Clinical Trials on Metastatic Solid Tumors Characterized by HER2/Neu Expression in United States
Total 325 results
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingAdvanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Metastatic Skin Squamous Cell Carcinoma | Unresectable Solid Neoplasm | Metastatic Kidney Medullary Carcinoma | Metastatic Penile Carcinoma | Small Cell Carcinoma | Metastatic Adrenal Gland Pheochromocytoma | Stage IV Penile Cancer... and other conditionsUnited States
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OncoResponse, Inc.RecruitingMelanoma | Cancer | Non Small Cell Lung Cancer | Metastatic Cancer | Advanced Solid Tumor | Leiomyosarcoma | Head and Neck Squamous Cell Carcinoma | Liposarcoma | Malignant Neoplasm | Tumor, SolidUnited States
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ALX Oncology Inc.Active, not recruitingSolid Tumor | Metastatic Cancer | Advanced Cancer | NonHodgkin LymphomaKorea, Republic of, United States
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Virginia Commonwealth UniversityNational Cancer Institute (NCI)TerminatedUnspecified Adult Solid Tumor, Protocol Specific | Bone MetastasesUnited States
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New Approaches to Brain Tumor Therapy ConsortiumNational Cancer Institute (NCI)CompletedUnspecified Adult Solid Tumor, Protocol Specific | Metastatic CancerUnited States
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Menarini GroupTerminatedMetastatic Solid Tumors | Relapsed/Refractory Non-Hodgkin LymphomaItaly, Spain, Belgium, United Kingdom
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Minneamrita Therapeutics LLCTranslational Drug DevelopmentRecruitingBreast Cancer | Gastric Cancer | Pancreatic Cancer | Solid Tumor | Advanced Cancer | Colo-rectal Cancer | Prostate Cancer Metastatic | Solid Carcinoma | Solid Carcinoma of Stomach | Cancer of StomachUnited States
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Novartis PharmaceuticalsCompletedMetastatic Renal Cell Carcinoma | Advanced Solid Tumors | Metastatic Breast CancerSpain, Belgium, Italy, France, United States, New Zealand, United Kingdom
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MacroGenicsActive, not recruitingColorectal Cancer | Advanced Cancer | Prostate Cancer Metastatic | Cutaneous Melanoma | Solid Tumor, Adult | Squamous Cell Non Small Cell Lung CancerUnited States, Spain, Bulgaria, Poland, Ukraine
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National Cancer Institute (NCI)CompletedUnspecified Adult Solid Tumor, Protocol Specific | HER2-positive Breast Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IIIB Breast Cancer | Stage IIIC Breast Cancer | Recurrent Breast CancerUnited States
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Taiho Oncology, Inc.TerminatedNon-Small Cell Lung Cancer | KRAS Gene Mutation | Advanced or Metastatic Solid Tumors Irrespective of Gene AlterationsUnited States
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Northwestern UniversityNational Cancer Institute (NCI)CompletedLymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous Condition | Lymphoproliferative Disorder | Secondary...United States
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City of Hope Medical CenterActive, not recruitingUnspecified Childhood Solid Tumor, Protocol Specific | Solid Tumor | Ewing Sarcoma | Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Neuroblastoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Adult Brain Tumor | Recurrent... and other conditionsUnited States
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Genentech, Inc.Chugai Pharmaceutical Co.RecruitingGastric Cancer | Metastatic Solid Tumor | Non-small Cell Lung Cancer | Pancreatic Ductal AdenocarcinomaKorea, Republic of, Spain, Japan, New Zealand, Australia, United States, Italy, Brazil
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Dana-Farber Cancer InstituteNational Cancer Institute (NCI)CompletedSarcoma | Kidney Cancer | Testicular Germ Cell Tumor | Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Bladder Cancer | Extragonadal Germ Cell Tumor | Carcinoma of Unknown PrimaryUnited States
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Tempus AIGlaxoSmithKlineActive, not recruitingMelanoma | Head and Neck Cancer | Pancreatic Cancer | Esophageal Cancer | Solid Tumor | Metastatic Cancer | Endometrial Cancer | Urologic Cancer | Breast Tumor | Locally Advanced Solid Tumor | Lung Tumor | Colon Tumor, MalignantUnited States
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MacroGenicsCompletedCervical Cancer | Hematologic Neoplasms | Ovarian Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | Squamous Cell Carcinoma of Head and Neck | Cholangiocarcinoma | Small-cell Lung Cancer | TNBC - Triple-Negative Breast Cancer | HER2-positive Advanced Solid TumorsHong Kong, United States, Thailand, Australia, Spain, Bulgaria, Poland, Ukraine
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Hummingbird BioscienceMerck Sharp & Dohme LLCRecruitingCancer | Metastatic Cancer | Triple Negative Breast Cancer | Advanced Solid Tumor | Nonsmall Cell Lung Cancer | Malignant Neoplasm | Tumor, SolidUnited States
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Monte Rosa Therapeutics, IncRecruitingNSCLC | Prostate Cancer | SCLC | DLBCL | High Grade Neuroendocrine Cancer | L-MYC and N-MYC Amplified Solid Tumors | NSCLC With High or Low L-MYC or N-MYC Expression | HR-positive, HER2-negative Breast CancerUnited States, Canada
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SWOG Cancer Research NetworkNational Cancer Institute (NCI)RecruitingCardiotoxicity | Recurrent Breast Carcinoma | HER2/Neu Positive | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7United States, Korea, Republic of, Puerto Rico, Saudi Arabia
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Gradalis, Inc.Temporarily not availableCervical Cancer | Ovarian Cancer | Solid Tumor | Ewing Sarcoma | Uterine Cancer | Ewing's Tumor Metastatic | Ewing's Sarcoma Metastatic | Advanced Gynecological CancersUnited States
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National Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Malignant Solid Neoplasm | Locally Advanced Malignant Solid Neoplasm | Unresectable Malignant Solid... and other conditionsUnited States, Puerto Rico
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Fate TherapeuticsCompletedMelanoma | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | HER2-positive Breast Cancer | Head and Neck Squamous Cell Carcinoma | HER2 Positive Gastric Cancer | EGFR Positive Solid TumorUnited States
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National Cancer Institute (NCI)Active, not recruitingMalignant Solid Neoplasm | Metastatic Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Clinical Stage IV Cutaneous Melanoma AJCC v8United States
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Rahul AggarwalNational Cancer Institute (NCI); U.S. Army Medical Research Acquisition ActivityRecruitingProstate Cancer | Advanced Solid Tumor | Renal Cancer | Urethral Cancer | Solid Tumor, Adult | Metastatic Castration-resistant Prostate CancerUnited States
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Case Comprehensive Cancer CenterNational Cancer Institute (NCI)TerminatedOvarian Cancer | Lung Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Metastatic CancerUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditionsUnited States
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Tyra Biosciences, IncRecruitingSolid Tumor | Bladder Cancer | Advanced Solid Tumor | Urothelial Carcinoma | Metastatic Urothelial Carcinoma | Solid Tumor, Adult | FGFR3 Gene Mutation | Urinary Tract Cancer | Locally Advanced Urothelial Carcinoma | Advanced Urothelial Carcinoma | Non-muscle-invasive Bladder Cancer | FGFR3 Gene Alteration | Urinary... and other conditionsAustralia, United States, France, Spain
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Anatomic Stage IIIB Breast Cancer AJCC v8 | Anatomic Stage IIIC Breast Cancer AJCC v8 | Prognostic Stage III Breast Cancer AJCC v8 | Prognostic Stage IIIA Breast Cancer AJCC v8 | Prognostic Stage IIIB Breast... and other conditionsUnited States
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HutchmedBeiGeneActive, not recruitingSoft Tissue Sarcoma | Small Cell Lung Cancer | Gastric Cancer | Colorectal Cancer | Neuroendocrine Tumors | Metastatic Solid Tumor | Anaplastic Thyroid CancerUnited States
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AbbVieActive, not recruitingCancer | Advanced Solid Tumors | Metastatic Solid Tumors | Triple-Negative Breast Cancer (TNBC) | Non-small-cell-lung-cancer (NSCLC)United States, Australia, France, Israel, Spain, Taiwan
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Merus N.V.Chiltern International Inc.; Q2 Solutions; Oncology Therapeutic Development (OTD) and other collaboratorsRecruitingGastric Cancer | Colorectal Cancer | NSCLC | Head and Neck Squamous Cell Carcinoma | HNSCC | Advanced/Metastatic Solid Tumors | Gastroesophageal-junction CancerUnited States, Spain, Belgium, France, Netherlands, United Kingdom
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H. Lee Moffitt Cancer Center and Research InstituteReliable Cancer TherapiesTerminatedPain | Lymphoma | Cancer | Neoplasm Metastasis | Multiple Myeloma | Hematologic Malignancy | Tumor | Unresectable Malignant Neoplasm | Malignant Solid TumorUnited States
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M.D. Anderson Cancer CenterCompletedHematopoietic and Lymphoid Cell Neoplasm | Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Metastatic... and other conditionsUnited States
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Radiation Therapy Oncology GroupNational Cancer Institute (NCI); NRG OncologyCompletedUnspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Cognitive/Functional EffectsUnited States, Canada
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AstraZenecaActive, not recruitingCervical Cancer | Ovarian Cancer | Pharmacokinetics | Endometrial Cancer | Pharmacodynamics | Safety and Tolerability | Advanced Solid Malignancy | Tumour Response | Advanced or Metastatic Breast Cancer | PIK3CA | AKT1 | PTEN | ER Positive | HER2 PositiveUnited States, Italy, Canada, France, Japan, United Kingdom, Spain, Netherlands, Denmark, Singapore
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Abramson Cancer Center of the University of PennsylvaniaCompletedAdult Solid Tumor | HER2-positive Breast Cancer | Recurrent Melanoma | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Stage IV Ovarian Germ Cell Tumor | Recurrent Breast Cancer | Estrogen Receptor-negative Breast Cancer | Estrogen Receptor-positive Breast Cancer | Progesterone Receptor-negative... and other conditionsUnited States
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EMD Serono Research & Development Institute, Inc.Merck KGaA, Darmstadt, GermanyCompletedEsophageal Cancer | Non-Small Cell Lung Cancer | Metastatic Solid TumorsUnited States, Canada
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Dracen Pharmaceuticals, Inc.TerminatedAdvanced Solid Tumor | Non Small Cell Lung Cancer MetastaticUnited States, Taiwan, Germany, Singapore, Spain
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Radiation Therapy Oncology GroupNational Cancer Institute (NCI)CompletedUnspecified Adult Solid Tumor, Protocol Specific | Metastatic Cancer | Radiation ToxicityUnited States, Canada
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Dana-Farber Cancer InstituteNH TherAguix SASRecruitingMelanoma | Breast Cancer | Colorectal Cancer | Lung Cancer | Brain Cancer | Brain Tumor | HER2-positive Breast Cancer | Gastrointestinal Cancer | Brain Metastases | SRS | SRT | Whole Brain Radiation | Stereotactic Radiation | AGuIX | Nanoparticle | CysticUnited States
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CellCentric Ltd.RecruitingAdvanced Solid Tumors | Metastatic Breast Cancer | Non-small Cell Lung Cancer | Metastatic Castration-Resistant Prostate CancerUnited Kingdom, United States, Netherlands, France, Spain, Sweden
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Angiochem IncCompletedAdvanced Solid Tumors With and Without Brain MetastasesUnited States
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Philogen S.p.A.CompletedBrain Metastases From Solid TumorsItaly, United Kingdom
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Processa PharmaceuticalsCompletedSolid Tumor | Metastatic Bladder CancerUnited States
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AstraZenecaMedImmune LLCActive, not recruitingAdvanced Solid Tumors & Metastatic Squamous Cell Carcinoma of the Head and NeckSpain, United States, Belgium, Germany, United Kingdom, Italy
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CelgeneCompletedBreast Cancer | Metastatic Breast Cancer | Stage IV Breast Cancer | Triple-negative Breast Cancer | Recurrent Breast Cancer | Breast Tumor | Cancer of the Breast | Triple-negative Metastatic Breast Cancer | Estrogen Receptor- Negative Breast Cancer | HER2- Negative Breast Cancer | Progesterone Receptor- Negative...United States, United Kingdom, Italy, Germany, Spain, Canada, Portugal, Australia, Austria, Greece, Brazil, France
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IpsenCompletedTriple Negative Breast Cancer | Solid Tumors | ER/PR Positive Breast Cancer | Metastatic Breast Cancer With Active Brain MetastasisUnited States
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Case Comprehensive Cancer CenterNational Cancer Institute (NCI)WithdrawnLymphoma | Unspecified Childhood Solid Tumor, Protocol Specific | Leukemia | Unspecified Adult Solid Tumor, Protocol Specific | Long-term Effects Secondary to Cancer Therapy in Children | Long-term Effects Secondary to Cancer Therapy in Adults | Sexuality and Reproductive Issues | Sexual Dysfunction...United States
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National Cancer Institute (NCI)Active, not recruitingStage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Metastatic Pancreatic Adenocarcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Unresectable Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Unresectable Pancreatic Adenocarcinoma | Metastatic... and other conditionsUnited States