Clinical Trials on Metastatic Neoplasm in Japan

Total 2652 results

National Hospital Organization Nagoya Medical Center
Merck Sharp & Dohme LLC; Central Japan Lung Study Group

Active, not recruiting

Pembrolizumab Plus Pemetrexed for Elderly Patients With Non-Sq NSCLC With PD-L1 < 50%: CJLSG1901

Non-squamous Non-small-cell Lung Cancer | Cancer, Lung

Japan
Kobe City General Hospital

Terminated

The Safety and Efficacy of Pemetrexed Rechallenge With Bevacizumab

Advanced Non-small Cell Lung Cancer

Japan
Osaka University
Ono Pharmaceutical Co. Ltd; Kyowa Kirin Co., Ltd.; Clinical Study Support, Inc.; Fiverings Co., Ltd...

Completed

Study of Pre-operative Combination Therapy With Mogamulizumab and Nivolumab Against Solid Cancer Patients

Gastric Cancer | Esophageal Cancer | Lung Cancer | Renal Cancer | Oral Cancer

Japan
Osaka Medical College

Completed

Primary Chemotherapy With Anthracycline Followed by Nab-paclitaxel and Trastuzumab

Breast Cancer | Effects of Chemotherapy | HER-2 Positive Breast Cancer

Japan
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Active, not recruiting

A Study of the Effectiveness and Safety of Nivolumab Plus Chemotherapy in Participants With Untreated Advanced/Recurrent Gastric Cancer (G-KNIGHT)

Stomach Neoplasms

Japan
Daiichi Sankyo Co., Ltd.
AstraZeneca

Completed

Phase 1 Study to Evaluate the Effect of DS-8201a on the QT/QTc Interval and Pharmacokinetics in HER2-Expressing Breast Cancer

Malignant Neoplasm of Breast

Japan
Daiichi Sankyo Co., Ltd.

Completed

Study of Quizartinib in Japanese Patients With Newly Diagnosed Acute Myeloid Leukemia (AML)

Acute Myeloid Leukemia

Japan
GlaxoSmithKline

Completed

Extension Study of the Efficacy of the GSK 580299 Vaccine in Japanese Women Vaccinated in the Primary NCT00316693 Study

Infections, Papillomavirus

Japan
Hokkaido University Hospital
Merck Sharp & Dohme LLC

Recruiting

Docetaxel/Pembrolizumab in Head and Neck Squamous Cell Carcinoma

Effect of Drug

Japan
Fukushima Medical University
Human Genome Center, Institute of Medical Science, University of Tokyo

Completed

Multiple-Vaccine Therapy in Treating Patients With Non-small Cell Lung Cancer

Non Small Cell Lung Cancer

Japan
Shoichi Fujii, MD, PhD

Unknown

Trial to Evaluate Laparoscopic Versus Open Surgery in Elderly Colorectal Cancer Patients

Colorectal Cancer

Japan
Keio University
Merck Sharp & Dohme LLC; Ohara Pharmaceutical Co., Ltd.

Recruiting

Imatinib Mesylate in Combination With Pembrolizumab in Patients With Melanoma

Melanoma

Japan
Genmab
BioNTech SE

Active, not recruiting

GEN1046 Safety and PK in Subjects With Advanced Solid Malignancies

Solid Tumor

Japan
Eli Lilly and Company

Completed

A Study of Irinotecan, Levofolinate, and 5-Fluorouracil (FOLFIRI) Plus Ramucirumab (IMC-1121B)

Colorectal Carcinoma

Japan
Ludwig Institute for Cancer Research
Mie University

Completed

Safety and Immunogenicity of CHP-HER2 and CHP-NY-ESO-1 Protein With OK-432 in Antigen-Expressing Cancers

Stomach Cancer | Breast Cancer | Esophageal Cancer | Ovarian Cancer | Lung Cancer

Japan
Translational Research Center for Medical Innovation...
Okayama University; Japanese Gynecologic Oncology Group (JGOG)

Recruiting

Prospective Cohort Study of Germline Variant Carriers With BRCA1 or BRCA2

Fallopian Tube Carcinoma | Peritoneal Carcinoma | Ovarian Carcinoma | BRCA1 and/or BRCA2 Variant Carriers

Japan
Nagoya University
Japan Agency for Medical Research and Development

Recruiting

Investigator-initiated Clinical Trial of MIKE-1 (MIKE-1)

Pancreatic Cancer

Japan
City of Hope Medical Center

Recruiting

Early Detection of Advanced Adenomas and Colorectal Cancer (AACRC)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Disorders | Colorectal Adenocarcinoma | Colorectal Cancer Stage II | Colorectal Cancer Stage III | Colorectal Cancer Stage IV | Colorectal Polyp | Colorectal Neoplasms Malignant | Colorectal Adenomatous Polyp | Colorectal Cancer Stage I | Colorectal Adenoma... and other conditions

United States, Italy, China, Spain, Japan
Japan Study Group of Prostate Cancer

Enrolling by invitation

Asia Study Group of Prostate Cancer (A-CaP Study)

Prostate Cancer

Japan
Eisai Co., Ltd.

Completed

A Study on Safety and Efficacy in Patients With Soft Tissue Sarcomas (HAL03T)

Sarcoma, Soft Tissue

Japan
Telix International Pty Ltd

Completed

Evaluation of Safety, Biodistibution and Sensitivity/Specificity of PET/CT Imaging With 89Zr-TLX250 in Subjects With RCC (ZIRDAC-JP)

Carcinoma, Renal Cell | Clear Cell Renal Cell Carcinoma

Japan
Bristol-Myers Squibb

Completed

Japanese Study of Ipilimumab Administered in Combination With Paclitaxel/Carboplatin in Patients With Nonsmall-cell Lung Cancer

Non-Small Cell Lung Cancer

Japan
Taiho Pharmaceutical Co., Ltd.
Daiichi Sankyo Co., Ltd.

Completed

Phase II/III Trial of CPT-11/5-FU/l-LV Versus CPT-11/TS-1 as Second Line Chemotherapy of Unresectable Colorectal Cancer

Colorectal Cancer

Japan
Tokyo University
Human Genome Center, Institute of Medical Science, University of Tokyo

Terminated

Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Colorectal Cancer

Colorectal Cancer | Rectal Cancer | Colon Cancer

Japan
Bristol-Myers Squibb

Recruiting

A Study of Yervoy and Opdivo Combination Therapy in Participants With Unresectable Advanced/Recurrent Malignant Pleural Mesothelioma (MPM)

Mesothelioma, Malignant

Japan
Boston Scientific Corporation

Active, not recruiting

Intra-operative Pancreatoscopy in Patients With IPMN

Intraductal Papillary Mucinous Neoplasm

United States, Netherlands, China, India, Japan, Sweden
AstraZeneca

Active, not recruiting

An Open-Label Phase 1 Study of Ceralasertib in Japanese Patients With Advanced Solid Malignancies

Advanced Solid Malignancies

Japan
Pfizer

Completed

Study Of AG-013736 (Axitinib) In Patients With Advanced Solid Tumors

Carcinoma

Japan
Tadashi Watabe

Recruiting

Evaluation Using FAPI-PET Targeting Cancer-associated Fibroblasts

Neoplasms

Japan
Bayer

Completed

Japanese BAY86-9766 Monotherapy Phase I Study

Neoplasms

Japan
Cancer Intelligence Care Systems, Inc.
Stella Pharma Corporation

Completed

Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma

Angiosarcoma | Malignant Melanoma

Japan
Tokyo University
Human Genome Center, Institute of Medical Science, University of Tokyo

Unknown

Human Leukocyte Antigen-A*2402-Restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreas Neoplasms

Japan
Bristol-Myers Squibb
Ono Pharmaceutical Co. Ltd

Completed

Yervoy® Postmarketing Surveillance for Patients in Japan With Unresectable, Malignant Melanoma

Melanoma

Japan
Komagome Hospital

Unknown

Bone Marrow-derived Cells' Contribution to Tumor Formation and Inflammation

Gastrointestinal Neoplasms

Japan
Astellas Pharma Global Development, Inc.

Active, not recruiting

A Study to Assess the Efficacy and Safety of IMAB362 in Combination With Nab-Paclitaxel and Gemcitabine (Nab-P + GEM) as First Line Treatment in Subjects With Claudin 18.2 (CLDN18.2) Positive, Metastatic Pancreatic Adenocarcinoma

Pancreatic Cancer | Metastatic Pancreatic Adenocarcinoma | Metastatic Pancreatic Cancer

United States, Korea, Republic of, Japan, China, France, Turkey, Italy, Australia, Brazil, Ireland, Mexico, Spain, Taiwan
Kyoto University

Completed

Low-dose Peg-interferon Plus Ribavirin (IFN/RBV) for Prevention of Hepatocellular Carcinoma (HCC) Recurrence in Patients Who Had Surgery to Remove Primary HCC

Hepatitis C, Chronic

Japan
Japan Clinical Cancer Research Organization
Taiho Pharmaceutical Co., Ltd.

Unknown

Preoperative S-1/OHP With Radiation Therapy for Low-lying Rectal Carcinoma in Neo-adjuvant Setting

Rectal Carcinoma

Japan
Bristol-Myers Squibb
Ono Pharma USA Inc

Completed

A Study of Effectiveness and Safety of the First-Line Nivolumab Plus Ipilimumab With or Without Chemotherapy for Advanced/Recurrent Non-Small Cell Lung Cancer in Japan (LIGHT-NING)

Non-Small Cell Lung Cancer

Japan
Institut de Recherches Internationales Servier
ADIR, a Servier Group company

Completed

Phase II of BAX2398/5-FU/Calcium Levofolinate in Pancreatic Cancer

Metastatic Pancreatic Cancer

Japan
Pfizer

Completed

Study of CP-751,871 in Combination With Carboplatin and Paclitaxel in Advanced Lung Cancer

Carcinoma, Non-Small-Cell Lung

Japan
AstraZeneca

Completed

Real-World Treatment Patterns and Patient Reported Outcome in COPD (REMIND) (REMIND)

COPD

Japan
Eli Lilly and Company

Completed

A Study of LY2584702 in Solid Tumors

Cancer

Japan
Tokyo University
Human Genome Center, Institute of Medical Science, University of Tokyo

Terminated

Histocompatibility Leukocyte Antigen (HLA)-A*0201 Restricted Peptide Vaccine Therapy in Patients With Colorectal Cancer

Colorectal Cancer | Rectal Cancer | Colon Cancer

Japan
Tokyo University
Human Genome Center, Institute of Medical Science, University of Tokyo

Terminated

Human Leukocyte Antigen-A*02:01-restricted Tumor Vessel Specific Peptide Vaccination for Advanced Pancreatic Cancer

Pancreatic Cancer | Pancreas Neoplasms

Japan
Keio University

Terminated

Safety and Efficacy Study of Salvage Chemotherapy (R-ESHAP) to Treat Relapsed and Refractory Aggressive Non-Hodgkin's Lymphoma

Lymphoma, Non-Hodgkin

Japan
Puma Biotechnology, Inc.

Completed

Study Evaluating Safety And Tolerability, Solid Tumor

Advanced Malignant Solid Tumors

Japan
Puma Biotechnology, Inc.

Completed

Study Evaluating Neratinib In Combination With Vinorelbine In Subjects With Advanced Or Metastatic Solid Tumors

Advanced Malignant Solid Tumors

Japan
Astellas Pharma Inc

Completed

A Study of IMAB362 in Japanese Subjects With Locally Advanced or Metastatic Gastric or Gastro-esophageal Junction (GEJ) Adenocarcinoma

Gastric Cancer | Gastro-esophageal Junction (GEJ) Cancer

Japan
Wakayama Medical University
Osaka University; Kyoto Prefectural University of Medicine; Nara Medical University and other collaborators

Completed

Trial Assessing Roux-en-Y Anastomosis of the Pancreatic Stump to Prevent Pancreatic Fistula Following Distal Pancreatectomy

Pancreatic Cancer | Chronic Pancreatitis | Pancreatic Cystic Lesions | Pancreatic Neuroendocrine Tumors | Pancreatic Pseudocysts

Japan
Tokyo University
Human Genome Center, Institute of Medical Science, University of Tokyo

Terminated

Histocompatibility Leukocyte Antigen (HLA)-A*2402 Restricted Peptide Vaccine Therapy in Patients With Breast Cancer

Breast Cancer

Japan

Clinical Trials on Metastatic Neoplasm in Japan

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