Clinical Trials on Mismatch Repair-deficient (dMMR) in Canada
Total 17 results
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The Hospital for Sick ChildrenBristol-Myers SquibbTerminatedRefractory or Recurrent Hypermutated Malignancies | Biallelic Mismatch Repair Deficiency (bMMRD) Positive PatientsUnited States, France, Canada, Australia, Israel
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Bristol-Myers SquibbActive, not recruitingMicrosatellite Stable Colorectal Cancer | Mismatch Repair Proficient Colorectal Cancer | Microsatellite Unstable Colorectal Cancer | Mismatch Repair Deficient Colorectal CancerUnited States, Australia, Belgium, Canada, Ireland, Italy, Spain, France
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University Health Network, TorontoAstraZenecaActive, not recruitingPancreatic Adenocarcinoma | Leiomyosarcoma | Mismatch Repair Proficient Colorectal CancerCanada
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Incyte CorporationRecruitingMelanoma | Hepatocellular Carcinoma (HCC) | Renal Cell Carcinoma (RCC) | Colorectal Carcinoma (CRC) | Microsatellite Instability - High (MSI-H) | Mismatch Repair Deficient (dMMR)United States, Canada, South Africa, Mexico
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The Hospital for Sick ChildrenEnrolling by invitation
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Acasti Pharma Inc.Active, not recruitingAtaxia TelangiectasiaCanada
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National Cancer Institute (NCI)RecruitingLynch Syndrome | Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Refractory Ependymoma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Refractory Diffuse Intrinsic Pontine Glioma | Recurrent Brain Neoplasm | Refractory Brain Neoplasm | Constitutional...United States, Canada
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National Cancer Institute (NCI)WithdrawnHematopoietic and Lymphoid Cell Neoplasm | Lynch Syndrome | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central... and other conditionsUnited States, Canada
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Tampere University HospitalTampere UniversityRecruitingLynch Syndrome | Urothelial CarcinomaCanada, Finland
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National Institute of Allergy and Infectious Diseases...National Center for Advancing Translational Sciences (NCATS); Primary Immune...Enrolling by invitationADA-SCID | Omenn Syndrome | SCID | Reticular Dysgenesis | XSCID | Leaky SCIDUnited States, Canada
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Shattuck Labs, Inc.Active, not recruitingMelanoma | Renal Cell Carcinoma | Hodgkin Lymphoma | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Diffuse Large B Cell Lymphoma | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Squamous Cell Carcinoma of the Skin | Squamous Cell Carcinoma... and other conditionsUnited States, Canada, Belgium, Spain
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National Institute of Allergy and Infectious Diseases...National Center for Advancing Translational Sciences (NCATS); Office of Rare... and other collaboratorsEnrolling by invitationOmenn Syndrome | Reticular Dysgenesis | Severe Combined Immunodeficiency (SCID) | XSCID | Leaky SCID | ADA SCIDUnited States, Canada
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Grifols Therapeutics LLCCompletedCommon Variable Immunodeficiency | Severe Combined Immunodeficiency | Wiskott-Aldrich Syndrome | Agammaglobulinemia | Immunologic Deficiency SyndromeCanada, United States
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University Health Network, TorontoSunnybrook Health Sciences Centre; University of Toronto; Hamilton Health Sciences... and other collaboratorsActive, not recruitingUniversal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer (LS2)Colorectal Neoplasms | Ovarian Neoplasms | Lynch Syndrome | Endometrial NeoplasmsCanada
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University Health Network, TorontoRecruitingMelanoma | Lymphoma | Kidney Cancer | Leukemia | Cancer | Breast Cancer | Head and Neck Cancer | Ovarian Cancer | Lynch Syndrome | Lung Cancer | Colon Cancer | Meningioma | BRCA1 Mutation | BRCA2 Mutation | Myeloma | Mutation | Uterine Cancer | Cowden SyndromeCanada
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Gilead SciencesCompletedHIV Infections | Renal Impairment | Fanconi Syndrome | Kidney DiseaseCanada, United States
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National Cancer Institute (NCI)Active, not recruitingLynch Syndrome | Colon Mucinous Adenocarcinoma | Colon Signet Ring Cell Adenocarcinoma | Stage IIA Colon Cancer AJCC v7 | Stage IIB Colon Cancer AJCC v7 | Stage IIC Colon Cancer AJCC v7United States, Canada, Puerto Rico, Peru, South Africa