Venous Thromboembolism in Glioma Patients

Glioma, Malignant

China
M.D. Anderson Cancer Center
BioMed Valley Discoveries, Inc

Recruiting

Window-of-Opportunity Trial of Ulixertinib for MAPK-Activated Low-Grade Gliomas in Adults

Gliomas

United States
Drexel University College of Medicine

Completed

A Phase II Study of Adjuvant Use of Anti-Epidermal Growth Factor Receptor EGFR-425 in High Grade Gliomas

Gliomas

United States
Universitaire Ziekenhuizen KU Leuven

Completed

Advanced MR Techniques in Detection of Tumor Infiltration and Grading in Gliomas

Gliomas

Belgium
Beijing Tiantan Hospital

Not yet recruiting

Clinical Study of Allogeneic Vγ9Vδ2 T Cells in the Treatment of Brain Malignant Glioma (CSAγδTBMG)

Medulloblastoma | GBM | DIPG Brain Tumor

China
National Cancer Institute (NCI)

Suspended

A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Glioblastoma | Malignant Glioma | Anaplastic Astrocytoma | Anaplastic Astrocytoma, Not Otherwise Specified | Diffuse Intrinsic Pontine Glioma | Diffuse Midline Glioma, H3 K27M-Mutant | Glioblastoma, Not Otherwise Specified

United States, Canada, Australia, New Zealand
Children's Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas

Malignant Glioma | WHO Grade 3 Glioma | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Refractory Primary Central Nervous System Neoplasm | Recurrent Childhood Central Nervous System Neoplasm | Recurrent Brain Neoplasm | Recurrent Childhood...

United States
Thomas Jefferson University

Recruiting

Analysis of Cell Count, Viability, and Immunogenicity of Discarded Newly Diagnosed Glioblastoma Tissue or Solid Tumor Tissues

Malignant Solid Neoplasm | Glioblastoma

United States
Indiana University

Terminated

Pilot Study of Cabozantinib for Recurrent or Progressive Central Nervous System Tumors in Children

Glioblastoma Multiforme | High Grade Glioma | Anaplastic Astrocytoma | Malignant Brain Tumor

United States
Polaris Group

Terminated

Ph 1 Study in Subjects With Tumors Requiring Arginine to Assess ADI-PEG 20 With Pemetrexed and Cisplatin (TRAP)

Glioma | Hepatocellular Carcinoma | Uveal Melanoma | Sarcomatoid Carcinoma | Pleural Mesothelioma Malignant Advanced | Peritoneal Mesothelioma Malignant Advanced | Non-squamous Non-small Cell Lung Carcinoma

United States, United Kingdom
Northwell Health

Recruiting

Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM)

Glioma | Glioblastoma | Brain Cancer | Glioblastoma Multiforme | High Grade Glioma | GBM | Glioma, Malignant | Glioblastoma Multiforme of Brain

United States
Eben Rosenthal
National Cancer Institute (NCI)

Terminated

Cetuximab-IRDye 800CW in Detecting Tumors in Patients With Malignant Glioma Undergoing Surgery

Malignant Glioma | Brain Neoplasm

United States
Dushu Lake Hospital Affiliated to Soochow University

Recruiting

Clinical Study on the Treatment of Malignant Brain Glioma by QH104 Cell Injection

Brain Gliomas

China
Memorial Sloan Kettering Cancer Center
Genentech, Inc.; National Institutes of Health (NIH)

Completed

Bevacizumab, Temozolomide and Hypofractionated Radiotherapy for Patients With Newly Diagnosed Malignant Glioma

Brain Cancer | Malignant Glioma

United States
medac GmbH
IKP

Completed

Clinical Study on 5-aminolevulinic Acid Hydrochloride (5-ALA) for Fluorescence-guided Resection of Malignant Gliomas

Brain Neoplasm
M.D. Anderson Cancer Center

Withdrawn

Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer

Malignant Glioma | Medulloblastoma | Anaplastic Ependymoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Atypical Teratoid/Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Recurrent Atypical Teratoid/Rhabdoid Tumor | Malignant Brain Neoplasm | Central Nervous System... and other conditions

United States

Clinical Trials on Malignant Glioma

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Uruguay

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations