Clinical Trials on Metastatic Solid Tissue Tumors in Spain

Total 1060 results

Immunocore Ltd

Recruiting

IMC-F106C Regimen Versus Nivolumab Regimens in Previously Untreated Advanced Melanoma (PRISM-MEL-301) (PRISM-MEL-301)

Advanced Melanoma

Spain, United States, Australia, Austria, Poland, France, Germany, Italy, Switzerland
Amgen

Terminated

Study of AMG 199 in Subjects With MUC17-Positive Solid Tumors Including Gastric, Gastroesophageal Junction, Colorectal, and Pancreatic Cancers

MUC17-positive Solid Tumors

United States, Korea, Republic of, Taiwan, Spain, Austria, France, Japan, Germany, Netherlands
GlaxoSmithKline

Terminated

Dose Escalation and Dose Expansion Study of GSK525762 in Combination With Androgen Deprivation Therapy in Participants With Castrate-resistant Prostate Cancer

Solid Tumours

United States, Spain, Australia, United Kingdom
AbbVie

Completed

ABBV-085, an Antibody Drug Conjugate, in Subjects With Advanced Solid Tumors

Advanced Solid Tumors | Squamous Cell Carcinoma of the Head and Neck | Undifferentiated Pleomorphic Sarcoma | Carcinoma of the Breast

United States, France, Spain
AstraZeneca
Daiichi Sankyo Co., Ltd.

Recruiting

A Phase 2 Study of T-DXd in Patients With Selected HER2 Expressing Tumors (DPT02)

Part 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer | Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal Cancer

Canada, Korea, Republic of, Taiwan, United States, Italy, United Kingdom, Thailand, Russian Federation, India, Belgium, Australia, Poland, Spain, Japan, Brazil, Czechia, Netherlands
Spanish Breast Cancer Research Group
Novartis

Completed

Pamidronate Administration in Breast Cancer Patients With Bone Metastases

Breast Cancer | Neoplasm Metastasis

Spain
Pfizer

Active, not recruiting

Continued Access Study for Participants Deriving Benefit in Pfizer-Sponsored Avelumab Parent Studies That Are Closing

Ovarian Cancer | NSCLC | Solid Tumors | Urothelial Cancer | Advanced Malignancies

Hungary, Spain, United States, Canada, Taiwan, Japan, Serbia, Italy, New Zealand, Australia, Mexico, Russian Federation, United Kingdom, France, Korea, Republic of, Belgium, Poland, Denmark, Israel
Juan M Garcia-Gomez
Hospital Universitario 12 de Octubre; Hospital Clínico Universitario de Valencia

Recruiting

BIOhabitats: Biological Validation of Vascular Habitats Within Astrocytoma Grade 4 at Molecular, Cellular, and Histopathological Levels (BIOhabitats)

Glioblastoma | Glioblastoma Multiforme | High Grade Glioma | Astrocytoma, Grade IV | Glioblastoma, IDH-mutant | Glioblastoma, IDH-wildtype | Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype | Glioblastoma IDH (Isocitrate Dehydrogenase) Mutant

Spain
Hoffmann-La Roche

Completed

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Melanoma (Morpheus-Melanoma)

Melanoma

United States, Italy, Australia, France, Spain, Netherlands
Hospital San Carlos, Madrid

Completed

"Oncologic Results and Risk Factors for Recurrence in Patients With Locally Advanced Rectal Cancer and Pathologic Complete Response After Neoadjuvant Treatment. Results From an Observational Retrospective Multicenter Long-term Follow-up Study".

Rectal Cancer Stage II | Rectal Cancer Stage III | Rectal Cancer, Adenocarcinoma | Distant Metastasis | Local Recurrence of Malignant Tumor of Rectum

Spain
Incyte Corporation

Completed

Arginase Inhibitor INCB001158 as a Single Agent and in Combination With Immune Checkpoint Therapy in Patients With Advanced/Metastatic Solid Tumors

Head and Neck Cancer | Gastric Cancer | Lung Cancer | Metastatic Cancer | Mesothelioma | Bladder Cancer | Solid Tumors | Renal Cell Carcinoma (RCC) | Colorectal Cancer (CRC) | UC (Urothelial Cancer)

Italy, Spain, United States, Netherlands
Grupo Espanol de Investigacion en Sarcomas

Recruiting

Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK ((SELNET))

Gastrointestinal Stromal Tumors | Soft-tissue Sarcoma | Bone Sarcoma

France, Spain, Argentina, Costa Rica, Brazil, Italy, Mexico, Peru
Sierra Oncology LLC - a GSK company

Completed

A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects

Advanced Solid Tumors

Spain, United Kingdom
Incyte Corporation

Completed

A Study of INCMGA00012 in Participants With Selected Solid Tumors (POD1UM-203)

Metastatic Melanoma | Unresectable Melanoma | Metastatic Urothelial Cancer | Metastatic Non-small Cell Lung Cancer | Locally Advanced Renal Cell Carcinoma | Locally Advanced Urothelial Cancer | Metastatic Clear-Cell Renal Cell Carcinoma

France, Spain, United States, Italy, Austria, Romania, Poland, Hungary
Polyphor Ltd.

Completed

Dose Escalation of POL6326 in Combination With Eribulin in Patients With Metastatic Breast Cancer

Metastatic Breast Cancer

Spain, United States
Janssen Research & Development, LLC

Active, not recruiting

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Neoplasms | Myelodysplastic Syndromes | Non-Hodgkin Lymphoma | Solid Tumor, Adult

United States, Spain, Israel, Germany, Canada
Grupo Espanol de Investigacion en Sarcomas
Bayer

Completed

Single Agent Regorafenib in First-line for Metastatic/Unresectable KIT/PDGFR Wild Type GIST (REGISTRI)

Gastrointestinal Stromal Tumors

Spain, France, Italy
AstraZeneca

Completed

Investigating Safety, Tolerability and Efficacy of AZD5363 When Combined With Paclitaxel in Breast Cancer Patients (BEECH)

Advanced or Metastatic Breast Cancer | ER+ve Advanced or Metastatic Breast Cancer

Canada, France, Korea, Republic of, Czechia, Peru, United Kingdom, Spain, Japan, Mexico, Singapore, Bulgaria
Fundació Sant Joan de Déu

Active, not recruiting

Evaluate Safety and the Oncolitic Adenovirus VCN-01 Activity in Patients With Refractory Retinoblastoma (RTB)

Retinoblastoma, Recurrent

Spain
Grupo Espanol de Tumores Neuroendocrinos
Novartis Pharmaceuticals; European Neuroendocrine Tumor Society; Kantar Health

Completed

Efficacy and Safety of Everolimus and (STZ-5FU) Given One Upfront the Other Upon Progression in Advanced Pancreatic Neuroendocrine Tumor (pNET) (SEQTOR)

Neuroendocrine Tumors

Spain, United Kingdom, Denmark, France, Netherlands, Germany, Italy, Sweden
SOLTI Breast Cancer Research Group

Completed

Study of Palbociclib and Trastuzumab With Endocrine Therapy in HER2-positive Metastatic Breast Cancer (PATRICIA II)

Metastatic Breast Cancer

Spain
Pfizer

Completed

LGX818 and MEK162 in Combination With a Third Agent (BKM120, LEE011, BGJ398 or INC280) in Advanced BRAF Melanoma (LOGIC-2)

Melanoma

United States, Australia, Canada, Germany, Italy, Netherlands, Spain, Switzerland, United Kingdom
Celgene

Completed

CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma

Glioblastoma | Astrocytoma

United States, Spain
EMD Serono Research & Development Institute, Inc.

Completed

Avelumab in Participants With Merkel Cell Carcinoma (JAVELIN Merkel 200)

Carcinoma, Merkel Cell

United States, Spain, Australia, Italy, Germany, France, Japan
Hospital Universitario Reina Sofia de Cordoba

Completed

New Therapeutic Approach in Upper Limb Lymphedema Secondary to Breast Cancer: Activity-oriented Proprioceptive Antiedema Therapy (TAPA)

Breast Cancer Lymphedema | Post-Mastectomy Secondary Lymphedema

Spain
ITM Solucin GmbH
ABX CRO; PSI CRO

Active, not recruiting

Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients (COMPETE)

Neuroendocrine Tumors

Germany, France, United States, United Kingdom, Australia, Italy, Belgium, Switzerland, Czechia, Spain, Austria, Netherlands, Poland, South Africa
Spanish Breast Cancer Research Group
AstraZeneca

Recruiting

Trastuzumab Deruxtecan in First-line HER2-positive Locally Advanced/MBC Patients Resistant to Trastuzumab+Pertuzumab (TRANSCENDER)

Metastatic Breast Cancer | Locally Advanced Breast Cancer

Spain
Spanish Breast Cancer Research Group
Eli Lilly and Company

Completed

Vinorelbine Versus Gemcitabine Plus Vinorelbine in Metastatic Breast Cancer Patients

Breast Cancer | Neoplasm Metastasis

Spain, Venezuela
AbbVie

Completed

A Study to Evaluate the Effects of Veliparib on Heart Rhythms in Patients With Solid Tumors

Breast Cancer | Gastric Cancer | Ovarian Cancer | Lung Cancer | Colon Cancer | Solid Tumors

United States, Netherlands, Spain
Bristol-Myers Squibb

Completed

A Study to Assess Safety of Relatlimab With Ipilimumab in Participants With Advanced Melanoma Who Progressed on Anti-Programmed Cell Death Protein 1 (Anti-PD-1) Treatment

Melanoma

United States, Belgium, Canada, Germany, Spain
Institut d'Investigació Biomèdica de Bellvitge

Recruiting

Effect of Loratadine in Lymphangioleiomyomatosis (LORALAM)

Lymphangioleiomyomatosis

Spain
Ipsen

Terminated

Study to Assess the Efficacy and Safety of Different Doses of BIM 23A760 in Patients With Carcinoid Syndrome (CAMPANULA)

Carcinoid Syndrome

Spain, Belgium, Ireland, Czechia, Israel, France, United Kingdom, Latvia, Germany, Russian Federation, Slovakia, Italy, Netherlands, Finland, Austria, Poland, Sweden, Ukraine
Grupo Español de Investigación en Neurooncología
Tilray; Medical Cannabis Bike Tour; Voices Against Brain Cancer

Recruiting

TN-TC11G (THC+CBD) Combination With Temozolomide and Radiotherapy in Patients With Newly-diagnosed Glioblastoma (GEINOCANN)

Glioblastoma

Spain
Genta Incorporated

Completed

Trial of Dacarbazine With or Without Genasense in Advanced Melanoma (AGENDA)

Melanoma

United States, France, United Kingdom, Spain, Switzerland, Australia, Canada, Germany, Poland, Italy, Austria, Czech Republic
Merck Sharp & Dohme LLC

Recruiting

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

Von Hippel-Lindau Disease | Pancreatic Neuroendocrine Tumor | Pheochromocytoma/Paraganglioma | Advanced Gastrointestinal Stromal Tumor | HIF-2α Mutated Cancers

Canada, United States, Denmark, France, Germany, Hungary, Italy, Russian Federation, Spain, Sweden, Turkey, Israel, United Kingdom, Netherlands, Australia, China, Singapore, Japan
Hoffmann-La Roche

Recruiting

A Study of Multiple Doses of RO7247669 in Participants With Previously Untreated Unresectable or Metastatic Melanoma

Melanoma

Brazil, Czechia, Spain, Turkey, New Zealand, Canada, Australia, Poland, Slovakia, Greece
Grupo Español de Investigación en Neurooncología
Pfizer

Completed

Safety and Efficacy of PF-299804 (Dacomitinib), a Pan-HER Irreversible Inhibitor, in Patients With Recurrent Glioblastoma With EGFR Amplification or Presence of EGFRvIII Mutation. A Phase II CT.

Glioblastoma | Brain Tumor, Recurrent

Spain
Genmab
AbbVie

Terminated

A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors

Esophageal Cancer | Prostate Cancer | Bladder Cancer | Non-small Cell Lung Cancer (NSCLC) | Uterine Cancer | Triple Negative Breast Cancer (TNBC) | Squamous Cell Carcinoma of Head and Neck (SCCHN) | Locally Advanced or Metastatic Solid Tumor(s)

Spain, Israel, United States, Denmark
PharmaMar

Completed

Study Escalating Doses of PM01183 in Combination With Fixed Doxorubicin in Patients With Specific Advanced Unresectable Solid Tumors

Neuroendocrine Tumors | Endometrial Adenocarcinomas | Small-cell Lung Cancer With Less Than 2 Prior Cytotoxic-containing Lines of Therapy

Spain, United Kingdom
Janssen Research & Development, LLC

Completed

A Study That Provides Long-term Safety Follow-up and Examines Long-term Exposure to Abiraterone Acetate

Metastatic Breast Cancer | Metastatic Castration-resistant Prostate Cancer

United States, Belgium, Spain, Germany, Sweden, Australia, United Kingdom
ETOP IBCSG Partners Foundation
Breast International Group

Completed

Schedules of Nab-Paclitaxel in Metastatic Breast Cancer (SNAP)

Metastatic Breastcancer

Spain, Ireland, Italy, Switzerland, Slovenia, Belgium
Fundación de Investigación Biomédica - Hospital...

Completed

Circulating Tumor Cells in High-Risk Prostate Cancer Treated With High-dose Radiotherapy and Hormone Therapy

Patients With High-risk Prostate Cancer

Spain
AstraZeneca

Active, not recruiting

Safety, Tolerability & Potential Anti-cancer Activity of Increasing Doses of AZD5363 in Different Treatment Schedules

Cervical Cancer | Ovarian Cancer | Pharmacokinetics | Endometrial Cancer | Pharmacodynamics | Safety and Tolerability | Advanced Solid Malignancy | Tumour Response | Advanced or Metastatic Breast Cancer | PIK3CA | AKT1 | PTEN | ER Positive | HER2 Positive

United States, Italy, Canada, France, Japan, United Kingdom, Spain, Netherlands, Denmark, Singapore
AbbVie

Completed

A Study Evaluating Veliparib as a Single Agent or in Combination With Chemotherapy in Subjects With Solid Tumors

Breast Cancer | Gastric Cancer | Ovarian Cancer | Lung Cancer | Colon Cancer | Solid Tumors

United States, Netherlands, Spain
Santiago R. Leal-Noval
Instituto de Salud Carlos III

Unknown

Hemostasis Alterations in Neurosurgical Patients (ABCD)

Glioma | Surgery | Coagulopathy | Acquired Platelet Function Disorder | Thromboelastometry

Spain
MedSIR

Completed

Molecular Mechanisms of Resistance and Sensitivity to Palbociclib Re-challenge in ER+ mBC (BioPER)

Metastatic Breast Cancer

Spain, Italy
Genentech, Inc.

Completed

A Study of GDC-0084 in Patients With Progressive or Recurrent High-Grade Glioma

Glioblastoma, Glioma

United States, Spain
Hospital Sant Joan de Deu
Fundació Sant Joan de Déu; Ministry of Health, Spain; Hospital Universitari General...

Terminated

Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular Stage

Retinoblastoma

Spain
AstraZeneca

Completed

Comparison of AZD6244 in Combination With Dacarbazine Versus (vs) Dacarbazine Alone in BRAF Mutation Positive Melanoma Patients

Melanoma

Sweden, United States, Brazil, Czech Republic, France, Spain, United Kingdom, Germany, Norway, Hungary, Netherlands, Switzerland
Lexicon Pharmaceuticals

Completed

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms (TELEPATH)

Carcinoid Syndrome

United States, Australia, Belgium, Canada, France, Germany, Israel, Italy, Netherlands, Spain, Sweden, United Kingdom

Clinical Trials on Metastatic Solid Tissue Tumors in Spain

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