Clinical Trials on Mendelian Susceptibility to Mycobacterial Disease

Total 3746 results

National Institute of Allergy and Infectious Diseases...

Completed

A Phase II/III Trial of Rifampin, Ciprofloxacin, Clofazimine, Ethambutol, and Amikacin in the Treatment of Disseminated Mycobacterium Avium Infection in HIV-Infected Individuals.

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pfizer

Completed

A Randomized, Double-Blind, Comparative Study of Azithromycin Versus Clarithromycin in Combination With Ethambutol for the Treatment of Disseminated Mycobacterium Avium Complex (MAC) Infection in AIDs Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pfizer

Completed

A Study of Azithromycin in the Prevention of Mycobacterium Avium Complex Disease (MAC) in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Cliniques universitaires Saint-Luc- Université...

Recruiting

Validation of the French ATI Scale and Predisposition to Use Technological Tools in Rehabilitation.

Stroke

Belgium
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Tanzania
Abbott

Completed

The Safety and Effectiveness of Clarithromycin Plus Ethambutol Used With or Without Clofazimine in the Treatment of MAC in Patients With AIDS

HIV Infections | Mycobacterium Avium-intracellular Infection

United States, Puerto Rico
Abbott
National Cancer Institute (NCI)

Completed

The Safety and Effectiveness of Clarithromycin Plus Zidovudine or Dideoxyinosine in the Treatment of Mycobacterium Avium Complex (MAC) Infections in Children With AIDS

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
University of California, San Francisco

Completed

A Randomized Controlled Prophylactic Study of Clofazimine To Prevent Mycobacterium Avium Complex Infection in HIV Disease

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pfizer

Completed

An Open-Label Study of the Use of Azithromycin in Patients With Symptomatic Disseminated Mycobacterium Avium-Intracellulare Complex (MAC) Infection Failing Current Therapy

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pfizer

Completed

A Randomized Study of Daily and Intermittent Prophylactic Regimens for the Prevention of Disseminated Mycobacterium Avium Complex (MAC) and Fungal Infections in HIV-Infected Patients

HIV Infections | Mycoses | Mycobacterium Avium-Intracellulare Infection

United States
Research Center Borstel
Ludwig-Maximilians - University of Munich

Terminated

PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis

Bacterial Infections | Tuberculosis, Pulmonary | Tuberculosis, Multidrug-Resistant | Mycobacterial Infection

Germany, Moldova, Republic of, Romania, Ukraine
National Institute of Allergy and Infectious Diseases...

Completed

A Randomized, Double-Blinded, Placebo-Controlled, Phase II Inhaled Interferon Gamma-1b and Antimycobacterials to Treat Pulmonary Mycobacterium Avium Complex Infections

Mycobacterium Avium-Intracellulare Infection

United States
University Ghent
University Hospital, Ghent

Completed

Trunkstability: a Predisposition for Armfunction

Trunk Stability

Belgium
Amgen

Completed

Evaluation of the Therapeutic Benefit of r-metHuIFN- Gamma in AIDS Patients With Disseminated Mycobacterium Avium-Intracellulare (MAI) Infection: A Multi-Centered Pilot Study

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Janssen Pharmaceutical K.K.

Recruiting

A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)

Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)

Taiwan, Korea, Republic of, Japan
Centre Hospitalier Universitaire, Amiens

Recruiting

CLArithromycin Versus AZIthromycin in the Treatment of Mycobacterium Avium Complex (MAC) Lung Infections (CLAZI)

Mycobacterium Avium Complex | Lung Infection

France
Johns Hopkins University

Recruiting

A Study of Standard Drugs for Mycobacterium Avium Complex

Mycobacterium Avium Complex

United States
National Jewish Health

Completed

Phase II Study of Amithiozone (Thiacetazone) for Patients With Mycobacterium Avium Complex Pulmonary Disease

Mycobacterium Avium-intracellulare Infection
Mayo Clinic

Completed

Mycobacterium Avium Intracellulare Complex (MAC) Study (MAC)

Mycobacterium Avium Intracellulare Complex (MAC)

United States
RedHill Biopharma Limited

Active, not recruiting

RHB-204 for the Treatment of Pulmonary Mycobacterium Avium Complex Disease (CleaR-MAC)

Lung Diseases | Bronchiectasis | Pulmonary Mycobacterium Avium Complex Infection

United States
Agouron Pharmaceuticals

Completed

A Study of Viracept in AIDS Patients With Mycobacterium Avium Complex Disease (MAC)

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Samsung Medical Center

Withdrawn

Inhaled Amikacin Treatment for Nontuberculous Mycobacterial Lung Disease

Pulmonary Non-tuberculous Mycobacterial Lung Disease

Korea, Republic of
Rutgers, The State University of New Jersey
National Institute of Neurological Disorders and Stroke (NINDS); National Institutes...

Recruiting

Parkinson Disease and DBS: Cognitive Effects in GBA Mutation Carriers

Parkinson Disease | Cognitive Decline | Parkinson | Genetic Predisposition | GBA Gene Mutation

United States
Chang Gung Memorial Hospital

Completed

Replacement of Lamivudine by Telbivudine to Improve Renal Function

Virus Diseases | Disorder Related to Transplantation | Injury Due to Exposure to External Cause
Upendra Devokta Memorial National Institute of...

Completed

Susceptibility Weighted Imaging for Detection of Thrombus in Acute Ischemic Stroke.

Acute Ischemic Stroke

Nepal
Radboud University Medical Center

Recruiting

A Prospective, Multicenter, Single-arm MAC-PD Cohort: a NTM-NET and ESGMYC Collaborative Study (MAC-PD cohort)

Mycobacterium Avium Complex Pulmonary Disease

Korea, Republic of, United States, Croatia, Japan, Netherlands
Anderson Clinical Research
Hoechst Marion Roussel

Completed

Tolerance, Safety, and Activity of Rifapentine Alone and in Combination Therapy in AIDS Patients With Mycobacterium Avium Complex Bacteremia.

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States, Canada
University of Florida

Withdrawn

Improving Tolerance of Treatment of Pulmonary MAC Infections (ITT-MAC)

Adverse Effects | Mycobacterium Avium Complex
King's College Hospital NHS Trust
University of Pennsylvania; Gilead Sciences; The Leeds Teaching Hospitals NHS... and other collaborators

Active, not recruiting

Genetic Determinants of Kidney Disease in People of African Ancestry With HIV (GEN-AFRICA)

Cardiovascular Diseases | Kidney Diseases | Obesity | Diabetes Mellitus | Genetic Predisposition to Disease | Kidney Injury | HIV Nephropathy

United Kingdom
National Taiwan University Hospital

Completed

Program Cell Death Receptor 1 in Mycobacterium Avium Complex Lung Disease

Mycobacterium Avium

Taiwan
National Institute of Allergy and Infectious Diseases...

Completed

The Safety and Effectiveness of Rifabutin, Combined With Clarithromycin or Azithromycin, in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Assistance Publique - Hôpitaux de Paris

Completed

Capacity Assessment in Persons With Alzheimer's Disease (MACAP)

Alzheimer's Disease | Capacity to Consent to Treatment | Capacity to Vote | Capacity to Design a Proxy

France
Pharmacia

Completed

A Double-Blind Randomized Clinical Trial of a Rifabutin Regimen in the Treatment of Mycobacterium-Avium Complex (MAC) Bacteremia in Patients With AIDS

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in AIDS Patients With CD4 Counts = or < 200: A Double-Blind, Placebo-Controlled Trial

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pharmacia

Completed

Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in HIV Positive Patients With CD4 Counts = or < 200: Treatment IND Study

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
Pharmacia

Completed

A Study of Rifabutin, Used Alone or With Ethambutol in the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in Patients With AIDS

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Institut Claudius Regaud

Recruiting

Study of Families With an Hemopathies Predisposition Related to the DDX41 Gene. (LUCID)

DDX41 Gene Mutation

France
National Institute of Allergy and Infectious Diseases...

Completed

Evaluation of Treatment for Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...
Abbott

Completed

A Phase II Safety and Efficacy Study of Clarithromycin in the Treatment of Disseminated M. Avium Complex (MAC) Infections in Patients With AIDS

HIV Infections | Mycobacterium Avium-intracellulare Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effects of Treatment for Mycobacterium Avium Complex (MAC) on the Cells of HIV-Infected Patients

HIV Infections | Mycobacterium Avium-Intracellulare Infection

United States
Afyonkarahisar Health Sciences University

Enrolling by invitation

Embolism in COVID-19 Positive Patients

Embolism | COVID-19 Pneumonia | Genetic Predisposition

Turkey
Hong Kong Sanatorium & Hospital
Chinese University of Hong Kong

Terminated

Pilot Study on Traditional Chinese Medicine and Food Allergy (TCMFA)

Allergy to Fish | Allergy to Shrimp | Allergy to Crab

Hong Kong
The University of Texas Health Science Center at...
Pfizer

Completed

Azithromycin in the Treatment of M. Avium Complex Lung Disease

Mycobacterium Avium Complex Lung Disease

United States
The University of Texas Health Science Center at...
Pfizer; Abbott

Completed

Use of Clarithromycin and Rifabutin for the Treatment of M. Avium Complex (MAC) Lung Disease

Mycobacterium Avium Complex Lung Disease

United States
Assistance Publique - Hôpitaux de Paris

Completed

Bone Resistant Tuberculosis (TboneR)

Bone and Osteoarticular Infection Due to MDR M. Tuberculosis Strains

France
Abramson Cancer Center at Penn Medicine
Fox Chase Cancer Center; Merck Sharp & Dohme LLC; AstraZeneca; Basser Center for...

Recruiting

Study of an eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Metastatic Cancer Patients (eReach)

Cancer

United States
Pfizer

Completed

A Study to Evaluate the Safety and Efficacy of Azithromycin in Individual Patients With Serious Nontuberculous Mycobacterial Disease Who Are Failing or Intolerant of Other Available Therapy

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States
Aaron Diamond AIDS Research Center

Completed

Placebo-Controlled Trial of Safety and Efficacy of Thalidomide in Patients With Infections Due to Mycobacterium and/or HIV

HIV Infections | Mycobacterium Avium-Intracellulare Infection | Tuberculosis, Mycobacterium Infection

United States

Clinical Trials on Mendelian Susceptibility to Mycobacterial Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Cambodia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations