Clinical Trials on Metastases in Italy

Total 234 results

HUYABIO International, LLC.
Bristol-Myers Squibb

Recruiting

Study Comparing Investigational Drug HBI-8000 Combined With Nivolumab vs. Nivolumab in Patients With Advanced Melanoma

Unresectable or Metastatic Melanoma | Progressive Brain Metastasis

Spain, United States, Italy, Japan, Belgium, France, New Zealand, Brazil, Korea, Republic of, Australia, Germany, Singapore, Czechia, Austria, South Africa, United Kingdom, Puerto Rico
AstraZeneca
Daiichi Sankyo

Completed

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer (DESTINY-B12)

Breast Cancer

Denmark, Finland, Italy, Norway, Spain, Sweden, Poland, United States, Canada, Germany, Japan, Netherlands, Portugal, Switzerland, Australia, United Kingdom, Belgium, Ireland
Novartis Pharmaceuticals

Completed

Lapatinib for Brain Metastases In ErbB2-Positive Breast Cancer

Neoplasms, Breast

Spain, Canada, United States, Australia, Austria, Italy, Japan, Poland, Sweden, France, Germany, Switzerland, Taiwan, United Kingdom, Belgium, Greece, India
Istituto Scientifico Romagnolo per lo Studio e...

Recruiting

Radiometabolic Therapy With 177Lu PSMA in PSMA PET/CT Positive Advanced/Metastatic Tumours: (LUBASKET)

Cancer

Italy
Spectrum Pharmaceuticals, Inc

Completed

Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer (ENRICH)

Breast Cancer | Metastases

United States, Canada, France, Spain, United Kingdom, Austria, Argentina, Brazil, Chile, Croatia, Greece, Hungary, Italy, Lithuania, Peru
European Institute of Oncology

Recruiting

Circulating Tumor Cells (CTC) Before and After Thoracic Resection With and Without Intraoperative Use of ExtraCorporeal Membrane Oxygenator(ECMO) or Cardio Pulmonary By Pass (CPB)

Cardiopulmonary Bypass | Thoracic Surgery

Italy
Fondazione Poliambulanza Istituto Ospedaliero
The Queen Elizabeth Hospital; Clinica Universidad de Navarra, Pamplona, Spain; Amsterdam UMC location University of Amsterdam, Amsterdam, the Netherlands and other collaborators

Completed

Impact of Minimally Invasive and Open Liver Surgery in Different BMI-classes (MILSOBES)

Obesity | Liver Metastases | Liver Cancer

Italy
National Cancer Institute, Naples

Active, not recruiting

MAnagement of METastatic Disease In Campania (MAMETIC) (MAMETIC)

Metastatic Disease

Italy
European Organisation for Research and Treatment...
Institute of Cancer Research, United Kingdom; Arbeitsgruppe Lebermetastasen...

Terminated

Chemotherapy and Bevacizumab With or Without Radiofrequency Ablation in Treating Unresectable Liver Metastases in Patients With Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

Netherlands, United Kingdom, Belgium, France, Germany, Sweden, Hungary, Austria, Egypt, Italy
Matteo's Friends

Recruiting

Dynamic Changes in Circulating Tumour Cells Protein Expression (Liquid-DRER2)

Recurrence Free Survival

Italy
InSightec

Completed

ExAblate (MRgFUS) Treatment of Metastatic Bone Tumors for the Palliation of Pain

Multiple Myeloma | Bone Metastases

United States, Canada, Israel, Italy, Russian Federation
Pfizer

Completed

Study Tests The Safety And Effectiveness Of SU011248 In Patients With Non-Small Cell Lung Cancer Having Brain Metastases

Non-Small Cell Lung Cancer

United States, Spain, Italy, France
Bayer

Completed

Radium(223) Dichloride (Alpharadin) in Castration-Resistant (Hormone-Refractory) Prostate Cancer Patients With Bone Metastases

Prostatic Neoplasms

Belgium, Spain, Canada, France, Switzerland, Germany, United Kingdom, Denmark, Russian Federation, Sweden, Israel, Italy, Netherlands, Norway, Czech Republic, Finland, Poland, Ireland, Mexico
Sirtex Medical

Completed

FOLFOX Plus SIR-SPHERES MICROSPHERES Versus FOLFOX Alone in Patients With Liver Mets From Primary Colorectal Cancer (SIRFLOX)

Colorectal Cancer | Liver Metastases | Colorectal Carcinoma

United States, Israel, Australia, Belgium, New Zealand, Spain, Germany, Switzerland, Italy, France, Poland
Novartis Pharmaceuticals

Completed

Safety and Efficacy of Zoledronic Acid in Patients With Breast Cancer With Metastatic Bone Lesions

Breast Cancer With Bone Metastasis

Italy
University Ghent
University Hospital, Geneva

Active, not recruiting

PEACE V: Salvage Treatment of OligoRecurrent Nodal Prostate Cancer Metastases (STORM)

Prostate Cancer | Metastatic Cancer | Prostate Cancer Metastatic | Oligometastatic Cancer

Norway, Spain, Belgium, Switzerland, Australia, Italy
Regina Elena Cancer Institute
Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Weizmann Institute... and other collaborators

Recruiting

Observational Study of Viral BIOmarkers and microRNAs in Tumors Orofarynx and Occult Tumors Positive for Papilloma Virus

Liquid Biopsy | Squamous Cell Carcinoma of the Oropharynx | Lymph Node Metastasis | Carcinomas of Unknown Primary Site | High-risk Human Papillomavirus Infection | Occult Tumor of the Head and Neck Area

Italy
University of Bologna

Completed

Repeated EUS-guided Fine Needle Biopsy of Pancreatic Masses After Non-diagnostic or Inconclusive Results (REuBio)

Pancreatic Adenocarcinoma | Pancreas Cancer | Pancreas Metastases

Italy
Fondazione Policlinico Universitario Agostino Gemelli...

Completed

Is Desmoplastic Stromal Reaction Useful to Modulate Lymph Node Dissection in Sporadic Medullary Thyroid Carcinoma? (DSR-MTC)

Medullary Thyroid Cancer | Lymph Node Disease | Lymph Node Metastasis | Medullary Carcinoma | Medullary Tumor | Medullary Neoplasms | Desmoplasia | Desmoplastic | Desmoplastic Reaction

Italy
Bayer

Terminated

Colorectal Cancer Treated With Adjuvant Regorafenib Versus Placebo After Curative Treatment of Liver Metastases in a Randomized, Double-blind, Placebo-Controlled Phase-III STudy (COAST)

Colorectal Neoplasms

Belgium, France, Spain, China, United States, Canada, Germany, Portugal, Japan, Israel, United Kingdom, Italy, Australia, Brazil
University of Roma La Sapienza

Recruiting

Impact of ctDNA in Cancer Early Detection and STAS Evaluation in Patients With GGOs

Lung Cancer | Circulating Tumor Cell | Spreading of Tumor

Italy
Hoffmann-La Roche

Completed

A Study Evaluating the Safety and Efficacy of Cobimetinib Plus Atezolizumab in BRAFV600 Wild-type Melanoma With Central Nervous System Metastases and Cobimetinib Plus Atezolizumab and Vemurafenib in BRAFV600 Mutation-positive Melanoma With Central Nervous System Metastases

Metastatic Melanoma

France, Italy, Spain, Brazil, Latvia, Germany, Hungary, Switzerland
NovoCure GmbH

Active, not recruiting

Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC).

Brain Metastases From Non-small Cell Lung Cancer (NSCLC)

United States, China, Israel, Spain, Austria, Canada, Hong Kong, Germany, France, Bulgaria, Croatia, Hungary, Italy, Poland, Serbia
European Organisation for Research and Treatment...
Cancer Research UK; Australasian Gastro-Intestinal Trials Group; Arbeitsgruppe... and other collaborators

Unknown

Surgery With or Without Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer

Colorectal Cancer | Metastatic Cancer

France, United Kingdom, Australia, Sweden, Belgium, Netherlands, Germany, Austria, Hong Kong, Italy, New Zealand, Norway, Portugal
Quovadis Associazione
Neopharmed Gentili S.p.A.

Active, not recruiting

Mesoglycan (Prisma®) Versus Placebo in Secondary Prevention of the Superficial Venous Thrombosis

Superficial Venous Thrombosis of Leg, Secondary Prevention

Italy
Mario Negri Institute for Pharmacological Research

Completed

Paricalcitol in Reducing Parathyroid Hormone Levels and Ameliorating Markers of Bone Remodelling in Renal Transplant Recipients With Secondary Hyperparathyroidism (APPLE)

Renal Transplant | Secondary Hyperparathyroidism

Italy
HistoSonics, Inc.

Active, not recruiting

The HistoSonics System for Treatment of Primary and Metastatic Liver Tumors Using Histotripsy (#HOPE4LIVER EU/UK) (#HOPE4LIVER)

Liver Neoplasms | Hepatocellular Carcinoma | Liver Metastases

United Kingdom, Spain, Germany, Italy
Fondazione del Piemonte per l'Oncologia

Completed

A Study of Nab-paclitaxel-based Doublet as First Line Therapy in Patients With Cancer of Unknown Primary (CUP) (AGNOSTOS)

Unknown Primary Tumors

Italy
University of Trieste

Unknown

Avastin for CNV Secondary to Pattern Dystrophy

Choroidal Neovascularization Secondary to Pattern Dystrophy

Italy
Azienda Ospedaliera Città della Salute e della...

Completed

A Study to Investigate the Possible Causes of Secondary Effects During Use of Peripheral Midline Type Catheter in Patients Hospitalized in Different Care Settings (MIDES)

Upper Extremity Deep Vein Thrombosis, Secondary

Italy
University of Roma La Sapienza

Completed

Dual RElease Hydrocortisone Versus conventionAl Glucocorticoid replaceMent Therapy in Hypocortisolism (DREAM) (DREAM)

Secondary Adrenal Insufficiency | Primary Adrenal Insufficiency

Italy
Azienda Ospedaliero-Universitaria Consorziale Policlinico...

Completed

Detection and Clinical Significance of Circulating Cancer Cells in Patient Undergoing Radical Cystectomy (CirCanCell)

Bladder Cancer | Circulating Tumor Cells

Italy
Istituto Clinico Humanitas

Recruiting

SBRT Dose Escalation for Reirradiation of Inoperable Lung Lesions (STRILL)

Non Small Cell Lung Cancer | Lung Metastases

Italy
Istituto Ortopedico Rizzoli

Completed

Retrospective Case Series of COVID19+ Patients Undergoing Orthopedic Surgery (COVID19&SURG)

Coronavirus Infection | Bone Metastases | Orthopedic Disorder | Bone Neoplasm | Bone Fracture

Italy
IRCCS San Raffaele

Recruiting

EUS-guided PORtal Vein Sampling for Circulating Tumor Cells in Pancreatic Cancer Patients (EUPhORIC)

Pancreatic Cancer | Pancreatic Adenocarcinoma

Italy
Azienda Ospedaliera di Padova

Unknown

Pilot Study of Irreversible Electroporation (IRE) to Treat Metastatic Liver Cancer & Cholangiocarcinoma

Neoplasm Metastasis | Cholangiocarcinoma | Metastatic Liver Cancer

Italy
University of Padova
Istituto Oncologico Veneto IRCCS; Azienda Ulss 2 Marca Trevigiana; Associazione... and other collaborators

Recruiting

IMMUNOlogical Microenvironment in REctal Adenocarcinoma Treatment (IMMUNOREACT1)

Rectal Cancer Stage T1-T2 | Rectal Cancer Nodal Metastasis

Italy
Italian Trial in Medical Oncology

Completed

Study Comparing Association Between Sorafenib and Interleukin-2 (IL-2) Versus Sorafenib in 1st Line Therapy in Advanced (Adv) Renal Cell Carcinoma (RCC) (ROSORC)

Renal Cell Carcinoma | Metastatic Disease

Italy
Eli Lilly and Company

Completed

A Phase 3 Trial of ALIMTA (LY231514, Pemetrexed) Plus GEMZAR Versus GEMZAR in Patients With Unresectable or Metastatic Cancer of the Pancreas.

Pancreatic Neoplasms | Metastases, Neoplasm

United States, France, United Kingdom, Germany, Taiwan, Spain, Belgium, Portugal, Peru, Austria, Italy, Sweden, Netherlands, Venezuela, Argentina, Australia, Colombia, Greece
Bristol-Myers Squibb

Completed

MAD in Cancer Patients: Safety of BMS-582664 in Patients With Advanced or Metastatic Solid Tumors

Neoplasm Metastasis | Tumors

Italy, United Kingdom, United States, Canada
Novartis Pharmaceuticals

Completed

Safety of Everolimus in Combination Therapy, in Patients With HER2-overexpressing Metastatic Breast Cancer

Breast Neoplasms | Neoplasm Metastasis

Belgium, Italy, Poland, Sweden, France
Novartis Pharmaceuticals

Completed

A Study to Evaluate the Safety and Efficacy of Zoledronic Acid in the Prevention or Delaying of Bone Metastasis in Patients With Stage IIIA and IIIB Non-small Cell Lung Cancer (NSCLC)

Non-Small-Cell Lung Cancer

Greece, Taiwan, Germany, Belgium, Italy, Spain, United Kingdom, Korea, Republic of, Netherlands, China, Hungary, Poland, France, Thailand, Portugal
Maastricht University Medical Center
KU Leuven; University College, London; Erasmus Medical Center; Catholic University... and other collaborators

Active, not recruiting

IMMUNOtherapy and Stereotactic ABlative Radiotherapy (IMMUNOSABR) a Phase II Study (IMMUNOSABR2)

NSCLC Stage IV | Metastatic Disease

Netherlands, Belgium, United Kingdom, Germany, France, Italy
Gabriele Anania

Completed

Italian Study on the Right Hemicolectomy: How the Lymphadenectomy is Performed (CoDIG-2)

Colon Cancer | Surgical Procedure, Unspecified | Lymph Node Metastasis

Italy
Arcispedale Santa Maria Nuova-IRCCS

Completed

Feasibility of an Early Palliative Care Intervention for Metastatic Cancer Patients. A Phase 2 Study.

Gastric Cancer | Lung Cancer | Mesothelioma | Pancreas Cancer

Italy
Amgen
Daiichi Sankyo, Inc.

Completed

Denosumab Compared to Zoledronic Acid in the Treatment of Bone Disease in Patients With Multiple Myeloma

Cancer | Multiple Myeloma | Bone Metastases | Hematologic Malignancies | Oncology | Multiple Myeloma Bone Lesions

United States, Germany, Italy, Spain, Canada, France, Czechia, Hungary, Korea, Republic of, Russian Federation, United Kingdom, Taiwan, Australia, Hong Kong, New Zealand, Austria, Slovakia, Portugal, Greece, Bulgaria, Poland, Ukraine and more
NantCell, Inc.
Takeda

Terminated

QUILT-2.014: Gemcitabine and AMG 479 in Metastatic Adenocarcinoma of the Pancreas (GAMMA)

Cancer | Pancreatic Cancer | Advanced Solid Tumors | Metastatic Cancer | Bone Metastases | Solid Tumors | Pancreas Cancer | Adenocarcinoma of the Pancreas | Oncology | Cancer of Pancreas | Metastatic Pancreatic Cancer | Metastases | Cancer of the Pancreas | Advanced Malignancy | Oncology Patients | Endocrine Cancer

Italy, Spain, United Kingdom, Belgium, Canada, Denmark, Romania, United States, Germany, Netherlands, Korea, Republic of, Russian Federation, Australia, Austria, Lithuania, Portugal, Greece, Poland, Switzerland, Serbia, Bulgaria, ... and more
Francesco De Cobelli

Recruiting

Microwave Ablation for Treatment of Small Renal Tumors and Primary and Secondary Liver Neoplasms

Kidney Cancer | Renal Cell Carcinoma | Liver Cancer | Liver Metastasis Colon Cancer

Italy
Bayer

Completed

Radium-223 Dichloride Long-term Follow-up Program

Neoplasm Metastasis / Bone and Bones

Belgium, Spain, Taiwan, United States, Japan, Russian Federation, Canada, Finland, Korea, Republic of, Singapore, Australia, Germany, Israel, United Kingdom, Italy, France, Poland, Brazil, Czechia, Norway, Sweden, Hong Kong
University of Milano Bicocca
Humanitas Clinical and Research Center; Niguarda Hospital; Azienda Ospedaliero... and other collaborators

Recruiting

The Role Of Circulating Tumor Cells As Markers Of Advanced Disease And Prognosis In HCC

Hepatocellular Carcinoma | Circulating Tumor Cell | Recurrent Hepatocellular Carcinoma

Italy

Clinical Trials on Metastases in Italy

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritius

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations