Clinical Trials on Metastatic Thymic Neuroendocrine Neoplasm

Total 12652 results

National Cancer Institute (NCI)

Completed

Multicenter Phase II Study of IMC-A12 in Patients With Thymoma and Thymic Carcinoma Who Have Been Previously Treated With Chemotherapy

Thymic Carcinoma | Thymoma | Thymic Carcinoid | Thymic Neuroendocrine Tumors

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing Cabozantinib in Patients With Advanced Pancreatic Neuroendocrine and Carcinoid Tumors

Carcinoid Tumor | Functioning Pancreatic Neuroendocrine Tumor | Intermediate Grade Lung Neuroendocrine Neoplasm | Locally Advanced Pancreatic Neuroendocrine Tumor | Locally Advanced Unresectable Digestive System Neuroendocrine Neoplasm | Low Grade Lung Neuroendocrine Neoplasm | Metastatic Digestive... and other conditions

United States
SWOG Cancer Research Network
National Cancer Institute (NCI)

Active, not recruiting

Carboplatin and Paclitaxel With or Without Ramucirumab in Treating Patients With Locally Advanced, Recurrent, or Metastatic Thymic Cancer That Cannot Be Removed by Surgery

Unresectable Thymic Carcinoma | Metastatic Thymic Carcinoma | Locally Advanced Thymic Carcinoma | Recurrent Thymic Carcinoma

United States
MedSIR
Merck Sharp & Dohme LLC

Active, not recruiting

Combination of Pembrolizumab and Lenvatinib, in Pre-treated Thymic CArcinoma paTIents (PECATI)

Metastatic Thymic Carcinoma | Thymoma Type B3

Spain, France, Italy
Enzyvant Therapeutics GmBH

Approved for marketing

Expanded Access Protocol Thymus Transplantation

Immunodeficiency | Poor Thymic Function | Athymia | Immunoreconstitution | Thymus Transplantation | Low T Cell Numbers
Shanghai YingLi Pharmaceutical Co. Ltd.

Not yet recruiting

A Phase 2 Clinical Study of YY-20394 in Patients With Relapsed/Refractory Thymic Cancer

Effectiveness，Safety，Thymic Cancer
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

Neoadjuvant Treatment For Locally Advanced Thymic Cancer

Thymic Carcinoma

China
Fudan University

Recruiting

Postoperative Adjuvant Chemotherapy for Thymic Cancer (FUSCC-Thymic 3)

Thymic Carcinoma

China
Shanghai Chest Hospital

Recruiting

Molecular Analysis and Treatment Options of Thymic Malignancies

Thymic Carcinoma | Thymic Epithelial Tumor | Thymic Cancer

China
Samsung Medical Center

Completed

Neoadjuvant Chemotherapy for Locally Advanced Thymic Cancer

Locally Advanced Stage III or IV Thymic Cancer

Korea, Republic of
National Cancer Institute (NCI)

Active, not recruiting

Testing the Combination of XL184 (Cabozantinib), Nivolumab, and Ipilimumab for Poorly Differentiated Neuroendocrine Tumors

Metastatic Neuroendocrine Neoplasm | Metastatic Neuroendocrine Carcinoma | Metastatic Large Cell Neuroendocrine Carcinoma | Metastatic Small Cell Neuroendocrine Carcinoma

United States, Canada
Erasmus Medical Center
Hospices Civils de Lyon; Maastro Clinic, The Netherlands

Recruiting

Artificial Intelligence Prediction Tool in Thymic Epithelial Tumors (INTHYM)

Thymic Carcinoma | Thymoma | Thymic Epithelial Tumor | Thymoma and Thymic Carcinoma

Netherlands
Samsung Medical Center

Completed

A Study of Pembrolizumab for Patients With Thymic Epithelial Tumor

Thymic Epithelial Tumors
Fudan University

Recruiting

Adjuvant Treatment for Incomplete Resection Thymoma or Thymic Carcinoma

Thymoma and Thymic Carcinoma

China
Fudan University

Completed

Chemoradiotherapy for Limited Advanced Unresectable Thymic Epithelial Tumors

Thymoma and Thymic Carcinoma

China
Heather Wakelee
Celgene

Completed

A Phase 2 Study of Amrubicin in Relapsed or Refractory Thymic Malignancies

Thymic Carcinoma | Thymoma | Thymus Cancer

United States
Morten Mau-Soerensen
Hospices Civils de Lyon; Gustave Roussy, Cancer Campus, Grand Paris; Institut... and other collaborators

Unknown

Selinexor in Patients With Advanced Thymoma and Thymic Carcinoma (TET-SEL)

Thymoma | Advanced Thymic Epithelial Tumour

Denmark, France
Sun Yat-sen University

Active, not recruiting

Hypofractionated Chemoradiotherapy and Thymosin α1 in Unresectable or Recurrent Thymic Epithelial Tumor

Thymoma and Thymic Carcinoma

China
Jian Chen

Recruiting

Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial Tumors

Carbon Ion Radiotherapy, Thymoma, Thymic Carcinoma, Radiotherapy, Chemotherapy

China
National Cancer Institute (NCI)

Recruiting

Bintrafusp Alfa (M7824) in Subjects With Thymoma and Thymic Carcinoma

Thymic Epithelial Tumor | Thymic Cancer | Recurrent Thymoma

United States
National Cancer Institute (NCI)

Recruiting

PT-112 in Subjects With Thymoma and Thymic Carcinoma

Thymic Epithelial Tumor | Thymic Cancer | Recurrent Thymoma

United States
Georgetown University
Hackensack Meridian Health; Karyopharm Therapeutics Inc

Terminated

Selinexor in Patients With Advanced Thymic Epithelial Tumor Progressing After Primary Chemotherapy (SELECT)

Thymoma | Advanced Thymic Epithelial Tumor

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors

Metastatic Digestive System Neuroendocrine Neoplasm | Metastatic Neuroendocrine Tumor

United States
Samsung Medical Center

Unknown

A Phase II Study of Palbociclib for Recurrent or Refractory Advanced Thymic Epithelial Tumor

Thymic Cancer

Korea, Republic of
National Cancer Institute (NCI)

Recruiting

Testing Lutetium Lu 177 Dotatate in Patients With Somatostatin Receptor Positive Advanced Bronchial Neuroendocrine Tumors

Locally Advanced Lung Neuroendocrine Neoplasm | Lung Neuroendocrine Neoplasm | Metastatic Lung Neuroendocrine Neoplasm | Recurrent Lung Neuroendocrine Neoplasm | Unresectable Lung Neuroendocrine Neoplasm | Advanced Lung Neuroendocrine Tumor | Functioning Lung Neuroendocrine Tumor | Lung Neuroendocrine... and other conditions

United States
Georgetown University
Merck Sharp & Dohme LLC; Incyte Corporation

Unknown

Pembrolizumab and Epacadostat in Patients With Thymic Carcinoma

Thymic Carcinoma | Thymus Neoplasms | Thymus Cancer

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Intensity-Modulated Pleural Radiation Therapy (IMPRINT) in People With Thymic Cancer That Has Spread to the Lining of the Lungs and Chest

Pleural Metastases | Thymic Malignancies

United States
National Cancer Institute (NCI)

Recruiting

Comparing Retreatment of 177Lu-DOTATATE PRRT Versus Everolimus in Patients With Metastatic Unresectable Midgut Neuroendocrine Tumors, NET RETREAT Trial

Metastatic Midgut Neuroendocrine Tumor | Unresectable Midgut Neuroendocrine Tumor | Metastatic Midgut Neuroendocrine Tumor G1 | Metastatic Midgut Neuroendocrine Tumor G2

United States, Canada
M.D. Anderson Cancer Center
TerSera Therapeutics LLC

Recruiting

Telotristat Ethyl for the Treatment of Carcinoid Heart Disease in Patients With Metastatic Neuroendocrine Tumor

Locally Advanced Neuroendocrine Neoplasm | Metastatic Neuroendocrine Neoplasm

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Novartis

Completed

Ribociclib in Treating Patients With Advanced Neuroendocrine Tumors of Foregut Origin

Intermediate Grade Lung Neuroendocrine Neoplasm | Low Grade Lung Neuroendocrine Neoplasm | Functional Pancreatic Neuroendocrine Tumor | Advanced Digestive System Neuroendocrine Neoplasm | Duodenal Neuroendocrine Tumor G1 | Gastric Neuroendocrine Tumor | Nonfunctional Pancreatic Neuroendocrine... and other conditions

United States
Shanghai Cancer Hospital, China

Not yet recruiting

Abscopal Effect of SBRT in Combination With rhGM-CSF and INF-α 2b for Metastatic Thymic Epithelial Tumors

Thymic Epithelial Tumor

China
Intergroupe Francophone de Cancerologie Thoracique

Recruiting

French National Observatory of Patients With Thymic Epithelial Tumor (RYTHMIC)

Thymic Epithelial Tumor

France
National Cancer Center, Japan
Merck Sharp & Dohme LLC

Recruiting

First-line CBDCA/PTX/LEN/Pembrolizumab Combination for Previously Untreated Advanced or Recurrent Thymic Carcinomas (Artemis) (Artemis)

Untreated Advanced or Recurrent Thymic Carcinomas

Japan
Third Military Medical University

Completed

Prospective Study of Stereotactic Body Radiation Therapy for Thymoma Inoma: Therapeutic Effect and Toxicity Assessment

Thymoma | Thymic Tumor

China
Indiana University School of Medicine
Genentech, Inc.

Completed

A Study to Test the Safety and Efficacy of Erlotinib Plus Bevacizumab to Treat Advanced Thymoma and Thymic Cancer

Thymoma | Thymic Cancer

United States
Excel Diagnostics and Nuclear Oncology Center

Withdrawn

Phase-II Study of Lu177DOTATOC in Adults With STTR(+)Pulmonary, Pheochromocytoma, Paraganglioma, Unknown Primary, Thymus NETs (PUTNET), or Any Other Non-.GEP-NET. (PUTNET)

Neuroendocrine Tumors | Pheochromocytoma | Paraganglioma | Unknown Primary Tumors | Pulmonary Neuroendocrine Neoplasm | Thymus Carcinoid | Neuroendocrine Skin Carcinoma | Neuroendocrine Breast Tumor | Neuroendocrine Carcinoma Metastatic | Neuroendocrine Neoplasm of Ovary

United States
Cancer Institute and Hospital, Chinese Academy...

Recruiting

Adjuvant Hypofractionation Radiotherapy for Thymic Epithelial Tumours After Complete Resection

Thymus Neoplasms

China
National Cancer Institute (NCI)
National Institutes of Health Clinical Center (CC)

Terminated

T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Melanoma

Metastatic Cancer | Metastatic Melanoma

United States
National Cancer Institute (NCI)

Recruiting

Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

Small Cell Lung Cancer | Non-Small Cell Lung Cancer | Extrapulmonary Small Cell Cancer | Pulmonary Neuroendocrine Tumors | Thymic Epithelial Tumors

United States
Military Hospital 103
Nguyen Truong Giang

Completed

Relationship Between Computed Tomography Manifestation and Histopathological Classification of Thymic Epithelial Tumors

Thymoma
Beijing Konruns Pharmaceutical Co., Ltd.

Recruiting

A Study of KC1036 in Patients With Advanced Thymic Tumors

Thymic Tumors

China
Samsung Medical Center

Not yet recruiting

Rivoceranib in Patients With Metastatic Thymic Epithelial Tumor

Thymic Epithelial Tumor

Korea, Republic of
Shanghai Pulmonary Hospital, Shanghai, China

Recruiting

Clinical Study of Neoadjuvant PD-1 Antibody (Toripalimab) Plus Chemotherapy for Locally Advanced Thymic Epithelial Tumor

Thymic Epithelial Tumor

China
Samsung Medical Center

Recruiting

neoadjuvant_thymic Epithelial Tumor

Thymic Epithelial Tumor

Korea, Republic of
National Cancer Institute (NCI)

Terminated

Saracatinib in Treating Patients With Relapsed or Refractory Thymoma or Thymic Cancer

Invasive Thymoma and Thymic Carcinoma | Recurrent Thymoma and Thymic Carcinoma | Stage III Thymoma | Stage IVA Thymoma | Stage IVB Thymoma

United States
National Cancer Institute (NCI)

Terminated

A Phase 1/2 Study of PXD101 (Belinostat) in Combination With Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic, Malignancies

Thymic Carcinoma | Thymoma

United States
Hoffmann-La Roche

Active, not recruiting

A Study to Investigate the Efficacy and Safety of Atezolizumab (Tecentriq) in Previously-Treated Patients With Advanced Thymic Carcinoma

Carcinoma, Thymic

China
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Terminated

KN046 (a Humanized PD-L1/CTLA4 Bispecific Single Domain Fc Fusion Protein Antibody) in Subjects With Thymic Carcinoma

Thymic Carcinoma

China
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Carboplatin Combined With Paclitaxel in Treating Patients With Advanced Thymoma

Thymic Carcinoma | Thymoma

United States
Weill Medical College of Cornell University
Jiangsu Alphamab Biopharmaceuticals Co., Ltd

Terminated

A Study of KN046 in Patients With Thymic Carcinoma Who Failed Immune Checkpoint Inhibitors

Thymic Carcinoma

United States

Clinical Trials on Metastatic Thymic Neuroendocrine Neoplasm

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