Clinical Trials on Mesothelioma, Malignant

Total 4504 results

Chinese PLA General Hospital

Unknown

Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso

Pancreatic Cancer | Malignant Mesothelioma | Triple Negative Breast Cancer | Endometrial Cancer | Ovarian Tumor | Other Mesothelin Positive Tumors

China
Checkpoint Therapeutics, Inc.
Novotech (Australia) Pty Limited

Recruiting

Phase 1 Study of CK-301 (Cosibelimab) as a Single Agent in Subjects With Advanced Cancers

Melanoma | Renal Cell Carcinoma | Head and Neck Cancer | Carcinoma, Non-Small-Cell Lung | Lung Neoplasms | Non Hodgkin Lymphoma | Endometrial Cancer | Carcinoma, Small Cell | Urothelial Carcinoma | Classical Hodgkin Lymphoma | Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma | Malignant Mesothelioma, Advanced

Australia, New Zealand, Thailand, Ukraine, Spain, Russian Federation, France, Poland, South Africa
Rijnstate Hospital

Terminated

N-AcetylCysteine vs. Placebo to Prevent Neurotoxicity Induced by Platinum Containing Chemotherapy (NAC-PNP)

Carcinoma, Non-Small-Cell Lung | Mesothelioma | Carcinoma, Small Cell Lung

Netherlands
Kyowa Kirin Korea Co., Ltd.

Terminated

Two-Part, Open-Label, Multi-Center, Phase 1/2 Study of BIW-8962 as Monotherapy in Subjects With Lung Cancer

Phase 1 Portion : Non Small Cell Lung Cancer(NSCLC), Small Cell Lung Cancer(SCLC), Mesothelioma | Phase 2 Portion : Small Cell Lung Cancer(SCLC)

Korea, Republic of
MaxCyte, Inc.
CTI Clinical Trial and Consulting Services

Terminated

Intraperitoneal MCY-M11 (Mesothelin-targeting CAR) for Treatment of Advanced Ovarian Cancer and Peritoneal Mesothelioma

Fallopian Tube Adenocarcinoma | Peritoneal Mesothelioma | Primary Peritoneal Carcinoma | Adenocarcinoma of the Ovary

United States
University Hospital, Antwerp

Completed

Dendritic Cell Vaccination for Patients With Solid Tumors

Renal Cell Carcinoma | Glioblastoma | Malignant Mesothelioma | Colorectal Tumors | Breast Cancers | Sarcomas

Belgium
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Printed Education Materials in Patients Who Are Finishing Treatment for Stage I, Stage II, or Stage IIIA Breast Cancer, Colorectal Cancer, Prostate Cancer, or Chest Cancer

Breast Cancer | Colorectal Cancer | Lung Cancer | Prostate Cancer | Malignant Mesothelioma | Psychosocial Effects of Cancer and Its Treatment | Thymoma and Thymic Carcinoma

United States
Memorial Sloan Kettering Cancer Center
Genelux Corporation

Active, not recruiting

Intra-pleural Administration of GL-ONC1, a Genetically Modified Vaccinia Virus, in Patients With Malignant Pleural Effusion: Primary, Metastases and Mesothelioma

Lung Cancer

United States
National Cancer Institute (NCI)

Recruiting

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

Mesothelioma | Familial Cancer | BRCA1-Associated Protein-1 (BAP1) Mutations | Tumor Predisposition Syndrome (TPDS)

United States
National Cancer Institute (NCI)

Recruiting

Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies

Ovarian Cancer | Gastrointestinal Cancer | Peritoneal Carcinomatosis | Peritoneal Mesothelioma | Appendiceal Cancer

United States
National Cancer Institute (NCI)

Terminated

Depsipeptide/Flavopiridol Infusion for Cancers of the Lungs, Esophagus, Pleura, Thymus or Mediastinum

Carcinoma, Non-Small-Cell Lung | Esophageal Neoplasms | Mesothelioma | Carcinoma, Small Cell

United States
Memorial Sloan Kettering Cancer Center
United States Department of Defense; Bellicum Pharmaceuticals

Active, not recruiting

Malignant Pleural Disease Treated With Autologous T Cells Genetically Engineered to Target the Cancer-Cell Surface Antigen Mesothelin

Breast Cancer | Lung Cancer | Mesothelioma | Metastases | Malignant Pleural Disease

United States
National Cancer Institute (NCI)

Completed

SS1P and Pentostatin Plus Cyclophosphamide for Mesothelioma

Pancreatic Neoplasms | Mesothelioma | Adenocarcinoma of Lung

United States
Ottawa Regional Cancer Centre

Completed

Combination Chemotherapy and Tamoxifen in Treating Patients With Solid Tumors

Sarcoma | Head and Neck Cancer | Brain and Central Nervous System Tumors | Malignant Mesothelioma | Liver Cancer | Pheochromocytoma | Adrenocortical Carcinoma

Canada
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Using a Targeted Cancer Vaccine (Galinpepimut-S) With Immunotherapy (Nivolumab) in Mesothelioma

Mesothelioma | Wilms Tumor | Pleural Mesothelioma

United States
University of Pennsylvania

Completed

CART-meso in Mesothelin Expressing Cancers

Epithelial Ovarian Cancer | Metastatic Pancreatic (Ductal) Adenocarcinoma | Malignant Epithelial Pleural Mesothelioma

United States
UTC Therapeutics Inc.
Peking University Cancer Hospital & Institute

Recruiting

Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors

Colorectal Cancer | Pancreatic Cancer | Rectal Cancer | Malignant Mesothelioma | Bile Duct Cancer | Breast Cancer Female | Ovary Cancer

China
Hospices Civils de Lyon

Unknown

French National Registry of Rare Peritoneal Surface Malignancies (RENAPE)

Pseudomyxoma Peritonei | Peritoneal Mesothelioma | Desmoplastic Small Round Cell Tumor | Rare Peritoneal Surface Malignancies | Psammocarcinoma | Primary Peritoneal Serous Carcinoma | Diffuse Peritoneal Leiomyomatosis | Appendiceal Mucinous Neoplasms

France
National Cancer Institute (NCI)

Completed

Immunotoxin Therapy in Treating Patients With Advanced Cancer

Cervical Cancer | Head and Neck Cancer | Pancreatic Cancer | Ovarian Cancer | Fallopian Tube Cancer | Lung Cancer | Malignant Mesothelioma | Primary Peritoneal Cavity Cancer

United States
Candel Therapeutics, Inc.
University of Pennsylvania

Completed

Intrapleural AdV-tk Therapy in Patients With Malignant Pleural Effusion (MpeTK01)

Breast Cancer | Ovarian Cancer | Lung Cancer | Mesothelioma | Malignant Pleural Effusion

United States
Massachusetts General Hospital

Active, not recruiting

The Transitions Project: Supporting Adults During the Shift From Cancer Treatment to Surveillance

Non Small Cell Lung Cancer | Mesothelioma | Small-cell Lung Cancer | Cognitive Behavioral Therapy

United States
National Cancer Institute (NCI)

Completed

Immunotoxin Therapy in Treating Patients With Advanced Solid Tumors

Cervical Cancer | Head and Neck Cancer | Pancreatic Cancer | Ovarian Cancer | Fallopian Tube Cancer | Lung Cancer | Malignant Mesothelioma | Primary Peritoneal Cavity Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Study of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma

Advanced Renal Cell Carcinoma | Advanced Mesothelioma | Advanced Osteosarcoma

United States
University of Illinois at Chicago
Millennium Pharmaceuticals, Inc.

Completed

Phase I Study of MLN8237 and Pazopanib in Patients With Solid Tumors

Melanoma | Head and Neck Neoplasms | Malignant Neoplasm of Breast | Malignant Neoplasm of Thorax | CNS Malignancy | Malignant Neoplasm of Gastrointestinal Tract | Genitourinary Neoplasms Malignancy and Gender Unspecified

United States
National Cancer Institute (NCI)

Completed

Treatment of Peritoneal Cancer With Surgery, Perfused Heated Cisplatin and Chemotherapy

Mesothelioma | Abdominal Neoplasm | Colonic Neoplasm | Peritoneal Neoplasm

United States
University of Maryland, Baltimore
NovoCure Ltd.

Unknown

Dielectric Properties of Matched Tissue Samples From Thoracic Malignancies and Corresponding Normal Tissues

Esophageal Cancer | Lung Cancer | Mesothelioma; Lung
Aminex Therapeutics, Inc.

Recruiting

Oral AMXT 1501 Dicaprate in Combination With IV DFMO

Melanoma | Cervical Cancer | Cancer | Breast Cancer | Head and Neck Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Solid Tumor | Endometrial Cancer | Advanced Cancer | Diffuse Midline Glioma, H3 K27M-Mutant | Papillary Thyroid Cancer | Solid Carcinoma | Mesotheliomas Pleural | Glioma, Malignant | Ovary Cancer and other conditions

United States, Australia
National Cancer Institute (NCI)

Active, not recruiting

Testing the Sequential Combination of the Anti-cancer Drugs Olaparib Followed by Adavosertib (AZD1775) in Patients With Advanced Solid Tumors With Selected Mutations and PARP Resistance, STAR Study

Advanced Malignant Solid Neoplasm | Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Translational Research in Oncology
Bayer; Novartis

Withdrawn

Regorafenib With Tislelizumab in Patients With Selected Mismatch Repair-Proficient/Microsatellite Stable Cancers (REFIT-MSS)

Soft Tissue Sarcoma | Small Cell Lung Carcinoma | Colorectal Neoplasms | Anal Squamous Cell Carcinoma | Malignant Pleural Mesothelioma | Castrate Resistant Prostate Cancer | Gastroenteropancreatic Neuroendocrine Neoplasm | Neuroendocrine Carcinoma of Prostate
Centre Hospitalier Universitaire de Nice

Completed

The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural Mesothelioma

Pneumothorax | Mesothelioma | Pleural Neoplasms | Parathyroid Neoplasms | Benign Tumor of the Thyroid | Tumor of the Thyroid

France
TCR2 Therapeutics

Active, not recruiting

A Phase 1/2 Trial of TC-510 In Patients With Advanced Mesothelin-Expressing Cancer

Colorectal Neoplasms | Colorectal Cancer | Pancreatic Neoplasms | Pancreatic Cancer | Pancreatic Adenocarcinoma | Ovarian Neoplasms | Ovarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Mesothelioma, Malignant | Cholangiocarcinoma | Triple Negative Breast Cancer | Ovarian Adenocarcinoma | Mesotheliomas Pleural and other conditions

United States
Mayo Clinic

Recruiting

Staging Procedures to Diagnose Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
University of Pennsylvania
National Cancer Institute (NCI); Biogen

Completed

Gene Therapy for Pleural Malignancies

Pleural Mesothelioma | Metastatic Pleural Effusions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Videos and Questionnaires in Assessing Patient Perception of Physician's Compassion, Communication Skills, and Professionalism During Clinic Visits

Malignant Neoplasm | Metastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Locally Advanced Malignant Neoplasm

United States
Abramson Cancer Center of the University of Pennsylvania
National Cancer Institute (NCI)

Completed

Intrapleural BG00001 in Treating Patients With Malignant Pleural Mesothelioma or Malignant Pleural Effusions

Cancer

United States
Mayo Clinic

Recruiting

Chemotherapy Followed by Surgery and Neoadjuvant Hemothoracic Intensity Modified Radiation Therapy (IMRT) for Patients With Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and M1774 for Advanced Solid Tumors

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of the Anti-cancer Drugs Copanlisib, Olaparib, and MEDI4736 (Durvalumab) in Patients With Advanced Solid Tumors With Selected Mutations

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
National Cancer Institute (NCI)

Completed

Testing the Addition of the Anti-Cancer Drug Talazoparib to the Combination of Carboplatin and Paclitaxel for the Treatment of Advanced Cancer

Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Muscadine Grape Skin Extract in Treating Patients With Malignancy That Is Metastatic or Cannot Be Removed by Surgery

Metastatic Malignant Neoplasm | Unresectable Malignant Neoplasm | Advanced Malignant Neoplasm

United States
National Cancer Institute (NCI)

Completed

Mesothelin-Targeted Immunotoxin LMB-100 in Combination With Tofacitinib in Persons With Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and Other Mesothelin Expressing Solid Tumors

Epithelioid Mesothelioma | Cholangiocarcinoma, Extrahepatic | Neoplasms With Mesothelin Expression | Adenocarcinoma, Pancreatic

United States
Mayo Clinic

Recruiting

Surgery for Mesothelioma After Radiation Therapy "SMART" for Resectable Malignant Pleural Mesothelioma

Mesothelioma | Solitary Fibrous Tumor of the Pleura

United States
CSA Medical, Inc.
Reset Medical, Inc.

Withdrawn

CryoSpray Ablation(tm)Thoracic Patient Registry

Asthma | Emphysema | Lung Cancer | Mesothelioma | COPD | Sarcoidosis | Chronic Bronchitis
National Cancer Institute (NCI)

Recruiting

Study of Chemotherapy Plus Ipatasertib for People With Solid Tumors With AKT Mutations, A ComboMATCH Treatment Trial

Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States, Puerto Rico
University of California, San Francisco

Completed

Integrative Palliative Care/Psycho-Oncology Telehealth Intervention in Patients With Advanced Cancer

Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States
Prelude Therapeutics

Active, not recruiting

A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors

Sarcoma | Breast Cancer | Glioblastoma | Malignant Mesothelioma | Endometrial Cancer | Head and Neck Squamous Cell Carcinoma | Non-small Cell Lung Cancers

United States, Singapore
Rajni Agarwal

Completed

CD34+ Cell Enriched and T Cell Depleted Allogeneic Stem Cell Transplantation for Patients With Mismatched Related Donors or Borderline Organ Function

Malignant Diseases | Non-malignant Diseases

United States
A&G Pharmaceutical Inc.
University of Maryland Greenebaum Cancer Center

Recruiting

First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies

Non Small Cell Lung Cancer | Mesothelioma | Triple Negative Breast Cancer | Hormone-Resistant Breast Cancer

United States
National Cancer Institute (NCI)

Terminated

CAR T Cell Receptor Immunotherapy Targeting Mesothelin for Patients With Metastatic Cancer

Cervical Cancer | Pancreatic Cancer | Ovarian Cancer | Lung Cancer | Mesothelioma

United States
M.D. Anderson Cancer Center

Active, not recruiting

Avelumab and M6620 for the Treatment of DDR Deficient Metastatic or Unresectable Solid Tumors

Refractory Malignant Solid Neoplasm | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm

United States

Clinical Trials on Mesothelioma, Malignant

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