Clinical Trials on Moderate and Severe COVID-19

Total 11848 results

Cellex, Inc.
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Clinical Evaluation of QFlu Combo Test (QFlu)

Fatigue | Myalgia | Cough | Fever | Headache | Nasal Obstruction | Sore Throat

United States
University of Pisa

Unknown

Study on the Incidence of Febrile Episodes During Stem Cells Collection After Chemotherapy in Patients With Multiple Myeloma

G-CSF, Multiple Myeloma, Febrile Episode, Filgrastim, Leograstim
Poitiers University Hospital

Completed

Efficacy of Antibiotic Short Course for Bloodstream Infections in Acute Myeloid Leukemia Patients With Febrile Neutropenia

Acute Myeloid Leukemia | Febrile Neutropenia | Bloodstream Infection

France
MacroGenics
National Institute of Allergy and Infectious Diseases (NIAID)

No longer available

Expanded Access to MGAWN1 in Subjects With Suspected West Nile Neuroinvasive Disease; Suspected West Nile Virus Infection; or Substantial Accidental Exposure

West Nile Virus Infection
Aesculap AG

Active, not recruiting

CoreHip - Post Market Clinical Follow-Up Study

Degenerative Osteoarthritis | Rheumatic Arthritis | Fractures, Hip | Necrosis, Femur Head

Germany, Switzerland
Stanford University
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Effects of Aging on Primary and Secondary Vaccine Responses in a 15-Year Longitudinal Cohort (SLVP033)

Hepatitis A | Influenza | Healthy Adults | Typhoid

United States
University of Kansas Medical Center

Recruiting

Comparing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (CRS-HIPEC) Using Mitomycin-C Versus Melphalan for Colorectal Peritoneal Carcinomatosis

ColoRectal Cancer | Cancer, Appendiceal

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

CPX-351 in Treating Patients With Relapsed or Refractory High Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia

Recurrent Chronic Myelomonocytic Leukemia | Refractory Chronic Myelomonocytic Leukemia | Blasts More Than 5 Percent of Bone Marrow Nucleated Cells | Recurrent High Risk Myelodysplastic Syndrome | Refractory High Risk Myelodysplastic Syndrome | Blasts 10-19 Percent of Bone Marrow Nucleated Cells and other conditions

United States
University of California, San Francisco

Completed

Efficacy of Bromocriptine For Fever Reduction in Acute Neurologic Injury (BFF)

Ischemic Stroke | Fever | Traumatic Brain Injury | Subarachnoid Hemorrhage | Intracerebral Hemorrhage | Subdural Hematoma

United States
West Virginia University

Completed

Unrelated Umbilical Cord Blood (UBC)Transplantation

Multiple Myeloma | Hodgkin Lymphoma | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Chronic Lymphocytic Leukemia (CLL) | Severe Aplastic Anemia | Acute Myelogenous Leukemia (AML) | Acute Lymphocytic Leukemia (ALL) | Chronic Myelogenous Leukemia (CML)

United States
ThermalCore Inc

Suspended

A Phase 1 Trial of Perfusion Induced Systemic Hyperthermia (PISH) Over Multiple Cycles for Terminal Ovarian Cancer (PISH-2)

Ovarian Cancer

United States
Sun Yat-sen University

Completed

Effect of Simvastatin on Cardiac Function

Rheumatic Heart Disease | Aneurysm | Congenital Heart Disease | Heart Valve Disease

China
Universitaire Ziekenhuizen KU Leuven

Recruiting

Register With Patients in Which Hyperthermic Intra-Peritoneal Chemotherapy (HIPEC) Was Performed (HIPEC)

Pseudomyxoma Peritonei | Peritoneal Carcinomatosis | Peritoneal Mesothelioma

Belgium
Applied Biological Laboratories Inc
Econometrica, Inc.

Completed

Alleviation of Common Cold Symptoms

Cough | Fever | Headache | Common Cold | Rhinorrhea | Sneezing | Pharyngitis | Congestion | Sore-throat | Sore Throats Viral | Malaise | Runny Nose

United States
Hospices Civils de Lyon

Unknown

Tolerance of Intraperitoneal (IP) Nivolumab After Extensive Debulking Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Ovarian Carcinoma (ICONIC)

Ovarian Cancer

France
The Netherlands Cancer Institute

Completed

Secondary Debulking Surgery +/- Hyperthermic Intraperitoneal Chemotherapy in Stage III Ovarian Cancer

Ovarian Cancer

Netherlands
University Hospital, Montpellier

Completed

Does Hirschsprung Disease Increase the Risk of Febrile Urinary Tract Infection in Children

Hirschsprung Disease | Febrile Urinary Tract Infection (Disorder)

France
Societe Francaise de Rhumatologie
Bordeaux PharmacoEpi

Recruiting

Observational Study in Patients Treated With JAK Inhibitors for Inflammatory Rheumatism (MAJIK) (MAJIK)

Rheumatoid Arthritis | Psoriatic Arthritis | Spondyloarthritis | Inflammatory Rheumatism

France
University of Colorado, Denver
GlaxoSmithKline

Completed

Evaluation of Moderate to Severe Influenza Outcomes in Children (M2SFlu)

Fever | Influenza | Otitis Media | Lower Resp Tract Infection | Encephalitic Infection | Myositis Viral

United States
Assistance Publique Hopitaux De Marseille

Completed

Does Etanercept Influence Tweak Modulation of Inflammation During Inflammatory Rheumatisms (Psoriatic Arthritis and Rheumatoid Arthritis)?

Rheumatoid Arthritis | Psoriatic Arthritis | Inflammatory Rheumatism

France
Duke University
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Recruiting

COVID-19 Vaccine Responses in PIDD Subjects

Common Variable Immunodeficiency | X-linked Agammaglobulinemia | Primary Immune Deficiency | Primary Antibody Deficiencies | CVID | XLA | Secondary Hypogammaglobulinemia

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Phase I Dose-finding Trial of Hyperthermic Intraperitoneal Paclitaxel Combined With Cisplatin

Ovarian Cancer | Paclitaxel | Hyperthermic Intraperitoneal Chemotherapy

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Efficacy of Neoadjuvant Hyperthermic Intraperitoneal Chemotherapy in Advanced High-grade Serous Ovarian Cancer (the NHIPEC Trial) (NHIPEC)

Neoadjuvant Chemotherapy | Hyperthermic Intraperitoneal Chemotherapy

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Treat-to-target by Email During Urate-lowering Therapy in Gout (GOUTEmail)

Hyperuricemia | Gout | Inflammatory Rheumatism | Posology Adjustment

France
Second Affiliated Hospital, School of Medicine,...
Zhejiang University

Recruiting

HIPEC in the Treatment of Stage IIc-IV Epithelial Ovarian Cancer After CRS (HIPECOC)

Ovarian Cancer | Hyperthermic Intraperitoneal Chemotherapy

China
University Hospital Center of Martinique

Completed

Seroprevalence of Chikungunya at the End of the First Chikungunya Outbreak in the French Antilles Within a Sample of Patients Treated for a HIV Infection (ChikVIH)

HIV Infections | Chikungunya Virus Infection

France
Blueprint Medicines Corporation

Terminated

(HARMONY) Study of BLU-701 in EGFR-mutant NSCLC

Neoplasms | Respiratory Tract Diseases | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Thoracic Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Neoplasms, Nerve Tissue | Non Small Cell Lung... and other conditions

United States
University Hospital, Bonn

Unknown

Safety and Pharmacokinetics of Intraoperative Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) With Cisplatin to Treat Platinum-sensitive Recurrent Ovarian Cancer (HIPEC ROC I)

Ovarian Cancer

Germany
St. Jude Children's Research Hospital
Baylor College of Medicine; Children's Hospital of Philadelphia; Dana-Farber... and other collaborators

Recruiting

Investigation of the Genetics of Hematologic Diseases

Myelodysplastic Syndromes | Sickle Cell Disease | Fanconi Anemia | Severe Congenital Neutropenia | Bone Marrow Failure Syndromes | Blood Coagulation Disorder | Erythrocyte Disorder | Leukocyte Disorder | Hemostasis | Dyskeratosis Congenita | Diamond-Blackfan Anemia | Congenital Thrombocytopenia | Myeloproliferative...

United States
Indonesia University

Recruiting

The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients

Rheumatic Heart Disease | ACE Inhibitor | Mitral Stenosis | Rheumatic Mitral Stenosis | Fibrosis; Heart

Indonesia
Huazhong University of Science and Technology
Qingdao University; Southern Medical University, China; Centers for Disease Control...

Unknown

Diet and Lifestyle Intervention Study in Postpartum Women in China

Constipation | Anemia | Fever | Hemorrhoids | Anal Fissure | Puerperal Infection | Breast Disease | Oral Ulcers

China
Centre Hospitalier Universitaire de Nice

Not yet recruiting

Cohort Project of Patients With Inflammatory Rheumatism (SMAP)

Rheumatoid Arthritis | Psoriatic Arthritis | Spondyloarthritis, Axial

France
Centre Hospitalier Universitaire de Nice

Active, not recruiting

Impact of Air Pollution on the Course of Inflammatory Rheumatism

Rheumatoid Arthritis | Psoriatic Arthritis | Ankylosing Spondylitis

France
Duke University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) (POPS or POP02)

Heart Failure | Pain | Pneumonia | Hypertension | Edema | Hemophilia | Insomnia | Pulmonary Arterial Hypertension | Coagulation Disorder | Asthma in Children | Down Syndrome | Attention Deficit Hyperactivity Disorder | Bronchopulmonary Dysplasia | Hypokalemia | Hyperphosphatemia | Primary Hyperaldosteronism | Adrenal Insufficiency and other conditions

United States, Canada
Peter MacCallum Cancer Centre, Australia
Melbourne Health; Westmead Hospital; Victorian Infectious Diseases Reference...

Completed

PET/CT and Bacterial/Fungal PCR in High Risk Febrile Neutropenia (PIPPIN)

Acute Myeloid Leukemia | Febrile Neutropenia | Acute Lymphoblastic Leukemia | Haematopoietic Stem Cell Transplant, Autologous | Haematopoietic Stem Cell Transplant, Allogeneic

Australia
Eli Lilly and Company

Active, not recruiting

A Study of Baricitinib (LY3009104) in Adult and Pediatric Japanese Participants With NNS/CANDLE, SAVI, and AGS

Aicardi Goutieres Syndrome | Nakajo-Nishimura Syndrome | Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature Syndrome | STING-Associated Vasculopathy With Onset in Infancy

Japan
Valneva Austria GmbH

Recruiting

A Clinical Phase 3 Study of VLA1553 in Adult Participants With Human Immunodeficiency Virus (HIV)

Chikungunya Virus Infection

Panama
Bavarian Nordic
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Safety, Tolerability and Immune Response of IMVAMUNE (MVA-BN)Smallpox Vaccine in Patients With Atopic Disorders

Dermatitis, Atopic | Hay Fever

Germany
Assiut University

Completed

N-acetylcysteine for Renal Protection in Patients With Rheumatic Heart Disease Undergoing Valve Replacement

Renal Dysfunction | Cardiac Surgery for Rheumatic Valvular Heart Disease

Egypt
Dr. med. Carlo Cereda
University Hospital Inselspital, Berne; CLINICA HILDEBRAND CENTRO DI RIABILITAZIONE... and other collaborators

Unknown

Rehabilitation Combined With Bihemispherictranscranial Direct Current Stimulation in Subacute Ischemic Stroke (RECOMBINE)

Ischemic Stroke | First Ever Clinical Stroke | Subacute Phase | Persistent Hemiparesis of Upper Extremity

Switzerland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Lenalidomide and Ofatumumab in Treating Participants With Previously Treated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Fatigue | Thrombocytopenia | Fever | Chronic Lymphocytic Leukemia | Lymphadenopathy | Small Lymphocytic Lymphoma | Hypogammaglobulinemia | Lymphocytosis | Night Sweats | Paraproteinemia

United States
Scripps Health

Completed

Unrelated Donor Stem Cell Transplantation

Myelodysplastic Syndromes | Multiple Myeloma | Hodgkin's Lymphoma | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Acute Myelogenous Leukemia | Chronic Myelogenous Leukemia | Small Lymphocytic Lymphoma | Paroxysmal Nocturnal Hemoglobinuria | Severe Aplastic Anemia | Myeloproliferative... and other conditions

United States
UMC Utrecht
Center for Translational Molecular Medicine; Dutch Cancer Society; Vrienden UMC...

Recruiting

Image-guided Targeted Doxorubicin Delivery With Hyperthermia to Optimize Loco-regional Control in Breast Cancer (i-GO)

Breast Cancer | Breast Neoplasms | Metastatic Cancer | Metastatic Breast Cancer | Stage IV Breast Cancer | Invasive Ductal Breast Cancer | Invasive Ductal Carcinoma of Female Breast | Adenocarcinoma Breast

Netherlands
Aesculap AG

Active, not recruiting

Plasmafit® Revision Structan® Hip Endoprosthesis Cup

Arthroplasty Complications | Prosthesis Failure | Osteolysis | Degenerative Osteoarthritis | Rheumatic Arthritis | Fractures, Hip | Instability of Prosthetic Joint | Femoral Head Avascular Necrosis

Germany
University Hospital, Toulouse

Unknown

Fertility Study of Women With Chronic Inflammatory Rheumatism (FERTIRHUM)

Arthritis, Rheumatoid | Arthritis, Psoriatic | Ankylosing Spondylitis | Chronic Juvenile Arthritis

France
Zhongnan Hospital

Active, not recruiting

Cytoreductive Surgery(CRS) Plus Hyperthermic Intraperitoneal Chemotherapy(HIPEC) With Lobaplatin in Advanced and Recurrent Epithelial Ovarian Cancer (HIPECOV)

Ovarian Neoplasms | Ovarian Cancer | Epithelial Ovarian Cancer | Ovarian Cancer, Epithelial | Hyperthermic Intraperitoneal Chemotherapy(HIPEC) | Ovary Neoplasm

China
Catholic University of the Sacred Heart

Unknown

Hyperthermic Intra-peritoneal Chemotherapy (HIPEC) in Ovarian Cancer Recurrence (HORSE)

First Recurrence of Ovarian Cancer

Italy
ProgenaBiome

Recruiting

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Alzheimer's Disease

Alzheimer Disease | Alzheimer Disease, Early Onset | Alzheimer Disease, Late Onset | Alzheimer Disease 1 | Alzheimer Disease 2 | Alzheimer Disease 3 | Alzheimer Disease 4 | Alzheimer Disease 7 | Alzheimer Disease 17 | Alzheimer Disease 5 | Alzheimer Disease 6 | Alzheimer Disease 8 | Alzheimer Disease 10 | Alzheimer... and other conditions

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Shenshan Medical Center, Memorial Hospital of Sun Yat-sen University

Not yet recruiting

Administration of Hyperthermic Intraperitoneal Chemotherapy in the General Ward (GARD-HIPEC)

Epithelial Ovarian Cancer

China
Centre Oscar Lambret

Recruiting

Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Ovarian Cancer (CHIPPI) (CHIPPI)

Ovarian Cancer | Ovarian Carcinoma | Ovary Neoplasms

France, Belgium

Clinical Trials on Moderate and Severe COVID-19

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Drug Interventions

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CROs in South Africa

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