Clinical Trials on Malignant Neoplasms

Total 106824 results

Syndax Pharmaceuticals

Completed

A Phase 1 Study to Investigate SNDX-6352 Alone or in Combination With Durvalumab in Patients With Solid Tumors

Solid Tumor | Unresectable Malignant Neoplasm | Locally Advanced Malignant Neoplasm | Metastatic Tumor

United States
Fox Chase Cancer Center

Recruiting

Adaptive Radiation for Abdominopelvic Metastases

Malignant Neoplasm of Stomach | Neoplasm - Soft Tissue Pelvis Malignant Secondary

United States
Shoichi Fujii, MD, PhD

Unknown

Randomized Controlled Trial Between Laparoscopic and Open Surgery in Transverse and Descending Colon Cancer Patients

Malignant Neoplasm of Transverse Colon | Malignant Neoplasm of Descending Colon

Japan
Daniel M. Spielman
National Cancer Institute (NCI); National Institutes of Health (NIH)

Completed

Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors

Malignant Central Nervous System Neoplasm | Metastatic Malignant Neoplasm in the Central Nervous System

United States
University of Minnesota

Recruiting

Radioembolization of Primary and Secondary Liver Malignancies and The Effect On The Immune System

Hepatocellular Carcinoma | Secondary Malignant Neoplasm of Liver

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Recruiting

Blood Samples to Identify Biomarkers in Patients Treated With Cyclophosphamide After Donor Stem Cell Transplant

Malignant Neoplasm | Allogeneic Hematopoietic Stem Cell Transplant Recipient | Donor

United States
Huazhong University of Science and Technology

Recruiting

Study of Targeted Therapy Using Transcription Activator-like Effector Nucleases in Cervical Precancerous Lesions

Human Papillomavirus-Related Malignant Neoplasm

China
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Fat Emulsion in Preventing Hypersensitivity Reactions in Patients With Cancer Receiving Carboplatin or Oxaliplatin

Advanced Malignant Neoplasm

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Psycho-Educational Program in Increasing Knowledge and Satisfaction and Decreasing Distress in Younger Patients With Cancer Receiving Treatment

Malignant Neoplasm | Psychosocial Effects of Cancer and Its Treatment

United States
Tata Memorial Hospital

Completed

Tomotherapy in Locally Advanced Gallbladder and Pancreatic Cancers

Pancreatic Neoplasms Malignant | Malignant Neoplasm of Gall Bladder Non-resectable

India
Roswell Park Cancer Institute

Recruiting

Single-Fraction SBRT Versus Standard Palliative Radiation Therapy in Treating Patients With Metastatic Cancer

Metastatic Malignant Neoplasm

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Ketoconazole in Treating Participants With Ongoing EGFR Inhibitor-Induced Rash

Malignant Neoplasm

United States
Julie L. Sutcliffe, Ph.D
National Cancer Institute (NCI)

Active, not recruiting

First-in-Human Positron Emission Tomography Study Using the 18F-αvβ6-Binding-Peptide

Breast Carcinoma | Lung Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Metastatic Malignant Neoplasm in the Lung | Metastatic Malignant Neoplasm in the Breast | Metastatic Malignant Neoplasm in the Colon | Metastatic Malignant Neoplasm in the Rectum

United States
Groupe Français de Pneumo-Cancérologie
Bristol-Myers Squibb

Active, not recruiting

Observational Study in Patients With Previously Unresectable Malignant Pleural Mesothelioma Treated With Nivolumab and Ipilimumab (MESO-IMMUNE) (MESO-IMMUNE)

Malignant Pleural Mesothelioma | Unresectable Malignant Neoplasm

France
Soonchunhyang University Hospital
Seoul National University Hospital; SMG-SNU Boramae Medical Center; Saint Vincent... and other collaborators

Recruiting

Abscopal Effect From the Low-dose Radiotherapy in Polymetastatic Cancer Patients Receiving Stereotactic Radiotherapy (KROG22-11)

Neoplasms | Secondary Malignant Neoplasm

Korea, Republic of
M.D. Anderson Cancer Center
National Cancer Institute (NCI); National Institute of Nursing Research (NINR)

Recruiting

Cordotomy in Reducing Pain in Patients With Advanced Cancer

Advanced Malignant Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Cryoablation for the Treatment of Metastatic Cancer

Metastatic Malignant Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Unknown

Survey of Cancer Patients' Perceptions of Difficulties Encountered When Filling Opioid Prescriptions

Pain | Malignant Neoplasm

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); National Heart, Lung, and Blood Institute...

Completed

Donor Atorvastatin Treatment for Preventing Severe Acute Graft-Versus-Host Disease in Patients Undergoing Myeloablative Peripheral Blood Stem Cell Transplantation

Malignant Neoplasm

United States
Huazhong University of Science and Technology

Unknown

Study of Molecular-targeted Therapy Using Zinc Finger Nuclease in Cervical Precancerous Lesions

Human Papillomavirus-Related Malignant Neoplasm

China
Jonsson Comprehensive Cancer Center
AstraZeneca

Active, not recruiting

Brachytherapy With Durvalumab or Tremelimumab for the Treatment of Patients With Platinum-Resistant, Refractory, Recurrent, or Metastatic Gynecological Malignancies

Metastatic Malignant Female Reproductive System Neoplasm | Platinum-Resistant Malignant Female Reproductive System Neoplasm | Recurrent Malignant Female Reproductive System Neoplasm | Refractory Malignant Female Reproductive System Neoplasm

United States
Tianjin Chasesun Pharmaceutical Co., LTD

Enrolling by invitation

A Study of IMMH-010 in Patients With Advanced Malignant Solid Tumors

Malignant Neoplasms

China
Sanofi

Completed

Effect of Cabazitaxel on the QTc Interval in Cancer Patients (QT-Cab)

Neoplasms, Malignant

United States, Belgium, Denmark, Netherlands, Sweden
Fred Hutchinson Cancer Center
National Institute of Nursing Research (NINR); Peacefully, Inc.

Not yet recruiting

Design and Testing of a Web-Based Tool for the Improvement of End-of-Life Planning in Patients With Advanced Cancer

Hematopoietic and Lymphoid System Neoplasm | Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Tasly Biopharmaceuticals Co., Ltd.

Not yet recruiting

A Study of B1962, a PD-L1/VEGF Bispecific Antibody Fusion Protein, for Advanced Solid Tumors

Neoplasms Malignant

China
Avid Radiopharmaceuticals

Recruiting

Early Clinical Evaluation of 18F-LY3546117 in Tumor Imaging

Neoplasms | Neoplasms Malignant

Australia
Sanofi

Completed

A Study to Investigate the Disposition of Radio-labeled AVE8062 Compound Administered as a 30-minute IV Infusion to Patients With Advanced Solid Tumor

Neoplasms, Malignant

Belgium
Sanofi

Completed

Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Cisplatin in Patients With Solid Tumors

Neoplasms, Malignant

Japan
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Neratinib and Everolimus, Palbociclib, or Trametinib in Treating Participants With Refractory and Advanced or Metastatic Solid Tumors With EGFR Mutation/Amplification, HER2 Mutation/Amplification, or HER3/4 Mutation or KRAS Mutation

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | KRAS Gene Mutation | Metastatic Malignant Solid Neoplasm | EGFR Gene Mutation | ERBB2 Gene Amplification | ERBB2 Gene Mutation | EGFR Gene Amplification | ERBB3 Gene Mutation | ERBB4 Gene Mutation

United States
Icahn School of Medicine at Mount Sinai
M.D. Anderson Cancer Center; Emory University

Recruiting

A Multi Center Study of Sexual Toxicities After Radiotherapy (STAR)

Malignant Neoplasms

United States
Akesobio Australia Pty Ltd

Recruiting

A Study of AK112, a PD-1/VEGF Bispecific Antibody, for Advanced Solid Tumors

Neoplasms Malignant

Australia
Sanofi

Completed

Dose-escalation, Safety, Pharmacokinetics Study of AVE8062 Combined With Bevacizumab in Patients With Advanced Solid Tumors

Neoplasms, Malignant

France, United Kingdom, Italy
Sanofi

Completed

Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Docetaxel and Cisplatin in Patients With Solid Tumors

Neoplasms, Malignant

Japan
Sanofi

Terminated

Dose-Escalation, Safety, Pharmacokinetics Study of Cabazitaxel With Gemcitabine In Patients With Solid Tumor

Neoplasms, Malignant

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Talazoparib in Treating Patients With Recurrent, Refractory, Advanced, or Metastatic Cancers and Alterations in the BRCA Genes

BRCA1 Gene Mutation | BRCA2 Gene Mutation | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | PALB2 Gene Mutation | ATM Gene Mutation

United States
National Cancer Institute (NCI)

Withdrawn

Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants With Pleural Mesotheliomas, or Pleural Effusions From Cancers Expressing Mesothelin

Malignant Pleural Mesotheliomas (Mpm) | Malignant Pleural Effusions (Mpe) | Epithelial Tumors, Malignant | Pleural Effusions, Malignant | Mesothelin (Msln)

United States
Ohio State University Comprehensive Cancer Center

Recruiting

Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Metastatic Malignant Neoplasm in the Spine

United States
Columbia University

Recruiting

Comparison of the Breast Tumor Microenvironment

Triple Negative Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Lung Carcinoma | Malignant Respiratory Tract Neoplasm | Metastatic Malignant Neoplasm in the Lung

United States
National Cancer Institute (NCI)

Suspended

Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Endometrial Cancer

Unresectable Malignant Solid Neoplasm | Endometrial Serous Adenocarcinoma | Metastatic Malignant Solid Neoplasm

United States
University of Edinburgh
NHS Lothian

Completed

Thermal Testing in Bone Pain (TiBoP) (TiBoP)

Pain | Toxicity Due to Radiotherapy | Cancer Induced Bone Pain | Secondary Malignant Neoplasm of Bone

United Kingdom
OHSU Knight Cancer Institute
Oregon Health and Science University

Available

Bone Marrow Transplantation Using CD34-Selected Stem Cells From Related or Unrelated Donors in Treating Participants With Cancer or Other Disorders

Malignant Neoplasm | Hematopoietic Cell Transplantation Recipient | Benign Neoplasm | Bone Marrow Transplantation Recipient

United States
University of Utah

Active, not recruiting

Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer (SOAR)

Prostate Adenocarcinoma | Metastatic Malignant Neoplasm in the Bone | Metastatic Malignant Neoplasm in the Lymph Nodes | Recurrent Prostate Carcinoma | Oligometastasis | PSA Failure

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases

Malignant Neoplasm | Metastatic Malignant Neoplasm in the Brain

United States
The Cleveland Clinic

Completed

Impact of Perioperative Intravenous Fluid Utilization on Postoperative Outcomes

Benign Neoplasm of Intestinal Tract | Primary Malignant Neoplasm of Intestinal Tract | Secondary Malignant Neoplasm of Intestinal Tract

United States
University of Pecs

Completed

Role of PET/MRI in Head and Neck Cancer

Head and Neck Cancer | Malignant Neoplasm | Benign Neoplasm
National Cancer Institute (NCI)

Terminated

EF5 in Detecting Oxygen Level and Blood Vessels in Tumor Cells of Patients Undergoing Photodynamic Therapy for Intraperitoneal or Pleural Cancer

Primary Peritoneal Cavity Cancer | Malignant Ascites | Recurrent Malignant Mesothelioma | Advanced Malignant Mesothelioma | Localized Malignant Mesothelioma

United States
Jules Bordet Institute
University Hospital, Ghent

Completed

Comparing Hepatic Intra-arterial Injection of Yttrium-90 Microspheres Versus Fluorouracil (5FU) in Colorectal Cancer Metastatic to the Liver Only

Colorectal Neoplasm | Secondary Malignant Neoplasm of Liver

Belgium
Thomas Jefferson University

Recruiting

Evaluation of Sleep Quality in Head and Neck Cancer Patients Throughout Treatment Course

Malignant Head and Neck Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

3D Printed Oral Stents for Patients With Head and Neck Cancer Receiving Radiation Therapy

Malignant Head and Neck Neoplasm

United States

Clinical Trials on Malignant Neoplasms

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CROs in Greece

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