Clinical Trials on Minimal Residual Disease

Total 380339 results

Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Stem Cell Transplant to Treat Patients With Favorable or Intermediate Risk Minimal Residual Disease Negative Acute Myeloid Leukemia

Acute Myeloid Leukemia | Minimal Residual Disease Negativity

United States
University of Leicester

Active, not recruiting

Minimal Residual Disease: A Trial Using Liquid Biopsies in Solid Malignancies. (MARTINI)

Cancer

United Kingdom
Institute of Hematology & Blood Diseases Hospital

Recruiting

Natural Killer(NK) Cell Therapy for AML Minimal Residual Disease

Minimal Residual Disease

China
Karolinska University Hospital
Medical University of Graz; Aarhus University Hospital; Centre Hospitalier Universitaire... and other collaborators

Enrolling by invitation

GUIDING MULTI-MODAL THERAPIES AGAINST MINIMAL RESIDUAL DISEASE BY LIQUID BIOPSIES (GUIDEMRD)

Pancreatic Adenocarcinoma

Sweden
University Hospital, Clermont-Ferrand

Unknown

Contamination of Testicle Tissue by RT-PCR in Participants With Solid Tumors (TESTIMAR)

Minimal Residual Disease | Fertility Preservation

France
Amgen

Terminated

A Phase 1 Study of AMG 330 in Subjects With Myeloid Malignancies

Myelodysplastic Syndrome | Relapsed/Refractory AML | Minimal Residual Disease Positive AML

United States, Canada, Germany, Netherlands
Nanfang Hospital of Southern Medical University

Unknown

HMA+DLI vs DLI Preemptive Therapy Based on MRD for AL Undergoing Allo-HSCT

Minimal Residual Disease,Acute Leukemia, Hypomethylating Agents, Donor Lymphocyte Infusion, Allogeneic Hematopoietic Cell Transplantation

China
University Hospital, Clermont-Ferrand

Unknown

Contamination of Ovarian Tissue by RT-PCR in Participants With Solid Tumors (OVAMAR)

Minimal Residual Disease | Fertility Preservation

France
Guangdong Provincial People's Hospital
Shenzhen Chipscreen Biosciences Co.Ltd

Recruiting

A Study of Chidamide With AZA in MRD Positive AML After Transplant

Minimal Residual Disease | AML, Adult

China
Xianmin Song, MD

Recruiting

Next Generation Sequencing（NGS）Monitors Minimal Residual Disease（MRD）in Allo-PBSCT Patients

NGS Monitor MRD

China
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

A Study of Olverembatinib Combined With Inotuzumab Ozogamicin in the Treatment ph+ ALL With MRD Persistent Positive

Minimal Residual Disease | Bone Marrow Transplant | Ph+ ALL

China
Centre Hospitalier Universitaire de Besancon
University Hospital, Rouen; Central Hospital, Nancy, France; University Hospital... and other collaborators

Completed

Validation of a Method to Search Residual Disease in Auto-cryopreserved Ovarian Tissues (VMRDO)

Minimal Residual Disease | Neoplastic Pathology | Cryopreserved Ovarian Tissue

France
Peking University People's Hospital

Unknown

Interferon α for the Therapy of Minimal Residual Disease

Leukemia

China
M.D. Anderson Cancer Center

Active, not recruiting

A PHASE IB STUDY OF IMMUNOTHERAPY WITH EX VIVO PRE-ACTIVATED AND EXPANDED CB-NK CELLS IN COMBINATION WITH CETUXIMAB, IN COLORECTAL CANCER PATIENTS WITH MINIMAL RESIDUAL DISEASE (MRD)

Colon Cancer | Resected Stage

United States
Centre Hospitalier Universitaire de Besancon
University Hospital, Rouen; CHU de Reims; Central Hospital, Nancy, France; University... and other collaborators

Completed

Investigating Minimal Residual Disease in Autopreserved Ovarian Tissue in Cases of Neoplastic Pathology (OVAGRAFT)

Neoplastic Pathology | Autopreserved Ovarian Tissue

France
WeiWei Xiao
Haplox Biotechnology Co., Ltd.

Recruiting

Predicting the Efficacy and Prognosis of Rectal Cancer Patients Based on ctDNA-MRD Technology

Minimal Residual Disease | Circulating Tumor DNA | Rectal Adenocarcinoma | Neoadjuvant Chemoradiotherapy

China
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Collection of Blood and Bone Marrow Samples From Select Patients With CML to Measure Minimal Residual Disease

Leukemia

United States
Gruppo Italiano Malattie EMatologiche dell'Adulto

Not yet recruiting

Kinetics and Impact on Survival of MRD in AML Patients Receiving Azacitidine and Venetoclax

Minimal Residual Disease | AML, Adult
Chinese PLA General Hospital

Unknown

Combined Inhibition of PD-1 and DNA Hypomethylating Agent +/- Chemotherapy in High-risk AML or Elderly Patients With AML Who Are Unfit for Intensive Chemotherapy

Acute Myeloid Leukemia, in Relapsed or Refractory | Acute Myeloid Leukemia, Elderly, Unfit | Acute Myeloid Leukemia With Positive Minimal Residual Disease

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Completed

MRD-directed Donor Lymphocyte Infusion for Reduce of Relapse After Allo-HSCT

Hematopoietic Stem Cell Transplantation | Minimal Residual Disease | Relapse | Donor Lymphocyte Infusion

China
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Phase I Study of Adoptive Immunotherapy With Enriched and Expanded Autologous Natural Killer (NK) Cells for Patients With Ph+ Acute Lymphoblastic Leukemia (ALL)

Acute Lymphoblastic Leukemia | Complete Hematologic Remission (CHR) | Persistent/Recurrent Minimal Residual Disease (MRD)

Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI); Genentech, Inc.

Recruiting

AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remission

Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Hematologic and Lymphocytic Disorder | Acute Myeloid Leukemia in Remission | FLT3 Gene Mutation | Minimal Residual Disease Persistence

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Genetic Test in Detecting Minimal Residual Disease in Samples From Younger Patients Registered on the COG-AALL08B1 Trial

Leukemia
University Hospital, Lille
Saint-Louis Hospital, Paris, France; Canceropôle Nord Ouest

Recruiting

Minimal Residual Disease Evaluation on Cryopreserved Ovarian Fragments in Younger Patients Treated for Acute Myeloid Leukemia (FERTILAM)

Acute Myeloid Leukemia

France
Abramson Cancer Center at Penn Medicine

Recruiting

ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer (ABBY)

Breast Cancer

United States
Shanghai iCELL Biotechnology Co., Ltd, Shanghai...
Hebei Yanda Ludaopei Hospital

Unknown

Natural Killer Cells Infusion for Treating Acute Myeloid Leukemia Patients With Minimal Residual Disease

Acute Myeloid Leukemia

China
Nanfang Hospital of Southern Medical University
Peking University People's Hospital; Guangzhou First People's Hospital; Sun Yat-Sen... and other collaborators

Completed

MRD-directed Therapy for Low-risk and Intermediate-risk AML.

Acute Myeloid Leukemia | Minimal Residual Disease

China
UNC Lineberger Comprehensive Cancer Center

Completed

Pilot Evaluation of a Microfluidic Assay to Detect Minimal Residual Disease and Predict Relapse in AML Patients

Acute Myeloid Leukemia

United States
University of Ulm

Terminated

Maintenance Therapy With Histamine Dihydrochloride and Interleukin-2 in Adult Acute Myeloid Leukemia (AML) Patients With Measurable Minimal Residual Disease (MRD)- a Non-interventional Study (NIS)

Acute Myeloid Leukemia

Germany
Institute of Hematology & Blood Diseases Hospital
Hangzhou Qihan Biotech Co.,Ltd.

Not yet recruiting

Natural Killer(NK) Cell Therapy in Acute Myeloid Leukemia

Minimal Residual Disease | AML, Adult

China
M.D. Anderson Cancer Center

Recruiting

Feasibility and Clinical Utility of Cell-free DNA (cfDNA) in Identifying Actionable Alterations and Minimal Residual Disease for Lymphoma Patients Across Community Centers in Texas

Lymphoma

United States
UNC Lineberger Comprehensive Cancer Center

Active, not recruiting

Development and Application of a Novel Digital Array PCR for Acute Myeloid Leukemia (AML)

Leukemia, Myeloid, Acute | Minimal Residual Disease

United States
Memorial Sloan Kettering Cancer Center
Pfizer

Withdrawn

Safety and Clinical Activity Study of Combination Azacitidine and Avelumab in Patients With Acute Myeloid Leukemia (AML) and Minimal Residual Disease (MRD)

Acute Myeloid Leukemia (AML) | Minimal Residual Disease

United States
Nanfang Hospital of Southern Medical University
Guangzhou First People's Hospital; Second Affiliated Hospital, Sun Yat-Sen... and other collaborators

Unknown

The Effect of G-CSF on MRD After Induction Therapy in Newly Diagnosed AML

Acute Myeloid Leukemia | Minimal Residual Disease | Granulocyte Colony-stimulating Factor

China
University Medical Center Ho Chi Minh City (UMC)

Recruiting

Monitoring Minimal Residual Disease in Gastric Cancer by Liquid Biopsy Study Description

Gastric Cancer | ctDNA

Vietnam
Exact Sciences Corporation
Labcorp Corporation of America Holdings, Inc

Recruiting

First CORRECT Study of Minimal Residual Disease (MRD) Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United Kingdom, Spain, Italy, Israel
Enterome

Completed

EO2040 in Combination With Nivolumab, for Treatment of Patients With Minimal Residual Disease of Colorectal Cancer (CLAUDE)

Colorectal Cancer

United States
Gruppo Oncologico del Nord-Ovest

Not yet recruiting

Adjuvant TRastuzumab Deruxtecan for HER2-positive Gastroesophageal Cancer With Persistence of miNImal Residual Disease (TRINITY)

Gastric Cancer | HER2-positive Gastric Cancer

Italy
University of Jena
Ludwig-Maximilians - University of Munich

Terminated

Midostaurin in MRD (Minimal Residual Disease) Positive Acute Myeloid Leukemia After Allogeneic Stem Cell Transplantation

Acute Myeloid Leukemia, Adult

Germany
University of Leipzig
Millennium Pharmaceuticals, Inc.

Completed

Treatment of MDS/AML Patients With an Impending Hematological Relapse With AZA or ATA and Pevonedistat

Myelodysplastic Syndromes | Minimal Residual Disease | Acute Myeloid Leukemia in Remission

Germany
RenJi Hospital
Peking University First Hospital; Xiangya Hospital of Central South University and other collaborators

Recruiting

Circulating Tumour DNA and Urine Tumor DNA Detection of Minimal Residual Disease in Locally Advanced Upper Tract Urothelial Carcinoma With Radical Nephroureterectomy: A Cohort Study

Muscle Invasive Upper Tract Urothelial Carcinoma

China
Federico II University

Recruiting

Cell-free Tumor DNA as Minimal Residual Disease in Hodgkin Lymphoma Patients

Hodgkin Lymphoma

Italy
M.D. Anderson Cancer Center
Bellicum Pharmaceuticals, Inc.

Not yet recruiting

Dose Escalation and Expansion Study of TROP2 CAR Engineered IL-15- Transduced Cord Blood-derived NK Cells in Combination With Cetuximab in Patient With Colorectal Cancer (CRC) With Minimal Residual Disease (MRD)

Colorectal Cancer | Minimal Residual Disease

United States
Exact Sciences Corporation
NSABP Foundation Inc

Recruiting

CORRECT Study of Minimal Residual Disease Detection in Colorectal Cancer (MRD)

Colorectal Cancer

United States
Fudan University
Shanghai Weihe Medical Laboratory Co., Ltd.

Not yet recruiting

Assessment of Early Pancreatic Cancer Prognosis by Minimal Residual Disease Using Multi-omics Approach

Pancreatic Ductal Adenocarcinoma

China
Centre Henri Becquerel
U918 ( Inserm unit)

Completed

Assessment of the Minimal Residual Disease in DLBCL From Cell-free Circulating DNA by NGS (LymphoSeq)

Non Hodgkin Lymphoma

France
Personalis Inc.

Recruiting

ctDNA Based MRD Testing for NAC Monitoring in TNBC (B-STRONGER-I)

Minimal Residual Disease | TNBC - Triple-Negative Breast Cancer

United States
University of Florida
Celgene Corporation

Terminated

Lenalidomide After Allo-Hematopoietic Cell Transplant (HCT) in Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndromes (MDS) Subjects With Minimal Residual Disease (UF-BMT-MRD-101)

Myelodysplastic Syndromes | Leukemia, Myeloid

United States
M.D. Anderson Cancer Center

Recruiting

DAILY: Vitamin D, Aspirin, ExercIse, Low Saturated Fat Foods StudY in Colorectal Cancer Patients With Minimal Residual Disease

Colorectal Cancer | Colon Cancer

United States
Qilu Hospital of Shandong University
The Affiliated Hospital of Qingdao University; Shandong Provincial Hospital; Jinan... and other collaborators

Recruiting

Minimal Residual Disease-guided Adjuvant Therapy for Gastric Cancer

Stage II-III Gastric Cancer

China

Clinical Trials on Minimal Residual Disease

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Sweden

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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