Clinical Trials on Moderate to Severe Persistent Bronchial Asthma

Total 517 results

Fresenius Kabi SwissBioSim GmbH

Completed

MSB11022 in Moderate to Severe Rheumatoid Arthritis (Auriel-RA)

Moderate to Severe Rheumatoid Arthritis

Bulgaria, United Kingdom, Hungary, Czechia, Poland, Germany
University of Padova

Unknown

Evaluation of Lymphocytic Infiltrate, Dendritic Cells and Cytokines Expression in Psoriatic Lesion and Normal Skin Before and After TNF Alfa Inhibitors Therapy (ELIDACE)

Moderate to Severe Psoriasis. | Absolute Number, Density of Immune Infiltrate and Dendritic Cells and Inflammatory Cytokines Expression Pattern.

Italy
University of Leicester
Genentech, Inc.; Medical Research Council; Queen's University, Belfast

Active, not recruiting

Refractory Asthma Stratification Programme (RASP) Bronchoscopy Study

Persistent Asthma

United Kingdom
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

Study to Assess the Efficacy and Safety of Beclomethasone Dipropionate in Adolescent and Adult Patients 12 Years of Age and Older With Persistent Asthma

Persistent Asthma

United States
Children's Hospital Medical Center, Cincinnati
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Adolescent Controlled Text Messaging to Improve Asthma Medication Adherence in Primary Care (ACT Me)

Persistent Asthma

United States
University of Limpopo

Unknown

Effect of Vitamin D Supplementation on the Control of Asthma in Children at a South African Academic Hospital

Persistent Asthma

South Africa
Amgen

Terminated

Evaluating Etanercept Use in Patients With Moderate to Severe Rheumatoid Arthritis Who Have Lost Response to Adalimumab (ROCkIES)

Moderate to Severe Rheumatoid Arthritis

United States, Canada, Puerto Rico
AbbVie (prior sponsor, Abbott)
University Health Network, Toronto

Completed

Real Life Evaluation of Rheumatoid Arthritis in Canadians Taking HUMIRA (REACH)

Moderate-to-severe Rheumatoid Arthritis
ImmuneMed, Inc.

Not yet recruiting

A Study to Assess the Efficacy and Safety of Burfiralimab (hzVSF-v13) and DMRD (Disease-modifying Antirheumatic Drug)

Moderate to Severe Rheumatoid Arthritis

Netherlands
Bracco Diagnostics, Inc

Completed

Follow-up Study to Previous CARE Trial

Moderate to Severe Chronic Kidney Disease

United States
Eurofarma Laboratorios S.A.

Not yet recruiting

Non-Inferiority,Combination Formoterol/FluticasonexAlenia®Formoterol/Budesonide for Asthma in Brazil (FORASMA)

Moderate Asthma

Brazil
Regeneron Pharmaceuticals
Sanofi

Completed

Study of Safety, Tolerability, and Pharmacokinetics of Multiple Ascending Doses of REGN3500 in Adults With Moderate Asthma

Asthma | Moderate Asthma

United Kingdom
Dayton Children's Hospital
Cairify LLC; Copeland LP

Active, not recruiting

Indoor Air Quality Asthma Study: The Effect of Indoor Air Quality and Mitigation of Same on Persistent Asthma (IAQ)

Persistent Asthma

United States
National Institute of Allergy and Infectious Diseases...
Rho Federal Systems Division, Inc.; Inner-City Asthma Consortium

Completed

Cockroach Immunotherapy in Children and Adolescents (CRITICAL)

Persistent Asthma

United States
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A 12-week Safety and Efficacy Study of Beclomethasone Dipropionate (80 and 160 mcg/Day) Delivered Via Breath-Actuated Inhaler (BAI) in Patients >=12 Years Old With Persistent Asthma

Persistent Asthma

United States
Mundipharma Pharmaceuticals S.L.
Alpha Bioresearch S.L.; Dynamic Solutions

Withdrawn

Efficiency Control of Fluticasone/Formoterol K-haler (Medium Strength) vs ICS/LABA (High Strength) in Asthma Patients

Persistent Asthma
Medical Acoustics LLC
NYSTAR

Completed

Impact of Lung Flute Therapy on Asthma

Persistent Asthma

United States
Lupin, Inc.

Completed

Pharmacodynamic Bioequivalence of Metered Dose Inhalers of Albuterol Sulfate in Patients With Stable Mild Asthma

Mild Persistent Asthma

United States
Novartis Pharmaceuticals
Genentech, Inc.

Completed

Evaluate the Effect of Omalizumab on Markers of Asthma Impairment in Patients With Persistent Allergic Asthma

Persistent Allergic Asthma

United States
Kyowa Kirin Co., Ltd.

Active, not recruiting

A Phase 3 Study of KHK4827 in Patients With Systemic Sclerosis

Moderate to Severe Systemic Sclerosis

Japan
Synta Pharmaceuticals Corp.

Completed

A Randomized, Double-blind, Placebo-controlled Clinical Study of the Oral IL-12/23 Inhibitor, STA-5326 Mesylate, Administered to Patients With Rheumatoid Arthritis to Determine Safety, Tolerability, Pharmacokinetic and Synovial Tissue Outcomes

Active, Moderate to Severe Rheumatoid Arthritis

Netherlands
Emphycorp

Terminated

Safety and Efficacy Study of the Use of Sodium Pyruvate Bronchodilation in Asthmatics

Moderate Asthma

United States
Shanghai Vinnerna Biosciences Co., Ltd.
Sponsor GmbH

Terminated

Efficacy and Safety of JT001 (VV116) Compared With Favipiravir

Moderate to Severe COVID-19

China, Uzbekistan
Novartis Pharmaceuticals
Genentech, Inc.

Completed

Omalizumab in Patients With Moderate to Severe Persistent Allergic Asthma Not Adequately Controlled Despite GINA (2009) Step 4 Therapy

Persistent Allergic Asthma

China
Royal Victoria Hospital, Canada

Not yet recruiting

Monthly Versus Daily Buprenorphine Formulations for Treatment of Opiate Use Disorder (STOPIT)

Moderate to Severe Opioid Use Disorder

Canada
Indivior Inc.

Active, not recruiting

Buprenorphine Extended-Release Subcutaneous Injection (RBP-6000) in High-risk Users

Moderate to Severe Opioid-use Disorder

United States, Canada
Zhejiang Hisun Pharmaceutical Co. Ltd.

Completed

Phase III Clinical Trial Comparing the Safety, Efficacy, and Immunogenicity of Recombinant Anti-interleukin-6 Receptor Humanized Monoclonal Antibody Injection in Combination With Methotrexate and Jamelor ® in the Treatment of Moderate to Severe Rheumatoid Arthritis

Moderate to Severe Active Rheumatoid Arthritis

China
Koneksa Health

Completed

Study Comparing At-Home Mobile Spirometry to In-Clinic in Moderate Asthma Participants Taking Long-Acting Beta Agonist (LEARN)

Moderate Asthma

United States
Guangzhou Institute of Respiratory Disease

Unknown

Effect of Bronchial Thermoplasty on Moderate Bronchial Asthma in China

Moderate Asthma

China
Gert-Jan Braunstahl
Genzyme, a Sanofi Company

Completed

Real Life Experience Survey of Dupilumab in the Netherlands (RELYonDupi)

Severe Asthma

Netherlands
AstraZeneca

Completed

Observational Retrospective Study on Clinical Outcomes of Patients Receiving Benralizumab in Spain. (ORBE-II)

Severe Asthma

Spain
Incyte Corporation

Withdrawn

A Study to Evaluate the Safety and Efficacy of Itacitinib in Moderate to Severe Ulcerative Colitis

Moderate to Severe Ulcerative Colitis
Mundipharma Research Limited

Completed

Knemometry Study to Compare the Systemic Safety of Flutiform pMDI, Fluticasone pMDI and Beclometasone Autohaler in Paediatric Subjects Aged 5 to Less Than 12 Years.

Mild Persistent Asthma

Denmark
CHA University
Merck Sharp & Dohme LLC

Completed

Response of FeNO, Small Airway Dysfunction and Lung Heterogeneity to 2-week Montelukast Treatment in Asthmatic Children.

Mild Persistent Asthma
MedImmune LLC

Terminated

A Study to Assess Pharmacokinetics, Safety and Tolerability of Multiple Doses of CAT-354 in Subjects With Moderate Asthma

Moderate Asthma

United Kingdom
Bio-Thera Solutions

Completed

Evaluate the Pharmacokinetics of BAT2606 Injection in Healthy Chinese Male Subjects

Severe Asthma

China
Ganzhou Hemay Pharmaceutical Co., Ltd

Recruiting

Phase II Study of Hemay005 in Patients With Active Ulcerative Colitis

Moderate to Severe Ulcerative Colitis

China
Sixth Affiliated Hospital, Sun Yat-sen University

Recruiting

A Cohort Study Comparing IFX to CS for Moderate to Severe UC (INSURE)

Moderate to Severe Ulcerative Colitis

China
Suzhou Connect Biopharmaceuticals, Ltd.

Completed

A Study Assessing the Efficacy and Safety of CBP-307 in Subjects With Moderate to Severe Ulcerative Colitis (UC)

Moderate to Severe Ulcerative Colitis

United States, China, Pakistan, Ukraine
Medivation, Inc.
Pfizer

Terminated

A Safety and Efficacy Study Evaluating Dimebon (Latrepirdine) in Patients With Moderate to Severe Alzheimer's Disease (CONTACT)

Moderate to Severe Alzheimer

Chile, United Kingdom
Novartis Pharmaceuticals

Completed

Indacaterol EfectIveness In COPD Patients With Tuberculosis History (INFINITY)

Patients With Moderate-to-severe COPD With Destroyed Lung by Tuberculosis

Korea, Republic of
Wenzhou Medical University

Completed

Efficacy of Nonsteroidal Anti-inflammatory Drugs in Treatment of Moderate and Severe Dry Eye Disease

Moderate to Severe Dry Eye Syndrome

China
Invion, Inc.

Unknown

Efficacy and Safety of Beta-adrenoceptor Inverse Agonist, Nadolol, in Mild Asthma

Mild Persistent Asthma, Uncomplicated

United States
Mundipharma Research GmbH & Co KG

Completed

A Study to Demonstrate the Analgesic Efficacy of Oxycodone/Naloxone Prolonged Release Tablets in Addition to Pregabalin Compared to Pregabalin Alone in Opioid-naïve Subjects Treated With Pregabalin Suffering From Moderate to Severe Pain Due to Diabetic Polyneuropathy

Moderate to Severe Pain Due to Diabetic Polyneuropathy

Germany
Hoffmann-La Roche
Pfizer

Completed

A Study to Evaluate the Efficacy and Safety of PF-06480605 in Adults With Moderate to Severe Ulcerative Colitis

Moderate to Severe Ulcerative Colitis

United States, Australia, Thailand, Poland, Russian Federation, Japan, Colombia, Spain, Turkey, Romania, India, Slovakia, France, Hungary, South Africa, Belgium, Bulgaria, Germany, Italy, Mexico, Serbia, Ukraine, United Kingdom
Novartis Pharmaceuticals

Terminated

Study of Safety of Foradil in Patients With Persistent Asthma

Persistent Asthma

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Levosimendan Versus Placebo Before Tricuspid Valve Surgery in Patients With Right Ventricular Dysfunction (LEONARD)

Patients Referred for an Isolated or a Combined Surgical Correction of Functional Moderate to Severe Tricuspid

France
University of Illinois at Chicago
Johnson & Johnson Vision Care, Inc.

Unknown

Senofilcon A Lenses in Moderate to Severe Dry Eye Disease

Moderate to Severe Dry Eye Disease

United States
Asan Medical Center

Suspended

Fluvoxamine for Adults With Mild to Moderate COVID-19

Coronavirus Infection | Severe Acute Respiratory Syndrome Coronavirus 2 | Mild to Moderate COVID-19

Korea, Republic of
Samsung Pharmaceutical Co., Ltd.

Not yet recruiting

GV1001 Subcutaneous for the Treatment of Moderate to Severe Alzheimer's Disease(AD)

Moderate to Severe Alzheimer's Disease

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