Clinical Trials on Meningeal Melanomatosis

Total 329 results

Central Hospital, Nancy, France

Recruiting

Clinical, Radiological, Histologic and Molecular Features of a Cohort of Melanocytic Tumors of the Central Nervous System (MelaMen)

Meningeal Melanocytoma | Meningeal Melanomatosis | Meningeal Melanocytosis | Meningeal Melanoma

France
Baylor College of Medicine
GlaxoSmithKline

Completed

Phase 1 Intrathecal Topotecan for Neoplastic Meningitis (PBTC-019)

Neoplastic Meningitis

United States
M.D. Anderson Cancer Center
Schering-Plough; Enzon Pharmaceuticals, Inc.

Terminated

DepoCyt Plus Temozolomide in Patients With Neoplastic Meningitis

Neoplastic Meningitis

United States
Baylor College of Medicine

Completed

Intrathecal Mafosfamide

Malignant Meningeal Neoplasms

United States
M.D. Anderson Cancer Center
Genentech, Inc.

Completed

A Pilot Study of Bevacizumab for Neoplastic Meningitis

Neoplastic Meningitis

United States
Baylor College of Medicine
National Cancer Institute (NCI); Mayo Clinic; University of Pittsburgh; Brown University and other collaborators

Terminated

Intrathecal Gemcitabine to Treat Neoplastic Meningitis, IT Gemcitabine

Neoplasms | Meningitis

United States
Hui Bu

Unknown

Different Dose of Methotrexate for the Treatment of Meningeal Carcinomatosis

Meningeal Carcinomatosis
National Cancer Institute (NCI)

Completed

Phase I Study of Intrathecal Mafosfamide

Lymphoma | Leukemia | Meningeal Neoplasm

United States
National Cancer Institute (NCI)

Completed

Effect of Solar-Simulated Ultraviolet Radiation on Gene Expression in Unprotected and Sunscreen-Protected Skin of Healthy Adults With Fitzpatrick Skin Type II

Precancerous Condition | Non-melanomatous Skin Cancer

United States
University of Aarhus

Recruiting

Proton Cranio-spinal Irradiation for Leptomeningeal Metastasis (CSI ProLong)

Leptomeningeal Metastasis

Denmark
Dartmouth-Hitchcock Medical Center

Completed

Circulating Tumor DNA in Cerebrospinal Fluid as an Early Biomarker of Leptomeningeal Metastasis (LM)

Leptomeningeal Metastasis

United States
Cancer Institute and Hospital, Chinese Academy...

Completed

Tomotherapy for Leptomeningeal Metastases

Leptomeningeal Metastasis

China
Roswell Park Cancer Institute

Completed

Photodynamic Therapy in Treating Patients With Skin Cancer

Non-melanomatous Skin Cancer

United States
Plus Therapeutics

Recruiting

Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases (ReSPECT-LM)

Leptomeningeal Metastasis

United States
The First Hospital of Jilin University

Completed

Concurrent Involved-field Radiotherapy and Intrathecal Chemotherapy for Leptomeningeal Metastases From Solid Tumors

Leptomeningeal Metastasis

China
The First Hospital of Jilin University
The Second Hospital of Hebei Medical University; Second Affiliated Hospital... and other collaborators

Active, not recruiting

Intrathecal Pemetrexed for Leptomeningeal Metastasis

Leptomeningeal Metastases

China
Memorial Sloan Kettering Cancer Center
Fred Hutchinson Cancer Center

Active, not recruiting

Proton Craniospinal Radiation Therapy vs. Partial Photon Radiation Therapy for Leptomeningeal Metastasis From Solid Tumors

Leptomeningeal Metastases

United States
H. Lee Moffitt Cancer Center and Research Institute
Bayer

Terminated

Depocyt® With Sorafenib in Neoplastic Meningitis

Neoplastic Meningitis

United States
Y-mAbs Therapeutics

Withdrawn

177Lu-DTPA-Omburtamab Radioimmunotherapy for Leptomeningeal Metastasis From Solid Tumors (Breast, NSCLC, Malignant Melanoma)

Solid Tumor, Adult | Leptomeningeal Metastasis

United States, United Kingdom
Pacira Pharmaceuticals, Inc

Completed

DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor

Meningeal Neoplasms

United States, Canada
The First Hospital of Jilin University
The Second Hospital of Hebei Medical University; Second Affiliated Hospital... and other collaborators

Recruiting

Intra-pemetrexed Alone or Combined With Concurrent Radiotherapy for Leptomeningeal Metastasis

Leptomeningeal Metastasis

China
The First Hospital of Jilin University

Completed

Concurrent Intrathecal-pemetrexed and Involved-field Radiotherapy for Leptomeningeal Metastasis From Solid Tumors

Leptomeningeal Metastasis

China
West China Hospital

Not yet recruiting

Immune Checkpoint Inhibitors Intrathecal Injection in Patients With Leptomeningeal Metastases in NSCLC

NSCLC Associated With Leptomeningeal Metastases
Massachusetts General Hospital
Merck Sharp & Dohme LLC

Terminated

Pembrolizumab And Lenvatinib In Leptomeningeal Metastases

Solid Tumor | Solid Tumor, Adult | Leptomeningeal Metastasis

United States
University of Zurich
M.D. Anderson Cancer Center; The Netherlands Cancer Institute

Recruiting

Standardized Clinical Assessment of Patients With Leptomeningeal Metastasis (NANO-LM)

Leptomeningeal Disease | Leptomeningeal Metastasis | Leptomeningeal Neoplasms | Leptomeningeal Cancer

United States, Switzerland, Netherlands
Memorial Sloan Kettering Cancer Center
Center for Experimental Therapeutics; F.M. KIRBY FOUNDATION

Recruiting

A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis

Leptomeningeal Metastases

United States
Memorial Sloan Kettering Cancer Center

Completed

Study of Proton Radiation to the Brain and Spinal Cord for Patients With Leptomeningeal Metastases

Leptomeningeal Metastases

United States
Reata, a wholly owned subsidiary of Biogen

Terminated

A Safety Study of RTA 744 in Recurrent, Progressive or Refractory Neoplastic Meningitis (LMD)

Leptomeningeal Carcinomatosis

United States
The Cleveland Clinic
National Cancer Institute (NCI)

Terminated

Topical Aminolevulinic Acid in Patients With Nonmelanoma Skin Cancer

Non-melanomatous Skin Cancer
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Photodynamic Therapy in Treating Patients With Basal Cell Skin Cancer

Non-melanomatous Skin Cancer

United States
Baylor College of Medicine
National Cancer Institute (NCI)

Unknown

Low Fat Diet to Prevent Disease Progression in Patients With Skin Cancer

Non-Melanomatous Skin Cancer

United States
The First Hospital of Jilin University

Completed

Intrathecal Pemetrexed for Recurrent Leptomeningeal Metastases From Non-small Cell Lung Cancer

Leptomeningeal Metastases

China
Frank Meyskens
National Cancer Institute (NCI)

Terminated

Green Tea Extract in Treating Patients With Actinic Keratosis

Non-melanomatous Skin Cancer

United States
Second Affiliated Hospital of Nanchang University
Jiangsu Hansoh Pharmaceutical Co., Ltd.

Not yet recruiting

Almonertinib With Bevacizumab for EGFR-Mutant NSCLC Patients With Leptomeningeal Metastasis (ATTRACT)

NSCLC | EGFR Activating Mutation | Leptomeningeal Metastasis

China
Massachusetts General Hospital
Bristol-Myers Squibb

Completed

Ipilimumab and Nivolumab in Leptomeningeal Metastases

Leptomeningeal Carcinomatosis

United States
Guangzhou Medical University

Recruiting

Intra-pemetrexed Plus Third-generation Small Molecule TKI Drugs (e.g. 'Osimertinib') Versus Third-generation Small Molecule TKI Drugs Alone for Leptomeningeal Metastasis From Epidermal Growth Factor Receptor Mutation-Positive Non-Small-cell Lung Cancer

Leptomeningeal Metastasis

China
University of Wisconsin, Madison
National Cancer Institute (NCI)

Completed

Eflornithine to Prevent Skin Cancer in Patients With Previously Treated Early Stage Skin Cancer

Non-melanomatous Skin Cancer
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Acitretin in Preventing Skin Cancers in Patients With Previously Treated Skin Cancers Who Have Undergone Organ Transplantation

Non-melanomatous Skin Cancer

United States
Queen's Medical Center

Completed

Topical Imiquimod Compared With Surgery in Treating Patients With Basal Cell Skin Cancer

Non-melanomatous Skin Cancer

United Kingdom
National Naval Medical Center

Completed

Imiquimod Cream in Treating Patients With Basal Cell Skin Cancer

Non-melanomatous Skin Cancer

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Acitretin in Preventing Skin Cancer in Patients at High Risk for Skin Cancer

Non-melanomatous Skin Cancer
Hui Bu

Not yet recruiting

Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis

Leptomeningeal Metastasis | Durvalumab
The Netherlands Cancer Institute

Unknown

Clinical and Pharmacological Study With 2B3-101 in Patients With Breast Cancer and Leptomeningeal Metastases

Meningeal Carcinomatosis

Netherlands
Hebei Medical University

Recruiting

Clinical Observation of ICI Combined With Recombinant Human Endostatin on Leptomeningeal Metastasis of Lung Cancer

Leptomeningeal Metastasis | Immune Checkpoint Inhibitor | Endostatin

China
Institut Curie
Centre Leon Berard; Institut Bergonié; Hoffmann-La Roche; University Hospital,... and other collaborators

Completed

Intrathecal Trastuzumab Administration in Metastatic Breast Cancer Patients Developing Carcinomatous Meningitis (HIT)

Metastatic Breast Cancer | Carcinomatous Meningitis

France
Centre Oscar Lambret

Completed

Interest of Intrathecal Chemotherapy With Liposomal Cytarabine (DepoCyte®) in Meningeal Metastasis of Breast Cancer (DEPOSEIN)

Breast Cancer | Leptomeningeal Metastases

France
Laser and Skin Surgery Center of New York

Unknown

Photodynamic Therapy Using Aminolevulinic Acid in Treating Patients With Skin Cancer

Non-melanomatous Skin Cancer

United States
National Cancer Institute (NCI)

Withdrawn

Celecoxib in Preventing Skin Cancer

Non-melanomatous Skin Cancer

United States
University Hospital Tuebingen

Recruiting

Non Interventional German Leptomeningeal Disease Register

Meningeal Neoplasms | Leptomeningeal Disease

Germany
University of Virginia

Terminated

BATs in Patients With Breast Cancer and Leptomeningeal Metastases

Breast Cancer Female | Leptomeningeal Metastases

United States

Clinical Trials on Meningeal Melanomatosis

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