Clinical Trials on Mediastinal Diseases

Total 381142 results

Rennes University Hospital

Completed

Mediastinitis and Staphylococcus Aureus (MEDIASTAPH)

Infection | Surgery, Cardiac

France
Clinical Center of Vojvodina

Completed

Prognostic Factors for Descending Necrotizing Mediastinitis Development in Deep Space Neck Infections

Inflammation | Infection | Mediastinitis | Neck Abscess
Intuitive Surgical

Active, not recruiting

Clinical Investigation of the da Vinci Surgical System

Gynecologic Cancer | Inguinal Hernia | Thymoma | Pelvic Organ Prolapse | Prostate Cancer | Obesity, Morbid | Ventral Hernia | Gynecologic Disease | Prostate Disease | Mediastinal Tumor

United States
American Society for Gastrointestinal Endoscopy
Midwest Biomedical Research Foundation

Unknown

A Randomized Controlled Trial Of Endoscopic Ultrasound-Guided Fine-Needle Aspiration With And Without A Stylet

Mediastinal or Intra-abdominal Lymphadenopathy, | Pancreatic Masses, | Left Adrenal Masses, | Gastrointestinal Submucosal Lesions, and | Liver Masses

United States
Duke University
KLS Martin, L.P.

Completed

Rapid Sternal Closure System (TALON) (TALON)

Mediastinitis | Sternal Wound Infection

United States
University of Calgary

Completed

Endobronchial Ultrasonography in the Diagnosis of Sarcoidosis

Sarcoidosis | Mediastinal Diseases

Canada
Texas Tech University Health Sciences Center, El...

Completed

The Cellularity Yield of Three Different 22-gauge FNA Needles

Pancreatic or Peripancreatic Lesions | Lesions in the Esophagus, Stomach, Duodenum or Rectum | Mediastinal ( Chest) Masses | Enlarged Lymph Nodes

United States
Università Vita-Salute San Raffaele

Recruiting

Laboratory Biomarkers and Pulmonary Interstitial Emphysema in ARDS (PIE-ARDS) (PIE-ARDS)

Acute Respiratory Distress Syndrome | Barotrauma

Italy
University of Lausanne Hospitals
University Hospital Olomouc

Unknown

Delayed Primary Versus Late Secondary Wound Closure in Sternum Infections

Mediastinitis

Switzerland
David Bond, MD
Bristol-Myers Squibb

Active, not recruiting

Nivolumab With DA-REPOCH Chemotherapy Regimen in Treating Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

Diffuse Large B-Cell Lymphoma | Aggressive Non-Hodgkin Lymphoma | Indolent Non-Hodgkin Lymphoma | Ann Arbor Stage IV B-Cell Non-Hodgkin Lymphoma | High Grade B-Cell Lymphoma, Not Otherwise Specified | Transformed Non-Hodgkin Lymphoma | Ann Arbor Stage II B-Cell Non-Hodgkin Lymphoma | Ann Arbor Stage... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Completed

Chemoembolization for Lung Tumors

Lung Metastases | Endobronchial Metastases | Pleural Metastases | Mediastinal Metastases

United States
Zimmer Biomet

Completed

Evaluation of Primary Plating in Sternotomy Patients for Osteosynthesis and Pain (RESTORE)

Pain | Mediastinitis | Sternal Wound Infection | Sternal Non-union

United States, Germany
Hospices Civils de Lyon

Completed

Mediastinal Grey Zone Lymphoma From the LYSA

Mediastinal Grey Zone Lymphoma

France
University Hospital, Essen
Epigenomics, Inc

Completed

Methylation Level of SHOX2 in Endobronchial Ultrasound With Real-time Guided Transbronchial Needle Aspiration for Lung Cancer Staging

Lung Cancer With Mediastinal Lymph Node Involvement

Germany
Rambam Health Care Campus

Unknown

Hybrid SPECT/CTCA for the Assessment of the Presence and Hemodynamic Significance of CAD in Asymptomatic Patients.

Hodgkin Lymphoma Treated With Mediastinal Irradiation

Israel
Far Eastern Memorial Hospital

Completed

Topical Vancomycin in Prevention of Methicillin-Resistant Staphylococcal Related Mediastinitis in Patients Receiving Coronary Artery Bypass Graft

Coronary Artery Disease

Taiwan
National Cancer Institute (NCI)

Active, not recruiting

Copanlisib Hydrochloride and Nivolumab in Treating Patients With Recurrent or Refractory Diffuse Large B-cell Lymphoma or Primary Mediastinal Large B-cell Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal Large B-Cell Lymphoma | Refractory Primary Mediastinal Large B-Cell Lymphoma

United States
University Hospital, Toulouse

Recruiting

Clinical Impact of Thoracic Scanographic Characteristics of Hematologic Malignancy Patients (MED-HEM)

Mediastinal Diseases

France
International Extranodal Lymphoma Study Group (IELSG)

Active, not recruiting

Randomized, Open-label, Two-arms, Phase III Comparative Study Assessing the Role of Involved Mediastinal Radiotherapy After Rituximab Containing Chemotherapy Regimens to Patients With Newly Diagnosed Primary Mediastinal Large B-Cell Lymphoma

Primary Mediastinal B-cell Lymphoma

Norway, United Kingdom, Italy, Switzerland, Czechia, United States, China, Argentina, Canada, Germany, Poland, Portugal, Sweden, Ukraine
National Cancer Institute (NCI)

Recruiting

Nivolumab in Combination With Chemo-Immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-Cell Lymphoma

Primary Mediastinal Large B-Cell Lymphoma

United States, Canada, Australia, Puerto Rico
Abramson Cancer Center of the University of Pennsylvania

Completed

Intraoperative Imaging With ICG Registry

Lung Nodule, Breast, Kidney,Parathyroid, Mediastinal, Skin Mass, Soft Tissue, Prostate, Stomach Pleural, Head and Neck, and Are at Risk of Recurrence

United States
Sun Yat-sen University

Not yet recruiting

A Prospective Study: Sintilimab and R-CHOP in PMBCL Treatment

Primary Mediastinal Large B Cell Lymphoma
Gustave Roussy, Cancer Campus, Grand Paris
Children's Oncology Group

Active, not recruiting

Intergroup Trial for Children or Adolescents With Primary Mediastinal Large B-Cell Lymphoma: DA-EPOCH-Rituximab Evaluation

Primary Mediastinal Large B Cell Lymphoma

France, Belgium, United Kingdom, Netherlands, Canada, Hungary, Italy, Poland, Spain
Chinese PLA General Hospital

Unknown

Two Stage Study of Combination of Chemotherapy, SHR-1210 and/or Decitabine for Relapsed/Refractory PMBCLs

Primary Mediastinal Large B-cell Lymphoma

China
Fondazione Italiana Linfomi ONLUS

Completed

A Study of SGN-35 (Brentuximab Vedotin) of Patients With Relapsed or Refractory PMLBCL (FIL_SGN01)

Primary Mediastinal Large B Cell Lymphoma

Italy
Nasser Hanna, M.D.
Merck Sharp & Dohme LLC; Hoosier Cancer Research Network

Terminated

Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors

Genital Neoplasms, Female | Testicular Neoplasms | Genital Neoplasms, Male | Ovarian Neoplasms | Mediastinal Neoplasms | Germ Cell Neoplasms | Non Seminomatous Germ Cell Tumors

United States
IRCCS San Raffaele

Active, not recruiting

CNS Involvement in Primary Mediastinal Large B-Cell Lymphoma (PMLBCL)

Primary Mediastinal Large B-cell Lymphoma (PMBCL)
Taizhou HoudeAoke Biomedical Co., Ltd.

Not yet recruiting

Study of LP002 for the Treatment of Patients With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma

Primary Mediastinal Large B-Cell Lymphoma (PMBCL)

China
Fondazione Italiana Linfomi - ETS

Active, not recruiting

Primary Mediastinal Large B-cell Lymphoma (PMBCL): Multicenter Retrospective Study

Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Italy
Emilia Nozawa, PT PhD
University of Sao Paulo

Completed

Physiotherapy Exercises in Patients With Sternal Instability After Cardiovascular Surgery

Coronary Artery Disease | Cardiovascular Infections | Mediastinitis
Instituto Ecuatoriano de Enfermedades Digestivas

Recruiting

Endoscopic Ultrasound (EUS) Artificial Intelligence Model for Normal Mediastinal and Abdominal Strictures Assessment

Abdomen | Mediastinum | Anatomic Abnormality | Strictures

Ecuador
International Extranodal Lymphoma Study Group (IELSG)

Completed

A Clinico-Pathologic Study of Primary Mediastinal B-Cell Lymphoma

Primary Mediastinal B-Cell Lymphoma

Italy, United Kingdom, Switzerland, Spain
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Single Scope Staging of Lung Cancer With Endosonography (SCORE)

Non Small Cell Lung Cancer (NSCLC) | Indication Mediastinal Staging | Complete Endosonography

Netherlands, Belgium
Institut Bergonié

Completed

Feasibility Study on the Contribution of Guided Puncture With Echoendoscopy (APOGEE)

Hypermetabolic Lymphadenopathy Mediastinum Lower, Posterior and Middle, Detected by PET-CT With 18F-FDG (PET)

France
Merck Sharp & Dohme LLC

Terminated

Efficacy, Immunogenicity, and Safety of a Single Dose of V710 in Adult Patients Scheduled for Cardiothoracic Surgery (V710-003 AM2)

Bacteremia | Staphylococcus Aureus | Mediastinitis
Centre Henri Becquerel

Recruiting

Circulating Tumor DNA in Primary Mediastinal Large B-cell Lymphoma (PMBL) (CAMIL)

Primary Mediastinal Large B-cell Lymphoma

France
Royal Brompton & Harefield NHS Foundation Trust
Heidelberg University; Chelsea and Westminster NHS Foundation Trust

Withdrawn

EBUS-TBNA Versus EBUS-TBNB

Lymphoma | Carcinoma | Sarcoidosis | Mediastinal Lymphadenopathy | Hilar Lymphadenopathy | Mycobacterial Disease

United Kingdom, Germany
Ruijin Hospital

Recruiting

Zanubrutinib Combined With Tislelizumab in the Treatment of r/r PMBCL and EBV+ DLBCL

Primary Mediastinal Large B Cell Lymphoma | EBV-Positive DLBCL, Nos

China
IRCCS San Raffaele

Recruiting

Primary Mediastinal Large B-cell Lymphoma With CNS Involvement

Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Italy
Nicola Goekbuget

Completed

Newly Diagnosed Mature B-ALL, Burkitt's Lymphoma and Other High-grade Lymphoma in Adults

Lymphoblastic Lymphoma | Burkitt's Lymphoma | Mediastinal Neoplasms | Burkitt's Leukemia | Large Cell Anaplastic Lymphoma

Germany
Fred Hutchinson Cancer Center
National Cancer Institute (NCI); AstraZeneca; Juno Therapeutics, Inc.; MedImmune...

Terminated

JCAR014 and Durvalumab in Treating Patients With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Recurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

United States
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Terminated

Study of TQB2450 Injection in Subjects With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma

Relapsed or Refractory Primary Mediastinal B-cell Lymphoma (rrPMBCL)

China
Ruijin Hospital

Recruiting

Simultaneous Integrated Boost for Mediastinal Lymph Node Recurrence After Radical Surgery of Esophageal Cancer

Esophageal Cancer | Salvage Radiotherapy | Dose-escalation | Mediastinal Lymph Node Recurrence

China
Merck Sharp & Dohme LLC

Active, not recruiting

A Study of Pembrolizumab (MK-3475) in Relapsed or Refractory Classical Hodgkin's Lymphoma (rrcHL) or Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-B68)

Hodgkin's Lymphoma | Primary Mediastinal Large B-cell Lymphoma (PMBCL)

Canada, United States, Brazil, Czechia, France, Italy, Poland, Russian Federation, South Africa, Turkey, Ukraine
Milton S. Hershey Medical Center

Terminated

Lidocaine Administration During Flexible Bronchoscopy and Endobronchial Ultrasound

Pneumonia | Mediastinal Lymphadenopathy | Bronchiectasis Adult | Chest--Diseases | Cancer, Lung | Bronchopulmonary Disease | Infiltrates

United States
Azienda Ospedaliero, Universitaria Ospedali Riuniti

Completed

Conventional Versus Ultrasound-guided Transbronchial Needle Aspiration for the Diagnosis of Hilar/Mediastinal Lymphadenopathies

Lymphoma | Lung Neoplasms | Sarcoidosis | Mediastinal Lymphadenopathy | Hilar Lymphadenopathy

Italy
Gilead Sciences

Withdrawn

Idelalisib With Rituximab, Ifosfamide, Carboplatin, Etoposide (RICE) in Children and Adolescents

Diffuse Large B-Cell Lymphoma | Mediastinal B-cell Lymphoma

Italy, Spain, France, Poland
Merck Sharp & Dohme LLC

Completed

Study of Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma or Relapsed or Refractory Richter Syndrome (MK-3475-170/KEYNOTE-170)

Richter Syndrome | Mediastinal Large B-cell Lymphoma
Samsung Medical Center

Completed

Pilot Study of Ruxolitinib in Relapsed or Refractory Hodgkin Lymphoma and Primary Mediastinal Large B-cell Lymphoma (JAK2)

Primary Mediastinal Large B-cell Lymphoma | Relapsed or Refractory Hodgkin Lymphoma

Korea, Republic of
Chang Gung Memorial Hospital

Not yet recruiting

Lymphoma Patients Undergoing Mediastinal Radiotherapy in the Era of Modern Chemoradiation

Hodgkin Lymphoma | Non Hodgkin Lymphoma | Mediastinal Lymphoma

Taiwan

Clinical Trials on Mediastinal Diseases

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