Clinical Trials on Mitral Valve Insufficiency in Singapore

Total 214 results

Singapore General Hospital

Completed

Impact of Social Distancing on Bariatric Versus Non-Surgical Obese Patients During COVID-19 Pandemic

Diabetes Mellitus, Type 2 | Obesity, Morbid | Bariatric Surgery Candidate

Singapore
GREAT Network Italy

Completed

Biomarker Rule in/Out in Patients With Acute Diseases for Validation of AKI (BRAVA) Acute Kidney Injury (BRAVA)

Acute Kidney Injury

Korea, Republic of, Singapore, Australia, India, Thailand
KK Women's and Children's Hospital
Duke-NUS Graduate Medical School

Recruiting

Determining Reactogenicity and Immunogenicity of Delayed COVID-19 Vaccine Schedule in Children

COVID-19 | Vaccine Reaction | Children, Only

Singapore
Tan Tock Seng Hospital
National University Hospital, Singapore; University of Malaya; Singapore General... and other collaborators

Completed

Adult Dengue Platelet Study (ADEPT)

Dengue Fever

Malaysia, Singapore
Mina Alpha Limited

Active, not recruiting

Radomised Phase II Study of MTL-CEBPA Plus Sorafenib or Sorafenib Alone (OUTREACH2)

Hepatitis B | Hepatocellular Carcinoma | Hepatitis C

Singapore, United States
Novo Nordisk A/S

Completed

Growth Hormone Treatment in Adult Patients With Chronic Kidney Disease

Chronic Kidney Disease | End-Stage Renal Disease

Poland, Israel, United Kingdom, Germany, Denmark, Singapore, Switzerland, Hong Kong, Sweden
Hellenic Cooperative Oncology Group
Emory University; Fondazione IRCCS Istituto Nazionale dei Tumori, Milano; University... and other collaborators

Recruiting

Head and Neck cancERs International cOviD-19 collabOraTion

Head and Neck Cancer | Covid19

Greece, Italy, Singapore
Novartis
Novartis Pharmaceuticals

Completed

Telbivudine Versus the Combination of Telbivudine and Valtorcitabine in Patients With Chronic Hepatitis B

Hepatitis B

Hong Kong, Singapore, New Zealand
Novartis Pharmaceuticals

Completed

Safety and Tolerability of Valsartan in Children 6 to 17 Years of Age

Hypertension | Chronic Kidney Disease

Colombia, Russian Federation, Singapore, Germany, Guatemala, Korea, Republic of, Finland, Philippines, Romania, Poland
Arcturus Therapeutics, Inc.

Recruiting

A Trial Evaluating the Safety and Immunogenicity of 3 COVID-19 SARS-CoV-2 RNA Vaccines in Healthy Adults

COVID-19 | Corona Virus Infection | SARS-CoV-2 Infection

United States, Singapore
SCG Cell Therapy Pte. Ltd.

Recruiting

A Study of SCG101 in the Treatment of Subjects With Hepatitis B Virus-Related Hepatocellular Carcinoma (TCR-T)

Hepatocellular Carcinoma Recurrent | Hepatitis B Virus Related Hepatocellular Carcinoma

United States, Singapore, Hong Kong
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety Study of MCI-196 Versus Simvastatin for Dyslipidaemia in Chronic Kidney Disease (CKD) Subjects on Dialysis

Chronic Kidney Disease

Belarus, Bulgaria, Romania, Malaysia, Singapore, Thailand, Italy, Lithuania, Latvia, Croatia, Denmark, Israel, Indonesia
Medtronic - MITG

Completed

PRediction of Opioid-induced Respiratory Depression In Patients Monitored by capnoGraphY (PRODIGY)

Respiratory Depression

United States, Japan, Spain, Singapore, Germany, Netherlands, France
Takeda

Completed

Study to Investigate the Safety and Immunogenicity of a Tetravalent Chimeric Dengue Vaccine in Healthy Volunteers Between the Ages of 1.5 - 45 Years

Healthy

Colombia, Singapore, Thailand, Puerto Rico
Hoffmann-La Roche

Completed

A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or Both

Hepatitis B, Chronic

Taiwan, United States, New Zealand, Singapore
Hoffmann-La Roche

Completed

A Study of Pegasys Monotherapy in Patients With Chronic Hepatitis B Who Have Participated in Previous Studies

Hepatitis B, Chronic

Taiwan, United States, New Zealand, Singapore
The University of Queensland
Tan Tock Seng Hospital; University of North Carolina, Chapel Hill; Royal Brisbane... and other collaborators

Completed

Risks of Bacterial and Fungal Superinfection in Patients With COVID-19

COVID-19

Thailand, United States, Australia, Singapore, India
Janssen Research & Development, LLC

Terminated

A Long Term Follow-up Study in Participants Treated in a Preceding Phase 2 or 3 Study With a Regimen Containing Odalasvir and AL-335 With or Without Simeprevir for the Treatment of Hepatitis C Virus (HCV) Infection

Hepatitis C

Singapore, Canada, Poland, New Zealand
Novartis Pharmaceuticals

Active, not recruiting

A Study to Assess the Efficacy, Safety and Pharmacokinetics of EYU688 in Patients With Dengue Fever

Dengue

Singapore, Malaysia, India
Samsung Medical Center

Completed

Factors Influencing Hepatitis B Virus Reactivation in Lymphoma Patients Treated With Rituximab

Patients With Diffuse Large B-cell Lymphoma or Follicular Lymphoma | Patients Treated With Rituximab-CHOP or Rituximab-CVP

Korea, Republic of, Malaysia, Singapore, China
PowderMed

Completed

Safety Study of HBV DNA Vaccine to Treat Patients With Chronic Hepatitis B Infection

Chronic Hepatitis B

Thailand, Hong Kong, Singapore, Taiwan
Triangle Pharmaceuticals

Unknown

A Safety Study to Evaluate 12 Weeks of Treatment with Clevudine in Patients Infected with Hepatitis B Virus.

Hepatitis B

United States, Canada, China, France, Singapore
Al-Azhar University
Helwan University; National Liver Institute, Egypt

Completed

Advanced Endoscopy During COVID-19

COVID-19 | Cholangiocarcinoma | SARS-CoV-2 | Pancreas Cancer | Obstructive Jaundice | Cholangitis, Secondary Biliary

Singapore, Germany, United States, Egypt, Peru
McMaster University
Canadian Institutes of Health Research (CIHR)

Completed

Nasal Intermittent Positive Pressure Ventilation in Premature Infants (NIPPV) (NIPPV)

Respiratory Insufficiency of Prematurity

United States, Singapore, United Kingdom, Canada, Ireland, Qatar, Austria, Belgium, Netherlands, Sweden
Assembly Biosciences

Completed

A Study to Assess the Safety, Pharmacokinetics, and Antiviral Activity of ABI-H3733 in Subjects With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Singapore, Hong Kong, Bulgaria, Moldova, Republic of, New Zealand, Romania
Hoffmann-La Roche

Completed

A Study to Assess All-Cause Mortality and Cardiovascular Morbidity in Participants With Chronic Kidney Disease (CKD) on Dialysis and Those Not on Renal Replacement Therapy Receiving Methoxy Polyethylene Glycol-Epoetin Beta (Mircera) or Reference Erythropoietin Stimulating Agents (ESAs)

Chronic Renal Anemia

Belgium, Brazil, United Kingdom, Serbia, Spain, Germany, Korea, Republic of, Turkey, Lithuania, Italy, Czechia, Argentina, Australia, Croatia, France, Greece, Israel, Malaysia, Mexico, Panama, Philippines, Poland, Russian Federation, ... and more
FibroGen
AstraZeneca; Astellas Pharma Europe B.V.

Completed

A Study of Roxadustat for the Treatment of Anemia in Participants With Chronic Kidney Disease and Not Receiving Dialysis

CKD Anemia

United States, Australia, Thailand, Korea, Republic of, Malaysia, Mexico, Taiwan, New Zealand, Argentina, Chile, Colombia, Hong Kong, Peru, Philippines, Puerto Rico, Singapore
Children's Hospital Medical Center, Cincinnati

Completed

Observational Study of Pediatric Acute Kidney Injury, Risk Factors and Outcomes (AWARE)

Acute Kidney Injury

United States, Serbia, Korea, Republic of, Italy, Australia, Canada, China, Indonesia, Singapore, United Kingdom
Alnylam Pharmaceuticals

Terminated

A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B | Chronic Hepatitis B | Hepatitis B, Chronic | HBV | Hepatitis B Infection

United Kingdom, New Zealand, Singapore, Korea, Republic of, Australia, Hong Kong
Tricida, Inc.

Terminated

Evaluation of Effect of TRC101 on Progression of Chronic Kidney Disease in Subjects With Metabolic Acidosis (VALOR-CKD)

Chronic Kidney Disease | Metabolic Acidosis

United States, Albania, Argentina, Armenia, Australia, Belarus, Belgium, Brazil, Bulgaria, Canada, Chile, Colombia, Czechia, France, Georgia, Hong Kong, Hungary, Israel, Italy, Korea, Republic of, Malaysia, Mexico, Netherlands, North... and more
Novira Therapeutics, Inc.

Completed

Dose-Ranging Study to Assess the Safety, PK and Initial Antiviral Efficacy of NVR 3-778 in Chronic HBV Patients

Chronic Hepatitis B

United States, Taiwan, Singapore, Korea, Republic of, China
Veloxis Pharmaceuticals

Completed

Double-Blind,Double-Dummy,Efficacy/Safety,LCP-Tacro™ Vs Prograf®,Prevention Rejection,De Novo Adult Kidney Tx (LCPTacro3002)

Renal Failure

United States, Argentina, Australia, Brazil, France, Germany, Italy, Korea, Republic of, Mexico, New Zealand, Poland, Serbia, Singapore, Spain, Sweden
Amgen

Recruiting

A Study of Etelcalcetide in Pediatric Subjects With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis

Chronic Kidney Disease | Secondary Hyperparathyroidism

Korea, Republic of, United States, India, Singapore, Taiwan, Argentina, Malaysia, Russian Federation, Turkey, Ukraine
Hoffmann-La Roche

Completed

A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infection

Hepatitis B, Chronic

Korea, Republic of, Taiwan, Hong Kong, Malaysia, Singapore, New Zealand
GlaxoSmithKline

Completed

Adefovir Dipivoxil For The Treatment Of Patients With Chronic Hepatitis B Related Advanced Fibrosis Or Cirrhosis

Fibrosis | Chronic Hepatitis B | Hepatitis B, Chronic | Cirrhosis

Taiwan, Korea, Republic of, Singapore, Hong Kong, Vietnam
Novartis Pharmaceuticals

Completed

Advancing Renal TRANSplant eFficacy and Safety Outcomes With an eveRolimus-based regiMen (TRANSFORM) (TRANSFORM)

Hemodialysis | Renal Replacement Therapy | End Stage Renal Disease (ESRD) | Renal Transplantation | Chronic Kidney Disease (CKD)

Germany, United States, Belgium, Italy, Spain, Croatia, Taiwan, Australia, Austria, Greece, Korea, Republic of, Lebanon, Czechia, Israel, Netherlands, Slovenia, Switzerland, Thailand, Norway, Turkey, Sweden, Argentina, Brazil, Japan, Se... and more
The George Institute
Bayer; King Abdullah International Medical Research Center; George Clinical Pty... and other collaborators

Recruiting

Treatment of Cardiovascular Disease With Low Dose Rivaroxaban in Advanced Chronic Kidney Disease (TRACK)

Cardiovascular Disease | Chronic Kidney Diseases | Dialysis-dependent Kidney Failure

Taiwan, Australia, Malaysia, Tunisia, Singapore, Canada, France, India, Saudi Arabia
Novartis Pharmaceuticals

Recruiting

A Multi-center Study to Evaluate the Safety, Tolerability and Efficacy of TIN816 in Patients at Risk for Acute Kidney Injury Following Cardiac Surgery.

Acute Kidney Injury Following Cardiac Surgery

France, Taiwan, Belgium, Germany, Argentina, Spain, Czechia, Hungary, Singapore, Estonia, Brazil, Lithuania
Pfizer

Terminated

Safety And Efficacy Of Oral PF-4136309 In Patients With Chronic Hepatitis C Infection And Abnormal Liver Enzymes

Hepatitis C, Chronic

Taiwan, Singapore, India, Korea, Republic of, Hong Kong
GlaxoSmithKline

Completed

A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3389404 in Chronic Hepatitis B (CHB) Subjects

Hepatitis B

Singapore, China, Hong Kong, Japan, Korea, Republic of, Philippines
Sanofi Pasteur, a Sanofi Company

Active, not recruiting

Study on an Investigational Yellow Fever Vaccine Compared With Stamaril in Adults in Europe and Asia

Yellow Fever

Germany, France, Finland, Singapore, Spain, Thailand
Vir Biotechnology, Inc.

Completed

Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection

Chronic Hepatitis B

Germany, Hong Kong, Korea, Republic of, New Zealand, Romania, Singapore, United Kingdom
Alexion

Completed

Copper Concentration & Histopathologic Changes in Liver Biopsy in Participants With Wilson Disease Treated With ALXN1840

Wilson Disease

United Kingdom, New Zealand, United States, Denmark, Russian Federation, Spain, Singapore
University of Social Sciences and Humanities, Warsaw

Completed

Health Behavior Change During COVID-19 Pandemic

Health Behavior

China, Italy, Switzerland, Israel, Germany, France, Australia, Canada, Gambia, Malaysia, Poland, Portugal, Romania, Singapore
Arcturus Therapeutics, Inc.

Terminated

A Trial Evaluating the Safety and Effects of an RNA Vaccine ARCT-021 in Healthy Adults

Covid19 | Corona Virus Infection | SARS-CoV Infection

United States, Singapore
Bayer

Recruiting

A Study Called FINE-REAL to Learn More About the Use of the Drug Finerenone in a Routine Medical Care Setting

Type 2 Diabetes Mellitus | Chronic Kidney Disease

United States, Germany, Argentina, Belgium, Brazil, Canada, Chile, Colombia, France, Italy, Korea, Republic of, Luxembourg, Mexico, Netherlands, Russian Federation, Saudi Arabia, Singapore, Slovenia, Spain, Switzerland, Taiwan, Th... and more
Novartis
Novartis Pharmaceuticals

Completed

Telbivudine Versus Adefovir Dipivoxil in Adults With HBegAg-Positive, Compensated Chronic Hepatitis B

Chronic Hepatitis B

Australia, Canada, France, United States, Taiwan, Korea, Republic of, Singapore, Thailand, China
Bayer

Active, not recruiting

A Trial to Learn How Well Finerenone Works and How Safe it is in Adult Participants With Non-diabetic Chronic Kidney Disease (FIND-CKD)

Non-diabetic Chronic Kidney Disease

Hong Kong, United States, Spain, China, Belgium, Taiwan, Australia, Korea, Republic of, Russian Federation, United Kingdom, Singapore, Malaysia, Japan, Greece, Israel, Hungary, Italy, Czechia, Denmark, Argentina, Bulgaria, Mexico, I... and more
GlaxoSmithKline

Recruiting

A Study of Belantamab Mafodotin Monotherapy in Multiple Myeloma Participants With Normal and Varying Degree of Impaired Renal Function (DREAMM12)

Multiple Myeloma

United States, Greece, Korea, Republic of, Singapore
Hoffmann-La Roche

Completed

A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected Participants

Hepatitis B, Chronic

Australia, New Zealand, Singapore, Thailand, Taiwan, China, Bulgaria, Hong Kong

Clinical Trials on Mitral Valve Insufficiency in Singapore

Sponsors and Collaborators

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CROs in Russia

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