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Clinical Trials on Mismatch Repair Protein Proficient
Total 59 results
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Yu jirenRecruitingAdenocarcinoma of the Stomach | Adenocarcinoma of Esophagogastric Junction | Proficient Mismatch RepairChina
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Bristol-Myers SquibbActive, not recruitingMicrosatellite Stable Colorectal Cancer | Mismatch Repair Proficient Colorectal Cancer | Microsatellite Unstable Colorectal Cancer | Mismatch Repair Deficient Colorectal CancerUnited States, Australia, Belgium, Canada, Ireland, Italy, Spain, France
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Rottapharm BiotechAgenus Inc.Active, not recruitingSolid Tumor | Metastatic Microsatellite-stable Colorectal Cancer | Mismatch Repair Protein Proficient | Refractory Metastatic Colorectal CancerItaly
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University Health Network, TorontoAstraZenecaActive, not recruitingPancreatic Adenocarcinoma | Leiomyosarcoma | Mismatch Repair Proficient Colorectal CancerCanada
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The Hospital for Sick ChildrenBristol-Myers SquibbTerminatedRefractory or Recurrent Hypermutated Malignancies | Biallelic Mismatch Repair Deficiency (bMMRD) Positive PatientsUnited States, France, Canada, Australia, Israel
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BeiGeneRecruitingUnresectable or Metastatic Microsatellite Stable/Mismatch Repair Proficient Colorectal CancerChina, United States, Australia, Puerto Rico
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Zhejiang Cancer HospitalRecruitingColorectal Cancer Metastatic | Microsatellite Stable | Mismatch Repair-proficientChina
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University of California, San FranciscoMerck Sharp & Dohme LLCCompletedStage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Microsatellite Stable | Stage III Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer AJCC v7 | Mismatch Repair Protein ProficientUnited States
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Virginia Commonwealth UniversityActive, not recruitingEndometrial Cancer | Recurrent Endometrial Cancer | Mismatch Repair-ProficientUnited States
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Assistance Publique - Hôpitaux de ParisNot yet recruiting
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Yu jirenRecruitingAdenocarcinoma of the Stomach | Mismatch Repair Deficiency | Adenocarcinoma of Esophagogastric JunctionChina
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Apollomics (Australia) Pty. Ltd.Novotech (Australia) Pty Limited; Apollomics Inc. (formerly CBT Pharmaceuticals...CompletedSolid Tumor | Microsatellite Instability | Mismatch Repair Deficiency | Cancer of Unknown Primary SiteAustralia
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Syndax PharmaceuticalsMerck Sharp & Dohme LLCCompletedMelanoma | Non-Small Cell Lung Cancer | Mismatch Repair-Proficient Colorectal CancerUnited States
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Peking Union Medical College HospitalRecruitingColon Cancer | Immunotherapy | Mismatch Repair DeficiencyChina
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Roswell Park Cancer InstituteMerck Sharp & Dohme LLCWithdrawnMetastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Microsatellite Stable | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA... and other conditionsUnited States
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National Cancer Institute (NCI)WithdrawnAdvanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Multiple Myeloma
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VA Office of Research and DevelopmentMerck Sharp & Dohme LLCRecruitingMetastatic Castration Resistant Prostate CancerUnited States
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National Cancer Institute (NCI)CompletedHematopoietic and Lymphoid Cell Neoplasm | Advanced Lymphoma | Advanced Malignant Solid Neoplasm | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Refractory Plasma Cell MyelomaUnited States
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Third Affiliated Hospital, Sun Yat-Sen UniversityRecruitingColorectal Cancer | Neoadjuvant Therapy | Mismatch Repair-deficient (dMMR) | Microsatellite Instability-high (MSI-H)China
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Sun Yat-sen UniversityRecruitingColorectal Cancer | Neoadjuvant Therapy | Mismatch Repair-deficient (dMMR) | Microsatellite Instability-high (MSI-H)China
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Sun Yat-sen UniversityThe Second Affiliated Hospital of Kunming Medical UniversityCompletedColorectal Cancer Metastatic | Microsatellite Instability High | Mismatch Repair DeficiencyChina
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LiuYingNot yet recruitingColorectal Cancer | Neoadjuvant Therapy | Mismatch Repair-deficient (dMMR) | Microsatellite Instability-high (MSI-H)China
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Sun Yat-sen UniversityRecruitingColorectal Cancer Stage IV | Mismatch Repair-deficient (dMMR) | Microsatellite Instability-high (MSI-H)China
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University of Colorado, DenverNational Cancer Institute (NCI); Cancer League of ColoradoWithdrawnColorectal Cancer | Microsatellite Instability High | Mismatch Repair DeficiencyUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedHigh-Frequency Microsatellite Instability | Mismatch Repair Gene Mutation | Mutation-Negative Lynch Syndrome | Mutation-Positive Lynch SyndromeUnited States
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Rutgers, The State University of New JerseyNational Cancer Institute (NCI)RecruitingGastric Adenocarcinoma | Epstein-Barr Virus Positive | Mismatch Repair Protein Deficiency | Stage IB Gastric Cancer AJCC v7 | Stage II Gastric Cancer AJCC v7 | Stage IIA Gastric Cancer AJCC v7 | Stage IIB Gastric Cancer AJCC v7 | Stage III Gastric Cancer AJCC v7 | Stage IIIA Gastric Cancer AJCC v7 | Stage... and other conditionsUnited States
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Replimune Inc.RecruitingCancer | NSCLC | Melanoma (Skin) | Microsatellite Instability | Cutaneous Melanoma | Mismatch Repair Deficiency | Non-melanoma Skin CancerUnited States, Spain, France, United Kingdom, Germany
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WellSpan HealthActive, not recruitingEndometrial Hyperplasia | Lynch Syndrome | Endometrial Cancer | Microsatellite Instability | Mismatch Repair DeficiencyUnited States
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Medical University InnsbruckUnknown
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Floor BackesTerminatedLynch Syndrome | Recurrent Endometrial Carcinoma | Recurrent Endometrial Clear Cell Adenocarcinoma | Recurrent Endometrial Cancer | Metastatic Endometrial Cancer | Mismatch Repair Deficiency | Recurrent Uterine Corpus CarcinosarcomaUnited States
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Udai KammulaRecruitingSarcoma | Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Neuroendocrine Tumors | Mesothelioma | Merkel Cell Carcinoma | Microsatellite Instability | Squamous Cell Cancer | Mismatch Repair DeficiencyUnited States
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National Human Genome Research Institute (NHGRI)Withdrawn
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Neonc Technologies, Inc.RecruitingMelanoma | Renal Cell Carcinoma | Cervical Cancer | Small Cell Lung Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Merkel Cell Carcinoma | Gastroesophageal Junction... and other conditionsUnited States
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National Cancer Institute (NCI)RecruitingLynch Syndrome | Malignant Glioma | Recurrent Childhood Ependymoma | Recurrent Medulloblastoma | Refractory Ependymoma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Refractory Diffuse Intrinsic Pontine Glioma | Recurrent Brain Neoplasm | Refractory Brain Neoplasm | Constitutional...United States, Canada
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Incyte CorporationRecruitingMelanoma | Hepatocellular Carcinoma (HCC) | Renal Cell Carcinoma (RCC) | Colorectal Carcinoma (CRC) | Microsatellite Instability - High (MSI-H) | Mismatch Repair Deficient (dMMR)United States, Canada, South Africa, Mexico
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National Cancer Institute (NCI)WithdrawnHematopoietic and Lymphoid Cell Neoplasm | Lynch Syndrome | Refractory Lymphoma | Refractory Malignant Solid Neoplasm | Recurrent Lymphoma | Recurrent Malignant Solid Neoplasm | Recurrent Neuroblastoma | Refractory Neuroblastoma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary Central... and other conditionsUnited States, Canada
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Grifols Therapeutics LLCCompletedCommon Variable Immunodeficiency | Severe Combined Immunodeficiency | Wiskott-Aldrich Syndrome | Agammaglobulinemia | Immunologic Deficiency SyndromeCanada, United States
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SynthekineRecruitingRenal Cell Carcinoma | Cervical Cancer | Gastric Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Microsatellite Instability High | Malignant Melanoma | GastroEsophageal Cancer | Mismatch Repair DeficiencyUnited States
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7 Hills Pharma, LLCRecruitingMelanoma | Kidney Cancer | Renal Cell Carcinoma | Hepatocellular Carcinoma | Colorectal Cancer | NSCLC | Non Small Cell Lung Cancer | Skin Cancer | Metastasis | Advanced Solid Tumor | Advanced Cancer | Renal Cell Cancer | Hepatocellular Cancer | Mismatch Repair Deficiency | Pleural Mesothelioma | MSI-High | Anaplastic Lymphoma... and other conditionsUnited States
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Molecular Templates, Inc.RecruitingMelanoma | Renal Cell Carcinoma | Cervical Cancer | Hepatocellular Carcinoma | Non Small Cell Lung Cancer | Mesothelioma | Squamous Cell Carcinoma of Head and Neck | Esophageal Squamous Cell Carcinoma | Urothelial Carcinoma | Microsatellite Instability High | Mismatch Repair DeficiencyUnited States
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Shattuck Labs, Inc.CompletedMelanoma | Renal Cell Carcinoma | Hodgkin Lymphoma | Gastric Adenocarcinoma | Non Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck | Diffuse Large B Cell Lymphoma | Urothelial Carcinoma | Gastroesophageal Junction Adenocarcinoma | Squamous Cell Carcinoma of the Skin | Squamous Cell Carcinoma... and other conditionsUnited States, Canada, Belgium, Spain
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Incyte CorporationCompletedMelanoma | Renal Cell Carcinoma | Cervical Cancer | Stomach Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Esophageal Cancer | Ovarian Cancer | NSCLC | Mesothelioma | Squamous Cell Carcinoma of the Head and Neck | Non-small Cell Lung Cancer | Gastroesophageal Junction Cancer | Urothelial... and other conditionsUnited States
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OHSU Knight Cancer InstituteNational Heart, Lung, and Blood Institute (NHLBI)CompletedChronic Myeloproliferative Disorders | Fanconi Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative NeoplasmsUnited States
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Roswell Park Cancer InstituteCompletedLymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Fanconi Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Aplastic AnemiaUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); AstraZenecaActive, not recruitingStage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC... and other conditionsUnited States
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Masonic Cancer Center, University of MinnesotaNational Cancer Institute (NCI)TerminatedLymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Fanconi Anemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease | Diamond-blackfan AnemiaUnited States
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ImmunityBio, Inc.Active, not recruitingMelanoma | Renal Cell Carcinoma | Cervical Cancer | Small Cell Lung Cancer | Hepatocellular Carcinoma | Gastric Cancer | Colorectal Cancer | Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Merkel Cell Carcinoma | Microsatellite Instability | Mismatch Repair DeficiencyUnited States
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Masonic Cancer Center, University of MinnesotaRecruitingCommon Variable Immunodeficiency | Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | X-linked Lymphoproliferative Disease | Langerhan's Cell Histiocytosis | Chediak-Higashi Syndrome | Griscelli Syndrome | Bare Lymphocyte Syndrome | SCID | Omenn's Syndrome | Reticular... and other conditionsUnited States
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Fairview University Medical CenterTerminatedImmunologic Deficiency Syndromes | Common Variable Immunodeficiency | Severe Combined Immunodeficiency | Chronic Granulomatous Disease | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | Graft Versus Host Disease | X-linked Agammaglobulinemia | Chediak-Higashi Syndrome | Virus-Associated... and other conditionsUnited States
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Washington University School of MedicineRecruitingSevere Combined Immunodeficiency | Chronic Granulomatous Disease | DiGeorge Syndrome | Hemophagocytic Lymphohistiocytosis | Wiskott-Aldrich Syndrome | X-linked Lymphoproliferative Syndrome | X-linked Agammaglobulinemia | Chediak-Higashi Syndrome | IPEX | Autoimmune Lymphoproliferative Syndrome | Common Variable... and other conditionsUnited States